Abstract：
:The role of the lateral parabrachial area (lPB) in the acquisition of a delayed taste aversion learning task (TAL) was examined by delivering the peripherally acting aversive compound, methylscopolamine (MSP), through two different routes, intraperitoneal and intraventricular. Consistent with previous anatomical, behavioral and molecular work, electrolytic lesions centered at the lPB did impair TAL when the MSP was injected intraperitoneally. However, lPB-lesioned animals exhibited intact learning capacities when MSP was administered intraventricularly. These results are interpreted in terms of the lPB as a critical anatomical relay involved in bottom-up visceral processing of aversive stimuli and also in relation to the relevance of forebrain structures in TAL.
journal_name
Brain Resjournal_title
Brain researchauthors
Cubero I,Puerto Adoi
10.1016/s0006-8993(00)02453-7subject
Has Abstractpub_date
2000-07-14 00:00:00pages
113-9issue
1eissn
0006-8993issn
1872-6240pii
S0006-8993(00)02453-7journal_volume
871pub_type
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