Abstract：
:The optic nerve of anesthetized cats was completely cut and the autologous sciatic nerve was transplanted. Sixty days later some populations of retinal ganglion cells were shown to regenerate the axon with retrograde HRP labeling. We verified that ganglion cells that had projected to the lateral geniculate nucleus (LGN) were able to regenerate through the transplant with a double-labeling method: diI was injected into the LGN prior to the transplantation, and dextran-fluorescein was injected into the graft after axonal regeneration. Intracellular injection of HRP into regenerating ganglion cells in an in vitro preparation revealed that the two major cell types projecting to the LGN, alpha and beta, regenerated axons and showed normal dendritic morphology.
journal_name
Brain Resjournal_title
Brain researchauthors
Watanabe M,Sawai H,Fukuda Ydoi
10.1016/0006-8993(91)91253-wsubject
Has Abstractpub_date
1991-09-27 00:00:00pages
330-3issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(91)91253-Wjournal_volume
560pub_type
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