Molarless-induced changes of spines in hippocampal region of SAMP8 mice.

abstract：:Although there are indications of growth in the size and myelination of the rat corpus callosum during adulthood, it is not known how long this growth continues. In addition, the potential for age-related changes in these measures to affect the sex differences seen in adulthood has not been examined. Here the size of ...

journal_title：Brain research

authors： Yates MA,Juraska JM

更新日期：2007-04-20 00:00:00

abstract：:Cocaine (25 mg/kg i.p.) produces analgesia in the rat within 5 min and for a duration of 90 min as determined by the formalin test or for 30 min as determined by the hot plate test. Cocaine analgesia is unaffected by doses of naloxone that are sufficient to attenuate morphine analgesia in both tests. Chlorpromazine (3...

journal_title：Brain research

authors： Lin Y,Morrow TJ,Kiritsy-Roy JA,Terry LC,Casey KL

更新日期：1989-02-13 00:00:00

abstract：:Previous studies have shown behavioral changes in pre- and postnatal rats exposed to morphine before and during gestation. The present study has attempted to discover morphological correlates of these changes in the fetal rat spinal cord. Pregnant Wistar rats were injected subcutaneously on days 12-18 of gestation wit...

journal_title：Brain research

authors： Kirby ML

更新日期：1980-11-24 00:00:00

abstract：:Instructions are an inextricable, yet poorly understood aspect of modern human life. In this paper we propose that instruction implementation and following can be understood as fast Hebbian learning in prefrontal cortex, which trains slower pathways (e.g., cortical-basal ganglia pathways). We present a computational m...

journal_title：Brain research

authors： Ramamoorthy A,Verguts T

更新日期：2012-02-23 00:00:00

abstract：:Dendritic architecture and distribution of dendritic protrusions were studied on Golgi-impregnated neurons in the medial preoptic area (MPOA) of infant rats (7 and 20 days old), of animals at puberty (34 days old) and of postpubertal rats (90 days old) using computerized image analysis. The protrusions showed a peak d...

journal_title：Brain research

authors： Geröcs K,Réthelyi M,Halász B

更新日期：1986-04-01 00:00:00

abstract：:Recently developed antisera selective for angiotensin Type 2 (AT2) receptors were used to localize AT2 receptors in rat brain by immunohistochemistry. While the results from these experiments were largely consistent with previous autoradiographic and radioligand binding analyses of AT2 receptor populations in brain, t...

journal_title：Brain research

authors： Reagan LP,Flanagan-Cato LM,Yee DK,Ma LY,Sakai RR,Fluharty SJ

更新日期：1994-10-31 00:00:00

abstract：:The density of binding sites for excitatory amino acids in the hippocampus of SDAT (senile dementia of the Alzheimer type) patients has been investigated. This was compared to that found in younger and old non-dement cases. In the SDAT hippocampi there was a significant decrease in the glutamate and kainate binding. T...

journal_title：Brain research

authors： Represa A,Duyckaerts C,Tremblay E,Hauw JJ,Ben-Ari Y

更新日期：1988-08-09 00:00:00

abstract：:The distribution of carbonic anhydrase (CA) activity was determined histochemically using Hansson's cobalt phosphate method in cross-sections of peripheral nerves from rats. As the studied nerves contain either efferent, proprioceptive or exteroceptive myelinated fibres, our survey particularly focused on the question...

journal_title：Brain research

authors： Szabolcs MJ,Kopp M,Schaden GE

更新日期：1989-07-17 00:00:00

abstract：:Echo-planar magnetic resonance imaging (EP-MRI), which is novel variant of MRI, is thought to have antidepressant properties in humans and animal models. Using the forced swimming test (FST), we investigated which monoaminergic system in mice is affected by EP-MRI. The short- and long-term effects of EP-MRI on immobil...

journal_title：Brain research

authors： Aksoz E,Aksoz T,Bilge SS,Ilkaya F,Celik S,Diren HB

更新日期：2008-10-21 00:00:00

abstract：:The distribution of avian pancreatic polypeptide (APP)-like immunoreactivity (APP-IR) in the chicken retina was investigated by means of immunohistochemistry. The observation from frozen sections showed that APP-IR is localized in the stratified amacrine cells of the first sublayer. Examination of whole-mounts reveale...

journal_title：Brain research

authors： Katayama Y,Kiyama H,Arai Y,Tohyama M

更新日期：1984-09-17 00:00:00

abstract：:Apart from the essential role of 1alpha,25-dihydroxyvitamin D3 in calcium and phosphorus metabolism, this compound and its analogs are involved in regulating the functions of the central nervous and immune systems. Active forms of vitamin D3 have been reported to stimulate neurotrophin gene expression and to prevent n...

journal_title：Brain research

authors： Tetich M,Dziedzicka-Wasylewska M,Kuśmider M,Kutner A,Leśkiewicz M,Jaworska-Feil L,Budziszewska B,Kubera M,Myint AM,Basta-Kaim A,Skowroński M,Lasoń W

更新日期：2005-03-28 00:00:00

abstract：:Insulin-like growth factor (IGF) II receptors were studied in human adult brain by using autoradiography with [125I]IGF-II. Receptors were found to be widely distributed throughout all neuronal regions. The highest densities were found in plexus choroideus, granular layer of the cerebellar cortex, gyrus dendatus and p...

journal_title：Brain research

authors： Wilczak N,De Bleser P,Luiten P,Geerts A,Teelken A,De Keyser J

更新日期：2000-04-28 00:00:00

abstract：:The adaptation to hypoxia and hypercapnia requires the activation of several anatomical structures along the neuraxis. In this study, using Fos immunoreactivity, we sought to map neuronal populations involved in chemoreflex networks activated during the responses to moderate hypoxia (O(2) 11%), and hypercapnia (CO(2) ...

journal_title：Brain research

authors： Berquin P,Bodineau L,Gros F,Larnicol N

更新日期：2000-02-28 00:00:00

abstract：:Performance on object recognition and object placement memory tasks was evaluated after a short-dosing model of methamphetamine (MA) regime and monoamines and metabolites were measured post-testing. Adult male rats received three injections of 10 mg/kg at 2-h intervals. In striatum DA and 5-HT were depleted by 65% and...

journal_title：Brain research

authors： Bisagno V,Ferguson D,Luine VN

更新日期：2002-06-14 00:00:00

abstract：:We have examined the soma diameters and distribution of catecholaminergic (CA) cells in human retinae, by using an antibody to tyrosine hydroxylase (TH), the rate limiting enzyme in the production of catecholamines. TH-immunoreactivity was detected in two classes of cells (CA1 and CA2 cells). CA1 cells had relatively ...

journal_title：Brain research

authors： Mitrofanis J,Provis JM

更新日期：1990-09-10 00:00:00

abstract：:We evaluated the effects of glycine exposure upon CA1-evoked response in the rat hippocampal slice. Exposure to 10 mM glycine for 16 min produced rapid neuronal firing and increased orthodromic population spike (PS), followed by loss of CA1 neural transmission. Upon recovery, CA1 orthodromic and antidromic PS regained...

journal_title：Brain research

authors： Wallis RA,Panizzon KL,Nolan JP

更新日期：1994-11-21 00:00:00

abstract：:Injections of HRP throughout the upper tectal strata led in 4 cases to the appearance of retrogradely labeled neurons within n.isthmi ventralis, contralateral to the experimental side. An additional case proved that this projection courses through the ventral supraoptic commissure. This is the first description of a c...

journal_title：Brain research

authors： Martínez S,Puelles L

更新日期：1989-02-27 00:00:00

abstract：:The effects of the epileptogenic agent, penicillin, on excitatory and inhibitory postsynaptic potentials (EPSPs and IPSPs) were studied in the hippocampal in vitro slice preparation. The actions of penicillin were compared to those of bicuculline, an antagonist of gamma-aminobutyric acid. Neither substance enhanced mo...

journal_title：Brain research

authors： Schwartzkroin PA,Prince DA

更新日期：1980-02-03 00:00:00

abstract：:Na-independent [3H]glutamate binding to rat hippocampal membranes increases progressively as a function of age. The increased binding represents an increased number of binding sites without changes in their apparent affinity for glutamate. However, [3H]glutamate binding, measured with a saturating concentration of cal...

journal_title：Brain research

authors： Baudry M,Arst DS,Lynch G

更新日期：1981-10-26 00:00:00

abstract：:Myelin, the lipid-rich sheath that insulates axons to facilitate rapid conduction of action potentials, is an evolutionary innovation of the jawed-vertebrate lineage. Research efforts aimed at understanding the molecular mechanisms governing myelination have primarily focused on rodent models; however, with the advent...

journal_title：Brain research

authors： Ackerman SD,Monk KR

更新日期：2016-06-15 00:00:00

abstract：:Retinoic acid (RA), which is an important modulator of brain development, neural cell proliferation, neurite outgrowth, and synaptic plasticity, is regulated via changes in RA receptors. The pattern of RA receptor changes in the rat cerebral cortex and white matter during postnatal development has not been extensively...

journal_title：Brain research

authors： Jiang W,Wen EY,Gong M,Shi Y,Chen L,Bi Y,Zhang Y,Liu YF,Chen J,Qu P,Liu YX,Wei XP,Li TY

更新日期：2011-03-25 00:00:00

abstract：:Distribution of somatostatin (SS) immunoreactivity was observed in the preoptic-anterior hypothalamus (PO-AH) of the female rat brain. Six specific rabbit antibodies A (SS-14), B (SS-28), C (SS-28 complete), D (SS 14 and SS-28 both), E (SS preprohormone) and F (GHRH) were used for immunostaining using Avidin-Biotin Co...

journal_title：Brain research

authors： Bhatnagar M

更新日期：2001-05-11 00:00:00

abstract：:In adult female rats, estrogen receptor (ER) activation, particularly of ERbeta, promotes hippocampal neurogenesis. We previously reported that extranuclear ERbeta immunoreactivity (ir) in adult rats is on cellular profiles in or near the granule cell layer, which is the location of newly generated cells. During devel...

journal_title：Brain research

authors： Herrick SP,Waters EM,Drake CT,McEwen BS,Milner TA

更新日期：2006-11-22 00:00:00

abstract：:This study examined the spatial organization of corticotropin-releasing factor (CRF) immunopositive climbing fibers in the mouse cerebellum by whole mount immunohistochemistry. A striking pattern of parasagittal stripes of CRF staining was revealed. Cryosections of whole mount CRF stained cerebellum showed that anti-C...

journal_title：Brain research

authors： Sawada K,Fukui Y,Hawkes R

更新日期：2008-07-30 00:00:00

abstract：:Tyrosine hydroxylase immunohistochemical examination of the mesencephalon of severely parkinsonian MPTP-treated macaque fascicularis monkeys revealed a marked loss of substantia nigra pars compacta (SNc) neurons in both medial and central portions of the nucleus with a relative sparing of neurons in the dorsal-most po...

journal_title：Brain research

authors： Schneider JS,Yuwiler A,Markham CH

更新日期：1987-05-12 00:00:00

abstract：:Employing a paired-watering procedure to control for differential fluid intake confounds, adult male rats were exposed in the home cage to water containing 100 ppm cadmium chloride, or a control solution containing no added cadmium chloride. On Day 61 of exposure to their respective watering regimens, half the animals...

journal_title：Brain research

authors： Nation JR,Livermore CL,Bratton GR

更新日期：1995-12-08 00:00:00

abstract：:The feedback effect of activity of area 21a on orientation maps of areas 17 and 18 was investigated in cats using intrinsic signal optical imaging. A spatial frequency-dependent decrease in response amplitude of orientation maps to grating stimuli was observed in areas 17 and 18 when area 21a was inactivated by local ...

journal_title：Brain research

authors： Huang L,Chen X,Shou T

更新日期：2004-02-20 00:00:00

abstract：:Histochemical investigation by means of light and electron microscopy revealed the presence of dipeptidylpeptidase IV activity in Meissner corpuscles of macaque glabrous skin. The enzyme activity was found in fibroblast-like cells forming an incomplete capsule around the Meissner corpuscle. Distinct electron-dense rea...

journal_title：Brain research

authors： Dubový P

更新日期：1988-09-27 00:00:00

abstract：:Lavender belongs to the family Labiatae and has a variety of cosmetic uses as well as therapeutic purposes in herbal medicine. The present study was conducted to evaluate the protective effect of lavender oil against brain edema and its possible mechanisms in an experimental model of stroke. Under Laser-Doppler Flowme...

journal_title：Brain research

authors： Vakili A,Sharifat S,Akhavan MM,Bandegi AR

更新日期：2014-02-22 00:00:00

abstract：:Our recent results showed that angiotensin II or III (AII, AIII) microinjected into the zona incerta (ZI) significantly increased water intake. The most effective doses of AII and AIII were also defined. The two neuropeptides had their effects differently on drinking via different receptors. AII bound to AT(1) that wa...

journal_title：Brain research

authors： Bagi EE,Fekete E,Bányai D,Lénárd L

更新日期：2004-03-26 00:00:00