Focal axonal swellings in rat cerebellar Purkinje cells during normal development.

Abstract:

:Focal axonal swellings are characteristic of a wide range of neuropathies. Three neuron-specific monoclonal antibodies have been used to identify focal axonal swellings in the normal developing rat cerebellar cortex. Between 7 and 15 days postnatal, swellings are a common feature of the granular layer and white matter tracts. Using a Purkinje cell-specific antibody, the majority of swellings were shown to occur in Purkinje cell axons. Focal axonal swellings therefore seem to be a normal adjunct of Purkinje cell maturation.

journal_name

Brain Res

journal_title

Brain research

authors

Gravel C,Leclerc N,Plioplys A,Hawkes RB

doi

10.1016/0006-8993(86)91018-8

subject

Has Abstract

pub_date

1986-01-22 00:00:00

pages

325-32

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(86)91018-8

journal_volume

363

pub_type

杂志文章
  • Effects of aging on strategic-based visuomotor learning.

    abstract::There are different kinds of visuomotor learnings. One of the most studied is error-based learning where the information about the sign and magnitude of the error is used to update the motor commands. However, there are other instances where subjects show visuomotor learning even if the use of error sign and magnitude...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2015.05.022

    authors: Alfonso Uresti-Cabrera L,Vaca-Palomares I,Diaz R,Beltran-Parrazal L,Fernandez-Ruiz J

    更新日期:2015-08-27 00:00:00

  • Neurochemical evidence that AMPA receptor-mediated tonic inhibition of hypothalamic dopaminergic neurons occurs via activation of inhibitory interneurons.

    abstract::Blockade of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors with 6-nitro-7-sulfamoyl-benzo-[f]quinoxaline-2,3(1H,4H)-dione (NBQX) activates tuberoinfundibular (TIDA) and periventricular-hypophysial dopaminergic (PHDA) neurons suggesting that these neurons are tonically inhibited by endogenous...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)91305-6

    authors: Wagner EJ,Moore KE,Lookingland KJ

    更新日期:1994-10-17 00:00:00

  • Differential labelling of primary olfactory system subcomponents by SBA (lectin) and NADPH-d histochemistry in the frog Pipa.

    abstract::SBA and NADPH-d histochemistries allow identification of functionally distinct components of the amphibian primary olfactory system. In Pipa, a secondarily aquatic frog, combination of both methodologies, using alternate sets of histological sections, reveals that, apart from Jacobson's organ, this species has a "wate...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00507-6

    authors: Meyer DL,Fackler IR,Jadhao AG,D'Aniello B,Kicliter E

    更新日期:1997-07-11 00:00:00

  • Serotonin axon terminals in the ventral tegmental area of the rat: fine structure and synaptic input to dopaminergic neurons.

    abstract::The serotoninergic (5-hydroxytryptamine, 5-HT) innervation of the rat ventral tegmental area (VTA) was examined by light and electron microscopic radioautography following intraventricular infusion of [3H]5-HT. The [3H]5-HT labeled processes were characterized with respect to their regional distribution, ultrastructur...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(87)91588-5

    authors: Hervé D,Pickel VM,Joh TH,Beaudet A

    更新日期:1987-12-01 00:00:00

  • Enhancement of REM sleep with auditory stimulation in young and old rats.

    abstract::Auditory stimulation applied during rapid eye movement (REM) sleep enhances the duration of REM sleep in cats and humans. The present experiment investigated whether auditory stimulation would enhance REM sleep in young (3-6 months) rats, and also in old (22-24 months) rats which have impaired REM sleep. Baseline slee...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)91299-t

    authors: Arankowsky-Sandoval G,Stone WS,Gold PE

    更新日期:1992-09-04 00:00:00

  • Lesions and reversible inactivation of the dorsolateral caudate-putamen impair cocaine-primed reinstatement to cocaine-seeking in rats.

    abstract::Recent evidence suggests that cocaine addiction may involve progressive drug-induced neuroplasticity of the dorsal striatum. Here, we examined the effects of a) dorsolateral caudate putamen (dlCPu) lesions on cocaine self-administration, extinction of responding, and subsequent reinstatement to cocaine-seeking, and b)...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2011.08.030

    authors: Gabriele A,See RE

    更新日期:2011-10-12 00:00:00

  • Differential increases in P2X receptor levels in rat vagal efferent neurones following a vagal nerve section.

    abstract::Extracellular ATP can influence cells via activation of P2X purinoceptors, the distribution of which can be altered in the central and peripheral nervous systems following injury or tissue damage. Here we have investigated the effect of a unilateral section of the cervical vagus nerve on the distribution of P2X(1), P2...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(03)02797-5

    authors: Atkinson L,Shigetomi E,Kato F,Deuchars J

    更新日期:2003-07-04 00:00:00

  • Stress and electroconvulsive seizure differentially alter GPR56 expression in the adult rat brain.

    abstract::GPR56, a member of the G-protein-coupled receptor family, plays a role in the formation of the frontal and parietal brain lobes and cortical lamination in the embryonic stage. A recent report indicated the existence of GPR56 transcripts in the subventricular zone (SVZ) and hippocampal subgranular zone (SGZ) of the adu...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.09.020

    authors: Suzuki G,Kanda Y,Nibuya M,Hiramoto T,Tanaka T,Shimizu K,Watanabe Y,Nomura S

    更新日期:2007-12-05 00:00:00

  • Estrogen effects on tyrosine hydroxylase-immunoreactive cells in the ventral mesencephalon of the female rat: further evidence for the two cell hypothesis of dopamine function.

    abstract::The present study was undertaken to examine the differential effect of estrogen (E) on the expression of tyrosine hydroxylase (TH) in the substantia nigra compacta (SNc) and in two subdivisions of the ventral tegmental area in ovariectomized (ovx) and ovx plus estradiol benzoate (ovx+E)-treated female rats. Cell count...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02323-4

    authors: Zsarnovszky A,Scalise TJ,Horvath TL,Naftolin F

    更新日期:2000-06-23 00:00:00

  • On the relation between cerebral cysteinyl-leukotriene formation and epileptic seizures.

    abstract::In gerbils pentylenetetrazole- or handling-induced seizures were accompanied by cerebral formation of small amounts of cysteinyl-leukotrienes (LT) but large amounts of prostaglandin (PG) F2 alpha. By contrast, in rats injected with pentylenetetrazole or bicuculline very large amounts of PGF2 alpha but no cysteinyl-LT ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)90519-2

    authors: Simmet T,Tippler B

    更新日期:1991-02-01 00:00:00

  • Schwann cells can misdirect regrowing neuronal processes.

    abstract::Studies of potentials for dorsal spinal nerve root axons to regrow into the spinal cord involved placement of the tracer HRP/WGA-HRP on the cut end of the nerve root. Following this procedure, labeled neurons were found within the spinal dorsal gray matter. Analyses revealed that spinal neurons influenced by the prese...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00501-5

    authors: Sims TJ,Gilmore SA

    更新日期:1997-07-18 00:00:00

  • Non-peptide angiotensin II receptor antagonist and angiotensin-converting enzyme inhibitor: effect on a renin-induced deficit of a passive avoidance response in rats.

    abstract::Non-peptide receptor ligands with differential affinity for the angiotensin II-1 (AII-1) receptor (EXP3312, EXP3880) or the AII-2 receptor (PD123177) and an angiotensin converting enzyme (ACE) inhibitor captopril were evaluated for the ability to protect against a renin-induced performance deficit in a passive avoidan...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)91599-v

    authors: DeNoble VJ,DeNoble KF,Spencer KR,Chiu AT,Wong PC,Timmermans PB

    更新日期:1991-10-11 00:00:00

  • Myelin-associated glycoprotein (MAG) in myelin deficiency of caprine beta-mannosidosis.

    abstract::Caprine beta-mannosidosis is an inherited lysosomal storage disorder due to a deficiency of beta-mannosidase which cleaves beta-linked mannose residues from the ends of N-asparagine linked oligosaccharides of glycoproteins. Histological and chemical examination has revealed a deficiency of compact myelin in the brains...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90278-u

    authors: Sasaki M,Lovell KL,Möller JR

    更新日期:1993-08-20 00:00:00

  • Dexmedetomidine attenuated early brain injury in rats with subarachnoid haemorrhage by suppressing the inflammatory response: The TLR4/NF-κB pathway and the NLRP3 inflammasome may be involved in the mechanism.

    abstract::Early brain injury (EBI) plays a pivotal role in the prognosis of patients with subarachnoid haemorrhage (SAH). Dexmedetomidine (DEX), a highly selective α2 receptor agonist, is reported to exert multiple protective effects in many neurological diseases. This study was designed to investigate whether DEX had neuroprot...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2018.05.040

    authors: Yin D,Zhou S,Xu X,Gao W,Li F,Ma Y,Sun D,Wu Y,Guo Q,Liu H,Han L,Wang Z,Wang Y,Zhang J

    更新日期:2018-11-01 00:00:00

  • Organization of layers II-III connections in human visual cortex revealed by in vitro injections of biocytin.

    abstract::In the search for cortical mechanisms subserving psychological phenomena, a better understanding of human cortical circuitry is crucial. In this report we describe aspects of intrinsic connectivity of supragranular layers in human visual cortex, revealed by extracellular injections of the anterograde tracer biocytin i...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)91148-8

    authors: Kenan-Vaknin G,Ouaknine GE,Razon N,Malach R

    更新日期:1992-10-30 00:00:00

  • Brain 5-HT2 receptor binding sites in depressed suicide victims.

    abstract::5-HT2 receptor binding sites were measured (by saturation binding of [3H]ketanserin) in brain tissue obtained at postmortem from 19 suicide victims with definite evidence of depression and 19 sex and age-matched control subjects. Five of the suicide victims were receiving antidepressant drugs prior to death; 13 suicid...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)91621-6

    authors: Cheetham SC,Crompton MR,Katona CL,Horton RW

    更新日期:1988-03-08 00:00:00

  • Quantitative distribution of angiotensin-converting enzyme (kininase II) in discrete areas of the rat brain by autoradiography with computerized microdensitometry.

    abstract::We report the localization of angiotensin-converting enzyme (kininase II, EC 3.4.15.1) in discrete nuclei and areas of the rat brain by a quantitative autoradiographic technique using image processing coupled to computerized microdensitometry, after incubation of brain sections with the specific converting enzyme inhi...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(86)90746-8

    authors: Correa FM,Plunkett LM,Saavedra JM

    更新日期:1986-06-11 00:00:00

  • Voltage-gated K+ channel (Kv) subunit expression of the guinea pig spiral ganglion cells studied in a newly developed cochlear free-floating preparation.

    abstract::The spiral ganglion accommodates the cell bodies of the acoustic nerve fibres connecting the hair cells to the central nervous system. As the ionic channels containing various voltage-gated K+ channel (Kv) subunits play pivotal roles in determining the functional properties and firing behaviour of the spiral ganglion ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2008.02.072

    authors: Bakondi G,Pór A,Kovács I,Szucs G,Rusznák Z

    更新日期:2008-05-19 00:00:00

  • Intra-amygdalar okadaic acid enhances conditioned taste aversion learning and CREB phosphorylation in rats.

    abstract::Protein phosphatases (PPs) regulate many substrates implicated in learning and memory. Conditioned taste aversion (CTA) learning, in which animals associate a novel taste paired with a toxin and subsequently avoid the taste, is dependent on several serine/threonine phosphatase substrates and the PP1-binding protein sp...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2010.06.029

    authors: Oberbeck DL,McCormack S,Houpt TA

    更新日期:2010-08-12 00:00:00

  • Brain-derived neurotrophic factor stimulates survival and neuronal differentiation in cultured avian neural crest.

    abstract::The response of trunk neural crest cells taken from precise levels of the neural axis and cultured together with adjacent somites to Brain-derived neurotrophic factor (BDNF), was examined in cultures grown in a chemically defined medium. In control cultures, the number of neural crest-derived neurons expressing the HN...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0165-3806(88)90171-x

    authors: Kalcheim C,Gendreau M

    更新日期:1988-06-01 00:00:00

  • Appearance of melatonin receptors during embryonic life in Siberian hamsters (Phodopus sungorous).

    abstract::Maternal melatonin readily crosses the placenta to provide the fetus with time-of-day and day length information. To determine if melatonin could have a broader role during development than is currently recognized, melatonin receptor expression was examined in somatic sites during Siberian hamster embryogenesis. Using...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)91424-y

    authors: Rivkees SA,Reppert SM

    更新日期:1991-12-24 00:00:00

  • Effect of cerebral hemisphere decortication on the cytotoxic activity of natural killer and natural cytotoxic lymphocytes in the mouse.

    abstract::A comparison was made of the effects of left and right cerebral decortication on cytotoxic activity of natural killer and natural cytotoxic lymphocytes in the mouse. Natural killer cytotoxic activity was significantly reduced after right decortication, whereas left decortication led to a less pronounced, though still ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)90704-f

    authors: Belluardo N,Mudò G,Cella S,Bindoni M

    更新日期:1990-08-06 00:00:00

  • Oxidation of ion channels in the aging nervous system.

    abstract::Ion channels are integral membrane proteins that allow passive diffusion of ions across membranes. In neurons and in other excitable cells, the harmonious coordination between the numerous types of ion channels shape and propagate electrical signals. Increased accumulation of reactive oxidative species (ROS), and subs...

    journal_title:Brain research

    pub_type: 杂志文章,评审

    doi:10.1016/j.brainres.2016.02.046

    authors: Patel R,Sesti F

    更新日期:2016-05-15 00:00:00

  • Polyarthritis-associated changes in the opioid control of spinal CGRP release in the rat.

    abstract::As a model of chronic inflammatory pain, Freund's adjuvant-induced polyarthritis has been shown to be associated with marked alterations in the activity of opioid- and calcitonin gene-related peptide (CGRP)-containing neurons in the dorsal horn of the spinal cord in rats. Possible changes in the interactions between t...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(98)00350-3

    authors: Ballet S,Mauborgne A,Benoliel JJ,Bourgoin S,Hamon M,Cesselin F,Collin E

    更新日期:1998-06-15 00:00:00

  • Attenuation of neuroinflammation by dexmedetomidine is associated with activation of a cholinergic anti-inflammatory pathway in a rat tibial fracture model.

    abstract::Sustained neuroinflammation contributes to the pathogenesis of postoperative cognitive dysfunction. Dexmedetomidine, a selective α-2 adrenergic receptor agonist, exhibits a protective role in the brain. This study investigated whether dexmedetomidine pretreatment attenuates neuroinflammation induced by tibial fracture...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2016.04.074

    authors: Zhu YJ,Peng K,Meng XW,Ji FH

    更新日期:2016-08-01 00:00:00

  • Injection of bicuculline elicits firing of luteinizing hormone releasing hormone pulse generator in muscimol-treated ovariectomized rats.

    abstract::We have already demonstrated that, although exogenous gamma-aminobutyric acidA (GABAA) receptor agonist is capable of inhibiting the activity of luteinizing hormone releasing hormone (LHRH) pulse generator, the reduction in the endogenous GABAA receptor activity does not have a significant effect in ovariectomized rat...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)90145-7

    authors: Hiruma H,Sano A,Kimura F

    更新日期:1994-04-04 00:00:00

  • Influence of the Pro12Ala polymorphism of PPAR-gamma on age at onset and sRAGE levels in Alzheimer's disease.

    abstract::Peroxisome proliferator-activated receptor gamma (PPAR-gamma) has been described to have a role in the modulation of various genes involved in Abeta homeostasis, inflammation, and energy metabolism, making it a candidate gene for risk of Alzheimer's disease (AD). A functional polymorphism in exon 2 of the PPAR-gamma g...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2009.07.034

    authors: Yao L,Li K,Zhang L,Yao S,Piao Z,Song L

    更新日期:2009-09-29 00:00:00

  • The electrophysiological consequences of electrode impalement of peripheral nerves in the rat.

    abstract::Peripheral nerve fascicles are deliberately impaled during microneurography experiments. We have assessed conduction block under these circumstances. First we recorded compound action potentials (CAP) in the sural nerve following stimulation of the sciatic nerve. The insertion of injection and microneurography electro...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)91538-4

    authors: Rice AS,McMahon SB,Wall PD

    更新日期:1993-12-24 00:00:00

  • Expression of non-angiotensin II -125I-CGP 42112 binding sites on activated microglia after kainic acid induced neurodegeneration.

    abstract::[125I]CGP 42112, first developed to identify angiotensin II receptor subtype 2 (AT2), was recently shown to bind to a novel non-angiotensin binding site in injured rat brain tissue. We addressed the question whether non-angiotensin [125I]CGP 42112 binding appears after kainic acid induced hippocampal neurodegeneration...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)01035-3

    authors: Jöhren O,Viswanathan M,Saavedra JM

    更新日期:1995-12-08 00:00:00

  • ATP-sensitive chemoreceptors: antagonism by other nucleotides and the potential implications of ectonucleotidase activity.

    abstract::As measured by extracellular single-cell recording, the responses to adenosine triphosphate (ATP) by ATP-sensitive chemoreceptors (ATP cells) on the olfactory organ of the spiny lobster are markedly suppressed by adenosine diphosphate (ADP), adenosine monophosphate (AMP) and to a lesser extent, adenosine, when each is...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)90964-5

    authors: Gleeson RA,Carr WE,Trapido-Rosenthal HG

    更新日期:1989-09-11 00:00:00