Abstract:
:Focal axonal swellings are characteristic of a wide range of neuropathies. Three neuron-specific monoclonal antibodies have been used to identify focal axonal swellings in the normal developing rat cerebellar cortex. Between 7 and 15 days postnatal, swellings are a common feature of the granular layer and white matter tracts. Using a Purkinje cell-specific antibody, the majority of swellings were shown to occur in Purkinje cell axons. Focal axonal swellings therefore seem to be a normal adjunct of Purkinje cell maturation.
journal_name
Brain Resjournal_title
Brain researchauthors
Gravel C,Leclerc N,Plioplys A,Hawkes RBdoi
10.1016/0006-8993(86)91018-8subject
Has Abstractpub_date
1986-01-22 00:00:00pages
325-32issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(86)91018-8journal_volume
363pub_type
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