Abstract：
:Rhythmic caffeine hyperpolarizations generated in bullfrog sympathetic ganglion cells are assumed to be caused by periodic increase in gK due to rise in [Ca2+]i7--9,13. Caffeine-induced outward currents seem to be composed of two different components, which show different pharmacological natures and also different dependencies on membrane potential changes. These two components may be generated by activation of two voltage-dependent K+ currents, namely IK1 (the delayed rectifier K+ current) and IK2 (IM) of ganglion cells. These results suggested that at least two different gK systems were activated by [Ca2+]i in sympathetic ganglion cells.
journal_name
Brain Resjournal_title
Brain researchauthors
Koketsu K,Akasu T,Miyagawa Mdoi
10.1016/0006-8993(82)90263-3subject
Has Abstractpub_date
1982-07-15 00:00:00pages
369-72issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(82)90263-3journal_volume
243pub_type
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