Neurokinin-1 receptors and spinal cord control of blood pressure in spontaneously hypertensive rats.

abstract：:Neonatal treatment with gonadal steroids has been reported to alter morphological as well as functional development in various regions of the brain and spinal cord. Among the observed alterations are changes in numbers of neurons and in the organization and numbers of synapses. These regions have been found to be sexu...

journal_title：Brain research

authors： Wright LL,Smolen AJ

更新日期：1983-06-01 00:00:00

abstract：:The possibility of retinotopic organization of pathways of retinal fibers within the optic tract and the tectum of the frog was studied by selective labeling of the retinal fibers with horseradish peroxidase. Within the optic tract the pathways of the ventral, temporal and dorsal retinal fibers were ordered from the d...

journal_title：Brain research

authors： Fujisawa H,Watanabe K,Tani N,Ibata Y

更新日期：1981-02-09 00:00:00

abstract：:Movements of medium and large sized membranous organelles (0.5-1 microns in diameter) were visualized within segments of the crab walking leg nerve with Nomarski differential interference contrast optics and subjected to video contrast enhancement. Accessibility to the axoplasm was demonstrated by intra-axonal fluores...

journal_title：Brain research

authors： Moshiach S,Nelson TJ,Sanchez-Andres JV,Sakakibara M,Alkon DL

更新日期：1993-03-12 00:00:00

abstract：BACKGROUND:Metabolites involved in one-carbon metabolism (OCM) may predict cognitive prognosis in dementia. The link between OCM, apolipoprotein E (APOE), and DNA methylation creates a biologically plausible mechanism of interaction. AIM:To assess OCM metabolites as predictors of 5-year cognitive prognosis in patients...

journal_title：Brain research

authors： Hildre AS,Solvang SH,Aarsland D,Midtun Ø,McCann A,Ervik AO,Nygård O,Ueland PM,Nordrehaug JE,Giil LM

更新日期：2020-01-01 00:00:00

abstract：:Parkin Co-Regulated Gene (PACRG) is a novel gene that is oriented in a head-to-head array with parkin, and expression of the two genes is regulated by a shared bi-directional promoter. Mutations in parkin are the most common cause of early-onset autosomal recessive Parkinson's disease, however the function of PACRG an...

journal_title：Brain research

authors： Brody KM,Taylor JM,Wilson GR,Delatycki MB,Lockhart PJ

更新日期：2008-03-27 00:00:00

abstract：:Glioblastoma stem cells (GSCs) are thought to contribute to the diffuse invasiveness of malignant gliomas. Emerging evidence supports a role for a disintegrin and metalloproteinase 17 (ADAM17) in proteolytic ectodomain shedding of several EGFR-binding ligands, which subsequently activate PI3K/AKT and MEK/ERK pathways ...

journal_title：Brain research

authors： Chen X,Chen L,Chen J,Hu W,Gao H,Xie B,Wang X,Yin Z,Li S,Wang X

更新日期：2013-11-13 00:00:00

abstract：:Immunohistochemical localization of brain-derived neurotrophic factor (BDNF) in the monkey brain was investigated using a polyclonal anti-BDNF antibody produced in our laboratory. The antibody recognized a single band in monkey brain homogenates, and the estimated molecular weight was approximately 14 kDa, which corre...

journal_title：Brain research

authors： Kawamoto Y,Nakamura S,Kawamata T,Akiguchi I,Kimura J

更新日期：1999-03-13 00:00:00

abstract：:Phrenic afferents are capable of attenuating the phrenic motor response elicited by the intercostal-to-phrenic excitatory reflex in decerebrate, paralyzed cats. High spinal transection eliminates the attenuating effect of the bilateral phrenic-to-phrenic inhibitory reflex. These results indicate that although phrenic ...

journal_title：Brain research

authors： Speck DF

更新日期：1987-06-23 00:00:00

abstract：:The N-methyl-D-aspartate (NMDA) subtype of excitatory amino acid receptor is linked to an ion channel that is blocked by the phencyclidine analog N-(1-[thienyl]cyclohexyl)piperidine (TCP). Previous studies have shown that NMDA and glycine act together to increase the access of [3H]TCP to its binding site, presumably b...

journal_title：Brain research

authors： Hosford DA,Bonhaus DW,McNamara JO

更新日期：1990-05-21 00:00:00

abstract：:Single unit activities of Y, X and W cells were recorded in the cat lateral geniculate nucleus to study how their responses to stationary light spots change with the cortical EEG. The shift from desynchronized to synchronized EEG drastically suppressed W cell activities, depressed both transient and sustained componen...

journal_title：Brain research

authors： Sawai H,Morigiwa K,Fukuda Y

更新日期：1988-07-12 00:00:00

abstract：:In animals with retinal degeneration, the presence of activated microglial cells in the outer retina during the early stages of injury suggests that they may be involved in the ensuing photoreceptor cell death. In the following study, we investigated the effects of rat retina-derived microglial cells on a photorecepto...

journal_title：Brain research

authors： Roque RS,Rosales AA,Jingjing L,Agarwal N,Al-Ubaidi MR

更新日期：1999-07-31 00:00:00

abstract：:The ability of heterotopic noxious stimuli to inhibit the activity of dorsal horn convergent neurones was investigated in both intact anesthetized, and spinal unanesthetized rats. Forty-four convergent neurones in lumbar dorsal horn were recognized by their ability to respond to both noxious and non-noxious natural st...

journal_title：Brain research

authors： Cadden SW,Villanueva L,Chitour D,Le Bars D

更新日期：1983-09-19 00:00:00

abstract：:The present study examined the influences of dopamine (DA) receptor stimulation on enkephalin (Met5-enkephalin; ME) and tachykinin (substance P; SP) systems of basal ganglia of Sprague-Dawley rats, lesioned as neonates with 6-hydroxydopamine (6-OHDA). It has been proposed that the neonatal 6-OHDA-lesioned rat could se...

journal_title：Brain research

authors： Sivam SP

更新日期：1989-10-23 00:00:00

abstract：:In in vitro slices prepared from rat sensorimotor cortex, intracellular recordings were obtained from 107 layer V pyramidal neurons, subsequently injected with biocytin for morphological reconstruction. Of the 107 neurons, 59 (55.1%) were identified as adapting (45) or non-adapting (13) regular spiking neurons (RS), a...

journal_title：Brain research

authors： Franceschetti S,Guatteo E,Panzica F,Sancini G,Wanke E,Avanzini G

更新日期：1995-10-23 00:00:00

abstract：:In most cases obesity, a major risk factor for diabetes mellitus type 2 and other associated chronic diseases, is generated by excessive eating. For a better understanding of eating behavior, it is necessary to determine how it is modulated by factors such as the calorie content of food, satiety and gender. Twelve hea...

journal_title：Brain research

authors： Frank S,Laharnar N,Kullmann S,Veit R,Canova C,Hegner YL,Fritsche A,Preissl H

更新日期：2010-09-02 00:00:00

abstract：:The cholinergic nicotinic agonists (-)nicotine and lobeline were observed to partially inhibit whole-cell N-methyl-D-aspartate (NMDA)-induced responses in rat cortical neurons in culture. In addition we found that (-)nicotine, (+)nicotine, and lobeline, but not the nicotine metabolite (-)cotinine nor acetylcholine, we...

journal_title：Brain research

authors： Aizenman E,Tang LH,Reynolds IJ

更新日期：1991-06-14 00:00:00

abstract：:The motivational effects of exclusively peripheral or central opiate receptor blockade were studied using place conditioning. Place aversions were observed with intraventricular (i.c.v.) methylnaloxone (MN) in both naive (200-1000 ng) and morphine-dependent rats (50-500 ng). Subcutaneous MN (0.03-10 mg/kg) was ineffec...

journal_title：Brain research

authors： Hand TH,Koob GF,Stinus L,Le Moal M

更新日期：1988-12-06 00:00:00

abstract：:Spontaneous figure reversal of ambiguous patterns was analyzed in humans. A) With Necker-"cube"-like, or "drum"-like figures, having square or round shaped "front" and "rear" surfaces, and either large or small "depth", the perceptual intervals corresponding to both interpretations of "drum" were longer than those of ...

journal_title：Brain research

authors： Taddei-Ferretti C,Radilova J,Musio C,Santillo S,Cibelli E,Cotugno A,Radil T

更新日期：2008-08-15 00:00:00

abstract：:The pathological process in Alzheimer's disease (AD) involves amyloid beta (Abeta) deposition and neuronal cell degeneration. The neurotoxic Abeta peptide is derived from the amyloid precursor protein (APP), a member of a larger gene family including the amyloid precursor-like proteins, APLP1 and APLP2. The APP and AP...

journal_title：Brain research

authors： White AR,Reyes R,Mercer JF,Camakaris J,Zheng H,Bush AI,Multhaup G,Beyreuther K,Masters CL,Cappai R

更新日期：1999-09-25 00:00:00

abstract：:Trigeminal hyperalgesia frequently appears in diabetic neuralgia altering the transmission of orofacial sensory information. This study was designed to explore the effects of trigeminal hyperalgesia in streptozotocin-induced diabetes monitoring the expression of nitric oxide synthase in the trigeminal ganglion cells. ...

journal_title：Brain research

authors： Rodella L,Rezzani R,Corsetti G,Bianchi R

更新日期：2000-05-19 00:00:00

abstract：:The localization of the receptor for apamin, a specific toxin for one class of sensitive Ca2+-dependent K+ channel, was studied in rat brain using an in vitro autoradiographic technique. Radiolabeled monoiodoapamin binds specifically to rat brain sections with a high affinity (Kd = 25 pM) to a single class of sites. A...

journal_title：Brain research

authors： Mourre C,Hugues M,Lazdunski M

更新日期：1986-09-24 00:00:00

abstract：:Hydrocephalus with aqueduct stenosis was a consistent feature in mice which received a single intraperitoneal injection of 6-aminonicotinamide (6-AN) on day 5 postnatal. Chronological investigation revealed that 6-AN-treated mice had aqueductal obstruction with edematously swollen ependymal cells and spongy changes in...

journal_title：Brain research

authors： Aikawa H,Suzuki K

更新日期：1985-10-01 00:00:00

abstract：:10-fold higher doses in SW mice. Furthermore, cotreatment of 129/SvEv mice with morphine plus a low dose of naltrexone (ca. 0.1 microgram/kg) that markedly enhances and prolongs morphine's antinociceptive effects in SW mice did not enhance, and often attenuated6 h. The marked GM1-induced attenuation of morphine's anti...

journal_title：Brain research

authors： Crain SM,Shen K

更新日期：2000-02-21 00:00:00

abstract：:Rats with 6-hydroxydopamine (6-OHDA) lesions of the nigrostriatal pathway show enhanced locomotor and stereotyped behaviors when challenged with direct and indirect dopamine (DA) agonists due to the development of postsynaptic supersensitivity. To determine if this phenomenon generalizes to other motor behaviors, we h...

journal_title：Brain research

authors： Meloni EG,Davis M

更新日期：2000-10-06 00:00:00

abstract：:Electrical self-stimulation in the lateral hypothalamus was recorded in both hemispheres of 20 rats before and after making a lesion either by unilateral radiofrequency stimulation or by injection of N-methyl-D,L-aspartate into the region of the peduncular-pontine nucleus. For the animals which received the radiofrequ...

journal_title：Brain research

authors： Buscher W,Schugens M,Wagner U,Huston JP

更新日期：1989-05-22 00:00:00

abstract：:Traumatic brain injury (TBI) is a major public health problem with long-term neurobehavioral sequela. The evidences have revealed that TBI is a risk factor for later development of neurodegenerative disease and both the single and repetitive brain injury can lead to the neurodegeneration. But whether the effects of ac...

journal_title：Brain research

authors： Gao H,Han Z,Bai R,Huang S,Ge X,Chen F,Lei P

更新日期：2017-02-15 00:00:00

abstract：:The serotonin agonist 8-hydroxy-di-propylaminotetralin (8-OH-DPAT), injected systemically or directly into the medial preoptic area (MPOA), reduces the ejaculatory threshold in male rats. While 8-OH-DPAT has been characterized as an agonist at the 5-HT1A receptor, it also acts at other receptor sites including the dop...

journal_title：Brain research

authors： Matuszewich L,Lorrain DS,Trujillo R,Dominguez J,Putnam SK,Hull EM

更新日期：1999-02-27 00:00:00

abstract：:We consider a random synaptic pruning in an initially highly interconnected network. It is proved that a random network can maintain a self-sustained activity level for some parameters. For such a set of parameters a pruning is constructed so that in the resulting network each neuron/node has almost equal numbers of i...

journal_title：Brain research

authors： Turova TS

更新日期：2012-01-24 00:00:00

abstract：:Patches excised from fields CA1 and CA3 of the hippocampus were used to study AMPA receptor responses to repetitive application of brief pulses of agonist. AMPA receptors in field CA1 exhibited a larger degree of paired-pulse depression and a slower recovery rate from desensitization than those from CA3 patches. Respo...

journal_title：Brain research

authors： Arai A,Lynch G

更新日期：1996-04-15 00:00:00

abstract：:Systemic injection of kainic acid (KA) in adult rat elicits a pattern of neuronal pathology which exhibits several features of human temporal lobe epilepsy. KA-induced seizure activity is accompanied by the activation of the calcium-dependent protease calpain in limbic structures. In the present study, we evaluated th...

journal_title：Brain research

authors： Bi X,Chang V,Siman R,Tocco G,Baudry M

更新日期：1996-07-08 00:00:00