Acromelic acid is a much more potent excitant than kainic acid or domoic acid in the isolated rat spinal cord.

abstract：:In serum-free monolayer cultures of early postnatal weaver (wv/wv) cerebellum granule neurons show decreased attachment, survival and neurite outgrowth when compared to wild-type (+/+) littermate cultures. wv/wv Astrocytes display a more epithelioid morphology and altered proliferation. However, both morphology and pr...

journal_title：Brain research

authors： Fischer G,Keilhauer G,Schachner M

更新日期：1986-08-01 00:00:00

abstract：:Brainstem noradrenergic neurons located in the A5, A6, and A7 catecholamine cell groups provide the entire noradrenergic innervation of the spinal cord. We have previously demonstrated that noradrenergic neurons in the A6 and A7 cell groups innervate the ventral and dorsal horns, respectively. Since the specific spina...

journal_title：Brain research

authors： Clark FM,Proudfit HK

更新日期：1993-07-09 00:00:00

abstract：:Amnestic type mild cognitive impairment (aMCI) refers to a transitional stage between normal aging and Alzheimer's disease (AD). Whilst posterior cingulate cortex (PCC) is believed to have a key role in a default network and be involved in the pathophysiology of AD, few studies have investigated whole-brain functional...

journal_title：Brain research

authors： Bai F,Watson DR,Yu H,Shi Y,Yuan Y,Zhang Z

更新日期：2009-12-11 00:00:00

abstract：:We studied the effects of transcranial magnetic stimulation (TMS) on muscle activation patterns and joint kinematics during oscillatory movements of a joint within a two-joint (elbow-wrist) synergy. Healthy young adults (N=8) performed cyclic movements in one of the joints while the other joint was or was not involved...

journal_title：Brain research

authors： Latash ML,Danion F,Bonnard M

更新日期：2003-01-31 00:00:00

abstract：:Confocal microscopy and the Ca(2+)-sensitive fluorescent dye fluo-3 were used to study subcellular Ca2+ signals in embryonic, neonatal, and adult dorsal root ganglion (DRG) neurons in excised dorsal root ganglia. Optical images obtained from isolated whole embryonic and neonatal ganglia revealed a marked variability i...

journal_title：Brain research

authors： Utzschneider DA,Rand MN,Waxman SG,Kocsis JD

更新日期：1994-01-28 00:00:00

abstract：:This study determined if vasopressin generates superoxide anion (O2(-)) in a cyclooxygenase dependent manner and if such production contributes to impairment of dilation to activators of ATP sensitive K(+) (K(ATP)) and calcium sensitive K(+) (K(ca)) channels following fluid percussion brain injury (FPI) in newborn pig...

journal_title：Brain research

authors： Armstead WM

更新日期：2001-08-10 00:00:00

abstract：:Seasonally breeding animals undergo numerous physiological changes in response to changes in the length of the photoperiod. In most warm-weather breeding rodents, these changes result in reproductive quiescence during short photoperiods. It has been hypothesized that this change is mediated by changes in the activity ...

journal_title：Brain research

authors： Mintz EM,Lavenburg KR,Blank JL

更新日期：2007-11-14 00:00:00

abstract：:Social plasticity is the ability to adaptively change the expression of social behaviour according to experience, allowing animals to optimize their social relationships in the context of previous experience and the complexities of social environments. Environmental enrichment (EE) mimics a stimulating lifestyle at th...

journal_title：Brain research

authors： Gubert C,Hannan AJ

更新日期：2019-08-15 00:00:00

abstract：:It has recently been shown that the immunosuppressant cyclosporin A (CsA) dramatically ameliorates the selective neuronal necrosis which results from 10 min of forebrain ischemia in rats. Since CsA is a virtually specific blocker of the mitochondrial permeability transition (MPT) pore which is assembled under adverse ...

journal_title：Brain research

authors： Li PA,Uchino H,Elmér E,Siesjö BK

更新日期：1997-04-04 00:00:00

abstract：:In the context of injury to the corticospinal tract (CST), brainstem-origin circuits may provide an alternative system of descending motor influence. However, subcortical circuits are largely under subconscious control. To improve volitional control over spared fibers after CST injury, we hypothesized that a combinati...

journal_title：Brain research

authors： Harel NY,Yigitkanli K,Fu Y,Cafferty WB,Strittmatter SM

更新日期：2013-11-13 00:00:00

abstract：:Immunohistochemical and neuronal tracing methods were used in cats to determine which type of postganglionic sympathetic neuron is innervated by preganglionic neurons which contain corticotrophin releasing factor-like immunoreactivity (CRF-LI). Preganglionic neurons with CRF-LI have their cell bodies at two restricted...

journal_title：Brain research

authors： Shafton AD,Oldfield BJ,McAllen RM

更新日期：1992-12-25 00:00:00

abstract：:The mesencephalic reticular formation (MRF) of cats anesthetized with N2O was stimulated electrically, and the effects of this stimulation on activity in the striate cortex were studied. The variations of intra- and extracellularly recorded unit activity and the changes in the extracellular potassium concentration wer...

journal_title：Brain research

authors： Singer W,Tretter F,Cynader M

更新日期：1976-01-30 00:00:00

abstract：:Met-enkephalin immunoreactive material content was found to be decreased in the cervical and thoracic segments of the spinal cord from rats aged 25 months as compared to young, 3-month-old, rats. No age-related variations were detectable at the lumbar level. Bio-Gel P 30 column chromatography of thoracic segment extra...

journal_title：Brain research

authors： Missale C,Govoni S,Castelletti L,Spano PF,Trabucchi M

更新日期：1983-02-28 00:00:00

abstract：:The amount of myelin and its protein composition was studied in hypothyroid rats during the first 30 days after birth. Although the brain weight was 92% of that in the controls, the yield of myelin in hypothyroid animals was only 60% of that in controls. The protein and glycoprotein ocmposition of the isolated myelin ...

journal_title：Brain research

authors： Matthieu JM,Reier PJ,Sawchak JA

更新日期：1975-02-14 00:00:00

abstract：:Astrocytes produce and bind endothelins (ETs), suggesting that these cells have ET autoregulatory and eliminatory functions. To further investigate these functions in primary rat astrocytes, ET-1 levels in the cell culture media (RIA/HPLC) and intracellular content of ET-1 mRNA (RT PCR) were measured under basal and s...

journal_title：Brain research

authors： Hasselblatt M,Kamrowski-Kruck H,Jensen N,Schilling L,Kratzin H,Sirén AL,Ehrenreich H

更新日期：1998-03-02 00:00:00

abstract：:The role of the lateral parabrachial area (lPB) in the acquisition of a delayed taste aversion learning task (TAL) was examined by delivering the peripherally acting aversive compound, methylscopolamine (MSP), through two different routes, intraperitoneal and intraventricular. Consistent with previous anatomical, beha...

journal_title：Brain research

authors： Cubero I,Puerto A

更新日期：2000-07-14 00:00:00

abstract：:Behavioral studies have shown that the hyperalgesia arising from inflammatory agents, such as prostaglandin E(2) (PGE(2)), can be antagonized by activators of the ATP-sensitive potassium current (K(ATP)). This observation raises questions as to whether this suppression results from a direct action on sensory neurons a...

journal_title：Brain research

authors： Chi XX,Jiang X,Nicol GD

更新日期：2007-05-11 00:00:00

abstract：:Cocaine increases dopamine concentration in the nucleus accumbens through competitive binding to the dopamine transporter (DAT). However, it also increases the frequency of dopamine release events, a finding that cannot be explained by action at the DAT alone. Rather, this effect may be mediated by cocaine-induced mod...

journal_title：Brain research

authors： Gerth AI,Alhadeff AL,Grill HJ,Roitman MF

更新日期：2017-01-15 00:00:00

abstract：:Axonal projections of ganglion cells to the superior colliculus (SC) and to the nucleus of the optic tract (NOT) were re-examined physiologically in the cat's retina. Taking care to minimize current spreads around the stimulating electrodes placed in the NOT or the SC, we reached a conclusion that a substantial propor...

journal_title：Brain research

authors： Sawai H,Fukuda Y,Wakakuwa K

更新日期：1985-08-19 00:00:00

abstract：BACKGROUND:Diminished dopaminergic neurotransmission contributes to decreased reward and negative eating behaviors in obesity. Bariatric surgery is the most effective therapy for obesity and rapidly reduces hunger and improves satiety through unknown mechanisms. We hypothesized that dopaminergic neurotransmission would...

journal_title：Brain research

authors： Dunn JP,Cowan RL,Volkow ND,Feurer ID,Li R,Williams DB,Kessler RM,Abumrad NN

更新日期：2010-09-02 00:00:00

abstract：:Aromatization of testosterone in the preoptic area of the male ring dove is required for the expression of specific estrogen-sensitive sexual behavior. Estradiol metabolism and/or binding of the aromatization product(s) to the preoptic estrogen receptors (ER) could interfere with the apparent increase in estradiol for...

journal_title：Brain research

authors： Steimer T,Hutchison JB

更新日期：1989-02-20 00:00:00

abstract：:We have previously shown that systemic administration of non-selective dopamine agonists results in a pronounced expression of the proto-oncoprotein Fos within the lateral habenula. In the current study we examined the effects of selective D1 and D2 dopamine receptor agonists on habenular Fos expression. Rats were inj...

journal_title：Brain research

authors： Wirtshafter D,Krebs JC

更新日期：1997-03-07 00:00:00

abstract：:Putative N-type voltage-sensitive calcium channels were localized autoradiographically in thaw-mounted rat brain slices using [125I]omega-conotoxin GVIA as a ligand. Density of the toxin binding sites were highly heterogeneous throughout the brain. The highest density of the binding sites was observed in the glomerula...

journal_title：Brain research

authors： Takemura M,Kiyama H,Fukui H,Tohyama M,Wada H

更新日期：1988-06-07 00:00:00

abstract：:The purpose of the present study is to examine the effects of mental fatigue and motivation on neural network dynamics activated during task switching. Mental fatigue was induced by 2 h of continuous performance; after which subjects were motivated by using social comparison and monetary reward as motivating factors t...

journal_title：Brain research

authors： Lorist MM,Bezdan E,ten Caat M,Span MM,Roerdink JB,Maurits NM

更新日期：2009-05-13 00:00:00

abstract：:One of the fundamental tasks of neurobiology is to understand how the precision and specificity of the adult nervous system is achieved during development. This paper reviews the progress that has been made toward this end in studies of the developing mammalian cerebral cortex. Particular attention is focused on the p...

journal_title：Brain research

authors： McConnell SK

更新日期：1988-01-01 00:00:00

abstract：:Male laboratory rats were raised in two colonies, each of 27 rats, and then given intraventricular injections of the norepinephrine neurotoxin 6-hydroxydopamine (6-OHDA) or the serotonin neurotoxin 5,6-dihydroxytryptamine (5,6-DHT) or saline. They were then returned to their enclosure and behavior during the next 50 d...

journal_title：Brain research

authors： Ellison G

更新日期：1976-02-13 00:00:00

abstract：:The primary olfactory cortex of mouse embryos varying in age from the 13th to the 15th day of gestation is investigated with the aid of several techniques: Nissl and Golgi preparations, autoradiography and electron microscopy. It is observed that the earliest cells to complete their migrations are diffusely scattered ...

journal_title：Brain research

authors： Derer P,Caviness VS Jr,Sidman RL

更新日期：1977-03-04 00:00:00

abstract：:Spinal muscular atrophy is caused by deletions or mutations in the SMN1 gene that result in reduced expression of the SMN protein. The SMN protein is an essential molecular chaperone that is required for the biogenesis of multiple ribonucleoprotein (RNP) complexes including spliceosomal small nuclear RNPs (snRNPs). Re...

journal_title：Brain research

authors： Beattie CE,Kolb SJ

更新日期：2018-08-15 00:00:00

abstract：:Nuclear factor κB (NFκB) signaling plays ubiquitous roles in inflammation, immune response and neurogenesis. G protein-coupled receptor kinase 5 (GRK5) can protect neurons from degeneration. GRK5 also mediates tumor necrosis factor-α (TNFα)-induced NFκB signaling through the phosphorylation of IκBα. Here, we show that...

journal_title：Brain research

authors： Zhang Y,Shen GL,Shangguan LJ,Yu Y,He ML

更新日期：2015-05-22 00:00:00

abstract：:The effects of adenosine and the adenosine binding enhancer, PD 81,723, on low magnesium-induced bursting in the in vitro hippocampal slice were examined. Extracellular recordings were obtained from the CA3 pyramidal cell layer while electrically stimulating in the stratum radiatum under low magnesium perfusion. Adeno...

journal_title：Brain research

authors： Janusz CA,Berman RF

更新日期：1993-08-13 00:00:00