Abstract:
:Zebrafish as a neurogenetic model system depends on the correct neuroanatomical understanding of its brain organization. Here, we address the unresolved question regarding a possible zebrafish homologue of the dorsal pallial division, the region that in mammals gives rise to the isocortex. Analyzing the distributions of nicotine adenine dinucleotide phosphate diphorase (NADPHd) activity and parvalbumin in the anterior zebrafish telencephalon, we show that against previous assumptions the central (Dc) zone possesses its own germinative region in the dorsal proliferative zone. We define the central (Dc) zone as topologically corresponding to the dorsal pallial division of other vertebrates (mammalian isocortex). In addition, we confirm through BrdU-labeling experiments that the posterior (Dp) zone is formed by radial migration and homologous to the mammalian piriform cortex. Based on our results, we propose a new developmental and organizational model of the zebrafish pallium-one which is the result of a complex outward-inward folding.
journal_name
Brain Resjournal_title
Brain researchauthors
Mueller T,Dong Z,Berberoglu MA,Guo Sdoi
10.1016/j.brainres.2010.12.089subject
Has Abstractpub_date
2011-03-24 00:00:00pages
95-105eissn
0006-8993issn
1872-6240pii
S0006-8993(11)00013-8journal_volume
1381pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::High-affinity uptake of norepinephrine (NE) and dopamine (DA) were determined in synaptosomes of brain regions from four genetically related inbred rat strains, all derived from the Wistar-Kyoto rat: SHR, WKY, WKHA and WKHT strains. SHRs express hypertension and hyperactivity, WKHAs express hyperactivity alone, WKHTs ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)91369-p
更新日期:1992-07-17 00:00:00
abstract:UNLABELLED:Mating in rabbits lasts only 3-5s but profoundly changes the female׳s physiology and behavior (e.g., inhibition of scent-marking and ambulation, changes in EEG, and release of GnRH). The behavioral responsiveness to copulation is reduced in lactating rabbits, relative to estrous does, but is enhanced after s...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2015.02.033
更新日期:2015-05-22 00:00:00
abstract::Purkinje cell dendritic arborizations were studied in HRP intracellularly stained mature neurons grown during 30-50 days in organotypic cerebellar cultures from newborn kittens. The effects of afferent fiber depletions on the final dendritic topological parameters were investigated by computer assisted methods. Three ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(83)90051-3
更新日期:1983-12-05 00:00:00
abstract::Rhythmic caffeine hyperpolarizations generated in bullfrog sympathetic ganglion cells are assumed to be caused by periodic increase in gK due to rise in [Ca2+]i7--9,13. Caffeine-induced outward currents seem to be composed of two different components, which show different pharmacological natures and also different dep...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90263-3
更新日期:1982-07-15 00:00:00
abstract::We previously reported that the antinociceptive effect of morphine on the thermal tail withdrawal reflex (tail flick, TF) was reduced in rats that had practiced the TF response prior to morphine administration. This phenomenon, termed behavioral tolerance, was observed even when rats were spinally transected following...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(92)90342-7
更新日期:1992-05-22 00:00:00
abstract::We hypothesized that abnormal activity and adrenergic sensitivity in injured dorsal root ganglion (DRG) neurons are due to an intrinsic alteration of the cell body membrane. We investigated the effects of adrenergic stimulus on the activities of Ca2+ and K+ channels of DRG neurons in a rat chronic constriction injury ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)01499-7
更新日期:1999-06-19 00:00:00
abstract::The purpose of this study was to investigate morphological characteristics of the synaptic relations of choline acetyltransferase (ChAT)-positive terminals that are made with a variety of post-synaptic profiles in the lateralis medialis-suprageniculate nuclear complex (LM-Sg) using ChAT, gamma-aminobutyric acid (GABA)...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(96)01208-5
更新日期:1997-01-30 00:00:00
abstract::PC12D cells, a subline of PC12 cells, extend neurites very rapidly in response to NGF, even when RNA synthesis is blocked. Several minutes after the initiation of a concentration gradient of NGF from a micropipette in the vicinity of PC12D cells, clear projections emerged from cells on the side facing the micropipette...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91387-0
更新日期:1994-09-05 00:00:00
abstract::Hippocampal neurogenesis plays a very important role in learning and memory functions. In a search for best neurological drugs that protect neuronal cells and stimulate neurogenesis with no side effects, cannabinoids proved to be a strong group of substances having many beneficial properties. The aim of this study was...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2015.07.028
更新日期:2015-10-22 00:00:00
abstract::The urethrogenital (UG) reflex is a spinal sexual reflex which is tonically inhibited in the intact male rat by neurons in the nucleus paragigantocellularis (nPGi). The medial preoptic area of the hypothalamus (MPOA) is involved in the activation of male sexual behavior. The present study examines the effect of hypoth...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)90638-6
更新日期:1994-02-28 00:00:00
abstract::Olfactory nerve input is required for the normal expression of tyrosine hydroxylase (TH) by dopaminergic neurons in the glomerular region of the rodent main olfactory bulb. To determine whether the olfactory nerve exerts a similar influence on neurons in other brain regions, we performed unilateral bulbectomies in rat...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)90977-3
更新日期:1989-09-11 00:00:00
abstract::To date several circuities in supraspinal site of the central nervous system have been known to engage in pain modulation. Lateral hypothalamus (LH) is known as part of the circuit of pain modulation among supraspinal sites. Its role in several animal pain models has been well defined. In this study, we examined the r...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2020.146674
更新日期:2020-04-01 00:00:00
abstract::The effects of intracerebral injections of brain-gut peptides in the preoptic region on the secretion of luteinizing hormone (LH) and prolactin (PRL) were examined in ovariectomized, estrogen-primed rats. Gastrin or cholecystokinin-octapeptide injection in the preoptic region induced a moderate increase of circadian r...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(87)90330-1
更新日期:1987-05-05 00:00:00
abstract::The development of bombesin-like peptides and their receptors was determined in 9 different rat brain regions. The concentration of immunoreactive bombesin increased dramatically in all brain regions examined during the third week after birth. In contrast, the density of [125I-Tyr4]bombesin binding sites was near maxi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(84)90107-x
更新日期:1984-08-01 00:00:00
abstract::Distribution of somatostatin (SS) immunoreactivity was observed in the preoptic-anterior hypothalamus (PO-AH) of the female rat brain. Six specific rabbit antibodies A (SS-14), B (SS-28), C (SS-28 complete), D (SS 14 and SS-28 both), E (SS preprohormone) and F (GHRH) were used for immunostaining using Avidin-Biotin Co...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)03164-4
更新日期:2001-05-11 00:00:00
abstract::The analgesia induced by 30-s footshock (1 mA) is enhanced and attenuated by decreasing and increasing the extraneuronal availability of serotonin (5-HT), respectively. In the present work we have shown the effect to be mediated by spinal 5-HT systems as the response was increased by depletion of spinal but not brain ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90448-6
更新日期:1982-04-15 00:00:00
abstract::We showed immunohistochemically the localization of 5 alpha-reductase-containing cells in the rat brain, using a rabbit antibody generated against 5 alpha-reductase rat type 1. The antibody was produced by injecting the synthetic peptide corresponding to the amino acids 38-53 of 5 alpha-reductase rat type 1, conjugate...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00188-6
更新日期:1996-05-25 00:00:00
abstract::Focal adhesion kinase (FAK) and proline-rich tyrosine kinase (PYK2) are two related non-receptor tyrosine kinases which are thought to play a role in transducing extracellular matrix (ECM)-derived survival signals into cells. The functions of FAK and PYK2 are linked to autophosphorylation of their specific tyrosine re...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2015.02.022
更新日期:2015-05-05 00:00:00
abstract::We investigated the bilateral organization of the descending spinal sympathetic projections that subserve adrenomedullary stimulation caused by insulin hypoglycemia or 2-deoxyglucose (2DG) cellular glucopenia in adult rats with right-sided hemisection of the cord at C6-C7 (i.e. above the site of origin of the adrenal ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90315-4
更新日期:1985-01-28 00:00:00
abstract::Patients with subcortical ischemic vascular disease (SIVD) may hold a high risk of cognitive impairment (CI) by affecting the functional connectivity (FC) of resting-state networks (RSNs). Current studies have mainly focused on the patients with CI but have ignored the prodromal stage when people suffered subcortical ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2019.03.022
更新日期:2019-07-15 00:00:00
abstract::Cortical superfusion with 6-aminomethyl-3-methyl, 1-4H-1,2,6-benzothiadiazine-1,1-diazide hydrocholoride (TAG) at a concentration which selectively blocks taurine (Tau) action fails to modify electroencephalographic (EEG) activity, cortical neuronal firing and caudate-induced inhibition of cortical neuronal activity. ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)91449-6
更新日期:1986-08-13 00:00:00
abstract::Brain/kidney (B/K) protein is a new protein of 474 amino acids, which contains two C2 domains structurally homologous to those present in synaptotagmins. The expression of B/K protein was identified in the rat retina and B/K protein immunoreactivity was localized to a number of ganglion cells, a few amacrine cells and...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02014-x
更新日期:2000-03-31 00:00:00
abstract::When nomifensine is employed to inhibit neuronal uptake, exposure to dopamine (DA) (0.1-0.3 microM) or apomorphine (0.01-0.1 microM) inhibited, in a concentration-dependent manner, the electrically evoked release of [3H]dopamine from slices of the rabbit caudate nucleus. Apomorphine inhibited transmitter release indep...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91605-1
更新日期:1985-06-24 00:00:00
abstract::Tactile stimulation of the body surface elicited climbing fiber responses in 5% of the 839 Purkinje cells recorded in the caudal posterior vermis (lobules VII-IX) of cats anesthetized with sodium pentobarbital. The cells responsive to tactile stimulation were mainly encountered around the prepyramidal fissure between ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90084-o
更新日期:1990-06-11 00:00:00
abstract::Melatonin is a hormone that mostly produced from the pineal gland, and it performs as a strong neuroprotectant to both neuron and glial cells against methamphetamine (METH)-induced neurotoxicity. Recently, it has been found that METH also damages the blood brain barrier (BBB) structure and function. However, the prote...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2016.08.045
更新日期:2016-11-01 00:00:00
abstract::This study shows that the axons of some raphespinal sympathoinhibitory neurons projecting to the third thoracic spinal segment emit branches in the third-fourth cervical spinal segments of cats. This was demonstrated by using time-controlled collision of neuronal action potentials initiated by stimuli applied at these...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)91417-5
更新日期:1988-02-16 00:00:00
abstract::The role of descending monoaminergic pathways in the antinociceptive effect of baclofen following intraperitoneal (i.p.) administration was investigated by determining the effect of intrathecal (i.t.) administration of neurotoxins [6-hydroxydopamine (6-OHDA) and 5,6-dihydroxytryptamine (5,6-DHT)] and receptor antagoni...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90279-3
更新日期:1985-05-27 00:00:00
abstract::Intracisternal administration of aluminum maltolate to rabbits produces a marked argyrophilic neurofibrillary degeneration (NFD) which is also immunoreactive for both phosphorylated and non-phosphorylated microtubule associated protein tau. Using tissue fixation in PBF, the monoclonal antibodies Tau-2 and AT8 stain th...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)01297-u
更新日期:1995-01-16 00:00:00
abstract::The aim of this study was to determine the effect of different concentrations of normobaric oxygen (NBO) on neurological function and the expression of caspase-3 and -9 in a rat model of acute cerebral ischaemia. Sprague-Dawley rats (n=120) were randomly divided into four groups (n=30 per group), including 3 groups gi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2015.05.027
更新日期:2015-08-27 00:00:00
abstract::The olfactory epithelium is comprised of bipolar sensory neurons, sustentacular cells, and basal cells. The sensory neurons have apical knobs and cilia, which project into the olfactory mucus toward the nasal lumen, and represent presumptive sites of odorant binding. Ionic currents, measured across this epithelium in ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91153-r
更新日期:1991-04-12 00:00:00