The effect of 5-HT3 receptor antagonists on the morphine-induced excitation of A10 dopamine cells: electrophysiological studies.

abstract：:Direct microinjection of cholinergic compounds into pontine reticular formation furnishes an excellent phenomenological model of the rapid eye movement phase of sleep (REM), but the mechanisms underlying this effect and whether they mimic the cellular events of natural REM remain unknown. Data presented here from intr...

journal_title：Brain research

authors： Greene RW,Gerber U,McCarley RW

更新日期：1989-01-02 00:00:00

abstract：:Relative preservation of dopaminergic axons in patches and a subcallosal layer was observed in the dorsal, lateral and caudal striatum 4 weeks after intrastriatal injection of 6-hydroxydopamine (6-OHDA), a neurotoxin selective for catecholaminergic neurons. Since calcium binding proteins are reported to provide neurop...

journal_title：Brain research

authors： Tsuboi K,Kimber TA,Shults CW

更新日期：2000-06-02 00:00:00

abstract：:PCP (10 mg/kg, s.c.) causes hypertension that is associated with decrease or tendency to decrease the levels of epinephrine and norepinephrine in the hypothalamus and the brainstem regions. If this represents a decreased catecholaminergic activity, then this may enhance sympathetic activity and contribute to the PCP-i...

journal_title：Brain research

authors： Bayorh MA,Zukowska-Grojec Z,Palkovits M,Kopin IJ

更新日期：1984-11-12 00:00:00

abstract：:Motoneurons in the lumbar spinal cord of chick embryos 6 days old, the age when their cell death starts, were labeled in vivo by retrograde axonal transport of horseradish peroxidase (HRP) and then cultured as cord fragments or isolated cells. In Eagle's minimum essential medium with no additives, spinal cord cells su...

journal_title：Brain research

authors： Tanaka H,Obata K

更新日期：1983-09-01 00:00:00

abstract：:Neurokinin A and B (NKA and NKB) and neuropeptide K (NPK) were recently isolated from porcine spinal cord and brain, and together with substance P (SP) considerably extend the list of tachykinin-like peptides present in the mammalian nervous system. In order to investigate the distribution of tachykinins in the centra...

journal_title：Brain research

authors： Arai H,Emson PC

更新日期：1986-12-10 00:00:00

abstract：:The present study examined if olfactory bulbectomy (OBX) altered defensive behaviors on the elevated plus-maze and the open-field differently in male and female rats. Similar increases in defensive behaviors in male and female rats were observed in both tests following OBX. No significant correlations were detected be...

journal_title：Brain research

authors： Stock HS,Hand GA,Ford K,Wilson MA

更新日期：2001-06-08 00:00:00

abstract：:The lipid, protein, acetylcholine and ATP content of cholinergic synaptic vesicles isolated from the richly innervated electric organ of Torpedo marmorata and purified to constant composition has been determined. The number of vesicles present in the preparations has been estimated by quantitative electron microscopy ...

journal_title：Brain research

authors： Ohsawa K,Dowe GH,Morris SJ,Whittaker VP

更新日期：1979-02-09 00:00:00

abstract：:Intracellular staining with recording micropipettes filled with a Procion yellow solution was attempted on 11 lateral geniculate neurons of chloralose-anesthetized cats for the purpose of correlating electrophysiologically identified cell types with morphologically identified cell types. Five neurons were successfully...

journal_title：Brain research

authors： Ogawa T,Takimori T,Takahashi Y

更新日期：1978-01-06 00:00:00

abstract：:Purpurin, a retina-specific protein, is known to play a role in cell adhesion during development of the chicken retina. Although purpurin has been significantly detected in adult chicken retina, its function in the matured retina is not well understood. Therefore, to determine the expression pattern of purpurin in the...

journal_title：Brain research

authors： Tanaka M,Murayama D,Nagashima M,Higashi T,Mawatari K,Matsukawa T,Kato S

更新日期：2007-06-11 00:00:00

abstract：:In vivo microdialysis techniques were used to examine the effects of estrogen on potassium-stimulated acetylcholine release in the hippocampus and overlying cortex of adult, ovariectomized rats. Estrogen treatment resulted in a significant increase in the percent change in acetylcholine release induced by potassium re...

journal_title：Brain research

authors： Gibbs RB,Hashash A,Johnson DA

更新日期：1997-02-21 00:00:00

abstract：:In the present study, temporal changes of voltage-gated Ca(2+) channel (VGCC) immunoreactivities were evaluated in the gerbil hippocampus following ischemia. P/Q-type VGCC immunoreactivity was elevated in the hippocampus in the 3 h post-ischemic group. In the 30 min post-ischemic group, N-type VGCC immunoreactivity be...

journal_title：Brain research

authors： Park SK,An SJ,Hwang IK,Suh JG,Oh YS,Won MH,Kang TC

更新日期：2003-04-25 00:00:00

abstract：:Auditory transients (such as sound onset or a frequency transition within a continuous sound) are assumed to parse the auditory input into smaller units enabling the formation of unitary sound representations separately for each segment. This was discovered by using the mismatch negativity (MMN) component of the event...

journal_title：Brain research

authors： Weise A,Bendixen A,Müller D,Schröger E

更新日期：2012-06-29 00:00:00

abstract：:NO (nitric oxide) produced in limbic brain regions has important roles in the regulation of autonomic nervous system and HPA axis activity, anxiety, fear learning, long-term memory formation, and depression. NO is synthesized from l-arginine in a reaction catalyzed by nitric oxide synthase (NOS). Neuronal nitric oxide...

journal_title：Brain research

authors： Keser A,Balkan B,Gozen O,Kanit L,Pogun S

更新日期：2011-01-12 00:00:00

abstract：:Single cell recordings were made from neurons in the lateral tegmental field of the medulla (LTFM) during electrical stimulation of the hypothalamic defense area (HDA) of the rabbit. Fifty-four cells were inhibited by HDA stimulation; 23 of these cells received barosensory input. Twenty-two LTFM cells showed an increa...

journal_title：Brain research

authors： Winters RW,McCabe PM,Green EJ,Duan YF,Schneiderman N

更新日期：1991-08-30 00:00:00

abstract：:The melanocortins (MC) can affect interscapular brown adipose tissue (IBAT) thermogenesis via its sympathetic nervous system (SNS) innervation. We chose a site of high MC4-receptor (MC4-R) mRNA co-localization with SNS outflow neurons to IBAT, the subzona incerta (subZI) to test whether IBAT thermogenesis could be inc...

journal_title：Brain research

authors： Vaughan CH,Shrestha YB,Bartness TJ

更新日期：2011-09-09 00:00:00

abstract：:Glutamate is an excitatory neurotransmitter implicated in the pathogenesis of psychiatric disorders. Glutamate results in the activation of an enzyme called glycogen synthase kinase-3 (GSK-3) acting through N-methyl-d-aspartate (NMDA) receptors. Impaired expression of GSK-3 affects behavior and neurochemicals level in...

journal_title：Brain research

authors： Walia V,Garg C,Garg M

更新日期：2019-02-01 00:00:00

abstract：:Many lines of evidence support the importance of the nucleus accumbens (NAC) for ethanol-reinforced behavior. The nature of the neuronal activity that occurs in this region during ethanol self-administration is not known. We recorded from ensembles of single-units primarily located within the shell of the NAC during o...

journal_title：Brain research

authors： Janak PH,Chang JY,Woodward DJ

更新日期：1999-01-30 00:00:00

abstract：:The present study compared Fos expression in identified hypothalamic magnocellular neurons in lactating and non-lactating female rats submitted to acute haemorrhage or 24 h of water deprivation, stimuli that induce the release of both oxytocin and vasopressin. Quantitative analysis of preparations doubly immunostained...

journal_title：Brain research

authors： Fénelon VS,Theodosis DT,Poulain DA

更新日期：1994-10-31 00:00:00

abstract：:We compared the relative abilities of a series of calmodulin inhibitors and protein kinase C inhibitors to influence 45Ca2+ influx through voltage-dependent Ca2+ channels in PC12, a clonal neural cell line. K+-depolarization-dependent 45Ca2+ uptake was reduced by the calmodulin inhibitors calmidazolium, trifluoperazin...

journal_title：Brain research

authors： Greenberg DA,Carpenter CL,Messing RO

更新日期：1987-02-24 00:00:00

abstract：:Monkeys made hemiparkinsonian by infusion of a solution of MPTP into one carotid artery appeared to ignore food presented from the contralateral side. Initial observations suggested neglect of visual stimuli presented as fruit treats by automated delivery system in the half-field contralateral to MPTP treatment. Furth...

journal_title：Brain research

authors： Bankiewicz KS,Oldfield EH,Plunkett RJ,Schuette WH,Cogan DG,Hogan N,Zuddas A,Kopin IJ

更新日期：1991-02-08 00:00:00

abstract：:Many of our daily movements use visual information to guide our arms toward objects of interest. Typically, these visually guided movements involve first focusing our gaze on the intended target and then reaching toward the direction of our gaze. The literature on eye-hand coordination provides a great deal of evidenc...

journal_title：Brain research

authors： Gorbet DJ,Sergio LE

更新日期：2009-08-11 00:00:00

abstract：:In the neonatal kitten, cuneate neurones activated by tactile stimulation of the forelimb foot pads are divisible into 3 functional classes each of which appears to receive its glabrous skin input selectively from a single class of tactile receptors. Their properties suggest that the functionally specific patterns of ...

journal_title：Brain research

authors： Ferrington DG,Rowe MJ

更新日期：1981-06-01 00:00:00

abstract：:Hypothalamic stimulation generally inhibits baroreflex-induced bradycardia. However, we have noted discrete areas of the rat hypothalamus which facilitate reflex bradycardia. The effects of hypothalamic stimulation on baroreflex-induced changes in heart rate were investigated in urethane-anesthetized rats (1.2 g/kg, i...

journal_title：Brain research

authors： Pardini BJ,Patel KP,Schmid PG,Lund DD

更新日期：1986-10-08 00:00:00

abstract：:In order to establish the cellular and subcellular localization of the chemokine protein, vascular endothelial growth factor (VEGF) or vascular permeability factor, in adult human retina, we employed immunocytochemistry with double immunolabeling, using a primary antibody to amino acids 1-10 of VEGF, together with ant...

journal_title：Brain research

authors： Famiglietti EV,Stopa EG,McGookin ED,Song P,LeBlanc V,Streeten BW

更新日期：2003-04-18 00:00:00

abstract：:The ability of membrane-associated peptidases from the brains of spontaneously hypertensive rats (SHRs) and normotensive Wistar-Kyoto (WKY) rats to metabolize iodinated angiotensin (125I-Ang II) and 125I-Ang III was compared. 125I-Ang II was metabolized to 125I-Ang III and other fragments exclusively by membrane-assoc...

journal_title：Brain research

authors： Cook VI,Wright JW,Wright SA,Harding JW

更新日期：1990-10-08 00:00:00

abstract：:Dapsone (4,4'-diaminodiphenylsulfone) is employed in the chemotherapy against leprosy. Dapsone also prevents neuronal damage induced by glutamate agonists. As glutamate excitotoxicity is implicated in the damage after ischemia, we tested the ability of dapsone to prevent ischemic injury in a model of permanent middle ...

journal_title：Brain research

authors： Ríos C,Nader-Kawachi J,Rodriguez-Payán AJ,Nava-Ruiz C

更新日期：2004-03-05 00:00:00

abstract：:Neuroglobin (Ngb) and Cytoglobin (Cygb) are new members of the globin family and display heterotopic expression patterns. To examine the effect of different hypoxia profiles on expression of Ngb and Cygb in rodent brain, rats were exposed to either sustained hypoxia (SH; 10% O(2)) or intermittent hypoxia (IH; 10% and ...

journal_title：Brain research

authors： Li RC,Lee SK,Pouranfar F,Brittian KR,Clair HB,Row BW,Wang Y,Gozal D

更新日期：2006-06-22 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH)-like immunoreactivity was examined in the rat olfactory bulb by an immunohistochemical method using antiserum against the tripeptide TRH. TRH-immunoreactive neurons and neuronal processes were localized in both main and accessory olfactory bulb, including the glomerular layer, exter...

journal_title：Brain research

authors： Tsuruo Y,Hökfelt T,Visser TJ

更新日期：1988-04-26 00:00:00

abstract：:Dysfunction in the hypothalamic GABAergic system has been implicated in panic syndrome in humans. Furthermore, several studies have implicated the hypothalamus in the elaboration of pain modulation. Panic-prone states are able to be experimentally induced in laboratory animals to study this phenomenon. The aim of the ...

journal_title：Brain research

authors： Freitas RL,Uribe-Mariño A,Castiblanco-Urbina MA,Elias-Filho DH,Coimbra NC

更新日期：2009-12-11 00:00:00

abstract：:We examined the involvement of tumor necrosis factor (TNF)-alpha on glutamate-induced cytotoxicity in a differentiated neuronal cell line. In this study, we used nerve growth factor (NGF)-differentiated PC12h cells. Glutamate cytotoxicity was assessed using the MTS and TUNEL assays. To detect TNF-alpha levels in cultu...

journal_title：Brain research

authors： Kogo J,Takeba Y,Kumai T,Kitaoka Y,Matsumoto N,Ueno S,Kobayashi S

更新日期：2006-11-29 00:00:00