Abstract：
:Suction lesions of the right frontal cerebral cortex in rats induce a period of spontaneous hyperactivity. The hyperactivity, as measured by an increase in running wheel activity begins about one week post-operatively and continues throughout the remainder of a 30-day observation period. The increased activity is accompanied by a bilateral decrease in norepinephrine concentrations in both the ipsilateral and contralateral cortex and locus coeruleus. Identical lesions of the left frontal cerebral cortex produce neither the hyperactivity nor a decrease in norepinephrine concentrations. These experiments have reproduced many of the behavioral and biochemical asymmetries seen after middle cerebral artery ligation; however, suction lesions are both simpler to produce and histologically less variable in their effects.
journal_name
Brain Resjournal_title
Brain researchauthors
Pearlson GD,Robinson RGdoi
10.1016/0006-8993(81)91303-2subject
Has Abstractpub_date
1981-08-10 00:00:00pages
233-42issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(81)91303-2journal_volume
218pub_type
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