Neurotensin effects on calcium/calmodulin-dependent protein phosphorylation in rat neostriatal slices.

abstract：:In anaesthetized cats, medial gastrocnemius motor units (MUs) were stimulated with random sequences (mean rates between 6 and 12 pps) of electrical pulses delivered to their axons in small ventral root filaments. Muscle tension was recorded under isometric conditions, and spike trains of muscle spindle afferents were ...

journal_title：Brain research

authors： Christakos CN,Windhorst U

更新日期：1986-02-19 00:00:00

abstract：:Altered expression of neurotrophins may contribute to the pathogenesis of schizophrenia. Several studies suggest sex steroid hormones may be involved in the regulation of brain-derived neurotrophic factor (BDNF) signaling, as well as the symptoms of schizophrenia. This study aimed to identify sex differences in BDNF-T...

journal_title：Brain research

authors： Hill RA,van den Buuse M

更新日期：2011-04-12 00:00:00

abstract：:Co-activation of group I metabotropic glutamate (mGlu) receptors and adenosine receptors resulted in an augmented cyclic AMP response in primary cultures of rat striatal neurones. L-glutamate and the selective group I agonist, (S)-dihydroxyphenylglycine (S-DHPG) evoked concentration-dependent potentiations of cyclic A...

journal_title：Brain research

authors： Cartmell J,Goepfert F,Knoflach F,Pink JR,Bleuel Z,Richards JG,Schaffhauser H,Kemp JA,Wichmann J,Mutel V

更新日期：1998-04-27 00:00:00

abstract：:To understand the role of hypothalamic dopamine in thermoregulation, single unit activity was recorded in vitro, from constantly perfused tissue slices of rat preoptic area and anterior hypothalamus, PO/AH. The firing rate and thermosensitivity of individual PO/AH neurons were determined before, during and after tissu...

journal_title：Brain research

authors： Scott IM,Boulant JA

更新日期：1984-07-23 00:00:00

abstract：:Different doses of angiotensin II (AII) or angiotensin III (AIII) microinjections into the zona incerta have been studied on drinking of rats in separate experiments during the consequent 60-min-daily-drinking period. Also, the dipsogen power of only the effective dose of AII and AIII was compared to vehicle treated r...

journal_title：Brain research

authors： Bagi EE,Fekete E,Lénárd L

更新日期：2003-07-11 00:00:00

abstract：:Intravenous administration of the cholecystokinin (CCK) antagonist lorglumide (LORG) reversed chronic haloperidol (CHAL)-induced depolarization inactivation (DI) of dopamine (DA) cells in both the A9 and A10 areas. Moreover, microinjection of LORG, but not naloxone, directly into the medial nucleus accumbens (mNAc) do...

journal_title：Brain research

authors： Jiang LH,Kasser RJ,Wang RY

更新日期：1988-11-08 00:00:00

abstract：:Binding sites of atrial natriuretic peptide in the cerebral microvessels and choroid plexus of spontaneously hypertensive rats (SHR) and Wistar Kyoto control rats (WKY) were measured. In the microvessels, the number of ANP binding sites was lower in SHR than WKY, but there was no difference in affinity of binding site...

journal_title：Brain research

authors： Okazaki M,Kobayashi H,Kuroiwa A,Izumi F

更新日期：1990-06-04 00:00:00

abstract：:The effects of estrus and prolonged estradiol benzoate (EB) treatment on estrogen receptor-like immunoreactivity (ER-LI) were studied in the female Brazilian opossum (monodelphis domestica) brain. In general, both estrus animals and EB treated animals had reduced ER-LI in specific brain regions when compared to ovarie...

journal_title：Brain research

authors： Pearson PL,Ross LR,Jacobson CD

更新日期：1993-07-16 00:00:00

abstract：:Nuclear factor κB (NFκB) signaling plays ubiquitous roles in inflammation, immune response and neurogenesis. G protein-coupled receptor kinase 5 (GRK5) can protect neurons from degeneration. GRK5 also mediates tumor necrosis factor-α (TNFα)-induced NFκB signaling through the phosphorylation of IκBα. Here, we show that...

journal_title：Brain research

authors： Zhang Y,Shen GL,Shangguan LJ,Yu Y,He ML

更新日期：2015-05-22 00:00:00

abstract：:Intracerebroventricular (i.c.v.) infusion of sodium in rats increases cerebrospinal fluid (CSF) [Na], mimicking the effects of a high salt diet in salt-sensitive strains and causing sympathetic hyperactivity and a pressor response that are mediated via both an endogenous brain ouabainlike substance (OLS) and the brain...

journal_title：Brain research

authors： Van Huysse JW,Hou X

更新日期：2004-09-24 00:00:00

abstract：:The functional organization of projections from the cerebellar subcortical nuclei to the motor cortex through the nucleus ventralis lateralis (VL) of the thalamus was studied using tungsten microelectrodes for stimulation and recordings in acute and chronic cats. The following results were obtained. (1) Microstimulati...

journal_title：Brain research

authors： Asanuma H,Hunsperger RW

更新日期：1975-11-07 00:00:00

abstract：:Kindling of the ventral tegmental area (VTA), a major source of the mesolimbic dopamine pathway, was examined in rats. We applied two quantitative measurements of dopamine sensitivity before and 2 weeks after VTA kindling (20 times electrical stimulations (100 microA at 1 min intervals) delivered once per day for 14 c...

journal_title：Brain research

authors： Watanabe T,Morimoto K,Nakamura M,Hirao T,Ninomiya T,Ando N,Suwaki H

更新日期：2004-04-02 00:00:00

abstract：:Systemic administration of 3-nitropropionic acid (3-NP) results in striatal atrophy by irreversibly inhibiting the citric acid cycle, and thereby resulting in cellular ATP depletion. The neuropathological outcome following 3-NP injections is thought to resemble that seen in Huntington's disease (HD) [1]. The current s...

journal_title：Brain research

authors： Koutouzis TK,Borlongan CV,Scorcia T,Creese I,Cahill DW,Freeman TB,Sanberg PR

更新日期：1994-05-23 00:00:00

abstract：:The possible interference of nitric oxide (NO) in glucose metabolism was studied in activated astrocytes. Lipopolysaccharide (LPS) treatment triggered a NO-mediated increase in glucose consumption and lactate production, suggesting an enhanced rate of glycolysis. Active glycogen synthesis was also observed after LPS t...

journal_title：Brain research

authors： Almeida A,Cidad P,Bolaños JP

更新日期：2002-07-26 00:00:00

abstract：:The pattern of generation of neurons in the albino rat superior colliculus has been studied in adult and fetal material. Neurons are generated between embryonic days 12 to 17, with rostrolateral colliculus in advance of caudomedial parts. More of the cells contributing to the deeper layers are generated early, while m...

journal_title：Brain research

authors： Mustari MJ,Lund RD,Graubard K

更新日期：1979-03-23 00:00:00

abstract：:Movements of medium and large sized membranous organelles (0.5-1 microns in diameter) were visualized within segments of the crab walking leg nerve with Nomarski differential interference contrast optics and subjected to video contrast enhancement. Accessibility to the axoplasm was demonstrated by intra-axonal fluores...

journal_title：Brain research

authors： Moshiach S,Nelson TJ,Sanchez-Andres JV,Sakakibara M,Alkon DL

更新日期：1993-03-12 00:00:00

abstract：:Developmental delay, cognitive impairment, and refractory epilepsy are the most frequent consequences found in patients suffering from malformations of cortical development (MCD). However, therapeutic options for these psychiatric and neurological comorbidities are currently limited. The development of white matter un...

journal_title：Brain research

authors： Ma L,Yang F,Zhao R,Li L,Kang X,Xiao L,Jiang W

更新日期：2015-10-05 00:00:00

abstract：:With the use of [3H]p-aminoclonidine (PAC), alpha 2-adrenergic binding sites were mapped in the brain of the Japanese quail (Coturnix coturnix japonica). The sites were labeled with the use of in vitro quantitative autoradiography. Special attention was given to areas implicated in the control of sexually dimorphic re...

journal_title：Brain research

authors： Ball GF,Nock B,McEwen BS,Balthazart J

更新日期：1989-07-03 00:00:00

abstract：:We have investigated the role of NMDA receptors in the rat dorsal horn in mediating neuronal responses to noxious hindlimb ischemia, induced by acute occlusion of the femoral artery, as well as in the hyperalgesia evident when noxious mechanical stimuli were applied to the ischemic limb. Two specific NMDA antagonists,...

journal_title：Brain research

authors： Sher GD,Mitchell D

更新日期：1990-07-02 00:00:00

abstract：:The diagonal band of Broca (dbB) is involved in central cardiovascular control. In the present study we compared the effects of microinjections of L-glutamate into the dbB of unanesthetized rats with those observed after the injection of L-glutamate into the same area in urethane-anesthetized rats. The microinjection ...

journal_title：Brain research

authors： Tavares RF,de Aguiar Corrêa FM

更新日期：2003-01-10 00:00:00

abstract：:The effects of axotomy, chemical sympathectomy and preganglionic denervation on the expression of the neuropeptides, pituitary adenylate cyclase-activating peptide (PACAP), galanin (GAL), and the PACAP type 1 receptor in the rat superior cervical ganglion (SCG) were investigated by immunocytochemistry, in situ hybridi...

journal_title：Brain research

authors： Moller K,Reimer M,Ekblad E,Hannibal J,Fahrenkrug J,Kanje M,Sundler F

更新日期：1997-11-14 00:00:00

abstract：:Histamine is one of the neurotransmitters suppressing appetite, but the interactions of histaminergic neurons with other neurons in satiety centers have not been clarified. Noradrenaline in the para-ventricular nucleus (PVN) has been shown to stimulate feeding. This study was designed to determine whether histamine mo...

journal_title：Brain research

authors： Kurose Y,Terashima Y

更新日期：1999-05-15 00:00:00

abstract：:Glycoprotein M6a is a neuronally expressed member of the proteolipid protein (PLP) family of tetraspans. In vitro studies suggested a potential role in neurite outgrowth and spine formation and previous investigations have identified M6a as a stress-regulated gene. To investigate whether the distribution of M6a correl...

journal_title：Brain research

authors： Cooper B,Werner HB,Flügge G

更新日期：2008-03-04 00:00:00

abstract：:The time-course of intracellular glutathione (GSH) values after incubation with L-buthionine-(S,R)-sulfoximine (BSO), a selective inhibitor of gamma-glutamylcysteine synthetase, showed that glutathione turns over with a half-life of 5 h. Intracellular GSH was assayed by flow cytometry using three different methods. As...

journal_title：Brain research

authors： Devesa A,O'Connor JE,Garciá C,Puertes IR,Viña JR

更新日期：1993-08-06 00:00:00

abstract：:Neovascularization within syngeneic rat fetal neocortical grafts transplanted into a previously prepared cavity in the cerebral cortex was studied 1 to 3 months after transplantation, utilizing scanning electron microscopy of vascular corrosion casts. The grafts were easily identified and the outer surface of the graf...

journal_title：Brain research

authors： Miyoshi Y,Date I,Ohmoto T

更新日期：1995-05-29 00:00:00

abstract：:To determine the effect of thyroid hormones (TH) on cerebral tissue malondialdehyde (MDA) content and accumulation of MDA-bound proteins, hyperthyroid rats and hypothyroid rats were compared to euthyroid controls. Hyperthyroidism was induced by daily injection of l-3,5, 3'-triiodothyronine (15 ug (100 g)-1) intraperit...

journal_title：Brain research

authors： Chehade J,Kim J,Pinnas JL,Mooradian AD

更新日期：1999-05-22 00:00:00

abstract：:The aim of this study was to examine: (1) whether long-term potentiation (LTP) can be induced in slices from adult rat visual cortex under conditions where inhibition is not antagonized, and (2) the role of N-methyl-D-aspartate (NMDA) receptors in its induction. The field potential elicited in layer III in response to...

journal_title：Brain research

authors： Aroniadou VA,Teyler TJ

更新日期：1992-07-03 00:00:00

abstract：:Antagonism of the alpha receptor sub-type at gamma-aminobutyric acid (GABA) recognition sites in developing pigs was evaluated using the GABAA receptor antagonist bicuculline. The effect of bicuculline infusions was to produce an increase of phrenic and hypoglossal discharge amplitudes. This bicuculline-induced effect...

journal_title：Brain research

authors： Steele AM,Siddiqi ZA,Sica AL

更新日期：1994-07-04 00:00:00

abstract：:From measured effects of amino acids on synaptosomal tyrosine uptake and from published data on human CNS levels of amino acids hypothetical calculations were made to compare CNS tyrosine availability for catecholamine synthesis in the hyperphenylalaninemic and non-hyperphenylalaninemic condition. These calculations i...

journal_title：Brain research

authors： Peterson NA,Shah SN,Raghupathy E,Rhoads DE

更新日期：1983-08-01 00:00:00

abstract：:Activated monocytes/macrophages are known to release toxic materials. Identification of these materials is important for developing more effective treatments for inflammatory disorders where self attack occurs. We stimulated human monocytes and THP-1 cells with LPS/IFNγ and measured the toxic effects of their conditio...

journal_title：Brain research

authors： Lee M,Suk K,Kang Y,McGeer E,McGeer PL

更新日期：2011-07-11 00:00:00