Abstract：
:A combination of electron microscopic autoradiography and immunocytochemistry was used to examine the connections between serotoninergic axons and dopaminergic neurons of the arcuate nucleus of the rat hypothalamus. The serotoninergic elements were identified after selective uptake of tritiated serotonin and the dopaminergic neurons with tyrosine hydroxylase cytochemistry. Synaptic junctions between labeled serotoninergic nerve endings and tyrosine hydroxylase-immunoreactive neurons were observed, providing a structural basis for a direct influence of serotoninergic elements on tuberoinfundibular dopaminergic neurons.
journal_name
Brain Resjournal_title
Brain researchauthors
Kiss J,Halász Bdoi
10.1016/0006-8993(86)90841-3subject
Has Abstractpub_date
1986-02-05 00:00:00pages
284-94issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(86)90841-3journal_volume
364pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Monkeys were trained to depress a hold key for a period of 2 sec. After this hold period, either a red or a green cue lamp appeared in random sequence. The red lamp required the monkey to move his hand from the hold key to a target button within 1 sec of the cue presentation. The green lamp required continued depressi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(76)90986-0
更新日期：1976-01-09 00:00:00
abstract：:The aim of this study was to identify the medullary vagal nuclei involved in the different phases of swallowing activated physiologically in a species with an esophagus similar to human. In decerebrate cats, the pharyngeal (0.5-1.0 ml water in pharynx (N=6)) or esophageal (1-3 ml air in esophagus (N=5)) phases of swal...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.03.061
更新日期：2004-07-16 00:00:00
abstract：:We have examined, at the light microscope level, putative direct synaptic interconnections, via motor axon collaterals, between type-identified triceps surae alpha-motoneurons labeled by intracellular injection of HRP. The results indicate that monosynaptic recurrent contacts can occur between synergist motoneurons (i...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90937-5
更新日期：1984-08-06 00:00:00
abstract：:Conditioned place preference and locomotor sensitization are rodent behavioral models commonly used to investigate the actions of drugs of abuse. However, few studies have examined both paradigms in the same group of animals. We were interested in developing a combined protocol which successfully induced both conditio...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.03.054
更新日期：2008-06-05 00:00:00
abstract：:The effects of the 8-alpha-amino-ergoline CU 32-085 on central dopamine neuronal systems was investigated. Two h after administration of CU 32-085 a slight increase of dopamine levels was observed in the nucleus caudatus-putamen. Radioligand binding studies in vitro have shown that CU 32-085 has a low affinity for str...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91044-3
更新日期：1985-03-04 00:00:00
abstract：:We used two approaches to test the possibility that changes in presynaptic calcium currents might be responsible for the long-term potentiation (LTP) effect induced by high-frequency stimulation in area CA1 of hippocampal slices. In a first series of experiments, we compared the effect of LTP induction on paired-pulse...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)91631-4
更新日期：1989-02-13 00:00:00
abstract：:Neurofilament expression in peripheral olfactory neurons of adult rats was investigated by immunoblotting and immunohistochemistry using monoclonal antibodies specific for each of the 3 neurofilament proteins. Immunoblotting analysis of olfactory epithelium extracts demonstrated the presence of only the 200 kDa (NFH) ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)90416-s
更新日期：1991-05-31 00:00:00
abstract：:The recently developed technique of in vivo dialysis has permitted us to make direct measurements of serotonin release in a specific region of the spinal cord and to relate this to changes in blood pressure elicited by chemical stimulation of the brainstem. In the present experiments we have shown that chemical stimul...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91318-1
更新日期：1986-02-26 00:00:00
abstract：:Intracerebral administration of 6-hydroxydopamine (6-HDA) along the dorsal noradrenergic bundle produced a gradual and long-lasting decrease of norepinephrine (NE) in hippocampus. This decrease in NE levels initially was accompanied by a parallel decrease in the activity of the rate-limiting enzyme for NE biosynthesis...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(84)90056-8
更新日期：1984-12-24 00:00:00
abstract：:Binding activities specific for each of [3H]prostaglandin (PG) D2, E2 and F2 alpha were detected in the P2 fraction of the human brain homogenates. The bindings were time-dependent, saturable and of high affinity; Kd values were 30 nM for all the PG bindings. Regional distribution of these binding activities was deter...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91358-7
更新日期：1985-09-02 00:00:00
abstract：:Histochemical investigation by means of light and electron microscopy revealed the presence of dipeptidylpeptidase IV activity in Meissner corpuscles of macaque glabrous skin. The enzyme activity was found in fibroblast-like cells forming an incomplete capsule around the Meissner corpuscle. Distinct electron-dense rea...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90739-1
更新日期：1988-09-27 00:00:00
abstract：:One monoclonal antibody 115A10 (MAb 5A10) specifically stained a subpopulation of retinal bipolar cells in various vertebrates. In the bullfrog retina, MAb 5A10 stained the large bipolar cells, but not the small bipolar cells. Labeling of the living bipolar cells was observed in isolated cell preparation of the frog r...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90919-x
更新日期：1987-07-28 00:00:00
abstract：:The expression of the immediate-early gene c-fos was used as a marker of neuronal activity to investigate the cervical spinal interneuron populations involved in the corticomotoneuronal pathway. Adult rats received unilateral kainate injections in the forelimb area of the primary motor cortex. After a survival period ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00365-4
更新日期：1996-06-24 00:00:00
abstract：:The immunohistochemical localization of an endogenous lectin R1 isolated from the rat cerebellum was studied during its postnatal development. The lectin is present in the cerebellum from birth to adulthood, essentially in lysosomes, multivesicular bodies, and parts of the endoplasmic reticulum, principally of large a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(85)90148-8
更新日期：1985-01-01 00:00:00
abstract：:Injury to the central or peripheral nervous systems leads to the loss of cognitive and/or sensorimotor capabilities that still lack an effective treatment. Although injury to the nervous system involves multiple and complex molecular factors, alteration to protein homeostasis is emerging as a relevant pathological mec...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2016.04.053
更新日期：2016-10-01 00:00:00
abstract：:We studied whether, similarly to the auditory modality, short-period temporal integration processes occur in vision. Event-related potentials (ERP) were recorded for occasional stimulus omissions from sequences of patterned visual stimuli. A posterior negative component emerged only when the constant stimulus onset as...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.05.034
更新日期：2006-08-09 00:00:00
abstract：:Chronic neuropathic pain has demonstrated that coexisting psychiatric disorders are associated with disability and poorer treatment outcomes. Hyperpolarization-activated cyclic nucleotide-gated (HCN, Ih) channels play a major role in pain via hyperexcitability and facilitation of ectopic firing in neurons. Neuronal hy...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2019.03.036
更新日期：2019-08-15 00:00:00
abstract：:Intracerebral injection of kainic acid (KA) in rat brain was previously found to cause altered immunohistochemical recognition of connexin-43 (Cx43) epitopes (epitope masking) with different sequence-specific antibodies against this gap junction protein. We demonstrate here that similar alterations occur when nitrocel...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)00337-p
更新日期：1995-06-12 00:00:00
abstract：:A chronic diet of ethanol has detrimental effects on the cholinergic system in adult humans and rats. This study examined the effects of chronic exposure to dietary ethanol on the anatomical organization of true acetylcholinesterase (AChE) active elements in rat cerebral cortex. We focused on the somatosensory cortex ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90753-a
更新日期：1993-11-05 00:00:00
abstract：:Significant insights into the dynamics of neuronal populations have been gained in the olfactory system where rich spatio-temporal dynamics is observed during, and following, exposure to odours. It is now widely accepted that odour identity is represented in terms of stimulus-specific rate patterning observed in the c...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.07.032
更新日期：2012-01-24 00:00:00
abstract：:Slow field potentials (SFP) lasting up to 5 s followed penicillin-induced bursts in CA3 of guinea pig hippocampal slices and accounted for most of the interburst interval. The longest lasting component of the SFP which was maximal in the distal apical dendritic region was usually absent in s. pyramidale. Potassium flu...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90138-7
更新日期：1987-02-10 00:00:00
abstract：:The median preoptic nucleus (MnPN) of the hypothalamus contains sleep-active neurons including sleep-active GABAergic neurons and is involved in the regulation of nonREM/REM sleep. The hypocretinergic (HCRT) neurons of the perifornical-lateral hypothalamic area (PF-LHA) and serotonergic (5-HT) neurons of the dorsal ra...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2008.07.115
更新日期：2008-10-09 00:00:00
abstract：:This study examined whether phenidone, a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), affects the clinical symptoms of experimental autoimmune encephalomyelitis (EAE) in the rat, and the expression of both COX-1/-2 and 5-LOX in EAE spinal cords. Oral phenidone (200 mg/kg) significantly suppressed the...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.12.017
更新日期：2005-02-28 00:00:00
abstract：:Fetal mouse retinal ganglion cell axons have been shown to ramify within co-cultured basement membrane secreting tumor explants and upon isolated basement membranes. Here we report that laminin, a glycoprotein found in basement membranes and adhesion sites of a variety of cell types, acted as a substrate for retinal e...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(84)90184-6
更新日期：1984-01-01 00:00:00
abstract：:Saccadic adaptation is the progressive correction of systematic saccade targeting errors. When a saccade to a particular target is adapted, saccades within a spatial window around the target, the adaptation field, are affected as a function of their distance from the adapted target. Furthermore, previous studies sugge...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.07.040
更新日期：2007-10-03 00:00:00
abstract：:[1-14C]Octanoate (OCTO) is rapidly extracted from blood and metabolized by brain. Up to 6 min following an intravenous pulse injection the autoradiographic pattern of brain labeling reflects differences in blood flow and energy metabolism. When animals are given OCTO during visual or somatosensory stimulation the auto...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90486-x
更新日期：1985-06-03 00:00:00
abstract：:We describe a method to produce frog olfactory epithelium with a population of developmentally synchronized receptor cells suitable for electrophysiological studies. The epithelium is ablated with ZnSO4 and allowed to regenerate for 10 days. Generation of new cells is then blocked by continuous treatment with hydroxyu...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(87)90122-2
更新日期：1987-02-01 00:00:00
abstract：:Labyrinthine-intact guinea pigs received unilateral, brainstem cannula injections of (1) 2.5 micrograms of the selective dihydropyridine L-type Ca2+ channel agonist, Bay K 8644 (n = 4 animals); (2) 10 micrograms Bay K 8644 (n = 4); 12.5 micrograms of the selective dihydropyridine L-type Ca2+ channel antagonist, nifedi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90677-f
更新日期：1993-12-10 00:00:00
abstract：:Receptor subunit composition is believed to play a major role in the synaptic trafficking of AMPA receptors (AMPARs), and thus in activity-dependent synaptic plasticity. To isolate a physiological role of GluA1-containing AMPARs in area CA3 of the hippocampus, pair recordings were performed in organotypic hippocampal ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2011.11.029
更新日期：2012-01-30 00:00:00
abstract：:A potential mechanism for valproate (VPA)-induced increases in glial cell-substratum adhesivity has been demonstrated. Metabolically labelled glioma (C6) and primary astrocytes showed a statistically significant accumulation of protein when cultured in the presence of therapeutic concentrations of VPA (1 mM). This was...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90292-2
更新日期：1988-08-30 00:00:00
