Abstract：
:We investigated the effect of ketogenic diet (KD) on clusterin accumulation in the kainic acid (KA)-induced seizure model. Two days after KA administration, strong clusterin-like immunoreactivity (IR) was detected in the hippocampus in the normal diet (ND)-fed mice. But in the KD-fed mice, few clusterin-like IR was detected. These results indicate that KD has neuroprotective effects throughout diminishing nuclear clusterin accumulation that is involved in caspase-3 independent cell death mechanism.
journal_name
Brain Resjournal_title
Brain researchauthors
Noh HS,Kim DW,Kang SS,Cho GJ,Choi WSdoi
10.1016/j.brainres.2005.01.097subject
Has Abstractpub_date
2005-04-25 00:00:00pages
114-8issue
1eissn
0006-8993issn
1872-6240pii
S0006-8993(05)00161-7journal_volume
1042pub_type
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