Suprachiasmatic nucleus ablation abolishes circadian rhythms in rat brain neurotransmitter receptors.

abstract：BACKGROUND:Toll-like receptor 4 (TLR4) is an important mediator of the innate immune response. It significantly contributes to neuroinflammation and may be involved in ischemic tolerance. It is unknown how cerebral ischemia in the cortex and postconditioning might affect inflammatory reactions in the hippocampus or whe...

journal_title：Brain research

authors： Feng R,Li S,Li F

更新日期：2011-04-12 00:00:00

abstract：:We investigated the protective effect of subchronic treatment of the A2A receptor antagonist, SCH 58261 (0.01 mg/kg, i.p.), administered 5 min, 6 h and 15 h after permanent right middle cerebral artery occlusion (MCAo). Twenty-four hours after ischemia, an extensive pallid area, evaluated by cresyl violet staining, is...

journal_title：Brain research

authors： Melani A,Gianfriddo M,Vannucchi MG,Cipriani S,Baraldi PG,Giovannini MG,Pedata F

更新日期：2006-02-16 00:00:00

abstract：:Following cholinergic denervation of the hippocampus by medial septal lesions, and unusual neuronal reorganization occurs, in which peripheral sympathetic fibers, originating from the superior cervical ganglia, grow into the hippocampus. Previously, we have found that both hippocampal sympathetic ingrowth (HSI) and ch...

journal_title：Brain research

authors： Harrell LE,Kolasa K,Parsons DS,Ayyagari V

更新日期：1995-04-10 00:00:00

abstract：:The petrosal ganglia contain the somata of the sensory fibers of the glossopharyngeal nerves, innervating structures of the tongue, pharynx, carotid sinus and carotid body. Petrosal ganglia were excised from adult cats and their neurons were dissociated and kept in tissue culture for 7-12 days. Intracellular recording...

journal_title：Brain research

authors： Varas R,Alcayaga J,Zapata P

更新日期：2000-11-03 00:00:00

abstract：:Central catecholaminergic nerves have been shown to participate in the integration of cardio-cardiac reflexes induced by coronary artery ligation in the rat. In this study we measured the turnover of dopamine, norepinephrine and epinephrine in microdissected brain regions to identify some of the specific neural loci i...

journal_title：Brain research

authors： Sole MJ,Hussain MN,Versteeg DH,de Kloet ER,Adams D,Lixfeld W

更新日期：1982-03-11 00:00:00

abstract：:Previous studies suggest that brainstem catecholamine (CA) fibers which mediate amphetamine (AMPH)-induced anorexia ascend through the midlateral medical forebrain bundle and perifornical region and terminate in the perifornical hypothalamic region (PFH) at the level of the hypothalamic ventromedial nucleus. Through s...

journal_title：Brain research

authors： McCabe JT,Leibowitz SF

更新日期：1984-10-08 00:00:00

abstract：:In situ hybridization (ISH) is an essential technique for mapping gene expression in the brain. Although many ISH protocols provide for quantitative analysis of individual mRNAs in different brain regions or across experimental conditions, this technique has lacked the necessary standardization for quantitative compar...

journal_title：Brain research

authors： Broide RS,Trembleau A,Ellison JA,Cooper J,Lo D,Young WG,Morrison JH,Bloom FE

更新日期：2004-03-12 00:00:00

abstract：:The production and localization of cell-associated forms of beta-amyloid precursor protein (APP) of Alzheimer's disease was investigated in primary cultures of mouse glial cells. In both oligodendrocytes and astrocytes, immunofluorescence staining with an antibody against the carboxy terminus of APP revealed an intens...

journal_title：Brain research

authors： Mizuguchi M,Ikeda K,Kim SU

更新日期：1992-07-03 00:00:00

abstract：:Amnestic type mild cognitive impairment (aMCI) refers to a transitional stage between normal aging and Alzheimer's disease (AD). Whilst posterior cingulate cortex (PCC) is believed to have a key role in a default network and be involved in the pathophysiology of AD, few studies have investigated whole-brain functional...

journal_title：Brain research

authors： Bai F,Watson DR,Yu H,Shi Y,Yuan Y,Zhang Z

更新日期：2009-12-11 00:00:00

abstract：:Chronic intermittent hypoxia (CIH) may cause sustained systemic hypertension by increasing sympathetic neural discharge (SND). We hypothesized that CIH alters brainstem circuits modulating SND. After 30 days of CIH exposure in rats, increased c-fos labeling was seen in the nucleus of the solitary tract and ventrolater...

journal_title：Brain research

authors： Greenberg HE,Sica AL,Scharf SM,Ruggiero DA

更新日期：1999-01-23 00:00:00

abstract：:The disturbance of microcirculation following cerebral ischemia leads to an enlargement of cerebral infarct volume. Endogenous thrombin may play a role in this disturbance of microcirculation following cerebral ischemia. Therefore, the inhibition of thrombin may improve neurodegeneration and the accumulation of cerebr...

journal_title：Brain research

authors： Ohyama H,Hosomi N,Takahashi T,Mizushige K,Kohno M

更新日期：2001-06-01 00:00:00

abstract：:Changes in GABA(A) receptor alpha(1) subunit gene expression occur in the globus pallidus and substantia nigra pars reticulata following lesions of the nigrostriatal tract. To determine whether these changes are translated at the protein level, we performed quantitative autoradiography with the alpha(1) selective liga...

journal_title：Brain research

authors： Chadha A,Howell O,Atack JR,Sur C,Duty S

更新日期：2000-04-17 00:00:00

abstract：:The enzymes catalyzing the breakdown of TRH are soluble and dependent upon active sulfhydryl groups. One of these enzymes is a pyroglutamyl aminopeptidase (EC 3.4.11.8) (apparent molecular weight 60,000 daltons) with a specificity restricted to pyroglutamyl peptide bonds. The second enzyme is a prolyl endopeptidase (a...

journal_title：Brain research

authors： Busby WH Jr,Youngblood WW,Kizer JS

更新日期：1982-06-24 00:00:00

abstract：:Light microscopic double labeling immunocytochemistry for vasoactive intestinal peptide (VIP) and gonadotrophin-releasing hormone (GnRH) was carried out on the hypothalami of male and female rats. It was found that the number of VIP boutons that terminate on GnRH neurons and the percentage of GnRH neurons contacted by...

journal_title：Brain research

authors： Horvath TL,Cela V,van der Beek EM

更新日期：1998-06-08 00:00:00

abstract：:Cortical Spreading Depression (CSD) is a well-studied model of preconditioning that provides a high degree of tolerance to a subsequent ischemic event in the brain. The present study was undertaken in order to determine whether the release of ATP during CSD could contribute to the induction of ischemic tolerance. Dire...

journal_title：Brain research

authors： Schock SC,Munyao N,Yakubchyk Y,Sabourin LA,Hakim AM,Ventureyra EC,Thompson CS

更新日期：2007-09-07 00:00:00

abstract：:Cholecystokinins in rat cerebral cortex were studied by radioimmunoassay using an antiserum specific for the COOH-terminus of CCK8. Total concentrations of immunoreactive CCK in cortex were 3-4 fold higher than in jejunum. Rat cerebral CCK was purified by immuno-affinity adsorption to the IgG fraction of CCK antisera ...

journal_title：Brain research

authors： Dockray GJ

更新日期：1980-04-21 00:00:00

abstract：:The location and nature of the changes underlying long-term potentiation (LTP) remain controversial issues. In this study, we tested the possibility that changes in binding properties of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionate (AMPA/quisqualate and N-methyl-D-aspartate (NMDA) subtype of glutamate rec...

journal_title：Brain research

authors： Tocco G,Maren S,Shors TJ,Baudry M,Thompson RF

更新日期：1992-02-28 00:00:00

abstract：:The present study investigated the antidepressant potential of curcumin in olfactory bulbectomy and forced swimming test models of depression in male albino rats under chronic treatment. The experimental animals were divided into four groups, and curcumin was administered for 45 days. Our results showed that the curcu...

journal_title：Brain research

authors： Chang XR,Wang L,Li J,Wu DS

更新日期：2016-07-01 00:00:00

abstract：:Mutations in two genes, alpha-synuclein and parkin, have been identified as some rare causes for familial Parkinson's disease (PD). alpha-Synuclein and parkin protein have subsequently been identified in Lewy bodies (LB). To gain further insight into the pathogenesis of PD we investigated the role of neurofilament lig...

journal_title：Brain research

authors： Rahner N,Holzmann C,Krüger R,Schöls L,Berger K,Riess O

更新日期：2002-09-27 00:00:00

abstract：:Fos-like immunoreactivity (FLI) can indicate the location of neurons activated following expression of conditioned taste aversion (CTA). After one conditioning trial FLI has been identified in the intermediate nucleus of the solitary tract (iNTS) with little expression in other brain regions. The present study assesse...

journal_title：Brain research

authors： Navarro M,Spray KJ,Cubero I,Thiele TE,Bernstein IL

更新日期：2000-12-29 00:00:00

abstract：:Depolarizing actions of 4 conformationally restricted L-glutamate analogues, (2S,3S,4S) isomer (L-CCG-I), (2S,3R,4R) isomer (L-CCG-II), (2S,3S,4R) isomer (L-CCG-III) and (2S,3R,4S) isomer (L-CCG-IV) of L-alpha-(carboxycyclopropyl)-glycine (L-CCG), were investigated in the isolated rat spinal cord by extracellular reco...

journal_title：Brain research

authors： Shinozaki H,Ishida M,Shimamoto K,Ohfune Y

更新日期：1989-02-20 00:00:00

abstract：:Recently, this laboratory provided evidence that interleukin-1beta (IL-1beta), an immune and brain-derived cytokine, microinjected into the medial hypothalamus, potentiates defensive rage behavior in the cat elicited from the midbrain periaqueductal gray (PAG), and that such effects are blocked by a 5-HT2 receptor ant...

journal_title：Brain research

authors： Hassanain M,Bhatt S,Zalcman S,Siegel A

更新日期：2005-06-28 00:00:00

abstract：:Recent neurocognitive studies of visual word recognition provide information about neuronal networks correlated with processes involved in lexical access and their time course (e.g., [Holcomb, Ph.J., Grainger J. and O'Rourke, T. (2002). An Electrophysiological Study of the Effects of Orthographic Neighborhood Size on ...

journal_title：Brain research

authors： Braun M,Jacobs AM,Hahne A,Ricker B,Hofmann M,Hutzler F

更新日期：2006-02-16 00:00:00

abstract：:The effects of adenosine and the adenosine binding enhancer, PD 81,723, on low magnesium-induced bursting in the in vitro hippocampal slice were examined. Extracellular recordings were obtained from the CA3 pyramidal cell layer while electrically stimulating in the stratum radiatum under low magnesium perfusion. Adeno...

journal_title：Brain research

authors： Janusz CA,Berman RF

更新日期：1993-08-13 00:00:00

abstract：:The purpose of this study was to investigate autofluorescent pigment granules (lipofuscin, ceroid) in the trigeminal neurons (TN) during aging and streptozotocin-induced diabetes. Four young adult male rats were injected with streptozotocin (STZ; 50 mg/kg) to produce diabetes (DM), for comparison with four young uninj...

journal_title：Brain research

authors： Sugaya A,Sugimioto H,Mogi N,Tsujigami H,Deguchi S

更新日期：2004-02-27 00:00:00

abstract：:To determine whether the sympathoexcitatory projection from the rostral ventrolateral medulla (RVL) to the sympathetic intermediolateral nucleus (IML) of the spinal cord might use glutamate as an excitatory transmitter, we performed a dual-label, transport and immunocytochemical ultrastructural study. Axon terminals w...

journal_title：Brain research

authors： Morrison SF,Callaway J,Milner TA,Reis DJ

更新日期：1991-10-18 00:00:00

abstract：:Trisomy 21 (Down syndrome) results in abnormalities in electrical membrane properties of cultured human fetal dorsal root ganglion (DRG) neurons. Action potentials have faster rates of depolarization and repolarization, with decreased spike duration, compared to diploid neurons. In order to analyze the faster depolari...

journal_title：Brain research

authors： Caviedes P,Ault B,Rapoport SI

更新日期：1990-03-05 00:00:00

abstract：:One model useful for demonstrating axonal regeneration in the central nervous system is that in which peripheral tissue, particularly the iris, is implanted into the brain or spinal cord. The aim of the present study was to establish the origin of some of the regenerating fibers by the use of an autoradiograhic tracin...

journal_title：Brain research

authors： Schonfeld AR,Katzman R

更新日期：1980-09-22 00:00:00

abstract：:We tested the hypothesis that intravenous infusion of human marrow stromal cells (hMSC) with a nitric oxide donor, (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl) aminio] diazen-1-ium-1,2-diolate (DETA/NONOate), enhances angiogenesis, neurogenesis and neurological functional recovery after stroke in rats compared to indivi...

journal_title：Brain research

authors： Chen J,Li Y,Zhang R,Katakowski M,Gautam SC,Xu Y,Lu M,Zhang Z,Chopp M

更新日期：2004-04-16 00:00:00

abstract：:It is well known that locus coeruleus (LC) of the rat shows intense mu-opioid receptor-like immunoreactivity (MOR-LI). In the course of our study on the distribution of MOR-LI in the brain of the Japanese monkey (Macaca fuscata), however, no MOR-LI was found in the LC although the distribution pattern of MOR-LI in oth...

journal_title：Brain research

authors： Chen J,Koyama N,Kaneko T,Mizuno N

更新日期：1997-05-02 00:00:00