Ultrastructural evidence of dopaminergic input to enkephalinergic neurons in rat neostriatum.

Abstract:

:The synaptic relationship between neuronal structures reacting with antibodies to tyrosine hydroxylase (TH) and Leu- or Met-enkephalin (ENK) was studied by the 'mirror technique' in adjacent sections of rat neostriatum. TH-immunoreactive (TH-IR) axonal boutons surrounding the neural perikarya and proximal dendrites of ENK-immunoreactive (ENK-IR) neurons were very thin (0.1-0.4 micrograms). They contained many small clear vesicles and sometimes had symmetrical membrane specializations. This provides morphological evidence for catecholaminergic, presumably dopaminergic inputs to rat striatal enkephalin neurons.

journal_name

Brain Res

journal_title

Brain research

authors

Kubota Y,Inagaki S,Kito S,Takagi H,Smith AD

doi

10.1016/0006-8993(86)91622-7

subject

Has Abstract

pub_date

1986-03-05 00:00:00

pages

374-8

issue

1-2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(86)91622-7

journal_volume

367

pub_type

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