The transthyretin gene is expressed in Schwann cells of peripheral nerves.

abstract：:Following lesions of the pyramidal tract in hamsters, retrograde changes were studied in the sensorimotor cortex and in the pyramidal tract axons proximal to the lesion, at survival times ranging from 2 weeks to 14 months. Severe cell shrinkage occurred in layer 5 pyramidal neurons as early as 2 weeks, but there was n...

journal_title：Brain research

authors： Kalil K,Schneider GE

更新日期：1975-05-16 00:00:00

abstract：:Explosive running is a reliable initial component of audiogenic seizures (AS) induced by acoustic stimulation in genetically prone rodents. This profound locomotor activation is usually considered as a convulsive manifestation of AS although some studies attribute running to a panic-like response. Increase in central ...

journal_title：Brain research

authors： Vinogradova LV,Shatskova AB,Tuomisto L

更新日期：2007-05-07 00:00:00

abstract：:Studies in regenerating goldfish optic nerves indicate that RNA may be axonally transported during optic nerve regeneration14,18,19. The present study was performed to determine if the axonal migration of RNA could be demonstrated during regeneration of the rat sciatic nerve. Rats, which had only the left sciatic nerv...

journal_title：Brain research

authors： Lindquist TD,Inogoglia NA

更新日期：1979-04-20 00:00:00

abstract：:The purpose of the present study is to examine the effects of mental fatigue and motivation on neural network dynamics activated during task switching. Mental fatigue was induced by 2 h of continuous performance; after which subjects were motivated by using social comparison and monetary reward as motivating factors t...

journal_title：Brain research

authors： Lorist MM,Bezdan E,ten Caat M,Span MM,Roerdink JB,Maurits NM

更新日期：2009-05-13 00:00:00

abstract：:Studies evaluating the role of steroid hormones in sexual differentiation of the zebra finch song system have produced complicated and at times paradoxical results, and indicate that additional factors may be critical. Therefore, in a previous study we initiated a screen for differential gene expression in the telence...

journal_title：Brain research

authors： Tang YP,Wade J

更新日期：2006-12-18 00:00:00

abstract：:The distribution of bFGF in mouse and rat retinas was established using an antibody generated against a rat specific bFGF sequence. The patterns established with this antibody were distinctly different in comparison to the immunostaining patterns using antibodies prepared against similar regions of bovine and human bF...

journal_title：Brain research

authors： Gao H,Hollyfield JG

更新日期：1992-07-10 00:00:00

abstract：:The mitochondrial respiratory chain is a powerful source of reactive oxygen species (ROS) also in noise induced hearing loss (NIHL) and anti-oxidants and free-radicals scavengers have been shown to attenuate the damage. Coenzyme Q(10) (CoQ(10)) or ubiquinone has a bioenergetic role as a component of the mithocondrial ...

journal_title：Brain research

authors： Fetoni AR,Piacentini R,Fiorita A,Paludetti G,Troiani D

更新日期：2009-02-27 00:00:00

abstract：:In extracellular recordings from chloral hydrate anesthetized rats the 5-HT3 antagonist, BRL 46470A, failed to prevent or reverse the increase in dopamine cell firing rate produced by systemic or iontophoretically applied morphine. A second 5-HT3 antagonist, tropesitron, was similarly found to be ineffective in antago...

journal_title：Brain research

authors： Gifford AN,Wang RY

更新日期：1994-02-28 00:00:00

abstract：:Pretreatment with the alpha(2)-adrenoceptor agonist clonidine (31.25, 62.5, or 125 microg/kg, i.p.) dose-dependently reduced long-term potentiation (LTP) elicited in vivo in the occipital cortex of anesthetized rats, whereas pretreatment with the alpha(2)-adrenoceptor antagonist yohimbine (0.133, 0.4, or 1.2 mg/kg, i....

journal_title：Brain research

authors： Mondaca M,Hernández A,Pérez H,Valladares L,Sierralta W,Fernández V,Soto-Moyano R

更新日期：2004-09-24 00:00:00

abstract：:A possible role for neuropeptides in affective disorders is suggested by many investigators. Somatostatin-like immunoreactivity (SS-LI) and neuropeptide Y-like immunoreactivity (NPY-LI) concentrations are demonstrated to be reduced in cerebrospinal fluid from depressed patients. We have shown that long-term treatment ...

journal_title：Brain research

authors： Kakigi T,Maeda K

更新日期：1992-12-18 00:00:00

abstract：:Prefrontal impairments have been hypothesized to be most strongly associated with the cognitive and emotional dysfunction in depression. Recently, white matter microstructural abnormalities in prefrontal lobe have been reported in elderly patients with major depressive disorder (MDD) using diffusion tensor imaging (DT...

journal_title：Brain research

authors： Li L,Ma N,Li Z,Tan L,Liu J,Gong G,Shu N,He Z,Jiang T,Xu L

更新日期：2007-09-07 00:00:00

abstract：:We investigated the effect of ketogenic diet (KD) on clusterin accumulation in the kainic acid (KA)-induced seizure model. Two days after KA administration, strong clusterin-like immunoreactivity (IR) was detected in the hippocampus in the normal diet (ND)-fed mice. But in the KD-fed mice, few clusterin-like IR was de...

journal_title：Brain research

authors： Noh HS,Kim DW,Kang SS,Cho GJ,Choi WS

更新日期：2005-04-25 00:00:00

abstract：:Frequency modulation (FM) is an important building block of complex sounds that include speech signals. Exploring the neural mechanisms of FM coding with computer modeling could help understand how speech sounds are processed in the brain. Here, we modeled the single unit responses of auditory neurons recorded from th...

journal_title：Brain research

authors： Chang TR,Chiu TW,Sun X,Poon PW

更新日期：2013-11-06 00:00:00

abstract：:The effects of psychological stress on catecholamine and indoleamine metabolism were examined in various brain regions of rats. Psychologically stressed rats were exposed to emotional responses of foot-shocked rats, but were themselves prevented from receiving foot-shock. Psychological stress for 30 min resulted in si...

journal_title：Brain research

authors： Kaneyuki H,Yokoo H,Tsuda A,Yoshida M,Mizuki Y,Yamada M,Tanaka M

更新日期：1991-08-23 00:00:00

abstract：:Deferoxamine (DFO) has shown therapeutic promise for the treatment of Parkinson׳s disease (PD) as it has reduced both behavioral and biochemical deficits when injected into the brain of rodent models of PD. Intranasally administered DFO targets the brain directly but non-invasively and has been effective in animal mod...

journal_title：Brain research

authors： Fine JM,Forsberg AC,Renner DB,Faltesek KA,Mohan KG,Wong JC,Arneson LC,Crow JM,Frey WH 2nd,Hanson LR

更新日期：2014-07-29 00:00:00

abstract：:This study determined whether macrophage inflammatory protein-1beta (MIP-1beta) plays a role in the hyperthermia caused by prostaglandin E2 (PGE2) given intracerebroventricularly (i.c.v.) in the rat. In these experiments, anti-murine MIP-1beta antibody (anti-MIP-1beta) was micro-injected in the anterior hypothalamic, ...

journal_title：Brain research

authors： Armengol JA,Benamar K,Fernández-Alonso A,Sancibrián M,Myers RD,Miñano FJ

更新日期：1997-02-14 00:00:00

abstract：:Bradykinin is known to rapidly elevate intracellular calcium leading to secretion of neurotransmitters and short term activation of tyrosine hydroxylase (TH). In this study we examined the effect of bradykinin on mRNA levels of two catecholamine biosynthetic enzymes. Treatment of PC12 cells with 1 microM bradykinin fo...

journal_title：Brain research

authors： Gebreyesus K,Kilbourne EJ,Sabban EL

更新日期：1993-04-16 00:00:00

abstract：:Fetal mouse retinal ganglion cell axons have been shown to ramify within co-cultured basement membrane secreting tumor explants and upon isolated basement membranes. Here we report that laminin, a glycoprotein found in basement membranes and adhesion sites of a variety of cell types, acted as a substrate for retinal e...

journal_title：Brain research

authors： Smalheiser NR,Crain SM,Reid LM

更新日期：1984-01-01 00:00:00

abstract：:Despite insights into an increasingly significant role for delta opioid receptors in thermoregulation, it is unclear whether delta receptors located in the brain or periphery play the more critical role in body temperature regulation. Moreover, it is not entirely clear which delta receptor phenotype, delta1 or delta2,...

journal_title：Brain research

authors： Rawls SM,Hewson JM,Inan S,Cowan A

更新日期：2005-07-05 00:00:00

abstract：:Social defeat is a powerful experience that often leads to drastic physiological and behavioral changes in many animal species. An example of such a change is conditioned defeat in Syrian hamsters. The neurophysiological mechanisms that underlie such changes are not yet fully understood, however, there is evidence tha...

journal_title：Brain research

authors： Jasnow AM,Huhman KL

更新日期：2001-11-30 00:00:00

abstract：:Chronic intermittent hypoxia (CIH) may cause sustained systemic hypertension by increasing sympathetic neural discharge (SND). We hypothesized that CIH alters brainstem circuits modulating SND. After 30 days of CIH exposure in rats, increased c-fos labeling was seen in the nucleus of the solitary tract and ventrolater...

journal_title：Brain research

authors： Greenberg HE,Sica AL,Scharf SM,Ruggiero DA

更新日期：1999-01-23 00:00:00

abstract：:Amyloid-beta protein (A beta) deposition in the cerebral vascular walls is one of the key features of Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis-Dutch type (HCHWA-D). A beta(1-40) carrying the 'Dutch' mutation (HCHWA-D A beta(1-40)) induces pronounced degeneration of cultured human brain p...

journal_title：Brain research

authors： Rensink AA,Verbeek MM,Otte-Höller I,ten Donkelaar HT,de Waal RM,Kremer B

更新日期：2002-10-11 00:00:00

abstract：:Physical activity has been related to antioxidant adaptations, which is associated with health benefits, including those to the nervous system. Additionally, available data suggest exercise and a caloric restriction regimen may reduce both the incidence and severity of neurological disorders. Therefore, our aim was to...

journal_title：Brain research

authors： Santin K,da Rocha RF,Cechetti F,Quincozes-Santos A,de Souza DF,Nardin P,Rodrigues L,Leite MC,Moreira JC,Salbego CG,Gonçalves CA

更新日期：2011-11-03 00:00:00

abstract：:The anatomical localization of nociceptin receptors was examined by in vitro quantitative autoradiography techniques in rat spinal cord sections by using [(125)I-Tyr(14)]nociceptin. [(125)I-Tyr(14)]nociceptin appeared to interact with a single class of binding sites (K(D)=0.1 nM) present in the grey matter in all lami...

journal_title：Brain research

authors： Gouardères C,Tafani JA,Meunier JC,Jhamandas K,Zajac JM

更新日期：1999-08-14 00:00:00

abstract：:In view of the use of synthetic propentofylline (PPF) as a protective agent in brain ischemia, its possible side effects on vision capacities have been explored by electroretinography in comparative experiments with theophylline. We used eyecup preparations of small-spotted dogfish sharks and of European eels, particu...

journal_title：Brain research

authors： Andjus RK,Konjević D,Damjanović I,Gacić Z

更新日期：2000-06-23 00:00:00

abstract：:Headache medicine is primarily dependent on patients' subjective reports of pain, which are assessed at diagnosis and throughout the duration of treatment. There is a need for an objective, quantitative biological measurement of headache pain severity. In this study, quantitative sensory testing (QST) was conducted vi...

journal_title：Brain research

authors： Nguyen RH,Ford S,Calhoun AH,Holden JK,Gracely RH,Tommerdahl M

更新日期：2013-03-01 00:00:00

abstract：:Previous studies indicate that 3-acetylpyridine (3-AP) intoxication produces discrete lesions of the inferior olive (IO) and other central structures in rats and mice. As a result, it has been widely employed in investigations of the influences of climbing fibers on cerebellar function. This study examines the central...

journal_title：Brain research

authors： Balaban CD

更新日期：1985-04-01 00:00:00

abstract：:Saccadic adaptation is the progressive correction of systematic saccade targeting errors. When a saccade to a particular target is adapted, saccades within a spatial window around the target, the adaptation field, are affected as a function of their distance from the adapted target. Furthermore, previous studies sugge...

journal_title：Brain research

authors： Collins T,Doré-Mazars K,Lappe M

更新日期：2007-10-03 00:00:00

abstract：:Exposure of hippocampal slices to Mg2+ free media (0 Mg) has been shown to trigger full production of stimulus-induced seizure activity after restoration of physiological conditions [1]. In the present study employing hippocampal entorhinal cortical slices (HEC), spontaneous epileptiform discharges (SEDs) were induced...

journal_title：Brain research

authors： Vick RS,Rafiq A,Coulter DA,Jakoi ER,DeLorenzo RJ

更新日期：1996-05-20 00:00:00

abstract：:A study was undertaken of the possible relationship of the binding affinity of a series of anticholinergic psychotomimetic drugs to their psychopharmacological and anticholinergic effects. Binding was measured to brain homogenates and nerve endings using [3H]quinuclidinyl benzilate (QB), a highly potent psychotomimeti...

journal_title：Brain research

authors： Baumgold J,Abood LG,Aronstam R

更新日期：1977-03-25 00:00:00