Voluntary exercise increases neurotrophin-3 and its receptor TrkC in the spinal cord.

abstract：:Immunohistochemistry for calcitonin gene-related peptide (CGRP), tyrosine hydroxylase and calbindin D-28k was performed on the glossopharyngeal and vagal ganglia in mCOUP-TFI knockout mice to know the effect of its deficiency on different types of primary sensory neurons. In wild type and heterozygous mice, the glosso...

journal_title：Brain research

authors： Ichikawa H,Lin SC,Tsai SY,Tsai MJ,Sugimoto T

更新日期：2004-07-16 00:00:00

abstract：:Monkeys can gradually increase or decrease the amplitude of the segmentally mediated spinal stretch reflex (SSR) without change in initial muscle length or background EMG activity. Both increase (under the SSR increases mode) and decrease (under the SSR decreases mode) occur slowly, progressing steadily over weeks. Th...

journal_title：Brain research

authors： Wolpaw JR

更新日期：1983-11-14 00:00:00

abstract：:Nerve injury was produced by application of dry ice to the common peroneal nerve. After 20 weeks, muscle-spindle primary endings responded normally to stretch and the spindles were found to have a fully functional fusimotor innervation. ...

journal_title：Brain research

authors： Scott JJ

更新日期：1985-11-25 00:00:00

abstract：:(1) Input conductances of giant interneurons in the isolated spinal cord of lampreys were measured with two separate intracellular electrodes. Bath applications of 0.4--3 mM beta-alanine and taurine produced large, reversible conductance increases which were Cl-dependent. (2) Strychnine at 1--2.5 microM might be a com...

journal_title：Brain research

authors： Homma S

更新日期：1979-09-14 00:00:00

abstract：:The results showed that the development of seizures (pentylenetetrazole, PTZ-induced kindling; PTZ was administered to rats at a subconvulsive dose of 35mg/kg three times a week, i.p.) was accompanied by a progressive recruitment of limbic structures and a characteristic pattern of changes in the brain tissue concentr...

journal_title：Brain research

authors： Maciejak P,Szyndler J,Turzyńska D,Sobolewska A,Bidziński A,Kołosowska K,Płaźnik A

更新日期：2010-06-25 00:00:00

abstract：:The neuropeptide neurotensin (NT) has been shown to modulate mesolimbic dopaminergic activity. Neurotensin injected into the VTA produces motor stimulation and release of dopamine in the nucleus accumbens. In contrast, when neurotensin is administered into the nucleus accumbens, it produces neuroleptic-like effects su...

journal_title：Brain research

authors： Robledo P,Maldonado R,Koob GF

更新日期：1993-09-17 00:00:00

abstract：:Immunofluorescence on primary dissociated rat neuronal cultures (cortical, hippocampal, and cerebellar) and organotypic hippocampal cultures was used to investigate the pattern of distribution of cell-surface amyloid protein (APP). Antibodies directed against the extracellular (N-terminal) portion of APP or against th...

journal_title：Brain research

authors： Storey E,Beyreuther K,Masters CL

更新日期：1996-10-07 00:00:00

abstract：:The retinotopic organization of the expanded projection to the ipsilateral colliculus was studied electrophysiologically in 12 adult albino rats with one eye removed at birth. For comparison, the contralateral projection was rather variable in the representation of the nasotemporal axis of the retina along the rostroc...

journal_title：Brain research

authors： Fukuda Y,Hsiao CF,Sawai H,Wakakuwa K

更新日期：1984-11-12 00:00:00

abstract：:Recent reports of the transsynaptic transfer of wheat germ agglutinin (WGA) in several systems are consistent with the hypothesis that WGA binds to endogenous glycoproteins(s) which undergo transsynaptic transfer. Such molecules might be involved in trophic interactions between neurons. Since these hypothetical glycop...

journal_title：Brain research

authors： Rhodes CH,Gonatas NK

更新日期：1986-12-03 00:00:00

abstract：:Painful experience is a complex entity made up of sensory, affective, motivational and cognitive dimensions. The neural mechanisms involved in pain perception acts in a serial and a parallel way, discriminating and locating the original stimulus and also integrating the affective feeling, involved in a special situati...

journal_title：Brain research

authors： Almeida TF,Roizenblatt S,Tufik S

更新日期：2004-03-12 00:00:00

abstract：:Ethanol withdrawal (ETX) after induction of ethanol dependence results in a syndrome that includes enhanced seizure susceptibility. During ETX in rodents, generalized audiogenic seizures (AGS) can be triggered by intense acoustic stimulation. Previous studies have implicated specific brainstem nuclei in the neuronal n...

journal_title：Brain research

authors： Feng HJ,Yang L,Faingold CL

更新日期：2007-04-13 00:00:00

abstract：:The developmental control of neuroblast proliferation is absolutely required for the assembly and function of the central nervous system. A lethal mutation in trol results in the failure of quiescent neuroblasts to begin division at the appropriate time. I have established a culture system in which quiescent neuroblas...

journal_title：Brain research

authors： Datta S

更新日期：1999-02-06 00:00:00

abstract：:Stroke is the major cause of acquired epilepsy in the adult population. The mechanisms of ischemia-induced epileptogenesis are not completely understood, but glutamate is associated with both ischemia-induced injury and epileptogenesis. The objective of this study was to develop an in vitro model of epileptogenesis in...

journal_title：Brain research

authors： Ziobro JM,Deshpande LS,Delorenzo RJ

更新日期：2011-01-31 00:00:00

abstract：:Postsynaptic effects of dimethylsulfoxide (DMSO) were studied at the frog cutaneous pectoris neuromuscular junction using electrophysiological techniques and computer assisted analysis. It was found that the average amplitude of extracellularly recorded miniature end-plate potentials (meppse) as well as the time const...

journal_title：Brain research

authors： Cherki-Vakil R,Meiri H

更新日期：1991-12-06 00:00:00

abstract：:This study examines projection to the cerebellar flocculus of eye movement-related neurons in the median and paramedian part of the cat pontine tegmentum between the trochlear and the abducens nucleus. They were identified by rhythmic activity related to horizontal vestibular nystagmus induced by sinusoidal rotation. ...

journal_title：Brain research

authors： Nakao S,Curthoys IS,Markham CH

更新日期：1980-02-10 00:00:00

abstract：:Repeated odorant or electrical stimulation of the frog olfactory nerve leads to long-lasting reduction of excitability of the receptor neurons. In the turtle olfactory nerve electrical stimulation causes an increase in extracellular potassium concentration due to the efflux of potassium from active axons. Elevated pot...

journal_title：Brain research

authors： Daston MM,Adamek GD,Gesteland RC

更新日期：1990-12-24 00:00:00

abstract：:Seizurogenic activity develops in many patients following brain injury and may be involved in the pathophysiological effects of brain trauma and stroke. We have evaluated the effects of the use-dependent sodium channel blocker RS100642, an analog of mexiletine, as a neuroprotectant and anti-seizure agent in a rat mode...

journal_title：Brain research

authors： Williams AJ,Tortella FC

更新日期：2002-04-05 00:00:00

abstract：:The localization of the glycine cleavage system was examined in the rat brain by immunohistochemistry using an antibody to P-protein (a constituent of the system). In all sites studied, the enzyme was confined to the astrocytes. The intensity of astrocyte staining varied in different brain regions, with the strongest ...

journal_title：Brain research

authors： Sato K,Yoshida S,Fujiwara K,Tada K,Tohyama M

更新日期：1991-12-13 00:00:00

abstract：:Electrical stimulation of the sural nerve (SN) revealed input from sural nerve afferents to L6 and L7 dorsal horn neurons that were not apparent using natural mechanical stimuli, especially in cells with variable latency responses to SN stimulation. Nearly all (31/32) cells that had reliable, fixed latency responses t...

journal_title：Brain research

authors： Pubols LM,Foglesong ME,Vahle-Hinz C

更新日期：1986-04-16 00:00:00

abstract：:The contribution of the activity of afferent fiber filaments to pain and hyperalgesia after administration of a plantar injection of interleukin-1 beta (IL-1 beta) to the hind-paw skin was investigated by recording action potentials of the rat dorsal root in response to mechanical and thermal stimuli. Touch stimuli we...

journal_title：Brain research

authors： Fukuoka H,Kawatani M,Hisamitsu T,Takeshige C

更新日期：1994-09-19 00:00:00

abstract：:Near-infrared spectroscopy (NIRS) enables noninvasive measurement of concentration changes of oxy- and deoxy-hemoglobin. The present study investigated cerebral representations of motion illusion by NIRS and examined several experimental procedures to determine an efficient procedure that can shorten the experimental ...

journal_title：Brain research

authors： Hashimoto T,Minagawa-Kawai Y,Kojima S

更新日期：2006-03-10 00:00:00

abstract：:Nineteen convergent neurones, 19 'non-noxious only' neurones and 13 'proprioceptive' neurones all with peripheral excitatory receptive fields on the ipsilateral hindpaw, were recorded in the lumbar dorsal horn of non-spinalized, anaesthetized rats. These neurones were all excited by the electrophoretic application of ...

journal_title：Brain research

authors： Villanueva L,Cadden SW,Le Bars D

更新日期：1984-04-23 00:00:00

abstract：:The distribution of agmatine (decarboxylated arginine) was mapped in the central nervous system (CNS) in the rat. Agmatine-like immunoreactivity was identified by light microscopy, exclusively in the cytoplasm of neuronal perikarya. Immunoreactive neurons were present in the cerebral cortex, predominantly within lamin...

journal_title：Brain research

authors： Otake K,Ruggiero DA,Regunathan S,Wang H,Milner TA,Reis DJ

更新日期：1998-03-16 00:00:00

abstract：:The present study determined whether cortical cholinergic neurons recover functionally following the loss of afferent projections from the nucleus basalis magnocellularis (nbm). At various time points following ibotenic acid lesions of the nbm, choline acetyltransferase (ChAT) activity or the capacity of cortical chol...

journal_title：Brain research

authors： Lapchak PA,Araujo DM,Pasinetti G,Hefti F

更新日期：1993-06-11 00:00:00

abstract：:There exists evidence to support the notion that the segmental reflex system is not fixed and inflexible, but rather is highly modifiable under a variety of circumstances. In this study the H-wave and M-wave recruitment curves were obtained from 19 subjects, utilizing the procedures outlined by Hugon. Each subject was...

journal_title：Brain research

authors： Koceja DM,Trimble MH,Earles DR

更新日期：1993-11-26 00:00:00

abstract：:Focal cerebral ischemia elicits an inflammatory response characterized by the infiltration and accumulation of leukocytes, as well as the secretion of inflammatory mediators (Clark et al., Brain Res. Bull., 35 (1994) 387-392; Garcia et al., Am. J. Pathol., 144 (1994) 188-199; Wang et al., J. Neurochem. 71 (1998) 1194-...

journal_title：Brain research

authors： Che X,Ye W,Panga L,Wu DC,Yang GY

更新日期：2001-06-01 00:00:00

abstract：:Intracellular recordings from CA3b/c neurons in rat hippocampal slices showed that reduction of the extracellular Cl- concentration from 136 to 53 mM produced a positive (+10 mV) shift in the reversal potential of GABAergic inhibitory postsynaptic potentials (IPSPs). This shift was not significantly different from the...

journal_title：Brain research

authors： Chamberlin NL,Dingledine R

更新日期：1988-03-29 00:00:00

abstract：:Single cell suspensions of early postnatal mouse cerebellum adhere to substrate-bound culture supernatants of the teratocarcinoma cell line PF-HR9 and can be inhibited to adhere by antibodies to the neural cell adhesion molecules L1 and N-CAM. Adhesion can also be inhibited by the glycosaminoglycans heparin and hepara...

journal_title：Brain research

authors： Werz W,Schachner M

更新日期：1988-10-01 00:00:00

abstract：:Molecular mechanism underlying ischemic stroke remains poorly understood. We previously reported glucose 6-phosphate dehydrogenase (G6PD) activity in pentose phosphate pathway (PPP) is activated via heat shock protein 27 (HSP27) phosphorylation at serine 85 (S85) by ataxia telangiectasia mutated (ATM) kinase during ce...

journal_title：Brain research

authors： Yamamoto Y,Hosoda K,Imahori T,Tanaka J,Matsuo K,Nakai T,Irino Y,Shinohara M,Sato N,Sasayama T,Tanaka K,Nagashima H,Kohta M,Kohmura E

更新日期：2018-05-15 00:00:00

abstract：:Protein phosphatases (PPs) regulate many substrates implicated in learning and memory. Conditioned taste aversion (CTA) learning, in which animals associate a novel taste paired with a toxin and subsequently avoid the taste, is dependent on several serine/threonine phosphatase substrates and the PP1-binding protein sp...

journal_title：Brain research

authors： Oberbeck DL,McCormack S,Houpt TA

更新日期：2010-08-12 00:00:00