Interaction of calmodulin inhibitors and protein kinase C inhibitors with voltage-dependent calcium channels.

abstract：:Primary gaze fixation in healthy individuals is frequently interrupted by microsaccades and saccadic intrusions (SI). The neural systems responsible for the control of attention and eye movements are believed to overlap and in line with this, the behaviour of microsaccades appears to be affected by exogenous and endog...

journal_title：Brain research

authors： Gowen E,Abadi RV,Poliakoff E,Hansen PC,Miall RC

更新日期：2007-04-13 00:00:00

abstract：:Tyrosine hydroxylase phenotype expression was investigated in the catecholaminergic population of the locus coeruleus neurons of two pure inbred mouse strains, Balb/C and C57Black/6. Therefore, we have characterized the precise organization of tyrosine hydroxylase-expressing perikarya population, in control animals an...

journal_title：Brain research

authors： Ginovart N,Marcel D,Bezin L,Garcia C,Gagne C,Pujol JF,Weissmann D

更新日期：1996-05-20 00:00:00

abstract：:Proactive motor response inhibition is used to strategically restrain actions in preparation for stopping. In this study, we first examined the event related potential (ERP) elicited by low and high level of proactive response inhibition, as assessed by the stop-signal task. Corroborating previous studies, we found an...

journal_title：Brain research

authors： Brevers D,Cheron G,Dahman T,Petieau M,Palmero-Soler E,Foucart J,Verbanck P,Cebolla AM

更新日期：2020-11-15 00:00:00

abstract：:Following a mild cortical impact injury delivered by a piston to the right sensorimotor cortex of the anesthetized rat, we evaluated mantle loss, neuronal changes, and fiber track degeneration by deOlmos silver stains up to 8 weeks after injury. Darkened neurons indicating damage (chromatolysis) occurred widely throug...

journal_title：Brain research

authors： Matthews MA,Carey ME,Soblosky JS,Davidson JF,Tabor SL

更新日期：1998-05-25 00:00:00

abstract：:Spreading depression (SD) is characterized by a transient breakdown of neuronal function concomitant with a massive failure of ion homeostasis. It is a phenomenon that can be induced in neocortical tissue by raising excitability, e.g. injection of K(+), application of glutamatergic agonists, or blocking Na(+)/K(+) ATP...

journal_title：Brain research

authors： Köhling R,Koch UR,Hagemann G,Redecker C,Straub H,Speckmann EJ

更新日期：2003-06-13 00:00:00

abstract：:Fetal mouse retinal ganglion cell axons have been shown to ramify within co-cultured basement membrane secreting tumor explants and upon isolated basement membranes. Here we report that laminin, a glycoprotein found in basement membranes and adhesion sites of a variety of cell types, acted as a substrate for retinal e...

journal_title：Brain research

authors： Smalheiser NR,Crain SM,Reid LM

更新日期：1984-01-01 00:00:00

abstract：:The present study reveals developmental changes in the number, the phenotype and the distribution pattern of mast cells (MCs) along the cervical, the thoracic and the lumbar parts of the spinal dura mater. Postnatal infiltration of spinal dura by MCs does not appear to follow a sequential developmental pattern and men...

journal_title：Brain research

authors： Michaloudi H,Batzios C,Chiotelli M,Grivas I,Papadopoulos GC

更新日期：2008-08-21 00:00:00

abstract：:Primary open angle glaucoma (POAG) is a leading cause of irreversible blindness worldwide. Previous MRI studies have revealed that POAG can be associated with alterations in hippocampal function. Thus, the aim of this study was to investigate a relationship between chronic high intraocular pressure (IOP) and hippocamp...

journal_title：Brain research

authors： Yuan Y,Chen Z,Li L,Li X,Xia Q,Zhang H,Duan Q,Zhao Y

更新日期：2017-11-15 00:00:00

abstract：:Bcl-2 has been hypothesized to regulate many cellular functions in addition to its well-characterized role in the prevention of programmed cell death. To understand the role of Bcl-2 in regulating cell morphology and to explore the mechanism of this effect, we examined the effects of Bcl-2 overexpression on the morpho...

journal_title：Brain research

authors： Mi Z,Mirnics ZK,Schor NF

更新日期：2006-09-27 00:00:00

abstract：:The ability of the monoclonal antibody, 192-IgG, directed against the rat nerve growth factor (NGF) receptor to mimic or inhibit the actions of NGF was examined in vitro and in vivo. 192-IgG had no effect on morphology, survival, or protein synthesis rates of sympathetic neuronal cultures. When injected into newborn r...

journal_title：Brain research

authors： Johnson EM Jr,Osborne PA,Taniuchi M

更新日期：1989-01-23 00:00:00

abstract：:The Thy-1 antigen is a cell surface glycoprotein found in neural tissue of all mammalian species so far studied. The distribution and amount of this antigen has been measured on 4 human neuronal and 2 neuroglial cell lines and on fresh tumour cells of neuronal origin. In 3 out of 4 neuronal lines (LAN-1, TR14, CHP 212...

journal_title：Brain research

authors： Kemshead JT,Ritter MA,Cotmore SF,Greaves MF

更新日期：1982-03-25 00:00:00

abstract：:The role of the cerebellum and the red nucleus in the conditioned eyeblink response was assessed, using a combination of reversible lesions and multiple-unit extracellular recording in the awake, behaving rabbit. Lesion, recording, and stimulation experiments have indicated that both of these structures are involved i...

journal_title：Brain research

authors： Chapman PF,Steinmetz JE,Sears LL,Thompson RF

更新日期：1990-12-24 00:00:00

abstract：:By ligating specific nerves in the cat, the central processes of the nodose ganglion (NG) cells containing substance P-like immunoreactive materials were shown, immunohistochemically, to run through the cross-anastomosis made between the cranial end of the NG and the caudal end of the superior cervical ganglion (SCG),...

journal_title：Brain research

authors： Hayashi H,Ohsumi K,Fujiwara M,Mizuno N

更新日期：1983-06-27 00:00:00

abstract：:A terminal transferase-mediated dUTP nick end labeling (TUNEL) method was utilized for detection of neuronal death in the subcortical relay nuclei of the trigeminosensory system following the infraorbital nerve transection in newborn rats. At 18-24 h after injury, numerous TUNEL-positive profiles were found within the...

journal_title：Brain research

authors： Sugimoto T,Xiao C,Takeyama A,He YF,Takano-Yamamoto T,Ichikawa H

更新日期：1999-04-10 00:00:00

abstract：:Increasing adult neurogenesis in the hippocampal formation (HF) has been proposed as a potential foundation for neuronal repair in Alzheimer's disease (AD), but the evidence remains controversial. We used P8 strain of senescence-accelerated mice (SAMP8) as a model of AD to investigate changes in adult neurogenesis. We...

journal_title：Brain research

authors： Gang B,Yue C,Han N,Xue H,Li B,Sun L,Li X,Zhao Q

更新日期：2011-05-10 00:00:00

abstract：:Cyclic AMP is a second messenger by which different extracellular signals are transduced into biological responses. Within the cell, most of the effects of cAMP are mediated through the cAMP protein kinase which appears to be localized in specific compartments of the cell near to their substrate proteins. In the prese...

journal_title：Brain research

authors： Perez J,Tinelli D,Cagnoli C,Pecin P,Brunello N,Racagni G

更新日期：1993-01-29 00:00:00

abstract：:The delay associated with cerebral processing time implies a lack of real-time representation of changes in the observed environment. To bridge this gap for motor actions in a dynamical environment, the brain uses predictions of the most plausible future reality based on previously provided information. To optimise th...

journal_title：Brain research

authors： Beudel M,Leenders KL,de Jong BM

更新日期：2016-12-01 00:00:00

abstract：:Little is known about the cells or mechanisms of O2 chemoreception in vertebrates other than mammals. The purpose of this study, therefore, was to identify O2-sensitive chemoreceptors in a fish. Putative O2-sensitive chemoreceptors were dissociated from the gills of channel catfish, Ictalurus punctatus, and cultured. ...

journal_title：Brain research

authors： Burleson ML,Mercer SE,Wilk-Blaszczak MA

更新日期：2006-05-30 00:00:00

abstract：:The time-course of intracellular glutathione (GSH) values after incubation with L-buthionine-(S,R)-sulfoximine (BSO), a selective inhibitor of gamma-glutamylcysteine synthetase, showed that glutathione turns over with a half-life of 5 h. Intracellular GSH was assayed by flow cytometry using three different methods. As...

journal_title：Brain research

authors： Devesa A,O'Connor JE,Garciá C,Puertes IR,Viña JR

更新日期：1993-08-06 00:00:00

abstract：:The recent indications of specialized lateralization of cardiovascular regulation within the right and left posterior insular cortex of the rat, suggest the possibility of transcallosal connectivity between these regions. This has not been previously demonstrated using physiological techniques. Extracellular neural re...

journal_title：Brain research

authors： Zhang Z,Oppenheimer SM

更新日期：2000-04-28 00:00:00

abstract：:Altered dopamine regulation in the medial prefrontal cortex has been linked to drug abuse and disorders such as schizophrenia. Heterogeneous expression of the dopamine transporter, as well as the ability of the norepinephrine transporter to clear dopamine in the prefrontal cortex, delineates two potential sites for th...

journal_title：Brain research

authors： Mazei MS,Pluto CP,Kirkbride B,Pehek EA

更新日期：2002-05-17 00:00:00

abstract：:We investigated the influence of muramyl dipeptide (MDP), a cell wall component of Gram-positive bacteria, on cytokine-induced nitric oxide (NO) production in rat primary astrocytes. MDP alone did not induce NO release in astrocyte cultures. However, MDP increased astrocyte NO production and subsequent nitrite accumul...

journal_title：Brain research

authors： Trajkovic V,Samardzic T,Stosic-Grujicic S,Ramic Z,Mostarica Stojkovic M

更新日期：2000-11-10 00:00:00

abstract：:Previous studies have suggested that cardiovascular responses elicited by injection of glycine into the nucleus tractus solitarii (NTS) depend upon interactions between glycinergic and cholinergic neuronal elements in NTS. Release of acetylcholine in response to glycine is one such interaction that has been shown in s...

journal_title：Brain research

authors： Talman WT,Wellendorf L,Martinez D,Ellison S,Li X,Cassell M,Ohta H

更新日期：1994-07-11 00:00:00

abstract：:Melatonin is a hormone that mostly produced from the pineal gland, and it performs as a strong neuroprotectant to both neuron and glial cells against methamphetamine (METH)-induced neurotoxicity. Recently, it has been found that METH also damages the blood brain barrier (BBB) structure and function. However, the prote...

journal_title：Brain research

authors： Jumnongprakhon P,Govitrapong P,Tocharus C,Tocharus J

更新日期：2016-11-01 00:00:00

abstract：:Averaged evoked potentials and unitary discharges in response to tooth pulp and acoustic click stimuli were recorded from the hippocampus of freely moving rats. The spatial distribution of evoked field responses to tooth pulp stimulation and acoustic clicks were identical. Averaged evoked potentials consisted of a lar...

journal_title：Brain research

authors： Brankack J,Buzsáki G

更新日期：1986-07-23 00:00:00

abstract：:Administration of sheep red blood cells (10(6) cells, i.p.) resulted in central norepinephrine (NE) and dopamine (DA) changes which corresponded with the time of the peak immune response. These amine variations, however, appeared to be specific to certain brain regions. The increased accumulation of the NE metabolite,...

journal_title：Brain research

authors： Zalcman S,Shanks N,Anisman H

更新日期：1991-08-23 00:00:00

abstract：:Pretreatment with the alpha(2)-adrenoceptor agonist clonidine (31.25, 62.5, or 125 microg/kg, i.p.) dose-dependently reduced long-term potentiation (LTP) elicited in vivo in the occipital cortex of anesthetized rats, whereas pretreatment with the alpha(2)-adrenoceptor antagonist yohimbine (0.133, 0.4, or 1.2 mg/kg, i....

journal_title：Brain research

authors： Mondaca M,Hernández A,Pérez H,Valladares L,Sierralta W,Fernández V,Soto-Moyano R

更新日期：2004-09-24 00:00:00

abstract：:Inorganic mercury (Hg2+) reduced voltage-gated calcium channel currents irreversibly in two different preparations. In cultured rat dorsal root ganglion (DRG) neurons, studied with the whole cell patch clamp technique, a rapid concentration-dependent decrease in the L/N-type currents to a steady state was observed wit...

journal_title：Brain research

authors： Pekel M,Platt B,Büsselberg D

更新日期：1993-12-31 00:00:00

abstract：:The phonemic merger is a unique phenomenon which is referred to as acoustically very different phonemes are recognized as the same phoneme. In our previous study, we demonstrated that the merged speakers had lost the ability to discriminate the merged phonemes pre-attentively, as revealed by their failure in mismatch ...

journal_title：Brain research

authors： Tang M,Huang ZL,Zhong F,Xiang JL,Wang XD

更新日期：2020-08-01 00:00:00

abstract：:Neurointermediate lobes of rats comprise elements which, when excited in vitro, bring about an inhibition of the release of melanocyte stimulating hormone (MSH). Superfusion of neurointermediate lobes of intact donor rats with medium containing 45 mM K+ induced a stimulation of the release of oxytocin, arginine-vasopr...

journal_title：Brain research

authors： Tilders FJ,van der Woude HA,Swaab DF,Mulder AH

更新日期：1979-08-10 00:00:00