The distribution of [3H]kainic acid binding sites in rat CNS as determined by autoradiography.

Abstract:

:The distribution of [3H]kainic acid (KA) binding sites in the rat CNS was determined by in vitro autoradiography. KA sites are distributed throughout the CNS gray matter in an anatomically specific pattern with telencephalic structures and the cerebellum accounting for the majority of the binding. These results, together with our previous finding that KA sites are greatly enriched at the synapse, suggest that KA binding sites are associated with select terminal fields, and hence may be involved in neurotransmission in certain CNS pathways.

journal_name

Brain Res

journal_title

Brain research

authors

Monaghan DT,Cotman CW

doi

10.1016/0006-8993(82)90981-7

subject

Has Abstract

pub_date

1982-12-02 00:00:00

pages

91-100

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(82)90981-7

journal_volume

252

pub_type

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