Changes in [3H]zolpidem and [3H]Ro 15-1788 binding in rat globus pallidus and substantia nigra pars reticulata following a nigrostriatal tract lesion.

abstract：:This neuroimaging study investigated the neural mechanisms of the effect of conversation on visual event detection during a driving-like scenario. The static load paradigm, established as predictive of visual reaction time in on-road driving, measured reaction times to visual events while subjects watched a real-world...

journal_title：Brain research

authors： Hsieh L,Young RA,Bowyer SM,Moran JE,Genik RJ 2nd,Green CC,Chiang YR,Yu YJ,Liao CC,Seaman S

更新日期：2009-01-28 00:00:00

abstract：:Brain levels of tyrosine, dopamine (DA), noradrenaline (NA), tryptophan, 5-hydroxytryptamine (5-HT), and 5-hydroxyindoleacetic acid (5-HIAA) were measured after 30, 60 and 120 min of sustained seizure activity, induced in paralyzed, artificially ventilated and anaesthetized (70% N2O) rats by administration of bicucull...

journal_title：Brain research

authors： Calderini G,Carlsson A,Nordström CH

更新日期：1978-11-24 00:00:00

abstract：:An isoindolin-1-one derivate, JM-1232(-), was recently developed as a sedative and hypnotic agent with a strong affinity for the central benzodiazepine binding site of gamma-aminobutyric acid(A) (GABA(A)) receptors. The purpose of this study was to examine the effects of JM-1232(-) on the cardiovascular and sympatheti...

journal_title：Brain research

authors： Shirasaka T,Kunitake T,Tsuneyoshi I

更新日期：2009-12-01 00:00:00

abstract：:We used whole-head magnetoencephalograpy (MEG) to record changes in neuromagnetic N100m responses generated in the left and right auditory cortex as a function of the match between visual and auditory speech signals. Stimuli were auditory-only (AO) and auditory-visual (AV) presentations of /pi/, /ti/ and /vi/. Three t...

journal_title：Brain research

authors： Davis C,Kislyuk D,Kim J,Sams M

更新日期：2008-11-25 00:00:00

abstract：:In the present study, we assessed the beneficial synergistic effects of concurrent treatment with low doses of cilostazol and probucol against focal cerebral ischemic infarct in rats. The ischemic infarct induced by 2-h occlusion of middle cerebral artery (MCA) and 22-h reperfusion was significantly reduced in rat bra...

journal_title：Brain research

authors： Park SY,Lee JH,Kim CD,Rhim BY,Hong KW,Lee WS

更新日期：2007-07-09 00:00:00

abstract：:Plectin is associated with intermediate filaments, such as glial fibrillary acidic protein (GFAP) and vimentin, which have an important role in the glial reactions after lesions. The present study investigates the plectin immunoreactivity following stab wounds in the cortex and the underlying white matter of adult rat...

journal_title：Brain research

authors： Kálmán M,Szabó A

更新日期：2000-02-28 00:00:00

abstract：:In this research, we investigated striatal neurogenesis in 3-, 6-, 12-, and 18-month-old rats after cerebral ischemic injury. All rats were subjected to a 20-min middle cerebral artery occlusion (MCAO), given 5'-bromodeoxyuridine (BrdU, 30 mg/kg, i.p.) once daily during days 4-7 and sacrificed 2 weeks after MCAO. Neur...

journal_title：Brain research

authors： Chen Y,Sun FY

更新日期：2007-08-29 00:00:00

abstract：:Hippocampal neurogenesis plays a very important role in learning and memory functions. In a search for best neurological drugs that protect neuronal cells and stimulate neurogenesis with no side effects, cannabinoids proved to be a strong group of substances having many beneficial properties. The aim of this study was...

journal_title：Brain research

authors： Andres-Mach M,Haratym-Maj A,Zagaja M,Rola R,Maj M,Chrościńska-Krawczyk M,Luszczki JJ

更新日期：2015-10-22 00:00:00

abstract：:Isolated brain capillary endothelial cells contain high activity levels of the blood-brain barrier (BBB) marker enzymes gamma-glutamyltranspeptidase (gamma-GT) and alkaline phosphatase (ALP). In primary culture the activities of these specific enzymes decrease with increasing cell proliferation to a constant low value...

journal_title：Brain research

authors： Meyer J,Mischeck U,Veyhl M,Henzel K,Galla HJ

更新日期：1990-04-30 00:00:00

abstract：:The present study was undertaken to disclose temporal changes in the distribution of Fos-like immunoreactive (-IR) neurons in the trigeminal subnucleus caudalis (SpVc), one of the important relay nuclei for processing the nociceptive information from the oro-facial regions, following induction of experimental tooth mo...

journal_title：Brain research

authors： Aihara Y,Maeda T,Hanada K,Wakisaka S

更新日期：1999-02-20 00:00:00

abstract：:Recent studies suggest that apolipoprotein E (apoE) might play a neurotrophic function in the central nervous system and that altered functioning of this molecule could result in neurodegeneration. The main objective of this study was to determine if neurodegenerative and cognitive alterations in apoE-deficient mice a...

journal_title：Brain research

authors： Masliah E,Samuel W,Veinbergs I,Mallory M,Mante M,Saitoh T

更新日期：1997-03-21 00:00:00

abstract：:The behaviour and cognitive abilities of marmosets with bilateral ablations of either the archicortex on the mediodorsal surface or the paleocortex on the ventrolateral surface of the frontal lobes were assessed in terms of the types of information being handled, the mode of action (inhibitory versus productive mechan...

journal_title：Brain research

authors： Ridley RM,Durnford LJ,Baker JA,Baker HF

更新日期：1993-11-19 00:00:00

abstract：:Anterograde and retrograde tracing experiments employing WGA-HRP were used to identify an auditory projection area within the frontal telencephalon of the pigeon. The projection originates in a nucleus of the lateral lemniscus, travels with the quintofrontal tract and terminates within nucleus basalis. The location of...

journal_title：Brain research

authors： Arends JJ,Zeigler HP

更新日期：1986-11-29 00:00:00

abstract：:We evaluated the effects of glycine exposure upon CA1-evoked response in the rat hippocampal slice. Exposure to 10 mM glycine for 16 min produced rapid neuronal firing and increased orthodromic population spike (PS), followed by loss of CA1 neural transmission. Upon recovery, CA1 orthodromic and antidromic PS regained...

journal_title：Brain research

authors： Wallis RA,Panizzon KL,Nolan JP

更新日期：1994-11-21 00:00:00

abstract：:At a physiologically relevant concentration (1.25 microM), aluminum had an activating effect on oligodendrocyte cell cultures, similar to that previously reported for other cell types. G protein-linked signal transduction was stimulated as indicated by enhanced production of IP3, and protein synthesis was increased. A...

journal_title：Brain research

authors： Golub MS,Zhang W,Keen CL,Goldkorn T

更新日期：2002-06-21 00:00:00

abstract：:Prostaglandins are now thought to play an important role in nociceptive information transmission in the spinal cord. Prostaglandins are known to be produced by cyclooxygenase (COX), which catalyzes the conversion of arachidonic acid. Two forms of COX have been identified: COX-1, which is constitutively expressed in mo...

journal_title：Brain research

authors： Yamamoto T,Nozaki-Taguchi N

更新日期：1996-11-11 00:00:00

abstract：:The dorsolateral quadrant of the lateral septal nucleus receives projections from both the ipsilateral and the contralateral fimbria. In the adult rat the effect of fimbrial lesions on synapse formation has been studied by a quantitative electron microscopic analysis of the various types of synapses present, using ele...

journal_title：Brain research

authors： Field PM,Coldham DE,Raisman G

更新日期：1980-05-05 00:00:00

abstract：:Retinotectal projections were studied in 33 different species of Actinopterygii, the ray-finned fishes, with horseradish peroxidase and cobalt tracing techniques. The distribution of retinorecipient layers in the contralateral optic tectum was analyzed. In addition, the degree of differentiation of the stratum periven...

journal_title：Brain research

authors： von Bartheld CS,Meyer DL

更新日期：1987-09-15 00:00:00

abstract：:Stanniocalcin (STC-1), a 50 kDa glycoprotein hormone that regulates calcium/phosphate homeostasis in bony fish and mammals, has been shown to be expressed in central neurons and choroid plexus, and to exert a protective effect against hypercalcemic and hypoxic damage to neurons. Circumventricular organs are known to f...

journal_title：Brain research

authors： Ratkovic S,Wagner GF,Ciriello J

更新日期：2008-07-07 00:00:00

abstract：:Reduced neuronal plasticity in the striatum, hippocampus, and neocortex is a common feature of transgenic mouse models of Huntington's disease (HD). Doublecortin (DCX) and polysialylated neural cell adhesion molecule (PSA-NCAM) are associated with structural plasticity in the adult mammalian brain, are markers of newl...

journal_title：Brain research

authors： Lazic SE,Goodman AO,Grote HE,Blakemore C,Morton AJ,Hannan AJ,van Dellen A,Barker RA

更新日期：2007-06-02 00:00:00

abstract：:Peripheral axotomy in neonatal rats induces neuronal death. We studied the anti-apoptotic protein Bcl-2 and cell death promoter Bax in spinal cord of neonatal rats after sciatic transection and treatment with melatonin, a neuroprotective substance. Pups were unilaterally axotomized at P2 and received melatonin (1 mg/k...

journal_title：Brain research

authors： Rogério F,Jordão H Jr,Vieira AS,Maria CC,Santos de Rezende AC,Pereira GA,Langone F

更新日期：2006-09-27 00:00:00

abstract：:Neurotrophins play a crucial role in the regulation of survival and the maintenance of specific functions for various populations of neurons. Neurotrophin-4 (NT-4) is most abundant in skeletal muscle, and is thought to promote sciatic nerve sprouting, inhibit agrin-induced acetylcholine receptor (AChR) clustering, evo...

journal_title：Brain research

authors： Sakuma K,Watanabe K,Sano M,Uramoto I,Nakano H,Li YJ,Kaneda S,Sorimachi Y,Yoshimoto K,Yasuhara M,Totsuka T

更新日期：2001-07-13 00:00:00

abstract：:The enduring effects of postweaning subchronic methylphenidate (MP) treatment and/or previous early preweaning methamphetamine (MA) application on dopamine (DA) fiber density were investigated in multiple cortical and subcortical areas of the gerbil brain. The study aimed to explore three questions: (1) is the develop...

journal_title：Brain research

authors： Grund T,Teuchert-Noodt G,Busche A,Neddens J,Brummelte S,Moll GH,Dawirs RR

更新日期：2007-10-24 00:00:00

abstract：:Reverse transcription-polymerase chain reaction demonstrated the expression of heme oxygenase-1 and heme oxygenase-2 (HO-2) mRNA in the cochlea, but the former was considered to be much lower than the latter. The HO-2-like immunoreactivity was observed mainly in supporting cells in the organ of Corti and in the spiral...

journal_title：Brain research

authors： Watanabe K,Oshima T,Kobayashi T,Ikeda K

更新日期：2003-03-14 00:00:00

abstract：:By using enkephalin immunohistochemistry combined with retrograde fluorescent labelling, a great majority of neurons in the rat cerebellum sending their axons to the spinal cord were shown to contain enkephalin immunoreactivity. These neurons were numerous and clustered in the fastigial nucleus but far less abundant i...

journal_title：Brain research

authors： Ikeda M,Houtani T,Nakagawa H,Baba K,Kondoh A,Ueyama T,Yamamoto T,Gemba H,Sugimoto T

更新日期：1995-09-04 00:00:00

abstract：:Thalamocortical connections were studied after injections of retrograde tracers were made into rostral or caudal parts of cortical area Fr2 in adult rats. The data reveal that both rostral Fr2 (rFr2) and caudal Fr2 (cFr2) receive input from the centrolateral, central medial, interanteromedial, mediodorsal, paracentral...

journal_title：Brain research

authors： Hicks RR,Huerta MF

更新日期：1991-12-24 00:00:00

abstract：:The sites of action of lidocaine on the responses evoked by stimulation of lateral column (LC) and dorsal root (DR) were studied in the isolated, intra-arterially perfused spinal cord of the bullfrog. When the ventral root volley produced by stimulation was abolished by lidocaine, the presynaptic focal potential was a...

journal_title：Brain research

authors： Kuno M,Matsuura S

更新日期：1982-10-07 00:00:00

abstract：:To examine the structural interactions between synaptically connected neurons in Aplysia, we have developed a method for simultaneously labeling two identified cell with different and compatible intraneuronal marking agents (horseradish peroxidase and [3H]N-acetyl-D-galactosamine) visible in both the light and electro...

journal_title：Brain research

authors： Thompson EB,Bailey CH

更新日期：1979-09-14 00:00:00

abstract：:As a means of probing the chemotransducer, impulse sequences from in vitro, superfused sinus nerve-carotid body preparations were analyzed for departures from randomness. Twelve of 17 spike trains showed interval histograms that did not differ significantly from exponential. Thus these sequences resembled a Poisson (r...

journal_title：Brain research

authors： Nolan WF,Donnelly DF,Smith EJ,Dutton RE

更新日期：1984-01-30 00:00:00

abstract：:The expressions of mRNAs encoding G protein alpha subunits were analyzed in the cerebral cortex of amygdaloid kindled rats. A remarkable increase in Gsalpha mRNA were observed on the bilateral cerebral cortex at 24 h after the last generalized seizure and persisted 3 weeks on the unstimulated side. Gi2alpha mRNA level...

journal_title：Brain research

authors： Iwasa H,Kikuchi S,Miyagishima H,Mine S,Koseki K,Hasegawa S

更新日期：1999-02-13 00:00:00