Abstract:
:The aim of this study was to determine if a prolonged period (7 or 14 days) of hypodynamia-hypokinesia (HH) affects the conduction of afferent input and the cortical and spinal responsiveness. Acute recordings of cortical and spinal somatosensory evoked potentials (SEPs) were performed after stimulation of the sciatic nerve in control rats and in rats submitted to 7 or 14 days of HH. HH was obtained by unloading the hindquarter. HH induced some subtle modifications in the SEP characteristics. Latency was increased for the spinal and cortical SEPs after 7 days of HH, and restored after 14 days of HH. A decrease in the amplitude was observed after 14 days of HH for the cortical SEP only. At the end of the experiment, the compound action potential of the sciatic nerve was recorded in vitro in order to evaluate the mean conduction velocity. Results indicate that the nerve velocity was reduced after 14 days of HH. The results also suggest that sensory conduction and/or cortical and spinal excitability are changed after HH.
journal_name
Brain Resjournal_title
Brain researchauthors
Canu MH,Langlet C,Dupont E,Falempin Mdoi
10.1016/s0006-8993(03)02804-xsubject
Has Abstractpub_date
2003-07-18 00:00:00pages
162-8issue
1-2eissn
0006-8993issn
1872-6240pii
S000689930302804Xjournal_volume
978pub_type
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