Effect of serotonergic agents on regional concentrations of somatostatin- and neuropeptide Y-like immunoreactivities in rat brain.

abstract：:Infusion of 1 microgram of carbachol, a potent cholinergic agonist, into the lateral septum of the urethane-anaesthetized rat systematically caused the induction of clear-cut hippocampal theta (theta). However, infusion of an equivalent amount of the drug into the hippocampus, close to the recording electrode, failed ...

journal_title：Brain research

authors： Monmaur P,Ayadi K,Breton P

更新日期：1993-12-24 00:00:00

abstract：:Fast B neurons in bullfrog sympathetic ganglia were voltage clamped with two microelectrodes. Acetylcholine (ACh) was applied onto the soma membrane by iontophoresis. A rapid nicotinic inward current was followed by a slow muscarinic inward current. After an addition of scopolamine to Ringer solution so as to block th...

journal_title：Brain research

authors： Tokimasa T,North RA

更新日期：1984-03-19 00:00:00

abstract：:Effects of systemic administration of a single dose (50 mg/kg) of ethosuximide (ESM) on extracellularly recorded thalamic (nucleus centralis lateralis, CL; nucleus reticularis, RE) and cortical neurons and on cortical EEG activity of acute cats, have been studied. In intact animals ESM led to: (a) desynchronization of...

journal_title：Brain research

authors： Pellegrini A,Dossi RC,Dal Pos F,Ermani M,Zanotto L,Testa G

更新日期：1989-09-18 00:00:00

abstract：:Ethanol administration in long-sleep (LS) and short-sleep (SS) mice results in a large number of Fos-IR neurons in the supraoptic nucleus (SON) in LS, and almost no Fos-IR neurons in the same nucleus in SS mice. In contrast, isotonic saline, hypertonic saline, with or without ethanol, resulted in a similar pattern of ...

journal_title：Brain research

authors： Eisenman LM,Donovan HS,Johnson TE

更新日期：2002-05-10 00:00:00

abstract：:Rats selectively bred for high or low levels of emotionality represent an important and powerful tool to investigate the role of genetic variables in the occurrence of different anxiety disorders. In the present study, albino rats were selectively bred for differences in defensive freezing behavior in response to cont...

journal_title：Brain research

authors： de Castro Gomes V,Landeira-Fernandez J

更新日期：2008-10-03 00:00:00

abstract：:Previous reports of the distribution of calbindin, a 28 kDa vitamin D-induced calcium-binding protein, in the mammalian peripheral vestibular system postulated that this protein was involved in the calcium-dependent mechanisms occurring in the hair cells and ganglion cells. In this study, we examined the possibility o...

journal_title：Brain research

authors： Dechesne CJ,Thomasset M

更新日期：1988-05-16 00:00:00

abstract：:The ontogeny of muscarinic cholinergic receptors was studied in primary cultures of dissociated rat hippocampal cells. The specific [3H]quinuclidinyl benzilate [( 3H]QNB) to intact cells was detected after two days in culture. Scatchard analysis revealed only a unique binding site at all of the days tested, with a ver...

journal_title：Brain research

authors： Fernandez-Tomé P,Segal M

更新日期：1987-09-01 00:00:00

abstract：:Antibodies binding to the 150 kDa neurofilament protein NF150 have been purified from a serum raised by immunizing a rabbit with alpha-MSH. The NF150-binding antibodies were purified by affinity chromatography on a column of cytoskeletal proteins coupled to CNBr-activated Sepharose-4B. Immunocytochemical application o...

journal_title：Brain research

authors： Verhaagen J,Edwards PM,Jennekens FG,Schotman P,Gispen WH

更新日期：1987-02-24 00:00:00

abstract：:One hundred and four visual units of the (ventral) lateral geniculate nucleus (GL) of chicks (Gallus domesticus) were studied with extracellular microelectrodes. Most were extremely responsive to moving targets even at low speeds (0.1 degrees/sec). They were classified as follows. (1) movement-sensitive units with uni...

journal_title：Brain research

authors： Pateromichelakis S

更新日期：1979-05-11 00:00:00

abstract：:Pituitary adenylate-cyclase activating polypeptide (PACAP) is a neuropeptide originally isolated from the hypothalamus and located in many neuronal systems in both the central and peripheral nervous system. PACAP is also found in nerve fibers innervating the pineal gland, where it stimulates the secretion of the pinea...

journal_title：Brain research

authors： Møller M,Baeres FM

更新日期：2003-09-12 00:00:00

abstract：:Distribution of adult T cell leukemia derived factor (ADF/TRX), a human thioredoxin homologue, was studied by immunohistochemistry in gerbil brain during reperfusion after transient cerebral ischemia. In control brains, immunoreactivity was observed widely in the central nervous system, including the ependyma, tanycyt...

journal_title：Brain research

authors： Tomimoto H,Akiguchi I,Wakita H,Kimura J,Hori K,Yodoi J

更新日期：1993-10-15 00:00:00

abstract：:The cellular and intracellular localization of the epsilon-subspecies of protein kinase C (PKC) in the rat brain was demonstrated by immunocytochemistry using specific antibodies against epsilon-PKC. The epsilon-PKC-specific immunoreactivity was most abundant in the hippocampal formation, olfactory tubercle and Callej...

journal_title：Brain research

authors： Saito N,Itouji A,Totani Y,Osawa I,Koide H,Fujisawa N,Ogita K,Tanaka C

更新日期：1993-04-02 00:00:00

abstract：:Corticotropin-releasing factor (CRF) in the brain plays an important role in regulations of physiological and behavioral processes, yet CRF distribution in tree shrew brain has not been thoroughly and systematically reported. Here we examined the distribution of CRF immunoreactivity in the brain of tree shrews (Tupaia...

journal_title：Brain research

authors： Shu YM,Ni RJ,Sun YJ,Fang H,Zhou JN

更新日期：2015-08-27 00:00:00

abstract：:We investigated the effects of inverting facial contour (hair and chin) and features (eyes, nose and mouth) on processing for static and dynamic face perception using magnetoencephalography (MEG). We used apparent motion, in which the first stimulus (S1) was replaced by a second stimulus (S2) with no interstimulus int...

journal_title：Brain research

authors： Miki K,Takeshima Y,Watanabe S,Honda Y,Kakigi R

更新日期：2011-04-06 00:00:00

abstract：:The local cerebral circulatory and metabolic effects of MK-801, a selective non-competitive N-methyl-D-aspartate receptor antagonist have been examined in conscious rats with quantitative autoradiographic techniques using [14C]iodoantipyrine and [14C]2-deoxyglucose as tracers. Local cerebral blood flow (CBF) and local...

journal_title：Brain research

authors： Nehls DG,Park CK,MacCormack AG,McCulloch J

更新日期：1990-03-19 00:00:00

abstract：:Estrogens exert a wide variety of actions on reproductive and non-reproductive functions. These effects are mediated by slow and long lasting genomic as well as rapid and transient non-genomic mechanisms. Besides the host of studies demonstrating the role of genomic actions at the physiological and behavioral level, m...

journal_title：Brain research

authors： Cornil CA,Ball GF,Balthazart J

更新日期：2006-12-18 00:00:00

abstract：:In alert cats, extracellular spikes of neurons in the medial pontine tegmentum were recorded simultaneously with whole nerve discharges of the abducens and medial rectus nerves during horizontal vestibular nystagmus. Nystagmus-related neurons were classified by their firing patterns in relation to the abrupt cessation...

journal_title：Brain research

authors： Curthoys IS,Nakao S,Markham CH

更新日期：1981-10-05 00:00:00

abstract：:The nitric oxide (NO) metabolome and the NO metabolite-based neurovascular protective pathways are dysregulated after stroke. The major NO metabolite S-nitrosoglutahione (GSNO) is essential for S-nitrosylation-based signaling events and the inhibition of S-nitrosoglutahione (GSNO)-metabolizing enzyme GSNO reductase (G...

journal_title：Brain research

authors： Khan M,Kumar P,Qiao F,Islam SMT,Singh AK,Won JS,Feng W,Singh I

更新日期：2020-08-15 00:00:00

abstract：:In our previous study, we have found that leucine-rich repeats and immunoglobulin-like domains 1(LRIG1) can improve the chemosensitivity in U251 cells whereas the role of LRIG1 in multidrug resistance (MDR) remains unknown. Here, we reported that LRIG1 can reverse MDR by inhibiting epidermal growth factor (EGF) recept...

journal_title：Brain research

authors： Liu B,Guo Z,Dong H,Daofeng T,Cai Q,Ji B,Zhang S,Wu L,Wang J,Wang L,Zhu X,Liu Y,Chen Q

更新日期：2015-06-22 00:00:00

abstract：:Distribution of the monocarboxylate transporter MCT1 has been investigated in the cortex of normal adult human brain. Similarly to the glucose transporter GLUT1 55 kDa isoform, MCT1 was found to be strongly expressed on blood vessels in all cortical layers. In addition, laminar analysis revealed intense MCT1 expressio...

journal_title：Brain research

authors： Chiry O,Pellerin L,Monnet-Tschudi F,Fishbein WN,Merezhinskaya N,Magistretti PJ,Clarke S

更新日期：2006-01-27 00:00:00

abstract：:The effects of glucagon injections (25, 100 and 200 ng) into the paraventricular nucleus of the hypothalamus (PVN) were investigated in an open-circuit calorimeter. Wistar rats were tested, with no food available during the tests. High doses of glucagon (100 and 200 ng) produced small and short-lasting increases in en...

journal_title：Brain research

authors： Atrens DM,Menéndez JA

更新日期：1993-12-10 00:00:00

abstract：:The functional role of many central nervous structures has been inferred from the temporal relationship of a neuronal response with the different sensory and motor events in an experimental design such as when an animal performs a trained movement in response to a conditioned stimulus. However, this kind of data analy...

journal_title：Brain research

authors： Seal J,Commenges D,Salamon R,Bioulac B

更新日期：1983-11-14 00:00:00

abstract：:Serotonin (5HT) systems play important roles in brain development, and early perturbations of 5HT receptor expression produce permanent changes in 5HT synaptic function and associated behaviors. We exposed pregnant Rhesus monkeys to environmental tobacco smoke (ETS) during gestation and for up to 3 months postnatally ...

journal_title：Brain research

authors： Slotkin TA,Pinkerton KE,Tate CA,Seidler FJ

更新日期：2006-09-21 00:00:00

abstract：:Prepro-vasoactive intestinal peptide (prepro-VIP) is processed to at least three biologically active peptides: VIP, peptide histidine isoleucine (PHI) and an extended PHI, peptide histidine valine (PHV). The aim of the present investigation was by chromatography combined with RIA and immunocytochemistry to determine w...

journal_title：Brain research

authors： Mikkelsen JD,Fahrenkrug J

更新日期：1994-09-05 00:00:00

abstract：:In vivo microdialysis techniques were used to examine the effects of estrogen on potassium-stimulated acetylcholine release in the hippocampus and overlying cortex of adult, ovariectomized rats. Estrogen treatment resulted in a significant increase in the percent change in acetylcholine release induced by potassium re...

journal_title：Brain research

authors： Gibbs RB,Hashash A,Johnson DA

更新日期：1997-02-21 00:00:00

abstract：:Xenopus laevis tadpoles functionally recover from spinal cord transection. Because this recovery requires the tadpole to metamorphose, it may result from compensatory changes initiated by de novo growth of axons involved in limb dominant locomotion rather than from regeneration of cut axons. To determine whether axona...

journal_title：Brain research

authors： Gibbs KM,Szaro BG

更新日期：2006-05-09 00:00:00

abstract：:Opioid peptides and their receptors have been localized to the inner ear of the rat and guinea pig mammalian models. The expression of mu opioid receptor (MOR) in the human and mouse cochlea is not yet known. We present MOR protein localization by immunohistochemistry and mRNA expression by in situ hybridization in th...

journal_title：Brain research

authors： Nguyen KD,Mowlds D,Lopez IA,Hosokawa S,Ishiyama A,Ishiyama G

更新日期：2014-11-24 00:00:00

abstract：:Axon-to-myelin transfer of lipids precursors have been studied in the rabbit optic system by intraocular injection of [32P]orthophosphate, [14C]glycerol and [3H]glycerol. Choline and ethanolamine phosphoglycerides and myelin showed increasing [32P]-radioactivity between 7 and 21 days following injection, while [3H]- a...

journal_title：Brain research

authors： Ledeen RW,Haley JE

更新日期：1983-06-20 00:00:00

abstract：:The presence of calretinin and calbindin immunoreactivity is studied in the retina of larval and adult lamprey and their respective distributions are compared. Calretinin distribution is also studied in the retina of transforming stages. Western blot analysis in brain extracts showed a 29-kDa band with both polyclonal...

journal_title：Brain research

authors： Villar-Cheda B,Abalo XM,Anadón R,Rodicio MC

更新日期：2006-01-12 00:00:00

abstract：:The ultrastructural morphology and synaptic associations between enkephalin-containing neurons and sensory afferents was examined in the caudalis portion of rat spinal trigeminal complex, the region corresponding to Rexed's layer II of the dorsal horn. Specific antiserum to Met5-enkephalin was localized by the peroxid...

journal_title：Brain research

authors： Sumal KK,Pickel VM,Miller RJ,Reis DJ

更新日期：1982-09-30 00:00:00