Abstract：
:From measured effects of amino acids on synaptosomal tyrosine uptake and from published data on human CNS levels of amino acids hypothetical calculations were made to compare CNS tyrosine availability for catecholamine synthesis in the hyperphenylalaninemic and non-hyperphenylalaninemic condition. These calculations indicate an approximately two-fold reduction in the availability of tyrosine in phenylketonuria that is due solely to a reduction in CNS tyrosine alone.
journal_name
Brain Resjournal_title
Brain researchauthors
Peterson NA,Shah SN,Raghupathy E,Rhoads DEdoi
10.1016/0006-8993(83)90380-3subject
Has Abstractpub_date
1983-08-01 00:00:00pages
189-93issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(83)90380-3journal_volume
272pub_type
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