Abstract:
:A morphosyntactic agreement violation during reading elicits a well-documented biphasic ERP pattern (LAN+P600). The cognitive variables that affect both the amplitude of the two components and the topography of the anterior negativity are still debated. We studied the ERP correlates of the violation of a specific agreement feature based on the phonology of the critical word. This was compared with the violation of a lexical feature, namely grammatical gender. These two features are different both in the level of representation involved in the agreement computation and in terms of their role in establishing structural relations with possible following constituents. The ERP pattern elicited by the two agreement violations showed interesting dissociations. The LAN was distributed ventrally for both types of violation, but showed a central extension for the gender violation. The P600 showed an amplitude modulation: this component was larger for phonotactic violations in its late time window (700-900 ms). The former result is indicative of a difference in the brain structures recruited for the processing of violations at different levels of representation. The P600 effect is interpreted assuming a hierarchical relation among features that forces a deeper reanalysis of the violation involving a word form property. Finally the two features elicit distinct end-of-sentence wrap-up effects, consistent with the different roles they play in the processing of the whole sentence.
journal_name
Brain Resjournal_title
Brain researchauthors
Molinaro N,Vespignani F,Job Rdoi
10.1016/j.brainres.2008.06.064subject
Has Abstractpub_date
2008-09-04 00:00:00pages
161-76eissn
0006-8993issn
1872-6240pii
S0006-8993(08)01530-8journal_volume
1228pub_type
临床试验,杂志文章相关文献
BRAIN RESEARCH文献大全abstract::The opposing actions of diphenylhydantoin (DPH) and calcium on the level of [32P]phosphate incorporation into particular rat and human brain proteins have been demonstrated in this study by employing the techniques of acrylamide gel electrophoresis and autoradiography. In the presence of calcium several brain proteins...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(77)90930-1
更新日期:1977-09-23 00:00:00
abstract::The contribution of motor and intralaminar thalamic nuclei to the changes of [3H]GABA release evoked in both caudate nuclei (CN) and both substantia nigra (SN) by a unilateral nigral application of muscimol (10(-6) M) was investigated on halothane-anaesthetized cats. Acute lesions were performed on one side of the tha...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)91206-x
更新日期:1984-06-15 00:00:00
abstract::Ligation of CD27, a member of the tumor necrosis factor (TNF) receptor family, by its ligand CD70 is thought to be important in T cell activation, expansion and survival, B cell activation, and NK cell activation. We examined the role of CD70 in Theiler's murine encephalomyelitis virus-induced demyelinating disease (T...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2009.12.058
更新日期:2010-03-04 00:00:00
abstract::The purpose of this study was to determine the ultrastructure of the blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) in G93A SOD1 mice modeling ALS at different stages of disease. Electron microscope examination of brainstem, cervical and lumbar spinal cords was performed in ALS mice at early and late s...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.04.044
更新日期:2007-07-09 00:00:00
abstract::The genetic architecture of amyotrophic lateral sclerosis (ALS) is being increasingly understood. In this far-reaching review, we examine what is currently known about ALS genetics and how these genes were initially identified. We also discuss the various types of mutations that might underlie this fatal neurodegenera...
journal_title:Brain research
pub_type: 杂志文章,评审
doi:10.1016/j.brainres.2014.10.009
更新日期:2015-05-14 00:00:00
abstract::Antibody has been prepared to purified neurofilament protein extracted from calf brain. This antibody crossreacts with brain and nerve extracts from all mammals tested but fails to crossreact with frog, cod and chicken nerve extracts. Thus the serologic homology of these neurofilament proteins appears to be restricted...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(77)91074-5
更新日期:1977-10-07 00:00:00
abstract::We developed a rat spinal cord injury model and investigated whether endogenous endothelin (ET)-1 plays a role in astrocytic growth after injury. Immunohistochemical study showed that the number of immature astrocytes (ACs) exhibiting strong reactivity to the monoclonal antibody, RC1, markedly increased 24 h after the...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00524-0
更新日期:1996-07-29 00:00:00
abstract::Cerebral cortical blood flow (CBF) was measured autoradiographically in conscious mice without the monoamine oxidase B (MAOB) gene (KO, n=11) and the corresponding wild-type animals (WILD, n=11). Subgroups of animals of each genotype received a continuous intravenous infusion over 30 min of phenylethylamine (PEA), an ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)01167-1
更新日期:1999-04-03 00:00:00
abstract::Bilateral microinjections of the neuroleptic, cis-flupenthixol, were made into 56 forebrain targets distributed across various dopamine (DA) terminal fields in the forebrain. Drug effects on medial forebrain bundle (MFB) stimulation-produced reward were assessed with a rate-frequency procedure implemented in a runway ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)91400-5
更新日期:1989-01-16 00:00:00
abstract::Six cats were trained to eat while partially restrained and while thermal pulse stimuli (43-60 degrees C, 5 s duration) were delivered to the upper hindlimbs. Food and stimulus delivery were under programmed electronic control. The probability and latency of 3 natural, unlearned nocifensive behaviors were electronical...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)91036-6
更新日期:1989-10-30 00:00:00
abstract::The effects of dopamine D1 and D2 selective drugs on the responses evoked in accumbens neurons by stimulation of cortical afferents were studied in an in vitro brain slice preparation. The D2-specific antagonist sulpiride (1-10 microM) increased, whereas the D2 agonist quinpirole (1-20 microM) occasionally attenuated ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)90263-1
更新日期:1994-01-14 00:00:00
abstract::Recordings of single unit activity before, during and after a 1-h continuous exposure were made from the mitral cell layer of the olfactory bulbs of awake rabbits. Thirteen complete 1-h exposures were performed using 8 neurons, while a further 6 neurons were lost before the end of the exposure. During the first few mi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90951-9
更新日期:1982-10-28 00:00:00
abstract::The objective was to further test the hypothesis that aluminum (Al) citrate transport across the blood-brain barrier is mediated by a monocarboxylate transporter (MCT). Speciation calculations showed that Al citrates were the predominant Al species under the conditions employed. Al citrate did not inhibit lactate upta...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(02)02234-5
更新日期:2002-03-15 00:00:00
abstract::Growth of cultured N1E-115 neuroblastoma cells in 1 microM A23187 for 2 days to elevate internal Ca reduced both membrane Na current and the transient, but not steady state, component of outward K current. Na channel mRNA abundance was reduced by an average value of 45% without effect on Kv3.1. Increases in internal C...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)01340-7
更新日期:1996-01-15 00:00:00
abstract::Choline supplementation of the maternal diet has long-term facilitative effects on spatial and temporal memory processes in the offspring. To further delineate the impact of early nutritional status on brain and behavior, we examined effects of prenatal-choline availability on hippocampal oscillatory frequency bands i...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2008.08.077
更新日期:2008-10-27 00:00:00
abstract::The effect of hippocampal kindling on neuronal and glial marker proteins was studied in the rat by immunochemical methods. In hippocampus, pyriform cortex and amygdala there was an increase in glial fibrillary acidic protein (GFAP), indicating reactive gliosis, and an increase in the glycolytic enzyme NSE, suggesting ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90791-9
更新日期:1990-10-29 00:00:00
abstract::α-Synuclein (α-syn) and oxidative stress play pivotal roles in the pathogenesis of Parkinson's disease (PD). However, the mechanisms underlying the interaction between α-syn and oxidative stress remain poorly understood. The present study provides evidence to suggest that the nuclear translocation of α-syn increases d...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2013.01.024
更新日期:2013-03-15 00:00:00
abstract::In this study, noradrenergic (NE) terminals in the dorsal raphe were identified by [3H]NE electron microscopic (EM) autoradiography. Lesioning of NE terminals by treatment with the selective catecholamine neurotoxin, 6-hydroxydopamine produced a marked decrease in NE-labelled terminals. [3H]5-HT EM autoradiography of ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(81)90646-6
更新日期:1981-01-05 00:00:00
abstract::Slices of the molecular layer of the dentate gyrus of the hippocampal formation were incubated with either [14C]glucose, [14C]pyruvate or 14C glutamine and the efflux of endogenous and radioactive glutamate was monitored under various conditions. After prelabeling with either [14C]glutamine or [14C]glucose elevation o...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)90306-8
更新日期:1979-06-08 00:00:00
abstract::This study has assessed the neuroprotective efficacy of five AP-1 inhibitory peptides in an in vitro excitotoxicity model. The five AP-1 inhibitory peptides and controls of the JNK inhibitor peptide (JNKI-1D-TAT) and TAT cell-penetrating-peptide were administered to primary cortical neuronal cultures prior to kainic a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2010.09.007
更新日期:2010-11-11 00:00:00
abstract::The effects of repetitive pilocarpine-induced status epilepticus (SE) in the hippocampal Na(+)/K(+)ATPase activity were studied in developing rat. Na(+)/K(+)ATPase is a membrane-bound enzyme responsible for the active transport of sodium and potassium ions through the membrane. It is necessary to maintain neuronal exc...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.12.068
更新日期:2007-03-23 00:00:00
abstract::Cerebellar Purkinje neurons possess AMPA ((RS)-alpha-amino-3-hydroxyl-5- methyl-4-isoxazolepropionic acid)-sensitive ionotropic glutamate receptors (AMPA GluRs) and ACPD ((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid)-sensitive metabotropic glutamate receptors (mGluRs). The contributions of these receptors to resp...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)91186-v
更新日期:1993-12-17 00:00:00
abstract::Many of our everyday actions are only appropriate in certain situations and selecting the appropriate behavior requires that we use current context and previous experience to guide our decisions. The current study examined hippocampal functional connectivity with prefrontal and striatal regions during a task that requ...
journal_title:Brain research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.brainres.2011.09.038
更新日期:2011-11-14 00:00:00
abstract::The biosynthetic activity of extra-hypothalamic vasopressin (VP) neurons in the bed nucleus of the stria terminalis (BNST) is regulated by gonadal steroids. These neurons have also been implicated in a number of behaviors that are impaired in aging. We previously reported that VP mRNA labelling in the BNST is decrease...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(10)80030-7
更新日期:1992-06-26 00:00:00
abstract::Cyclooxygenase-2 (COX-2) is the predominant isoform of cyclooxygenase in brain. COX-2 activity produces oxidative stress and results in the production of prostaglandins that have many injurious effects. COX-2 transcription is induced by synaptic activity; therefore, COX-2 activity could contribute to epileptic neurona...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2005.05.038
更新日期:2005-07-19 00:00:00
abstract::Attention-Deficit/Hyperactivity Disorder (ADHD) is associated with deficits in fluid reasoning, which may be related to self-regulation of cognition and behavior, and requires intact attention, working memory, and inhibition skills. No functional magnetic resonance imaging (fMRI) studies have directly examined fluid r...
journal_title:Brain research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.brainres.2012.05.021
更新日期:2012-07-17 00:00:00
abstract::Theory of Mind (ToM) has been defined as our ability to predict behaviors of others in terms of their underlying intentions. While the developmental trajectory of ToM had been thought to be invariant across cultures, several ToM studies conducted outside the Anglo-American cultural or linguistic milieus have obtained ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.06.022
更新日期:2007-08-20 00:00:00
abstract::The non-cholinergic excitatory potential elicited in neurons of the isolated inferior mesenteric ganglia was depressed by bath application of Met- or Leu-enkephalin and enhanced by naloxone or naltrexone. The membrane depolarization induced by exogenously applied putative transmitter substance P was not appreciably af...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90211-6
更新日期:1982-03-04 00:00:00
abstract::Ibogaine, a naturally occurring iboga alkaloid, has been claimed to be effective in treating addiction to opioids and stimulants, and has been reported to inhibit morphine and cocaine self-administration in rats. However, ibogaine also has acute nonspecific side effects (e.g. tremors, decreased motivated behavior in g...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(96)00056-x
更新日期:1996-05-06 00:00:00
abstract::We studied the effects of axotomy or neurotoxin on the survival of substantia nigra pars compacta (SNpc) neurons in two strains of mice, FVB/N or C57BL/6. Fluoro gold (FG) was injected into both striata of the mice to retrogradely label the nigrostriatal neuronal population. Ten days later, these neurons were axotomiz...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2003.09.066
更新日期:2003-12-24 00:00:00