The adenosine binding enhancer, PD 81,723, inhibits epileptiform bursting in the hippocampal brain slice.

abstract：:The purpose of the present study was to examine the effects of N-methyl-D-aspartate (NMDA) receptor blockade on the activity of tuberoinfundibular dopaminergic (TIDA) neurons in male and female rats. TIDA neuronal activity was estimated by measuring either the accumulation of 3,4-dihydroxyphenylalanine (DOPA) 30 min a...

journal_title：Brain research

authors： Wagner EJ,Moore KE,Lookingland KJ

更新日期：1993-05-14 00:00:00

abstract：:The purpose of this study is to reveal whether the application of immunohistochemical examinations to the peripheral nervous system (PNS) can be a reliable method for the quantitative analysis of the blood-nerve barrier (BNB) and the relationship between restoration of BNB and nerve regeneration. Sciatic nerves in rat...

journal_title：Brain research

authors： Omura K,Ohbayashi M,Sano M,Omura T,Hasegawa T,Nagano A

更新日期：2004-03-19 00:00:00

abstract：:In order to investigate whether a fibrin-fibronectin-containing matrix of a peripheral regeneration chamber could promote the growth of central nervous system neurons, hippocampal and septal slices were co-cultured in the presence of this acellular substrate. In introducing the peripheral matrix into a 2-mm-long tube ...

journal_title：Brain research

authors： Knoops B,Hubert I,Hauw JJ,van den Bosch de Aguilar P

更新日期：1991-02-01 00:00:00

abstract：:Recent studies suggest that apolipoprotein E (apoE) might play a neurotrophic function in the central nervous system and that altered functioning of this molecule could result in neurodegeneration. The main objective of this study was to determine if neurodegenerative and cognitive alterations in apoE-deficient mice a...

journal_title：Brain research

authors： Masliah E,Samuel W,Veinbergs I,Mallory M,Mante M,Saitoh T

更新日期：1997-03-21 00:00:00

abstract：:We investigated the localization of components of translational machinery and their regulators in the postsynaptic region. We examined several components, especially those involved in translational regulation: components of (1) MAPK-Mnk-eIF4E, (2) PI3-kinase-PDK-Akt/PKB-FRAP/mTOR-PHAS/4EBP, (3) p70S6K-S6 ribosomal pro...

journal_title：Brain research

authors： Asaki C,Usuda N,Nakazawa A,Kametani K,Suzuki T

更新日期：2003-05-16 00:00:00

abstract：:In the adult brain, γ-amino butyric acid (GABA) is an inhibitory neurotransmitter, whereas it acts as an excitatory transmitter in the immature brain, and may be involved in morphogenesis. In the present study, we immunohistochemically examined the developmental changes in GABA signaling in the embryonic mouse cervica...

journal_title：Brain research

authors： Kosaka Y,Kin H,Tatetsu M,Uema I,Takayama C

更新日期：2012-11-27 00:00:00

abstract：:This EEG study (N=33) examined event-related potentials associated with conflict between activated responses in the Stroop task, in order to examine the conflict monitoring theory of cognitive control, which predicts the strength of exerted control to be proportional to the detected level of conflict. However, existin...

journal_title：Brain research

authors： Chuderski A,Senderecka M,Kałamała P,Kroczek B,Ociepka M

更新日期：2016-11-01 00:00:00

abstract：:Post-hypoxic myoclonus is a movement disorder characterized by brief, sudden involuntary muscle jerks. Although the mechanism underlying this disorder remains unclear, earlier pharmacological studies indicated that aberrant activity of specific neuronal circuitry in the central nervous system causes this disorder. In ...

journal_title：Brain research

authors： Tai KK,Truong DD

更新日期：2005-10-19 00:00:00

abstract：:Histopathological changes induced by intrahippocampal injections of low doses of kainic acid (17.5 ng/site) were investigated in rats. Kainic acid produced a selective loss of CA3 pyramidal and hilar neurons. The development of kainic acid-induced neuronal injury was not accompanied by any detectable loss of histologi...

journal_title：Brain research

authors： Théorêt Y,Earnhardt TS,Bouldin TW,Krigman MR

更新日期：1988-05-24 00:00:00

abstract：:A pathway from the pretectal region to the dorsal division of the lateral geniculate body has been studied by autoradiography in adult cats following injection of tritium-labeled amino acids into the meso-diencephalic border zone. The findings suggest that the pretecto-geniculate connection arises in the ipsilateral n...

journal_title：Brain research

authors： Graybiel AM,Berson DM

更新日期：1980-08-11 00:00:00

abstract：:The distribution of pituitary adenylate cyclase-activating polypeptide (PACAP) was examined in the tooth pulp. In rat and human tooth pulps, PACAP-immunoreactive (IR) nerve fibers were observed around blood vessels and in the subodontoblastic and odontoblastic layers. The predentine and dentine were devoid of such ner...

journal_title：Brain research

authors： Ichikawa H,Sugimoto T

更新日期：2003-08-08 00:00:00

abstract：:Early environmental factors can modulate the development of the hypothalamic-pituitary-adrenal (HPA) axis response to stress, together with subsequent brain functions and emotional behaviors. Two rat strains, Sprague-Dawley (SD) and Fischer 344 (F344), are known to exhibit differences in HPA axis reactivity and anxiet...

journal_title：Brain research

authors： Uchida S,Hara K,Kobayashi A,Otsuki K,Hobara T,Yamagata H,Watanabe Y

更新日期：2010-02-26 00:00:00

abstract：:The ultrastructural features of the serotoninergic innervation of the rat dentate gyrus in normal adults and in animals receiving raphe nuclear area transplants was investigated using an antibody to serotonin (5-HT). Neonatal rats received a lesion of the fimbria-fornix and entorhinal cortex. Three days later, a porti...

journal_title：Brain research

authors： Anderson KJ,Holets VR,Mazur PC,Lasher RS,Cotman CW

更新日期：1986-03-26 00:00:00

abstract：:Surgical tissue samples of the human dentate gyrus were immunostained for glutamate decarboxylase (GAD), the gamma-aminobutyric acid (GABA)-synthesizing enzyme, and studied by both light and electron microscopy. Immunoreactive neurons and terminals displayed similar morphological characteristics as known from studies ...

journal_title：Brain research

authors： Schlander M,Thomalske G,Frotscher M

更新日期：1987-01-13 00:00:00

abstract：:The distribution of neurocalcin-immunoreactive (NC-ir) primary sensory neurons was examined in the trigeminal ganglion (TG), mesencephalic trigeminal tract nucleus (Mes5) and intraoral structures. NC-ir primary sensory neurons were located in the TG but not the Mes5. The coexpression study demonstrated that virtually ...

journal_title：Brain research

authors： Ichikawa H,Hidaka H,Sugimoto T

更新日期：2000-05-02 00:00:00

abstract：:The present study examined the effects of excitotoxins which activate distinct excitatory amino acid (EAA) receptor subtypes on the levels of Methionine-enkephalin-like immunoreactivity (ME-i.r.) in the striatum and globus pallidus, with a view to developing a model of the striatopallidal enkephalin deficit that preva...

journal_title：Brain research

authors： Ruzicka BB,Jhamandas K

更新日期：1990-12-17 00:00:00

abstract：:The distinction between neural mechanisms of explicit and implicit expressions of memory has been well studied at the retrieval stage, but less at encoding. In addition, dissociations obtained in many studies are complicated by methodological difficulties in obtaining process-pure measures of different types of memory...

journal_title：Brain research

authors： Meng Y,Ye X,Gonsalves BD

更新日期：2014-10-17 00:00:00

abstract：:The neurons that produce gonadotrophin-releasing hormone (GnRH) are mainly found in the medial preoptic area (MPOA) and constitute a common final pathway to the control of luteinizing hormone (LH) surge on proestrus. The control of GnRH secretion depends on several neurotransmitters, such as serotonin (5-HT), noradren...

journal_title：Brain research

authors： Lima FB,Szawka RE,Anselmo-Franci JA,Franci CR

更新日期：2007-04-20 00:00:00

abstract：:Sex hormone binding globulin (SHBG) is found in the brain and acts directly on plasma membrane-associated receptors in the prostate gland. Infusing SHBG into the medial preoptic area or medial basal hypothalamus of female rats increases their female sexual receptivity. SHBG, SHBG plus estradiol (SHBG-E), and SHBG-E pl...

journal_title：Brain research

authors： Caldwell JD,Moe BD,Hoang J,Nguyen T

更新日期：2000-08-18 00:00:00

abstract：:In the present study we found that mesencephalic trigeminal (Mes-V) neurons of the rat are innervated by nitrergic fibers and that nitric oxide (NO) modifies the electrophysiological properties of these cells. Mes-V neurons were surrounded by a network of fibers that contained neuronal nitric oxide synthase (nNOS); th...

journal_title：Brain research

authors： Pose I,Sampogna S,Chase MH,Morales FR

更新日期：2003-01-17 00:00:00

abstract：:During the last few years, recombinant viral vectors derived from adenovirus (Ad), adeno-associated virus (AAV) or lentivirus (LV) have been developed into highly effective vehicles for gene transfer to the adult central nervous system. In recent experiments, in the rat model of Parkinson's disease, all three vector s...

journal_title：Brain research

authors： Björklund A,Kirik D,Rosenblad C,Georgievska B,Lundberg C,Mandel RJ

更新日期：2000-12-15 00:00:00

abstract：:Chemokine receptors, and in particular CXCR4 and CCR5 play a key role in the neuropathogenesis of Human Immunodeficiency Virus-1 (HIV)4 associated dementia (HAD). Thus, new insight into the expression of CXCR4 in the central nervous system may help develop therapeutic compounds against HAD. Brain-derived neurotrophic ...

journal_title：Brain research

authors： Ahmed F,Tessarollo L,Thiele C,Mocchetti I

更新日期：2008-08-28 00:00:00

abstract：:Selective D1 (SCH-23390) and D2 (eticlopride and sulpiride) dopamine receptor antagonists were assessed for their ability to reverse the effects of 1.0 mg/kg D-amphetamine on excitatory motor-related neurons in the striatum of freely moving rats. SCH-23390 (0.125, 0.25, 0.5 and 1.0 mg/kg) rapidly and consistently bloc...

journal_title：Brain research

authors： Rosa-Kenig A,Puotz JK,Rebec GV

更新日期：1993-08-13 00:00:00

abstract：:It has been hypothesized on the basis of animal models of epilepsy that abnormal neural activity in epilepsy may be related to reorganized neural circuits that facilitate epileptogenesis. Little evidence of this was available for human epilepsy. This paper provides the first evidence of such reorganization of a hippoc...

journal_title：Brain research

authors： de Lanerolle NC,Kim JH,Robbins RJ,Spencer DD

更新日期：1989-08-28 00:00:00

abstract：:In the present study, we assessed the beneficial synergistic effects of concurrent treatment with low doses of cilostazol and probucol against focal cerebral ischemic infarct in rats. The ischemic infarct induced by 2-h occlusion of middle cerebral artery (MCA) and 22-h reperfusion was significantly reduced in rat bra...

journal_title：Brain research

authors： Park SY,Lee JH,Kim CD,Rhim BY,Hong KW,Lee WS

更新日期：2007-07-09 00:00:00

abstract：:Mouse brain expresses three principal glucose transporters. Glut1 is an endothelial marker and is the principal glucose transporter of the blood-brain barrier. Glut3 and Glut6 are expressed in glial cells and neural cells. A mouse line with a null allele for Glut3 has been developed. The Glut3(-/-) genotype is intraut...

journal_title：Brain research

authors： Stuart CA,Ross IR,Howell ME,McCurry MP,Wood TG,Ceci JD,Kennel SJ,Wall J

更新日期：2011-04-12 00:00:00

abstract：:Corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) are pivotal mediators of the hormonal response to stressors and are found within neurons of the paraventricular nucleus of the hypothalamus (PVN) and several extrahypothalamic sites where expression is activity-dependent. Previous work has shown incr...

journal_title：Brain research

authors： Foradori CD,Lund TD,Nagahara AH,Koenig JI,Handa RJ

更新日期：2007-08-20 00:00:00

abstract：:In anesthetized, artificially ventilated cats, pretreated with the muscarinic antagonist scopolamine, the effect of naloxone on the efficacy of nicotinic transmission in the superior cervical ganglion was used as a test of endogenous opioid release by the preganglionic axons. The cervical sympathetic trunk (CST) was s...

journal_title：Brain research

authors： Zhang C,Bachoo M,Polosa C

更新日期：1991-05-10 00:00:00

abstract：:The globus pallidus plays a critical role in movement regulation. Morphological studies have shown that group I mGluRs including mGluR1 and mGluR5 are expressed in the globus pallidus. Up to now, little is known about the in vivo electrophysiological effects of group I mGluRs on the pallidal neurons. The present study...

journal_title：Brain research

authors： Sun XR,Chen L,Chen WF,Yung WH

更新日期：2012-10-05 00:00:00

abstract：:Motoneuron phenotype in the spinal cord is regulated by an intrinsic genetic program, extrinsic environmental signals and target-derived molecules. Axonal lesions trigger a phenotype switch to foster repair phenomena and axonal re-growth. We have investigated the influence of the long-term treatment with thyroid hormo...

journal_title：Brain research

authors： Giardino L,Giuliani A,Bettelli C,Calzà L

更新日期：2002-01-25 00:00:00