The role of plantar cutaneous mechanoreceptors in the control of compensatory stepping reactions evoked by unpredictable, multi-directional perturbation.

abstract：:With the increasing worldwide incidence of Alzheimer's disease (AD), there is a critical need for the discovery of more effective diagnostic methods. However, development of diagnostic tools in AD has been hindered by obstacles such as the absence of exact biomarkers. Apoptosis caused by amyloid-β (Aβ) plays an import...

journal_title：Brain research

authors： Lee JK,Wang K,Park MH,Kim N,Lee JY,Jin HK,Kim IS,Lee BH,Bae JS

更新日期：2016-09-01 00:00:00

abstract：:A modified glyoxylic acid technique was used to examine central and peripheral nervous tissues in Aplysia californica. In addition to confirming the distribution of catecholamines and serotonin in the central nervous system, the method demonstrated the presence of monoamines in the opaline gland and bag cell clusters ...

journal_title：Brain research

authors： Tritt SH,Lowe IP,Byrne JH

更新日期：1983-01-17 00:00:00

abstract：:Brain and anterior pituitary growth hormone (GH), thyroid-stimulating hormone (TSH) and luteinizing hormone (LH) were measured during fetal, neonatal, and pubertal life and into adulthood. Immunoassayable GH and TSH could be found in the fetal whole brain before their detection in the fetal pituitary. Developmental pa...

journal_title：Brain research

authors： Hojvat S,Emanuele N,Baker G,Connick E,Kirsteins L,Lawrence AM

更新日期：1982-08-01 00:00:00

abstract：:Voltage-activated calcium channel currents were recorded from differentiated human neuroblastoma cells. SK-N-SH-SY5Y (SH-SY5Y) line, using patch-clamp techniques. Experimental solutions were designed to suppress sodium and potassium channel currents, and barium ions were used as the charge carrier. Two distinct types ...

journal_title：Brain research

authors： Reuveny E,Narahashi T

更新日期：1993-02-12 00:00:00

abstract：:The feedback effect of activity of area 21a on orientation maps of areas 17 and 18 was investigated in cats using intrinsic signal optical imaging. A spatial frequency-dependent decrease in response amplitude of orientation maps to grating stimuli was observed in areas 17 and 18 when area 21a was inactivated by local ...

journal_title：Brain research

authors： Huang L,Chen X,Shou T

更新日期：2004-02-20 00:00:00

abstract：:The present study aimed to determine whether the observation of different grasps of the same object elicits automatic imitation of the kinematics of those grasps and this process influences the estimation of intrinsic target properties. In experiments 1 and 2, participants reached and grasped differently sized spheres...

journal_title：Brain research

authors： Gianelli C,Dalla Volta R,Barbieri F,Gentilucci M

更新日期：2008-07-07 00:00:00

abstract：:Effects of taurine on endogenous aspartic acid (Asp), glutamic acid (Glu) and gamma-aminobutyric acid (GABA) release has been investigated using synaptosomes prepared from rat cerebral cortex. Although basal release of these amino acids was not affected, taurine inhibited KCl (30 mM)-evoked overflow of Asp, Glu and GA...

journal_title：Brain research

authors： Kamisaki Y,Maeda K,Ishimura M,Omura H,Itoh T

更新日期：1993-11-12 00:00:00

abstract：:The time course of the neurogenesis of cells showing glutamic acid decarboxylase (GAD) immunoreactivity has been analyzed in the dorsal hippocampus and area dentata of the mouse. The quantitative data indicate that gamma-aminobutyric acid (GABA)ergic cells are generated prenatally, and that their peaks of neurogenesis...

journal_title：Brain research

authors： Soriano E,Cobas A,Fairén A

更新日期：1986-11-01 00:00:00

abstract：:Traumatic brain injury (TBI) is one of the largest health problems in the United States and affects both cognitive and motor function. Although weakness is common in TBI patients, few studies have demonstrated a reduction in strength in models of brain injury. We have developed a behavioral method to measure volitiona...

journal_title：Brain research

authors： Pruitt D,Hays S,Schmid A,Choua C,Kim L,Trieu J,Kilgard MP,Rennaker RL 2nd

更新日期：2014-09-25 00:00:00

abstract：:The effects of undernutrition during pregnancy and/or lactation periods on cortical structures have already been reported. However, its effect on non-cortical areas like the hypothalamic, that participates in the regulation of the autonomic nervous system or food intake, has not been extensively investigated. We studi...

journal_title：Brain research

authors： González-Pardo H,Gutiérrez-Sánchez JM,Menéndez-Patterson A,Arias JL

更新日期：1994-08-15 00:00:00

abstract：:Superfusion of slices of the dorsal zone of the lumbar enlargement with an artificial cerebrospinal fluid was used to investigate the possible modulation by GABA receptor ligands of the in vitro release of calcitonin gene-related peptide- and substance P-like materials (CGRPLM and SPLM) from the rat spinal cord. Where...

journal_title：Brain research

authors： Bourgoin S,Pohl M,Benoliel JJ,Mauborgne A,Collin E,Hamon M,Cesselin F

更新日期：1992-06-26 00:00:00

abstract：:The exposure of cultured rat striatal neurons to L-DOPA caused marked cell death. The L-DOPA cytotoxicity was inhibited by the addition of Mg2+ to and by the removal of Ca2+ from the culture medium, and also by the application of tetrodotoxin. Moreover, prolonged application of L-DOPA increased the glutamate content i...

journal_title：Brain research

authors： Maeda T,Cheng N,Kume T,Kaneko S,Kouchiyama H,Akaike A,Ueda M,Satoh M,Goshima Y,Misu Y

更新日期：1997-10-10 00:00:00

abstract：:A new compound, 3-((+/-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP), has been evaluated as an excitatory amino acid receptor antagonist using electrophysiological assays and radioligand binding. In autoradiographic preparations, CPP reduces L-[3H]glutamate binding in regions of the hippocampus rich in N-m...

journal_title：Brain research

authors： Harris EW,Ganong AH,Monaghan DT,Watkins JC,Cotman CW

更新日期：1986-09-10 00:00:00

abstract：:The understanding of sentences involves not only the retrieval of the meaning of single words, but the identification of the relation between a verb and its arguments. The way the brain manages to process word meaning and syntactic relations during language comprehension on-line still is a matter of debate. Here we re...

journal_title：Brain research

authors： Friederici AD,Weissenborn J

更新日期：2007-05-18 00:00:00

abstract：:In light of the evidence that calcium plays a critical role in excitotoxic neuronal death, it has been speculated that the metabotropic glutamate receptor may also contribute to excitotoxic damage through the mobilization of Ca2+ from intracellular stores. In the present study we examined this possibility by studying ...

journal_title：Brain research

authors： Koh JY,Palmer E,Lin A,Cotman CW

更新日期：1991-10-11 00:00:00

abstract：:Stanniocalcin (STC-1), a 50 kDa glycoprotein hormone that regulates calcium/phosphate homeostasis in bony fish and mammals, has been shown to be expressed in central neurons and choroid plexus, and to exert a protective effect against hypercalcemic and hypoxic damage to neurons. Circumventricular organs are known to f...

journal_title：Brain research

authors： Ratkovic S,Wagner GF,Ciriello J

更新日期：2008-07-07 00:00:00

abstract：:There are sex differences in the neurochemistry of brainstem nuclei that participate in the control of breathing as well as sex differences in respiratory responses to hypoxia. Central chemoreception refers to the detection within the brain of minute changes in carbon dioxide (CO(2)) levels and the subsequent modulati...

journal_title：Brain research

authors： Niblock MM,Gao H,Li A,Jeffress EC,Murphy M,Nattie EE

更新日期：2010-01-22 00:00:00

abstract：:The N400 is an event-related potential (ERP) component that is elicited by semantically meaningful stimuli; one of its defining characteristics is that it is amplified for sentence completions that are semantically unexpected or incongruous with the preceding context. Some prior reports using visual sentence reading p...

journal_title：Brain research

authors： Dien J,Michelson CA,Franklin MS

更新日期：2010-10-08 00:00:00

abstract：:The acquisition and retention of tolerance to the antinociceptive effect of supraspinal morphine on the tail withdrawal reflex was assessed in rats implanted with unilateral cannulae in the periaqueductal gray (PAG). Development of tolerance to daily microinjections of morphine was indicated by the return of the tail ...

journal_title：Brain research

authors： Siuciak JA,Advokat C

更新日期：1987-10-27 00:00:00

abstract：:Olfactory nerve input is required for the normal expression of tyrosine hydroxylase (TH) by dopaminergic neurons in the glomerular region of the rodent main olfactory bulb. To determine whether the olfactory nerve exerts a similar influence on neurons in other brain regions, we performed unilateral bulbectomies in rat...

journal_title：Brain research

authors： Guthrie KM,Leon M

更新日期：1989-09-11 00:00:00

abstract：:Subcutaneous administration of rotenone has recently attracted attention because of its convenience, simplicity and efficacy in replicating features of Parkinson's disease (PD) in animal models. However, the wide range of doses reported in the literature makes it difficult to evaluate the effectiveness of this techniq...

journal_title：Brain research

authors： Zhang ZN,Zhang JS,Xiang J,Yu ZH,Zhang W,Cai M,Li XT,Wu T,Li WW,Cai DF

更新日期：2017-01-15 00:00:00

abstract：:Experimental studies and clinical observations show that spinal cord lesions are greatly enlarged by a process called secondary cell death. A detailed understanding of the molecular and cellular processes underlying these events is still lacking. In clinical studies using methylprednisolone in spinal cord injured pati...

journal_title：Brain research

authors： Bartholdi D,Schwab ME

更新日期：1995-02-20 00:00:00

abstract：:The present study was designed to examine the trophic effect of sympathetic nerves on cerebrovascular hypertrophy in developmental hypertension. Unilateral superior cervical ganglionectomy was performed in spontaneously hypertensive rats at 4 weeks of age, and wall-to-lumen ratios of cerebral arteries were determined ...

journal_title：Brain research

authors： Sadoshima S,Fujii K,Yao H,Ibayashi S,Fujishima M

更新日期：1986-08-06 00:00:00

abstract：:Microspectrofluorimetric measurements of excitatory amino acid-evoked rises in intracellular free calcium concentration ([Ca2+]i), electrophysiological measurements of currents through single NMDA receptor-operated ion channels and estimates of cellular viability following NMDA challenge were employed to examine the i...

journal_title：Brain research

authors： Sawyer DC,McLarnon JG,Church J

更新日期：1995-11-06 00:00:00

abstract：:The insular cortex (IC) has been reported to modulate the cardiac parasympathetic activity of the baroreflex in unanesthetized rats. However, which neurotransmitters are involved in this modulation is still unclear. In the present study, we evaluated the possible involvement of local IC-noradrenergic neurotransmission...

journal_title：Brain research

authors： Alves FH,Crestani CC,Resstel LB,Correa FM

更新日期：2009-10-27 00:00:00

abstract：:In a previous study, we demonstrated that cholera toxin-A subunit, as well as the whole toxin, selectively blocks opioid-induced prolongation of the Ca2+ component of the action potential duration (APD) in dorsal root ganglion (DRG) neurons, indicating mediation of this excitatory effect by Gs-linked opioid receptors....

journal_title：Brain research

authors： Shen KF,Crain SM

更新日期：1990-10-29 00:00:00

abstract：:The roles of endogenous serotonin (5-HT) and 5-HT receptor subtypes in regulation of acetylcholine (ACh) release in frontal cortex of conscious rats were examined using a microdialysis technique. Systemic administration (1 and 3 mg/kg, i.p.) of the 5-HT-releasing agent p-chloroamphetamine (PCA) elevated ACh output in ...

journal_title：Brain research

authors： Yamaguchi T,Suzuki M,Yamamoto M

更新日期：1997-10-24 00:00:00

abstract：:The effect of lung inflation on the excitability of inspiratory neurons of the dorsal respiratory group was studied in decerebrate, paralyzed, artificially ventilated cats. Variations in the antidromic latency (AL) were used as a measure of the changes in excitability. The antidromic responses of single cells were rec...

journal_title：Brain research

authors： Davies RO,Metzler J,Silage DA,Pack AI

更新日期：1986-02-26 00:00:00

abstract：:Leumorphin, an opioid peptide whose functions are unknown, is found in mammalian brain and pituitary and stimulates lordosis behavior in estrogen-treated female rats. To elucidate the role of leumorphin in the physiological control of female sexual behavior, the levels of immunoreactive (ir) leumorphin as well as ir d...

journal_title：Brain research

authors： Suda M,Nakao K,Sakamoto M,Morii N,Sugawara A,Imura H

更新日期：1986-05-28 00:00:00

abstract：:Secretion of calcitonin gene-related peptide (CGRP) was studied with the model system of dispersed adult rat trigeminal ganglion cells. Veratridine stimulated secretion of CGRP immunoreactivity. Tetrodotoxin and local anesthetics inhibited veratridine-stimulated peptide secretion. These observations implicate sodium c...

journal_title：Brain research

authors： Peterfreund RA,Vale WW

更新日期：1986-08-13 00:00:00