Central dopamine agonist activity on the 8-alpha-amino-ergoline CU 32-085.

abstract：:In order to determine the origin of the catecholamine innervation of the rat piriform cortex (PC), we combined retrograde transport of the B subunit of the cholera toxin (CTb) with tyrosine hydroxylase (TH) immunohistochemistry. A substantial number of CTb retrogradely labeled cells was found in the parabrachial pigme...

journal_title：Brain research

authors： Datiche F,Cattarelli M

更新日期：1996-02-26 00:00:00

abstract：:Cajal-Retzius (CR) cells of the mammalian neocortex co-express the extracellular matrix protein Reelin and p73, a transcription factor involved in cell death and survival. Most neocortical CR cells derive from the cortical hem, with minor additional sources. We analyzed the distribution of Reelin and p73 immunoreactiv...

journal_title：Brain research

authors： Cabrera-Socorro A,Hernandez-Acosta NC,Gonzalez-Gomez M,Meyer G

更新日期：2007-02-09 00:00:00

abstract：:Noradrenergic and dopaminergic regulation of thyrotropin (TSH) secretion was investigated in adult male Wistar rats. TSH secretion displayed a circadian variation with peak serum TSH levels at 10.00 h. The alpha 2-adrenoceptor agonist, clonidine (250 micrograms/kg, i.p.), was found to cause an enhancement of serum TSH...

journal_title：Brain research

authors： Jaffer A,Russell VA,Taljaard JJ

更新日期：1987-02-24 00:00:00

abstract：:The CNP neuropeptides (Command Neuron Peptides) were first found in the command neurons for withdrawal behavior in the terrestrial snail. Given the fact that certain peptides can be found in various invertebrates, we examined Drosophila brains to determine if CNP-like peptides were present. Two types of antisera were ...

journal_title：Brain research

authors： Ierusalimsky VN,Balaban PM

更新日期：2007-06-04 00:00:00

abstract：:Corticosteroids exert important effects on brain function via glucocorticoid (GRs) and mineralocorticoid receptors (MRs) by inducing receptor translocation to the nucleus, where the receptor-ligand complexes modulate transcription of target genes. Based on studies describing uneven receptor expression patterns, region...

journal_title：Brain research

authors： Sarabdjitsingh RA,Meijer OC,Schaaf MJ,de Kloet ER

更新日期：2009-01-16 00:00:00

abstract：:Tetramethylpyrazine (TMP) is one of the alkaloids contained in Ligustrazine which has been used in traditional Chinese medicine as an analgesic for injury and dysmenorrhea. ATP can elicit the sensation of pain. This study observed the effects of TMP on ATP-activated current (IATP) in rat DRG neurons. TMP (0.1-1 mM) co...

journal_title：Brain research

authors： Liang SD,Xu CS,Zhou T,Liu HQ,Gao Y,Li GL

更新日期：2005-04-08 00:00:00

abstract：:The projections of serotonin-containing neurons of the midbrain raphe nuclei (nucleus raphe dorsalis, nucleus centralis superior) are studied by analysis of axonal transport of labeled amino acids. These results are correlated with regional alterations of serotonin content following midbrain raphe lesions which produc...

journal_title：Brain research

authors： Halaris AE,Jones BE,Moore RY

更新日期：1976-05-14 00:00:00

abstract：:Prepro-vasoactive intestinal peptide (prepro-VIP) is processed to at least three biologically active peptides: VIP, peptide histidine isoleucine (PHI) and an extended PHI, peptide histidine valine (PHV). The aim of the present investigation was by chromatography combined with RIA and immunocytochemistry to determine w...

journal_title：Brain research

authors： Mikkelsen JD,Fahrenkrug J

更新日期：1994-09-05 00:00:00

abstract：:Tourette syndrome (TS) is a childhood-onset tic disorder associated with abnormal development of brain networks involved in the sensory and motor processing. An involvement of immune mechanisms in its pathophysiology has been proposed. Animal models based on active immunization with bacterial or viral mimics, direct i...

journal_title：Brain research

authors： Martino D,Zis P,Buttiglione M

更新日期：2015-08-18 00:00:00

abstract：:Primary open angle glaucoma (POAG) is a leading cause of irreversible blindness worldwide. Previous MRI studies have revealed that POAG can be associated with alterations in hippocampal function. Thus, the aim of this study was to investigate a relationship between chronic high intraocular pressure (IOP) and hippocamp...

journal_title：Brain research

authors： Yuan Y,Chen Z,Li L,Li X,Xia Q,Zhang H,Duan Q,Zhao Y

更新日期：2017-11-15 00:00:00

abstract：:Transgenic mice expressing human APPswe and PS1-A264E mutations mimic certain neuropathological features of Alzheimer's disease (AD). These mice have elevated levels of the highly fibrillogenic amyloid beta1-42 peptide (Abeta42) and develop amyloid plaques around the age of 9 months. Our aim was to find whether these ...

journal_title：Brain research

authors： Wang J,Ikonen S,Gurevicius K,van Groen T,Tanila H

更新日期：2002-07-12 00:00:00

abstract：:Intoxication with organophosphorus (0P) anticholinesterase agents such as soman triggers irreversible lesions in some cerebral areas. Administration of soman at the LD 50 leads to an increased activity of NADPH-diaphorase (= NO-synthase) in the cerebral endothelial cells from the 6th hour after poisoning. This activit...

journal_title：Brain research

authors： Bouchaud C,Chollat-Namy A,Duserre S,Delamanche IS

更新日期：1994-10-17 00:00:00

abstract：:High cell density, with attendant aggregation, selectively increases expression of substance P (SP) and choline acetyltransferase (ChAT) in virtually pure neonatal sympathetic neuronal cultures. To investigate the specific role of cell contact in selective transmitter expression, SP content and ChAT activity were exam...

journal_title：Brain research

authors： Adler JE,Black IB

更新日期：1986-12-01 00:00:00

abstract：:The activity of choline kinase (CK) was examined in the rat superior cervical ganglion (SCG) during development and following postganglionic axotomy. The highest specific enzyme activity (nmol phosphorylcholine/mg protein/h) 52 +/- 8, is observed 5 d before birth, then it rapidly decreases by about 50%, reaching at th...

journal_title：Brain research

authors： Gilad GM,Gilad VH

更新日期：1981-09-14 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH) prevents the development of drug- or stress-induced hyperglycemia in mice through action at central sites. To study the role of the pituitary in mediating this action, we have evaluated the effect of TRH analogs lacking hypophysiotropic activity, acid-TRH and DN 1417, in blocking gl...

journal_title：Brain research

authors： Amir S

更新日期：1988-07-05 00:00:00

abstract：:The dmy rat is an autosomal recessive mutant that exhibits severe myelin destruction throughout the white matter of the central nervous system. Recently, a point mutation in intron 3 of the Mrs2 has been found in the dmy rat. Mrs2 encodes an essential component of the major electrophoretic Mg(2+) influx system in mito...

journal_title：Brain research

authors： Kuwamura M,Inumaki K,Tanaka M,Shirai M,Izawa T,Yamate J,Franklin RJ,Kuramoto T,Serikawa T

更新日期：2011-05-10 00:00:00

abstract：:Androgens are involved in a variety of centrally mediated functions after binding to their intracellular receptors. In the present report, we have employed the androgen receptor antibody, PG-21, and indirect immunohistochemistry to examine the distribution of cells containing androgen receptor-like immunoreactivity (A...

journal_title：Brain research

authors： Iqbal J,Swanson JJ,Prins GS,Jacobson CD

更新日期：1995-12-12 00:00:00

abstract：:The actions of pentobarbital (PB) and diphenylhydantoin (DPH) have been studied on neurons of dorsal root ganglia from adult rats. At anesthetic level (i.e. 1--2 x 10(-4) M), PB greatly enhanced neuronal responses to gamma-aminobutyric acid (GABA); at 10(-3) M PB caused a small depolarization and profoundly attenuated...

journal_title：Brain research

authors： Connors BW

更新日期：1981-03-02 00:00:00

abstract：:The L-isomer of beta-N-methylamino-L-alanine (BMAA), present in free form in seed of Cycas circinalis, elicits in spinal cord cultures a pattern of acute postsynaptic neuronal vacuolation comparable to that induced by beta-N-oxalylamino-L-alanine (BOAA), an excitotoxic amino acid of greater potency isolated from seed ...

journal_title：Brain research

authors： Nunn PB,Seelig M,Zagoren JC,Spencer PS

更新日期：1987-05-05 00:00:00

abstract：:We studied the short- and long-term epileptogenic effects of massed stimulation (MS) of the piriform cortex. Sprague-Dawley rats with electrodes implanted bilaterally in the anterior piriform cortex and the dorsal and ventral hippocampi underwent MS: electrical stimulation of the left piriform cortex every 5 min for 6...

journal_title：Brain research

authors： Timofeeva OA,Peterson GM

更新日期：1997-04-18 00:00:00

abstract：:Somatosensory evoked potentials (SEPs) elicited by right posterior tibial nerve stimulation were simultaneously recorded from 21-27 epidural electrodes in three monkeys. N23-P40 was recorded anterior to the left central sulcus, and P23-N40 was recorded on the parietal midline and the middle portion of the right hemisp...

journal_title：Brain research

authors： Hayashi N,Nishijo H,Endo S,Ono T

更新日期：1997-11-07 00:00:00

abstract：:Fetal exposure to dexamethasone (DEX) alters brain plasticity and cognitive functions during adulthood in a sex-dependent manner. The mechanisms underlying such long-lasting sex-dependent change of prenatal DEX is not well understood. The p73 gene plays an important role in brain development. It encodes for two protei...

journal_title：Brain research

authors： Abul M,Al-Bader MD,Mouihate A

更新日期：2019-03-15 00:00:00

abstract：:Microinfusions of the benzodiazepine anxiolytic midazolam into the central or basolateral amygdaloid nuclei produced different anxiolytic effects in two tests of rat 'anxiety'. Infusions into the basolateral nucleus impaired open-arm avoidance in the elevated plus-maze test, but did not impair shock-probe avoidance in...

journal_title：Brain research

authors： Pesold C,Treit D

更新日期：1995-02-13 00:00:00

abstract：:The effect of suprachiasmatic nucleus (SCN) ablation on rhythms in brain neurotransmitter receptors was studied. In control animals, the rhythms in the number of alpha-adrenergic and benzodiazepine receptors were circadian, whereas the rhythms in beta-adrenergic and acetylcholine receptors were ultradian. SCN ablation...

journal_title：Brain research

authors： Kafka MS,Marangos PJ,Moore RY

更新日期：1985-02-18 00:00:00

abstract：:Albino rats received 10 s of sub-seizure electrical stimulation applied to the dentate gyrus granule cells immediately after acquisition of information on trial 1 of a 2-trial radial maze spatial memory task. Granule cell stimulation selectively reduced the probability of accessing information held in declarative memo...

journal_title：Brain research

authors： Collier TJ,Routtenberg A

更新日期：1984-09-24 00:00:00

abstract：:Double impregnation staining of tissue was used to study on thick sections the three-dimensional configuration of the peripheral endoplasmic reticulum in neurosecretory neurons of the supraoptic nucleus in control and water-deprived rats. According to the spatial organization of the endoplasmic reticulum, two types of...

journal_title：Brain research

authors： Alonso G,Assenmacher I

更新日期：1979-07-13 00:00:00

abstract：:The active and passive membrane properties of developing Purkinje neurons in control cultures and cultures chronically treated with 20 or 40 mM ethanol for 1 or 2 weeks were examined using whole-cell current-clamp techniques. The membrane properties were characterized by the features of the voltage responses evoked by...

journal_title：Brain research

authors： Gruol DL

更新日期：1991-08-30 00:00:00

abstract：:We have shown previously that plasmin facilitated the generation of long-term potentiation (LTP) in CA1 and dentate region of rat hippocampus. In the present study, we investigated the effects of plasmin on postsynaptic currents in CA1 pyramidal neurons of rat hippocampal slices. Plasmin (100 nM) had no effect on NMDA...

journal_title：Brain research

authors： Mizutani A,Tanaka T,Saito H,Matsuki N

更新日期：1997-06-27 00:00:00

abstract：BACKGROUND:Sex-specific trajectories in white matter development during adolescence may help explain cognitive and behavioral divergences between males and females. Knowledge of sex differences in typically developing adolescents can provide a basis for interpreting sexual dimorphisms in abilities and actions. METHOD:...

journal_title：Brain research

authors： Bava S,Boucquey V,Goldenberg D,Thayer RE,Ward M,Jacobus J,Tapert SF

更新日期：2011-02-23 00:00:00

abstract：:The distribution of pituitary adenylate cyclase-activating polypeptide (PACAP) was examined in the tooth pulp. In rat and human tooth pulps, PACAP-immunoreactive (IR) nerve fibers were observed around blood vessels and in the subodontoblastic and odontoblastic layers. The predentine and dentine were devoid of such ner...

journal_title：Brain research

authors： Ichikawa H,Sugimoto T

更新日期：2003-08-08 00:00:00