Corticosterone delivery to the amygdala increases corticotropin-releasing factor mRNA in the central amygdaloid nucleus and anxiety-like behavior.

abstract：:Locally applied ciliary neurotrophic factor (CNTF) has a powerful effect on retrograde axonal reaction following facial nerve crush in neonatal rats. We examined whether it also exerts a strong effect on retrograde axonal reaction in young adult rats when administered subcutaneously. The dose was 1 mg/kg body weight, ...

journal_title：Brain research

authors： Ulenkate HJ,Gispen WH,Jennekens FG

更新日期：1996-04-22 00:00:00

abstract：:Short-term potentiation of extracellular field excitatory postsynaptic potentials (EPSP's) was investigated in the stratum radiatum of CA1 of the rat hippocampal slice in vitro. A presynaptic tetanus consisting of a single train of stimuli at 250 Hz evoked short-term potentiation (STP), but not long-term potentiation ...

journal_title：Brain research

authors： Anwyl R,Lee WL,Rowan M

更新日期：1988-08-30 00:00:00

abstract：:Mice were treated with dopamine (DA) receptor agonist and antagonist drugs: Agonists: (+/-)-SKF 38393 ((+/-)-1-phenyl-2,3,4, 5-tetrahydro-(1H)-3-benzazepine-7,8-diol) [DA D1-like]; bromocriptine, [DA D2 selective]; quinpirole, [DA D2/D3 preferring]; (+/-)-7-hydroxy-dipropylamino-tetralin (7-OH-DPAT), [DA D3/D2 preferr...

journal_title：Brain research

authors： Cho S,Duchemin AM,Neff NH,Hadjiconstantinou M

更新日期：1999-06-05 00:00:00

abstract：:Despite the significant advances that have been made in understanding the pathophysiology of cerebral ischemia on the cellular and molecular level, only one drug, the thrombolytic tissue plasminogen activator (rt-PA), is approved by the FDA for use in patients with acute ischemic stroke. Therefore, there is a critical...

journal_title：Brain research

authors： Maher P,Salgado KF,Zivin JA,Lapchak PA

更新日期：2007-10-10 00:00:00

abstract：:The presence of corticotropin releasing factor (CRF)-immunoreactive nerve fibers and cell bodies in the spinal cord is demonstrated. Immunopositive fibers were found in the lateral column of the white matter, in laminae I, V-VII, X, and in the intermediolateral column of the spinal cord. Complete transection of the sp...

journal_title：Brain research

authors： Merchenthaler I,Hynes MA,Vigh S,Shally AV,Petrusz P

更新日期：1983-09-26 00:00:00

abstract：:By use of the push-pull perfusion technique, release of neuronal cholecystokinin-like immunoreactivity (CCK-LI) from hypothalamus of owl monkeys was investigated in relation to an intragastric meal. In overnight fasted, halothane-anesthetized owl monkeys, levels of CCK-LI in the hypothalamic push-pull perfusate were b...

journal_title：Brain research

authors： Schick RR,Reilly WM,Roddy DR,Yaksh TL,Go VL

更新日期：1987-08-18 00:00:00

abstract：:This experiment was performed in order to examine several of the underlying mechanisms by which the septal area and adjacent regions regulate quiet biting attack behavior elicited from electrical stimulation of the hypothalamus in the cat. The results clearly indicate that stimulation of the septal area and anterior c...

journal_title：Brain research

authors： Brutus M,Shaikh MB,Siegel HE,Siegel A

更新日期：1984-09-24 00:00:00

abstract：:During functional spinal neural network activity motoneurons receive massive synaptic excitation and inhibition, and their membrane conductance increases considerably - they are switched to a high-conductance state. High-conductance states can substantially alter response properties of motoneurons. In the present stud...

journal_title：Brain research

authors： Grigonis R,Guzulaitis R,Buisas R,Alaburda A

更新日期：2016-10-01 00:00:00

abstract：:In this study, noradrenergic (NE) terminals in the dorsal raphe were identified by [3H]NE electron microscopic (EM) autoradiography. Lesioning of NE terminals by treatment with the selective catecholamine neurotoxin, 6-hydroxydopamine produced a marked decrease in NE-labelled terminals. [3H]5-HT EM autoradiography of ...

journal_title：Brain research

authors： Baraban JM,Aghajanian GK

更新日期：1981-01-05 00:00:00

abstract：:A possible role for neuropeptides in affective disorders is suggested by many investigators. Somatostatin-like immunoreactivity (SS-LI) and neuropeptide Y-like immunoreactivity (NPY-LI) concentrations are demonstrated to be reduced in cerebrospinal fluid from depressed patients. We have shown that long-term treatment ...

journal_title：Brain research

authors： Kakigi T,Maeda K

更新日期：1992-12-18 00:00:00

abstract：:Axon-to-myelin transfer of lipids precursors have been studied in the rabbit optic system by intraocular injection of [32P]orthophosphate, [14C]glycerol and [3H]glycerol. Choline and ethanolamine phosphoglycerides and myelin showed increasing [32P]-radioactivity between 7 and 21 days following injection, while [3H]- a...

journal_title：Brain research

authors： Ledeen RW,Haley JE

更新日期：1983-06-20 00:00:00

abstract：:Opioid modulation of calcium currents was studied in acutely dissociated rat basal forebrain neurons using the whole cell patch-clamp recording technique. The mu-opioid receptor agonist DAGO reversibly suppressed high-voltage activated calcium currents and slowed their rate of activation, while neither delta- nor kapp...

journal_title：Brain research

authors： Soldo BL,Moises HC

更新日期：1997-05-30 00:00:00

abstract：:Increases in extracellular potassium concentrations reliably increase burst rates in cultured fetal murine spinal cord networks. This effect could be mimicked by either blocking voltage-gated potassium conductances or facilitating excitatory synaptic interactions, but not by blocking specific calcium-dependent potassi...

journal_title：Brain research

authors： Rhoades BK,Gross GW

更新日期：1994-04-18 00:00:00

abstract：:Rats were given sham, cortical, or hippocampal lesions and sacrificed 7 or 28 days following surgery. Levels of norepinephrine, dopamine, and the major dopamine metabolites, 3,4-dihydroxyphenylacetic acid and homovanillic acid (HVA), were assayed in 3 brain regions. At day 7 there was a decrease in dopamine utilizatio...

journal_title：Brain research

authors： Springer JE,Isaacson RL

更新日期：1982-12-02 00:00:00

abstract：:The interaction of glutamatergic and dopamine neurotransmission is thought to have relevance to both the pathophysiology and pharmacotherapy of schizophrenia. For example, subanesthetic doses of the N-methyl-D-aspartate receptor (NMDA-R) antagonist ketamine induce schizophrenia-like behavioral effects in humans and bo...

journal_title：Brain research

authors： Miyamoto S,Mailman RB,Lieberman JA,Duncan GE

更新日期：2001-03-16 00:00:00

abstract：:Dissimilarity of the electroencephalogram (EEG) between the two hemispheres was characterized by cross-approximate entropy (C-ApEn), an information statistical parameter applicable to nonlinear, aperiodic signals. EEGs were recorded bipolarly with pairs of epidural electrodes in the left and right frontal cortices. Th...

journal_title：Brain research

authors： Hudetz AG

更新日期：2002-11-01 00:00:00

abstract：:Cytotoxic effects of L-glutamate and related compounds were investigated on rat glioma C6 cells in vitro. Within 12-24 h, addition of glutamate to the culture medium, resulted in degeneration of the C6 cells. The ED50 for glutamate-induced damage was about 4 mM. Seventeen structural analogues of glutamate, including a...

journal_title：Brain research

authors： Kato S,Higashida H,Higuchi Y,Hatakenaka S,Negishi K

更新日期：1984-06-15 00:00:00

abstract：:Glucose metabolism has been studied in the auditory cortex of human subjects with deafness of early onset, and compared to normal subjects with ears plugged. The metabolism in the auditory cortex and in the association auditory cortex was higher in deaf subjects than in normal subjects. This result is compared to simi...

journal_title：Brain research

authors： Catalán-Ahumada M,Deggouj N,De Volder A,Melin J,Michel C,Veraart C

更新日期：1993-10-01 00:00:00

abstract：:The two human brain beta-galactosidases were solubilized and fractionated by Sephadex G-200 gel filtration, free from each other. Substrate specificities of the two enzymes were examined for galactosylceramide, lactosyl-[N-stearoyl]ceramide, lactosyl-[N-lignoceroyl]ceramide, galactosyl-N-acetylgalactosaminyl-[N-stearo...

journal_title：Brain research

authors： Tanaka H,Suzuki K

更新日期：1977-02-18 00:00:00

abstract：:We examined the biochemical pathways whereby oral uridine-5'-monophosphate (UMP) increases membrane phosphatide synthesis in brains of gerbils. We previously showed that supplementing PC12 cells with uridine caused concentration-related increases in CDP-choline levels, and that this effect was mediated by elevations i...

journal_title：Brain research

authors： Cansev M,Watkins CJ,van der Beek EM,Wurtman RJ

更新日期：2005-10-05 00:00:00

abstract：:The organization and representation of conceptual knowledge in the brain remains a controversial issue in terms of both neuropsychological and imaging evidence. We report the results of a functional magnetic resonance study in which the role of the most debated dimensions (domain and feature type) was evaluated throug...

journal_title：Brain research

authors： Marques JF,Canessa N,Siri S,Catricalà E,Cappa S

更新日期：2008-02-15 00:00:00

abstract：:A large body of evidence shows that methamphetamine (METH) causes sustained damage to the brain in animal models and human METH users. In chronic users there are indications of cognitive and motor deficits. Striatal neuropeptides are in a position to modulate the neurochemical effects of METH and consequently striatal...

journal_title：Brain research

authors： Afanador L,Mexhitaj I,Diaz C,Ordonez D,Baker L,Angulo JA

更新日期：2013-05-13 00:00:00

abstract：:A total of 183 nucleus basalis of Meynert (NBM) neurons were recorded in a monkey performing a delayed response task. Significant changes in discharge rate were detected in 74% of the NBM cells sampled with most responses occurring in the choice (64%) or the reward (67%) epochs of the task. Neuronal responses in the c...

journal_title：Brain research

authors： Richardson RT,DeLong MR

更新日期：1986-12-10 00:00:00

abstract：:Serotonin 1A (5HT1A) receptor agonists have shown neuroprotective properties in different models of central nervous system injury. Activation of neuronal 5HT1A receptors appears to be involved in the neuroprotective effects. It remains to be elucidated if astroglial cells are responsive to the 5HT1A neuroprotective ef...

journal_title：Brain research

authors： Ramos AJ,Rubio MD,Defagot C,Hischberg L,Villar MJ,Brusco A

更新日期：2004-12-31 00:00:00

abstract：:We examined the effect of the molarless condition on the dendritic spines of hippocampal pyramidal cells in SAMP8 mice in comparison to its effect on learning ability in a maze test. The molarless condition caused a decrease in the number of the spines of CA1 pyramidal cells only in the aged mice showing a reduced lea...

journal_title：Brain research

authors： Kubo KY,Iwaku F,Watanabe K,Fujita M,Onozuka M

更新日期：2005-09-28 00:00:00

abstract：:Autoradiographic analysis of [(35)S]GTPgammaS binding was used to investigate functional activation of dopamine receptors in rat striatum. Dopamine-stimulated [(35)S]GTPgammaS binding was observed with a maximal increase of 38% over basal activity. A similar stimulatory response was obtained with the D(2) agonist quin...

journal_title：Brain research

authors： He L,Di Monte DA,Langston JW,Quik M

更新日期：2000-12-01 00:00:00

abstract：:The role of the cerebellum and the red nucleus in the conditioned eyeblink response was assessed, using a combination of reversible lesions and multiple-unit extracellular recording in the awake, behaving rabbit. Lesion, recording, and stimulation experiments have indicated that both of these structures are involved i...

journal_title：Brain research

authors： Chapman PF,Steinmetz JE,Sears LL,Thompson RF

更新日期：1990-12-24 00:00:00

abstract：:In order to explore the anatomical nature of the inhibitory GABAergic control of cerebral serotonergic neurons exerted at the level of the anterior raphé cells in the rat, we have studied the effect of GABA agonist agents (given systemically or infused locally into the raphé dorsalis or medianus) on cerebral 5-hydroxy...

journal_title：Brain research

authors： Nishikawa T,Scatton B

更新日期：1985-04-01 00:00:00

abstract：:A small, unilateral, penetrating wound was placed in the dorsolateral portion of the lumbosacral spinal cord in immature rats. Although this wound did not extend into the central canal area, some cells forming the walls of this canal underwent proliferative activity as demonstrated by [3H]thymidine autoradiography. Th...

journal_title：Brain research

authors： Gilmore SA,Leiting JE

更新日期：1980-11-10 00:00:00

abstract：:Surgical microscopy and electrophysiological techniques were used to standardize the nomenclature for the pudendal nerve and sacral plexus according to their somatic axonal composition in the male rat. We conclude that the pudendal nerve is the segment running from the L6-S1 trunk to the sacral plexus, carrying effere...

journal_title：Brain research

authors： Pacheco P,Camacho MA,García LI,Hernández ME,Carrillo P,Manzo J

更新日期：1997-07-25 00:00:00