Spinal cord serotonin release and raised blood pressure after brainstem kainic acid injection.

Abstract:

:The recently developed technique of in vivo dialysis has permitted us to make direct measurements of serotonin release in a specific region of the spinal cord and to relate this to changes in blood pressure elicited by chemical stimulation of the brainstem. In the present experiments we have shown that chemical stimulation of bulbospinal neurons in the region of the B3 cell group in the ventromedial medulla, causes an increase in the release of serotonin in the thoracic spinal cord and that this release is associated with an increase in blood pressure.

journal_name

Brain Res

journal_title

Brain research

authors

Pilowsky PM,Kapoor V,Minson JB,West MJ,Chalmers JP

doi

10.1016/0006-8993(86)91318-1

subject

Has Abstract

pub_date

1986-02-26 00:00:00

pages

354-7

issue

1-2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(86)91318-1

journal_volume

366

pub_type

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