Effect of cerebral hemisphere decortication on the cytotoxic activity of natural killer and natural cytotoxic lymphocytes in the mouse.

Abstract:

:A comparison was made of the effects of left and right cerebral decortication on cytotoxic activity of natural killer and natural cytotoxic lymphocytes in the mouse. Natural killer cytotoxic activity was significantly reduced after right decortication, whereas left decortication led to a less pronounced, though still significant fall. The cytotoxic activity of natural cytotoxic cells, on the other hand, was significantly increased, particularly 15 days after left decortication. These findings mirror the results of previously published personal findings following electrothermocoagulation of the hypothalamus. The suggestion is made that the cortex and the hypothalamus form an integrated system for the control of certain aspects of natural immunity.

journal_name

Brain Res

journal_title

Brain research

authors

Belluardo N,Mudò G,Cella S,Bindoni M

doi

10.1016/0006-8993(90)90704-f

subject

Has Abstract

pub_date

1990-08-06 00:00:00

pages

297-302

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(90)90704-F

journal_volume

524

pub_type

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