Mesocortical vs nigrostriatal dopamine uptake in isolated fighting mice.

Abstract:

:Preferential uptake of dopamine occurred in mesocortical vs striatal synaptosomes obtained from acutely fighting isolated male ICR mice. Specifically, both Km and Vmax were significantly increased in the prefrontal cortex but not the caudate-putamen. The findings are similar to selective changes in mesocortical activity produced by various 'affective' stimuli as reported by others and they signal that higher DA emotive centers are importantly involved in agonistic behavior.

journal_name

Brain Res

journal_title

Brain research

authors

Hadfield MG

doi

10.1016/0006-8993(81)90954-9

subject

Has Abstract

pub_date

1981-10-05 00:00:00

pages

172-6

issue

1

eissn

0006-8993

issn

1872-6240

pii

0006-8993(81)90954-9

journal_volume

222

pub_type

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