In situ transblot and immunocytochemical comparisons of astrocytic connexin-43 responses to NMDA and kainic acid in rat brain.

abstract：:The blood-nerve barrier consists of continuous layers of cells linked by tight junctions and includes the endothelial cells which line the endoneurial capillaries and the perineurial cells which surround fascicles of nerve fibers. A facilitated transport carrier protein allows D-glucose to penetrate the barrier. To de...

journal_title：Brain research

authors： Gerhart DZ,Drewes LR

更新日期：1990-01-29 00:00:00

abstract：:Auditory transients (such as sound onset or a frequency transition within a continuous sound) are assumed to parse the auditory input into smaller units enabling the formation of unitary sound representations separately for each segment. This was discovered by using the mismatch negativity (MMN) component of the event...

journal_title：Brain research

authors： Weise A,Bendixen A,Müller D,Schröger E

更新日期：2012-06-29 00:00:00

abstract：:Nuclear factor κB (NFκB) signaling plays ubiquitous roles in inflammation, immune response and neurogenesis. G protein-coupled receptor kinase 5 (GRK5) can protect neurons from degeneration. GRK5 also mediates tumor necrosis factor-α (TNFα)-induced NFκB signaling through the phosphorylation of IκBα. Here, we show that...

journal_title：Brain research

authors： Zhang Y,Shen GL,Shangguan LJ,Yu Y,He ML

更新日期：2015-05-22 00:00:00

abstract：:The distributions of serotonin and catecholamines were examined within the central ganglia of juvenile Achatina through the histological localization of serotonin-like immunoreactivity and of glyoxylic acid-induced fluorescence. Somata containing these amines were widely distributed throughout all central ganglia exce...

journal_title：Brain research

authors： Croll RP

更新日期：1988-09-13 00:00:00

abstract：:Spontaneous, synchronous burst discharges originating in the CA2-CA3 region of guinea pig hippocampal slices occur when the concentration of magnesium in the perfusate is reduced below 250 microM. The burst frequency is greater than that seen with other convulsants and afterdischarge is common. Cyclic periods of burst...

journal_title：Brain research

authors： Schneiderman JH,MacDonald JF

更新日期：1987-04-28 00:00:00

abstract：:The patterns of expression of the Bcl-2, Bax, and Bcl-xL proteins were examined immunocytochemically in rat hippocampus and neocortex after severe hypobaric hypoxia (180 Torr for 3 h) and severe hypoxia preconditioned by intermittent mild hypoxia (360 Torr for 2 h daily, for 3 consecutive days, 24 h prior to severe hy...

journal_title：Brain research

authors： Rybnikova E,Sitnik N,Gluschenko T,Tjulkova E,Samoilov MO

更新日期：2006-05-17 00:00:00

abstract：:alpha-Adrenoreceptors are present in the ventricular (VZ) and subventricular (SVZ) zones of the mammalian embryonic forebrain, and contribute towards cell cycle controls in the germinal neuroepithelium [Pabbathi et al., Brain Res. 760 (1997) 22-33.]. Since noradrenaline-containing fibres from the locus coeruleus (LC) ...

journal_title：Brain research

authors： Popovik E,Haynes LW

更新日期：2000-01-24 00:00:00

abstract：:Nociceptin/orphanin FQ is an endogenous neuropeptide that plays important roles in several physiological functions including pain, anxiety, locomotion, learning, and memory. We previously reported that low doses of nociceptin improved the scopolamine-induced impairment of learning and memory in the passive avoidance t...

journal_title：Brain research

authors： Hiramatsu M,Miwa M,Hashimoto K,Kawai S,Nomura N

更新日期：2008-02-21 00:00:00

abstract：:The effects of 2-day and 7-day cortisol treatment on immunoreactive corticotropin (ACTH) and beta-endorphin concentrations were measured in the cerebral cortex, hippocampus, hypothalamus, and cerebellum in male rats. Plasma ACTH, beta-endorphin, corticosterone, and cortisol levels were also measured in parallel. Corti...

journal_title：Brain research

authors： Bagdy G,Calogero AE,Chrousos GP,Szemeredi K

更新日期：1989-06-12 00:00:00

abstract：:It is suggested that altered neuroplasticity contributes to the pathophysiology of schizophrenia and antipsychotics may exhibit some of their therapeutic efficacies by improving neurogenesis and/or proliferation of neural progenitors. The aim of this study is to investigate whether chronic antipsychotics treatment aff...

journal_title：Brain research

authors： Chikama K,Yamada H,Tsukamoto T,Kajitani K,Nakabeppu Y,Uchimura N

更新日期：2017-12-01 00:00:00

abstract：:Cortical projection areas and distribution and response characteristics of masseteric nerve-driven neurons (MDN) were studied by recording surface-evoked potentials and single neuronal activities elicited by stimulation of the contralateral masseteric nerve in cats. Neuronal activities of MDNs could be recorded in two...

journal_title：Brain research

authors： Iwata K,Itoga H,Ikukawa A,Hanashima N,Sumino R

更新日期：1985-09-02 00:00:00

abstract：:Dural afferent neurons are implicated in primary headaches including migraine. Although a significant portion of primary afferent neurons innervating the dura are myelinated A-type neurons, previous electrophysiological studies have primarily characterized the functional properties of small-sized C-type sensory neuron...

journal_title：Brain research

authors： Nakamura M,Jang IS

更新日期：2018-10-01 00:00:00

abstract：:10-fold higher doses in SW mice. Furthermore, cotreatment of 129/SvEv mice with morphine plus a low dose of naltrexone (ca. 0.1 microgram/kg) that markedly enhances and prolongs morphine's antinociceptive effects in SW mice did not enhance, and often attenuated6 h. The marked GM1-induced attenuation of morphine's anti...

journal_title：Brain research

authors： Crain SM,Shen K

更新日期：2000-02-21 00:00:00

abstract：:Intracellular free calcium concentration ([Ca2+]i) was measured in cultured explants of myenteric plexus neurones by using the fluorescent calcium indicator Indol in combination with patch-clamp techniques. The basal [Ca2+]i was 94 nM and spontaneous oscillations in the internal free calcium concentration were recorde...

journal_title：Brain research

authors： Trouslard J,Mirsky R,Jessen KR,Burnstock G,Brown DA

更新日期：1993-10-08 00:00:00

abstract：:Different mechanisms have been suggested to contribute to isoflurane-mediated neuroprotection. Previous studies have suggested that the protein Slit can abrogate neuronal death in mixed neuronal-glial cultures exposed to oxygen-glucose deprivation (OGD) and reperfusion (OGD/R). We hypothesized that isoflurane increase...

journal_title：Brain research

authors： Zhao XC,Zhang LM,Li Q,Tong DY,Fan LC,An P,Wu XY,Chen WM,Zhao P,Wang J

更新日期：2013-11-06 00:00:00

abstract：:Mammalian vestibular type I hair cells (VIHCs) are innervated by an afferent synaptic calyx which contains vesicles and is immunoreactive for GABA. We describe here the effects of GABA on electrophysiological properties and on cytosolic free-calcium levels ([Ca2+]i) of VIHCs isolated from guinea-pig ampullae. Whole-ce...

journal_title：Brain research

authors： Lapeyre PN,Kolston PJ,Ashmore JF

更新日期：1993-04-23 00:00:00

abstract：:We have investigated the receptor subtype(s) mediating the noradrenergic inhibition of cerebellar Purkinje cell spontaneous firing rate using local application of specific agonists and antagonists, in situ, via pressure microejection. Extracellular action potentials were recorded from Purkinje neurons in anesthetized ...

journal_title：Brain research

authors： Parfitt KD,Freedman R,Bickford-Wimer PC

更新日期：1988-10-18 00:00:00

abstract：:Hyperprolinemia type II is an autosomal recessive disorder caused by the severe deficiency of delta(1)-pyrroline-5-carboxylate dehydrogenase activity leading to tissue accumulation of proline (Pro). Most patients detected so far show neurological manifestations including epilepsy and mental retardation, whose pathophy...

journal_title：Brain research

authors： Delwing D,Bavaresco CS,Chiarani F,Wannmacher CM,Wajner M,Dutra-Filho CS,de Souza Wyse AT

更新日期：2003-11-21 00:00:00

abstract：:Deacetylation is a rapid clearance mechanism for ocular melatonin. We have studied the distribution of retinal melatonin deacetylase activity among vertebrate classes. Exogenous radiolabeled melatonin is metabolized by ocular tissue prepared from the amphibian Xenopus laevis, the reptile Anolis carolinensis, the teleo...

journal_title：Brain research

authors： Grace MS,Cahill GM,Besharse JC

更新日期：1991-09-13 00:00:00

abstract：:Preganglionic sympathetic neurons were labelled by retrograde transport of horseradish peroxidase, while catecholamine axon varicosities were marked by the uptake of 5-hydroxydopamine in the intermediolateral nucleus of the rat. The direct synaptic contacts from the catecholamine axons to the preganglionic sympathetic...

journal_title：Brain research

authors： Chiba T,Masuko S

更新日期：1986-08-20 00:00:00

abstract：:Aquaporin-4 (AQP4), the prominent water channel in the brain, is particularly concentrated in astrocytic endfeet membranes lining the capillaries and the pia. This localisation pattern makes it well suited to regulate the flow of water and the homeostasis of the interstitial fluid surrounding the neurons. Using immuno...

journal_title：Brain research

authors： Medici V,Frassoni C,Tassi L,Spreafico R,Garbelli R

更新日期：2011-01-07 00:00:00

abstract：:The concentrations of GABA, glutamate, aspartate, glycine, taurine, glutamine, asparagine and alanine were determined in the CSF of 10 Senegalese baboons (Papio papio) following initial ketamine anaesthesia and subsequent administration (4 h later) of different compounds known to alter either inhibitory or excitatory ...

journal_title：Brain research

authors： Valin A,Voltz C,Naquet R,Lloyd KG

更新日期：1991-01-04 00:00:00

abstract：:Differential circadian rhythms in 5-HT levels were found in the hypothalamus and pineal (but not in the cortex, hippocampus or midbrain) in ferrets kept in either long (14 h light/10 h dark) or short (8 h light/16 h dark) photoperiods. 5-HT decreased during the first 6 h of illumination in all areas examined from anim...

journal_title：Brain research

authors： Yates CA,Herbert J

更新日期：1979-11-02 00:00:00

abstract：:Hydrogen-rich water (HRW) has anti-oxidant activities, and it exerts neuroprotective effects during ischemia-reperfusion brain injury. Parvalbumin and hippocalcin are two calcium buffering proteins, which are involved in neuronal differentiation, maturation and apoptosis. The aim of this study was to investigate wheth...

journal_title：Brain research

authors： Han L,Tian R,Yan H,Pei L,Hou Z,Hao S,Li YV,Tian Q,Liu B,Zhang Q

更新日期：2015-07-30 00:00:00

abstract：:The studies were performed on operation material from 17- to 63-year-old patients and on fetuses at 19-23 weeks gestational age. Formaldehyde histofluorescence showed the presence of numerous perivascular adrenergic nerves around pial and intracerebral vessels, the carotid system being better supplied than the vertebr...

journal_title：Brain research

authors： Edvinsson L,Owman C,Sjöberg NO

更新日期：1976-10-22 00:00:00

abstract：:The distinction between neural mechanisms of explicit and implicit expressions of memory has been well studied at the retrieval stage, but less at encoding. In addition, dissociations obtained in many studies are complicated by methodological difficulties in obtaining process-pure measures of different types of memory...

journal_title：Brain research

authors： Meng Y,Ye X,Gonsalves BD

更新日期：2014-10-17 00:00:00

abstract：:How general anaesthetic drugs cause unconsciousness is a topic of ongoing clinical and scientific interest. It is becoming increasingly apparent that they disrupt cortical information processing, but the effects appear to depend on the spatial scale under investigation. In this study we investigated whether the intrav...

journal_title：Brain research

authors： Voss LJ,Baas CH,Hansson L,Li D,Sleigh JW

更新日期：2013-08-14 00:00:00

abstract：:Preferential uptake of dopamine occurred in mesocortical vs striatal synaptosomes obtained from acutely fighting isolated male ICR mice. Specifically, both Km and Vmax were significantly increased in the prefrontal cortex but not the caudate-putamen. The findings are similar to selective changes in mesocortical activi...

journal_title：Brain research

authors： Hadfield MG

更新日期：1981-10-05 00:00:00

abstract：:The neurotoxic compound 2,5-hexanedione (2,5-HD) causes an axonopathy characterized by the presence of neurofilament (NF)-containing enlargements in the preterminal segments of central and peripheral axons. The 2,5-HD axonopathy is a good model for human acquired and inherited giant axonal neuropathies. Recently, we r...

journal_title：Brain research

authors： Monaco S,Jacob J,Jenich H,Patton A,Autilio-Gambetti L,Gambetti P

更新日期：1989-07-10 00:00:00

abstract：:To investigate the role of the amygdala in central regulation of pancreatic exocrine secretion, the effects of electrolytic lesions on pancreatic secretion were studied in rats. Small bilateral electrolytic lesions in amygdaloid body restricted to basolateral, medial and central nuclei were produced. Eight days after ...

journal_title：Brain research

authors： Mine K,Tsuruta N,Nakai Y,Kataoka Y,Fujiwara M,Ueki S,Nakagawa T

更新日期：1985-08-05 00:00:00