Abstract：
:Extracellular amino acids were followed in the hippocampus during sustained seizures induced by systemic administration of kainic acid (KA) or bicuculline (BC). KA epilepsy was associated with marked increases in phosphoethanolamine (PEA) and taurine. Alanine and ethanolamine were moderately raised while other amino acids were unaffected. BC seizures encompassed a slightly different pattern of alterations. In contrast to KA seizures, BC epilepsy had no effect on taurine. Significant increments were observed for PEA and alanine while elevations of ethanolamine were subtle. In both types of seizures, glutamate and GABA remained unaffected extracellularly, probably due to efficient recapture mechanisms.
journal_name
Brain Resjournal_title
Brain researchauthors
Lehmann A,Hagberg H,Jacobson I,Hamberger Adoi
10.1016/0006-8993(85)91422-2subject
Has Abstractpub_date
1985-12-16 00:00:00pages
147-51issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(85)91422-2journal_volume
359pub_type
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