Autoradiographic analysis of dopamine receptor-stimulated [(35)S]GTPgammaS binding in rat striatum.

abstract：:We have evaluated changes in the expression of neurotrophin-3 (NT-3) and its tyrosine kinase C (TrkC) receptor in the neuromuscular system as a result of voluntary physical activity. We assessed changes in the mRNAs and proteins for NT-3 and TrkC in the lumbar spinal cord and associated soleus muscle following 3 and 7...

journal_title：Brain research

authors： Ying Z,Roy RR,Edgerton VR,Gómez-Pinilla F

更新日期：2003-10-10 00:00:00

abstract：:The status of blood-brain barrier (BBB) permeability was investigated in the twitcher, an authentic murine model of globoid cell leukodystrophy (GLD, Krabbe disease) and cuprizone-intoxicated mice. Although extensive demyelination was noted in the CNS of both mice and additionally, macrophage infiltration was pronounc...

journal_title：Brain research

authors： Kondo A,Nakano T,Suzuki K

更新日期：1987-11-03 00:00:00

abstract：:The relationship between placental antigen X-P2 (PAX)-immunoreactive glomeruli and intensely acetylcholinesterase-reactive (IAE) patchy regions was evaluated by comparison of neighboring cryostat sections of the rat olfactory bulb. Both groups of distribution show similar necklace patterns. Each IAE region consists of...

journal_title：Brain research

authors： Shinoda K,Ohtsuki T,Nagano M,Okumura T

更新日期：1993-07-30 00:00:00

abstract：:In situ hybridization (ISH) is an essential technique for mapping gene expression in the brain. Although many ISH protocols provide for quantitative analysis of individual mRNAs in different brain regions or across experimental conditions, this technique has lacked the necessary standardization for quantitative compar...

journal_title：Brain research

authors： Broide RS,Trembleau A,Ellison JA,Cooper J,Lo D,Young WG,Morrison JH,Bloom FE

更新日期：2004-03-12 00:00:00

abstract：:Some afferent fibers from the pudendal nerve of the female cat were stimulated by pressing on the perineal skin, the vagina or the uterine cervix. Three different types of skin mechanoreceptors were found: (1) with low threshold (< 20 mg) and slow-adapting discharges; (2) with high threshold (0.1-0.5 g) and slow-adapt...

journal_title：Brain research

authors： Cueva-Rolón R,Muñoz-Martínez EJ,Delgado-Lezama R,Raya JG

更新日期：1994-08-29 00:00:00

abstract：:Choline acetyltransferase (ChAT) and glutamic acid decarboxylase (GAD) activities were measured in various visual structures of the pigeon brain after long-term monocular deprivation followed by short-term binocular presence or absence of light stimulation. The short-term phase (45 min) was coupled with a 2-deoxygluco...

journal_title：Brain research

authors： Bagnoli P,Burkhalter A,Vischer A,Henke H,Cuénod M

更新日期：1982-09-16 00:00:00

abstract：:High molecular weight complexes of aminoacyl-tRNA synthetases isolated from rat brain catalyze the formation of glutamyl-tRNA with an initial lag time of the order of 1 min, as previously reported for the formation of glutamyl-tRNA and glutaminyl-tRNA catalyzed by similar complexes from bovine brain (Vadeboncoeur and ...

journal_title：Brain research

authors： Lacoste L,Hertz L,Lapointe J

更新日期：1986-07-01 00:00:00

abstract：:Male laboratory rats were raised in two colonies, each of 27 rats, and then given intraventricular injections of the norepinephrine neurotoxin 6-hydroxydopamine (6-OHDA) or the serotonin neurotoxin 5,6-dihydroxytryptamine (5,6-DHT) or saline. They were then returned to their enclosure and behavior during the next 50 d...

journal_title：Brain research

authors： Ellison G

更新日期：1976-02-13 00:00:00

abstract：:PGP 9.5 is a new cytoplasmic neuron-specific protein structurally and immunologically distinct from neuron-specific enolase. A specific antiserum has now shown that this protein is widely distributed in vertebrate brains and is also present in cells of the human diffuse neuroendocrine system. PGP 9.5 appears to be old...

journal_title：Brain research

authors： Thompson RJ,Doran JF,Jackson P,Dhillon AP,Rode J

更新日期：1983-11-14 00:00:00

abstract：:We have studied in adult rats bearing a unilateral nigral lesion the effect of nigral grafts into the striatum on behavioral supersensitivity induced by chronic treatment of L-DOPA (100 mg/kg i.p.) plus benserazide (50 mg/kg i.p.). Repeated administration of L-DOPA increases contraversive circling. In rats without gra...

journal_title：Brain research

authors： Gaudin DP,Rioux L,Bédard PJ

更新日期：1990-01-01 00:00:00

abstract：:Subnanomolar concentrations of melatonin inhibit cyclic AMP and cyclic GMP accumulation in neonatal rat anterior pituitary stimulated in vitro with luteinizing-hormone releasing-hormone. Melatonin also inhibited forskolin-stimulated cyclic AMP accumulation in pars tuberalis. Inhibition of cyclic AMP accumulation is sp...

journal_title：Brain research

authors： Vanĕcek J,Vollrath L

更新日期：1989-12-25 00:00:00

abstract：:Mutations in two genes, alpha-synuclein and parkin, have been identified as some rare causes for familial Parkinson's disease (PD). alpha-Synuclein and parkin protein have subsequently been identified in Lewy bodies (LB). To gain further insight into the pathogenesis of PD we investigated the role of neurofilament lig...

journal_title：Brain research

authors： Rahner N,Holzmann C,Krüger R,Schöls L,Berger K,Riess O

更新日期：2002-09-27 00:00:00

abstract：:Myelin basic proteins (MBP) obtained from bovine, guinea pig and human nervous tissues exhibited hemagglutinating activity for erythrocytes of several animal species. The activity to each erythrocyte was actually equal among the 3 MBPs. With bovine MBP and chicken erythrocytes, the hemagglutinating activity did not re...

journal_title：Brain research

authors： Ikeda K,Yamamoto T

更新日期：1985-03-11 00:00:00

abstract：:Dapsone (4,4'-diaminodiphenylsulfone) is employed in the chemotherapy against leprosy. Dapsone also prevents neuronal damage induced by glutamate agonists. As glutamate excitotoxicity is implicated in the damage after ischemia, we tested the ability of dapsone to prevent ischemic injury in a model of permanent middle ...

journal_title：Brain research

authors： Ríos C,Nader-Kawachi J,Rodriguez-Payán AJ,Nava-Ruiz C

更新日期：2004-03-05 00:00:00

abstract：:In pentobarbital-anesthetized rats, responses of single neurons in ventrolateral orbital cortex (VLO) to noxious visceral (colorectal distension, CRD) and cutaneous stimulation were recorded. Of 71 neurons identified on the basis of spontaneous activity, 44 responded to CRD. CRD caused inhibition of neuronal activity ...

journal_title：Brain research

authors： Follett KA,Dirks B

更新日期：1995-01-16 00:00:00

abstract：:In freely-moving rats treated with a combination of reserpine (10 mg/kg, i.p.) and scopolamine (5 mg/kg, i.p.), neocortical low voltage fast activity (LVFA) associated with continuous multiunit activity (MUA) was abolished and replaced by 2-6 Hz large irregular slow activity (LISA) above 1.5 mV associated with a burst...

journal_title：Brain research

authors： Dringenberg HC,Vanderwolf CH

更新日期：1996-07-29 00:00:00

abstract：:The cholinergic presynaptic terminals of Torpedo electric organ have been examined morphometrically following stimulation by KCI and sucrose. The objective was to confirm correlations predicted by the vesicle hypothesis between miniature end-plate potentials (MEPPs) and morphometric changes in terminal ultrastructure....

journal_title：Brain research

authors： Fox GQ,Kriebel ME

更新日期：1997-04-25 00:00:00

abstract：:The electrophysiological characteristics of physiologically typed L7 and S1 dorsal root ganglion (DRG) cells have been studied in the cat by intracellular recording. The injection of the fluorescent dye Lucifer Yellow has enabled us to study the morphology of these neurons. Our results show that over the entire range ...

journal_title：Brain research

authors： Cameron AA,Leah JD,Snow PJ

更新日期：1986-01-01 00:00:00

abstract：:To study the regulation of hypothalamic vasopressin (VP) and oxytocin (OT) gene expression in relation to the development of hypertension, levels of VP mRNA and OT mRNA were determined in spontaneously hypertensive rats (SHR). Differences in VP and OT mRNA content of the supraoptic nucleus (SON) and paraventricular nu...

journal_title：Brain research

authors： van Tol HH,van den Buuse M,de Jong W,Burbach JP

更新日期：1988-12-01 00:00:00

abstract：:Thermoregulation is a complex intercommunicative function requiring coordination between core body temperature (CBT), the central nervous system, and peripheral vasculature. In menopausal women, dysregulation of thermoregulatory mechanisms leads to hot flushes and night sweats. A previous study in ovariectomized (OVX)...

journal_title：Brain research

authors： Pawlyk AC,Cosmi S,Alfinito PD,Maswood N,Deecher DC

更新日期：2006-12-06 00:00:00

abstract：:Despite the significant advances that have been made in understanding the pathophysiology of cerebral ischemia on the cellular and molecular level, only one drug, the thrombolytic tissue plasminogen activator (rt-PA), is approved by the FDA for use in patients with acute ischemic stroke. Therefore, there is a critical...

journal_title：Brain research

authors： Maher P,Salgado KF,Zivin JA,Lapchak PA

更新日期：2007-10-10 00:00:00

abstract：:The present study was undertaken to disclose temporal changes in the distribution of Fos-like immunoreactive (-IR) neurons in the trigeminal subnucleus caudalis (SpVc), one of the important relay nuclei for processing the nociceptive information from the oro-facial regions, following induction of experimental tooth mo...

journal_title：Brain research

authors： Aihara Y,Maeda T,Hanada K,Wakisaka S

更新日期：1999-02-20 00:00:00

abstract：:Recently mutations in ubiquilin-2 were identified in patients with amyotrophic lateral sclerosis (ALS) and ALS/dementia providing direct evidence for the importance of this protein in neurodegenerative diseases. Histological studies have suggested that ubiquilin-1/-2 are associated with various pathological inclusions...

journal_title：Brain research

authors： Rutherford NJ,Lewis J,Clippinger AK,Thomas MA,Adamson J,Cruz PE,Cannon A,Xu G,Golde TE,Shaw G,Borchelt DR,Giasson BI

更新日期：2013-08-02 00:00:00

abstract：:We previously reported the presence of Erk2 type mitogen-activated protein kinase (MAPK) and enrichment of its substrates in the post-synaptic density (PSD) fraction, and suggested a role for MAPK in the synaptic transmission and its modulation [Suzuki, T., Okumura-Noji, K., Nishida, E., ERK2-type mitogen-activated pr...

journal_title：Brain research

authors： Suzuki T,Mitake S,Murata S

更新日期：1999-09-04 00:00:00

abstract：:Chronically epileptic male adult rats in the pilocarpine model of temporal lobe epilepsy (TLE), exhibited gross expansion of abdominal fat mass and significant weight gain several months after induction of status epilepticus (SE) when compared to control rats. We hypothesized that epileptogenesis can induce molecular ...

journal_title：Brain research

authors： Ruiz N,Pacheco LF,Farrell B,Cox CB,Ermolinsky BS,Garrido-Sanabria ER,Nair S

更新日期：2011-12-02 00:00:00

abstract：:A method to study the protein binding patterns of trace elements in human cerebrospinal fluid (CSF) is described. Proteins in CSF samples were separated by size exclusion chromatography combined with high performance liquid chromatography (SEC-HPLC). The column was calibrated to separate proteins in the molecular weig...

journal_title：Brain research

authors： Gellein K,Roos PM,Evje L,Vesterberg O,Flaten TP,Nordberg M,Syversen T

更新日期：2007-10-12 00:00:00

abstract：:Recent studies have confirmed the presence of insulin receptors in the rat brain although their function has still not been well defined. The present study explores the possibility that insulin receptors in the brain can alter or contribute to central neurotransmission. Insulin caused a dose-dependent inhibition of hi...

journal_title：Brain research

authors： Palovcik RA,Phillips MI,Kappy MS,Raizada MK

更新日期：1984-08-20 00:00:00

abstract：:The effects of 17beta-estradiol (17betaE2) on spontaneous and excitatory amino acid (EAA) induced nucleus tractus solitarius (NTS) neuronal activity were investigated by electrophysiological and immunohistochemical experiments in ovariectomized female Sprague-Dawley rats. Out of 62 NTS neurons tested, 42 were inhibite...

journal_title：Brain research

authors： Xue B,Hay M

更新日期：2003-06-20 00:00:00

abstract：:Muscarinic and NMDA receptors contribute to post-traumatic hypersensitivity to secondary ischemia. However, the effect of these receptor antagonists on behavior and CA1 neuronal death after traumatic brain injury (TBI) with acute (1 h after TBI) forebrain ischemia has not been systematically assessed. We examined cogn...

journal_title：Brain research

authors： Jenkins LW,Lu Y,Johnston WE,Lyeth BG,Prough DS

更新日期：1999-01-30 00:00:00

abstract：:The cellular origin and degree of collateralization of the subthalamostriatal, subthalamonigral and subthalamopallidal projections in the squirrel monkey (Saimiri sciureus) were studied using lectin-conjugated horseradish peroxidase (WGA-HRP), Nuclear yellow (NY) and Fast blue (FB) as retrograde tracers. In a first ex...

journal_title：Brain research

authors： Parent A,Smith Y

更新日期：1987-12-15 00:00:00