Abstract：
:The dorsal lateral geniculate nucleus of tree shrews is very susceptible to the neurotoxic effects of kainic acid. In addition to neuronal loss, there is a profound loss of retinal terminals that is manifested through a disruption of anterograde transport of WGA/HRP from the retina to the kainic acid-lesioned area of the geniculate nucleus. The actions of kainic acid upon both the presynaptic terminals and geniculate neurons may be mediated by a glutamatergic pathway and questions the hypothesis that kainic acid is solely neuron-specific in its toxic action.
journal_name
Brain Resjournal_title
Brain researchauthors
Horn KM,Carey RGdoi
10.1016/0006-8993(87)91516-2subject
Has Abstractpub_date
1987-07-21 00:00:00pages
187-91issue
1eissn
0006-8993issn
1872-6240pii
0006-8993(87)91516-2journal_volume
416pub_type
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