Abstract：
:Ethanol administration in long-sleep (LS) and short-sleep (SS) mice results in a large number of Fos-IR neurons in the supraoptic nucleus (SON) in LS, and almost no Fos-IR neurons in the same nucleus in SS mice. In contrast, isotonic saline, hypertonic saline, with or without ethanol, resulted in a similar pattern of Fos-IR in both strains. These data indicate a differential effect of ethanol on c-Fos signaling specifically in the SON. Since the LS and SS mice were specifically selected for differential sensitivity to the sedative/hypnotic effects of ethanol, this differential in c-Fos activity may be causally implicated in their differential sensitivity to ethanol.
journal_name
Brain Resjournal_title
Brain researchauthors
Eisenman LM,Donovan HS,Johnson TEdoi
10.1016/s0006-8993(02)02453-8subject
Has Abstractpub_date
2002-05-10 00:00:00pages
114-7issue
1-2eissn
0006-8993issn
1872-6240pii
S0006899302024538journal_volume
935pub_type
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