Abstract：
:ACTH4-10, a fragment of the adrenocorticotropic hormone (ACTH) molecule, has marked effects on the compensation process following unilateral labyrinthectomy. In Rana temporaria ACTH4-10-treatment (5-250 micrograms/kg) influences both the acquisition and the maintenance of the compensated state. The compensation process is slowed down by hypophysectomy but can then be restored by the administration of ACTH4-10. It is concluded that ACTH-like neuropeptides might physiologically be involved in the plastic processes underlying functional recovery from CNS lesions.
journal_name
Brain Resjournal_title
Brain researchauthors
Flohr H,Lüneburg Udoi
10.1016/0006-8993(82)91158-1subject
Has Abstractpub_date
1982-09-23 00:00:00pages
169-73issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(82)91158-1journal_volume
248pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:In over half a century numerous studies have demonstrated that different odorants produce individually different spatial patterns of neural receptor activity on the olfactory mucosa. However, the thought that these differential activity patterns could be the neural code underlying olfactory perception has not been tes...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(03)02512-5
更新日期：2003-08-15 00:00:00
abstract：:To investigate the reversibility of neuronal functions during deep and mild hypothermia, we have examined changes in membrane properties of pyramidal neurons of the CA3 region of hippocampal slices during cooling and rewarming (8 approximately 37 degrees C) of the perfusion medium. Hypothermia reduced the excitatory p...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)03285-6
更新日期：2001-03-02 00:00:00
abstract：:The effects of chronic administration of naloxone, morphine and met-enkephalin on benzodiazepine (BDZ) receptor binding in rat brain were determined 2 and 50 days after treatments were accomplished. Two days after naloxone treatment (75 micrograms/h s.c. for 14 days), enhanced BDZ receptor binding was observed in cing...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91668-i
更新日期：1993-05-28 00:00:00
abstract：:Bilateral lesions of the amygdaloid complex in C57BL/6 mice prevented the occurrence of morphine-induced hypermotility (running fit). This effect, that was different from that observed after hippocampal lesions but similar to that observed after caudate lesions, confirms the role of the basal ganglia catecholaminergic...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(89)91328-0
更新日期：1989-02-06 00:00:00
abstract：:Chemical synaptic transmission was studied with microelectrode techniques in isolated frog cerebella maintained in vitro. Purkinje cell (PC) EPSPs, elicited by selective monosynaptic electrical stimulation of both the parallel fiber (PF) and climbing fiber (CF) inputs, could be inverted by depolarizing (outward) curre...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(76)91005-2
更新日期：1976-09-10 00:00:00
abstract：:The present study examined the effects of excitotoxins which activate distinct excitatory amino acid (EAA) receptor subtypes on the levels of Methionine-enkephalin-like immunoreactivity (ME-i.r.) in the striatum and globus pallidus, with a view to developing a model of the striatopallidal enkephalin deficit that preva...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90029-b
更新日期：1990-12-17 00:00:00
abstract：:The effects of estrus and prolonged estradiol benzoate (EB) treatment on estrogen receptor-like immunoreactivity (ER-LI) were studied in the female Brazilian opossum (monodelphis domestica) brain. In general, both estrus animals and EB treated animals had reduced ER-LI in specific brain regions when compared to ovarie...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90632-w
更新日期：1993-07-16 00:00:00
abstract：:Malignant glioma cells maintain an elevated intracellular pH (pH(i)) within hypoxic-ischemic tumor microenvironments through persistent activation of sodium-proton transport (McLean et al., 2000). Amiloride has been reported to selectively kill human malignant glioma cell lines but not primary astrocytes (Hegde et al....
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.09.059
更新日期：2010-12-02 00:00:00
abstract：:Bombesin (BN)- and substance P (SP)-containing neurons are found in the dorsal root ganglia, and project to the dorsal horn of the spinal cord. The present study was undertaken to determine if chronic deafferentation of the cat spinal cord would affect BN or SP receptors in the spinal cord. Ten and 30 days after a uni...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90744-9
更新日期：1985-09-23 00:00:00
abstract：:Methylazoxymethanol acetate (MAM)-induced cortical hypoplasia resulted in a 2-fold increase in the concentration of norepinephrine and its metabolite, 3-methoxyl-4-hydroxyphenylglycol sulfate, and a 26% decrease in the Bmax for the beta-receptor ligand, [3H]dihydroalprenolol (DHA) in the rat cortex. Chronic treatment ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(82)90195-x
更新日期：1982-08-01 00:00:00
abstract：:(1) Changes during development in the levels of proteinases and peptidases were measured in brain homogenates. At all ages di- and tripeptidase levels were 7-15-fold higher than proteinase activity. (2) Cathepsin A and D and neutral proteinase activity first decreased (during the 5 days before birth) and then increase...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(75)90705-2
更新日期：1975-03-21 00:00:00
abstract：:Fifteen adult male Sprague-Dawley rats were implanted with a set of electrodes for standard sleep recordings. A stainless steel cannula was also implanted into the lateral ventricle of these rats. Fifteen additional rats were implanted with a cannula alone. Rats with electrodes were habituated for 3 days or more to th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90888-5
更新日期：1994-10-03 00:00:00
abstract：:Our purpose was to investigate the cortical information processing of autobiographical fact violation (AFV) in self-referential questions. We expected that AFV in a self-referential question would evoke a characteristic pattern of neural synchrony and event-related potentials (ERPs). Averaged ERP and event-related syn...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2017.02.013
更新日期：2017-05-01 00:00:00
abstract：:Antisera against rat-liver S-adenosylhomocysteine hydrolase (SAH-hydrolase) and calf intestinal mucosal adenosine deaminase (ADA) were raised in rabbits and subsequently used to determine the distribution of the corresponding enzymes in rat-brain using the peroxidase-antiperoxidase immunohistochemical procedure. SAH-h...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90480-4
更新日期：1986-04-09 00:00:00
abstract：:Full limbic seizures were kindled in rats by repeated, bi-daily microinjections of glutamate (1.5 mumol) into the basolateral amygdala. Co-administration of the N-methyl-D-aspartate (NMDA) receptor antagonist 2-amino-7-phosphonoheptanoic acid with the glutamate, prevented the development of both electroencephalographi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)91279-p
更新日期：1990-01-08 00:00:00
abstract：:We have recently reported that the burst firing neurons are found in layer III as well as in layer V of cat sensorimotor cortex in vitro. In the present study, we examined the synaptic excitability of layer III neurons by white matter stimulation and compared with their firing patterns against the current injections t...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01850-8
更新日期：1999-09-18 00:00:00
abstract：:Recent studies, which have shown an increase of plasma vasopressin (VP) in experimental motion sickness and the efficacy of VP antagonists for motion sickness, suggest an important role of VP in the development of vestibulo-autonomic responses. We have recently found evidence of the co-existence of vasopressinergic ne...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02799-8
更新日期：2001-09-28 00:00:00
abstract：:Distribution of adult T cell leukemia derived factor (ADF/TRX), a human thioredoxin homologue, was studied by immunohistochemistry in gerbil brain during reperfusion after transient cerebral ischemia. In control brains, immunoreactivity was observed widely in the central nervous system, including the ependyma, tanycyt...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90130-f
更新日期：1993-10-15 00:00:00
abstract：:Dynorphin and other kappa opioid agonists are thought to elicit aversive actions and changes in motor activity through direct or indirect modulation of dopamine neurons in ventral tegmental area (VTA) and substantia nigra (SN), respectively. We comparatively examined the immunoperoxidase localization of anti-dynorphin...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90693-h
更新日期：1993-02-05 00:00:00
abstract：:The onset of adult hypothyroidism causes neuronal damage in the CA3 hippocampal region, which is attenuated by T(4) administration. We analyzed the expression of molecular proliferation markers (Cyclin D1 and PCNA), cellular damage-arrest (p53 and p21), and apoptosis (Bax/Bcl-2 index) in the hippocampus of hypothyroid...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.02.043
更新日期：2009-05-19 00:00:00
abstract：:The rat medial prefrontal cortex is known to have diverse brain functions such as learning and memory, attention, and behavioral flexibility. Although these functions are affected by monoamines (dopamine (DA), noradrenaline (NA) and serotonin (5-HT)) and acetylcholine (ACh), the detailed mechanisms remain unclear. The...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.03.039
更新日期：2004-06-25 00:00:00
abstract：:Electrical stimulation in the dorsal acoustic stria (DAS) and the posterior and dorsal part of the ventral cochlear nucleus (VCN) was used to identify the response properties of efferent axons from the dorsal cochlear nucleus (DCN) in unanesthetized, decerebrate cats. Responses recorded in the DCN of this preparation ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)91091-4
更新日期：1980-10-27 00:00:00
abstract：:The effect of bilateral lesion of the accessory olfactory bulb (AOB) on the mating-induced enhancement of sexual receptivity was investigated in ovariectomized (OVX) female rats. Lesions of the AOB significantly reduced the lordosis-to-mount (L/M) ratio in mating tests conducted 20 to 50 days after the lesion but L/M ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90902-4
更新日期：1994-04-11 00:00:00
abstract：:Striatal glial cell line-derived neurotrophic factor (GDNF) mRNA levels in both young (2-month old) and old (11-month old) C57BL/6J mice were quantified at 3, 7 and 21 days following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment. MPTP did not alter the expression of GDNF mRNA in these animals. Immunore...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01254-8
更新日期：1999-05-01 00:00:00
abstract：:An acute pain animal model for fMRI study would provide useful spatial and temporal information for studying the supraspinal nociceptive neuronal responses. The aim of the present study was to investigate whether the nociceptive responses in different brain areas can be differentiated by using functional magnetic reso...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)02094-7
更新日期：2001-04-06 00:00:00
abstract：:The genetic architecture of amyotrophic lateral sclerosis (ALS) is being increasingly understood. In this far-reaching review, we examine what is currently known about ALS genetics and how these genes were initially identified. We also discuss the various types of mutations that might underlie this fatal neurodegenera...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2014.10.009
更新日期：2015-05-14 00:00:00
abstract：:The DNA content and activity of acid and alkaline deoxyribonucleases (DNases) were measured through age 60 days in the hypothalamus of female rats injected s.c. with 1.25 mg testosterone propionate 48 h after birth. DNA significantly increases through age 60 days, however, androgenization does not affect the DNases or...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(85)90273-1
更新日期：1985-02-01 00:00:00
abstract：:Binding activities specific for each of [3H]prostaglandin (PG) D2, E2 and F2 alpha were detected in the P2 fraction of the human brain homogenates. The bindings were time-dependent, saturable and of high affinity; Kd values were 30 nM for all the PG bindings. Regional distribution of these binding activities was deter...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91358-7
更新日期：1985-09-02 00:00:00
abstract：:The neurotrophic effect of bFGF on dopamine (DA) neurons in vitro depends upon its mitogenic activity on glial cells. We examined whether glial secretion of the dopaminergic growth factor GDNF is responsible for the trophic activity of bFGF on mesencephalic DA neurons. When added with lower concentrations of bFGF, GDN...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00311-3
更新日期：1996-06-10 00:00:00
abstract：:The relationship between carotid body chemoreceptor activity and flow was studied in preparations superfused in vitro. The carotid bodies were excised from pentobarbitone-anesthetized cats and superfused with modified Tyrode's solution, buffered with HEPES-NaOH to pH 7.41. The bath temperature was kept constant at 37....
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90110-2
更新日期：1988-07-05 00:00:00
