Rat olfactory neurons express a 200 kDa neurofilament.

abstract：:The blood-brain barrier consists of the cerebral microvascular endothelium, pericytes, astrocytes, and neurons. In this study, we analyzed the influence of primary porcine brain capillary pericytes on the barrier integrity of primary porcine brain capillary endothelial cells in a species-consistent in vitro coculture ...

journal_title：Brain research

authors： Thanabalasundaram G,Pieper C,Lischper M,Galla HJ

更新日期：2010-08-06 00:00:00

abstract：:Opiates and cannabinoids are among the most widely consumed habit-forming drugs in humans. Several studies have demonstrated the existence of interactions between both kind of drugs in a variety of effects and experimental models. The present study has been focused to determine whether perinatal delta9-tetrahydrocanna...

journal_title：Brain research

authors： Vela G,Martín S,García-Gil L,Crespo JA,Ruiz-Gayo M,Fernández-Ruiz JJ,García-Lecumberri C,Pélaprat D,Fuentes JA,Ramos JA,Ambrosio E

更新日期：1998-10-05 00:00:00

abstract：:In the present study, we used an innovative music-rest interleaved fMRI paradigm to investigate the neural correlates of tinnitus distress. Tinnitus is a poorly-understood hearing disorder where individuals perceive sounds, in the absence of an external source. Although the great majority of individuals habituate to c...

journal_title：Brain research

authors： Shahsavarani S,Schmidt SA,Khan RA,Tai Y,Husain FT

更新日期：2021-01-07 00:00:00

abstract：:The distribution of inositol 1,4,5-trisphosphate (InsP3) 3-kinase was studied in the adult rat brain, using polyclonal antibodies raised against the purified 50,000-Da rat brain enzyme by immunohistochemistry and Western blot, in addition to enzymatic assay. Immunohistochemically, the enzyme was detected in neurons, w...

journal_title：Brain research

authors： Mailleux P,Takazawa K,Erneux C,Vanderhaeghen JJ

更新日期：1991-01-25 00:00:00

abstract：:Traumatic injury to the peripheral and central nervous systems very often causes axotomy, where an axon loses connections with its target resulting in loss of function. The axon segments distal to the injury site lose connection with the cell body and degenerate. Axotomized neurons in the periphery can spontaneously m...

journal_title：Brain research

authors： Smith TP,Sahoo PK,Kar AN,Twiss JL

更新日期：2020-08-01 00:00:00

abstract：:The aim of this study was to determine if a prolonged period (7 or 14 days) of hypodynamia-hypokinesia (HH) affects the conduction of afferent input and the cortical and spinal responsiveness. Acute recordings of cortical and spinal somatosensory evoked potentials (SEPs) were performed after stimulation of the sciatic...

journal_title：Brain research

authors： Canu MH,Langlet C,Dupont E,Falempin M

更新日期：2003-07-18 00:00:00

abstract：:The concentration of noradrenaline (NA), dopamine (DA), serotonin (5-HT), and their metabolites was measured in hypothalamic and hippocampal brain tissue obtained from non-pregnant, 15- or 20-day pregnant and 4-day postpartum rats. At 20 days of pregnancy, hypothalamic NA and DA concentrations were significantly decre...

journal_title：Brain research

authors： Glaser J,Russell VA,Taljaard JJ

更新日期：1992-04-17 00:00:00

abstract：:The muscarinic cholinergic receptor of rat eccrine sweat gland was characterized using quantitative autoradiography and [3H]QNB as radioligand. The distribution of radioligand was maximal in the secretory coil. Autoradiographic competition binding studies were performed using selective antagonists to M1 (pirenzepine),...

journal_title：Brain research

authors： Torres NE,Zollman PJ,Low PA

更新日期：1991-05-31 00:00:00

abstract：:This study investigated the effects of N6-cyclopentyladenosine (CPA), a potent and selective adenosine A1 receptor (A1R) agonist in normal and nerve-injured rats and mechanisms of its action by behavioral tests and electrophysiological technique. The results showed: (1) In normal rats, intraperitoneal administration o...

journal_title：Brain research

authors： Gong QJ,Li YY,Xin WJ,Wei XH,Cui Y,Wang J,Liu Y,Liu CC,Li YY,Liu XG

更新日期：2010-11-18 00:00:00

abstract：:There is evidence that heme oxygenase plays a role in cellular defense against reactive oxygen species and thereby has neuroprotective effects. We examined the interaction of Neotrofin, a cognitive-enhancing and neuroprotective drug, with the heme oxygenase system. In adult rats, both a single administration or seven ...

journal_title：Brain research

authors： Wang X,Hauptmann N,Taylor E,Foreman M,Khawli LA,Maines MD

更新日期：2003-02-07 00:00:00

abstract：:In normal adult cats we measured the density of staining for the activity of succinate dehydrogenase (SDH staining) in ventral horn cells of different sizes. The measurements were restricted to that part of the lumbar ventral horn (L6-L7) which is known to contain motoneurones of the peroneal nerve. A statistically si...

journal_title：Brain research

authors： Donselaar Y,Kernell D,Eerbeek O

更新日期：1986-10-15 00:00:00

abstract：:Amyloid β-protein (Aβ) is the major component of extracellular plaques in the brains of patients with Alzheimer's disease. It has been suggested that the interaction of Aβ with membrane cholesterol is essential for Aβ to exert neurotoxicity; however, the effect of phospholipids, another major membrane lipid component,...

journal_title：Brain research

authors： Ko M,Hattori T,Abdullah M,Gong JS,Yamane T,Michikawa M

更新日期：2016-07-01 00:00:00

abstract：:Hippocampal neurogenesis plays a very important role in learning and memory functions. In a search for best neurological drugs that protect neuronal cells and stimulate neurogenesis with no side effects, cannabinoids proved to be a strong group of substances having many beneficial properties. The aim of this study was...

journal_title：Brain research

authors： Andres-Mach M,Haratym-Maj A,Zagaja M,Rola R,Maj M,Chrościńska-Krawczyk M,Luszczki JJ

更新日期：2015-10-22 00:00:00

abstract：:The synaptic relationship between neuronal structures reacting with antibodies to tyrosine hydroxylase (TH) and Leu- or Met-enkephalin (ENK) was studied by the 'mirror technique' in adjacent sections of rat neostriatum. TH-immunoreactive (TH-IR) axonal boutons surrounding the neural perikarya and proximal dendrites of...

journal_title：Brain research

authors： Kubota Y,Inagaki S,Kito S,Takagi H,Smith AD

更新日期：1986-03-05 00:00:00

abstract：:The distribution of antidiabetic sulfonylurea [( 3H]glibenclamide) binding sites is heterogeneous in rat brain. Pyramidal and extrapyramidal motor system contain the highest densities of sites, particularly in the substantia nigra and in the globus pallidus. Only low levels are present in the hypothalamic nuclei and t...

journal_title：Brain research

authors： Mourre C,Ben Ari Y,Bernardi H,Fosset M,Lazdunski M

更新日期：1989-05-01 00:00:00

abstract：:Sex differences in cocaine's mechanisms of action and behavioral effects have been widely reported. However, little is known about how sex influences intracellular signaling cascades involved with drug-environment associations. We investigated whether ERK/CREB intracellular responses in the mesocorticolimbic circuitry...

journal_title：Brain research

authors： Nygard SK,Klambatsen A,Hazim R,Eltareb MH,Blank JC,Chang AJ,Quinones-Jenab V,Jenab S

更新日期：2013-07-03 00:00:00

abstract：:Human subjects were asked to perform sinusoidal tracking movements (0.5--3.0 Hz) with their forearms while external torque disturbances were applied at the elbow. The changes in angular position, velocity, and acceleration produced by these disturbances were found to be represented in the reflex changes in EMG activit...

journal_title：Brain research

authors： Dufresne JR,Soechting JF,Terzuolo CA

更新日期：1980-07-07 00:00:00

abstract：:The syndrome of benign familial neonatal convulsions (BFNC) is characterized by seizures starting within the first days of life and disappearing within weeks to months. BFNC is caused by loss-of-function mutations in the potassium channels KCNQ2 and KCNQ3 which can well explain the resulting neuronal hyperexcitability...

journal_title：Brain research

authors： Weber YG,Geiger J,Kämpchen K,Landwehrmeyer B,Sommer C,Lerche H

更新日期：2006-03-10 00:00:00

abstract：:Intracranial pressure (ICP) was monitored to evaluate the therapeutic effect of hyperbaric oxygen (HBO(2)) treatment following traumatic brain injury (TBI). This subject is controversial. The aim of our study was to determine whether HBO(2) treatment has a therapeutic effect on ICP dynamics and survival following seve...

journal_title：Brain research

authors： Rogatsky GG,Kamenir Y,Mayevsky A

更新日期：2005-06-21 00:00:00

abstract：:Zinc and other cations were iontophoretically applied to neurones in the frontoparietal cortex of urethane-anaesthetised rats and their effect on the activity of these cells was examined. Slow and often prolonged increases in firing rate occurred in 45.2% of neurones after zinc application and 72.7% after barium. Calc...

journal_title：Brain research

authors： Wright DM

更新日期：1984-10-08 00:00:00

abstract：:The analgesic effect of clonidine in spontaneously hypertensive rats (SHR) and in normotensive Sprague-Dawley (SD) rats was assessed by using the formalin pain test. The analgesic response of SD rats to low doses (15-60 micrograms/kg i.p.) but not to a high dose (150 micrograms/kg i.p.) of clonidine was inhibited by n...

journal_title：Brain research

authors： Mastrianni JA,Abbott FV,Kunos G

更新日期：1989-02-13 00:00:00

abstract：:Microglial reactivity in the red nucleus of rats was studied following upper cervical and lower thoracic rubrospinal tractotomy using the lectin binding method. Following axotomy, the contralateral nucleus containing the axotomized neurons was identified using the retrograde tracer Fast blue. It was subdivided into do...

journal_title：Brain research

authors： Tseng GF,Wang YJ,Lai QC

更新日期：1996-04-09 00:00:00

abstract：:Cells in layers II-III or VI were activated by microdrop application of acetylcholine (ACh), while monitoring the intracellular response of layer V pyramidal cells. This enabled the tracing of functional connections between the cells of layers II-III or VI with those of layer V. ACh activation of layer II-III or VI ce...

journal_title：Brain research

authors： Kenan-Vaknin G,Malach R,Segal M

更新日期：1992-03-06 00:00:00

abstract：:The growth inhibitory factor (GIF) is a new metallothionein (MT)-like protein that is downregulated in Alzheimer's disease (AD) brain. The biological function of GIF has not been fully clarified yet. We have raised an antibody to the synthetic polypeptide that is specific for rat GIF. The purified antibody reacted to ...

journal_title：Brain research

authors： Hozumi I,Inuzuka T,Hiraiwa M,Uchida Y,Anezaki T,Ishiguro H,Kobayashi H,Uda Y,Miyatake T,Tsuji S

更新日期：1995-08-07 00:00:00

abstract：:The present study investigated the effect of locally infused guanfacine, an alpha2A-adrenergic agonist, into the ventral prefrontal cortex (PFv) on visuomotor associative learning. Two monkeys were well trained on a two-problem visuomotor associative task: the monkeys performed movement A if presented with a circle pa...

journal_title：Brain research

authors： Wang M,Tang ZX,Li BM

更新日期：2004-10-22 00:00:00

abstract：:Transport of fragmented DNA in apical dendrites of the CA1 pyramidal neurons of gerbil hippocampus is observed in the apoptotic process following transient forebrain ischemia. The time-course of specific DNA fragmentation was examined after the ischemic insult by in situ nick-end-labeling method and fluorescence detec...

journal_title：Brain research

authors： Hara A,Niwa M,Iwai T,Nakashima M,Yano H,Uematsu T,Yoshimi N,Mori H

更新日期：1998-09-28 00:00:00

abstract：:Rats were trained on a radial maze and then given electrolytic lesions of the MS followed by a single intraseptal injection of 5 micrograms of NGF. Three days later they were re-tested on the maze. They were also post-operatively tested for hyperemotionality. MS lesions severely impaired performance on the radial maze...

journal_title：Brain research

authors： Janis LS,Glasier MM,Martin G,Stackman RW,Walsh TJ,Stein DG

更新日期：1995-05-08 00:00:00

abstract：:After injections of 6-hydroxydopamine (6-OHDA) along the medial forebrain bundle in the lateral hypothalamus, rats failed to acquire a one-way active avoidance response or failed to perform a previously acquired active avoidance response. Such rats, however, acquired a passive avoidance response and a conditioned tast...

journal_title：Brain research

authors： Smith GP,Levin BE,Ervin GN

更新日期：1975-05-09 00:00:00

abstract：:Neonatal treatment with gonadal steroids has been reported to alter morphological as well as functional development in various regions of the brain and spinal cord. Among the observed alterations are changes in numbers of neurons and in the organization and numbers of synapses. These regions have been found to be sexu...

journal_title：Brain research

authors： Wright LL,Smolen AJ

更新日期：1983-06-01 00:00:00

abstract：:Suction lesions of the right frontal cerebral cortex in rats induce a period of spontaneous hyperactivity. The hyperactivity, as measured by an increase in running wheel activity begins about one week post-operatively and continues throughout the remainder of a 30-day observation period. The increased activity is acco...

journal_title：Brain research

authors： Pearlson GD,Robinson RG

更新日期：1981-08-10 00:00:00