Abstract：
:The type and cell size of parvalbumin-immunoreactive (PV-Ir) neurones were examined in 14 postmortem brains from elderly control and Alzheimer-type dementia (ATD) patients with the aid of an image analyser. Morphological features of PV-Ir neurones suggested the existence of PV in the non-pyramidal interneurones in the cerebral cortex. A significant loss of PV-Ir cells was found in the frontal and temporal cortex in ATD. A significant reduction in the size of PV-Ir cells was also noted in the temporal cortex in ATD. These findings suggested that PV-Ir neurones in the cortex are affected in ATD.
journal_name
Brain Resjournal_title
Brain researchauthors
Arai H,Emson PC,Mountjoy CQ,Carassco LH,Heizmann CWdoi
10.1016/0006-8993(87)90974-7subject
Has Abstractpub_date
1987-08-18 00:00:00pages
164-9issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(87)90974-7journal_volume
418pub_type
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