Abstract:
:In vivo microdialysis techniques were used to examine the effects of estrogen on potassium-stimulated acetylcholine release in the hippocampus and overlying cortex of adult, ovariectomized rats. Estrogen treatment resulted in a significant increase in the percent change in acetylcholine release induced by potassium relative to controls, particularly after prolonged (90 min) exposure to high potassium. The data suggest that estrogen may help to maintain cholinergic function under conditions where cholinergic afferents to the hippocampal formation and cortex are challenged or impaired.
journal_name
Brain Resjournal_title
Brain researchauthors
Gibbs RB,Hashash A,Johnson DAdoi
10.1016/s0006-8993(96)01375-3subject
Has Abstractpub_date
1997-02-21 00:00:00pages
143-6issue
1eissn
0006-8993issn
1872-6240pii
S0006899396013753journal_volume
749pub_type
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