NMDA receptors are not involved in the MK-801-induced increase of striatal dopamine release in rat: a microdialysis study.

abstract：:The neurobiology of social bonding, despite its relevance to human mental health, has been studied primarily in rodents. In this study we used position emission tomography (PET), registered with structural magnetic resonance imaging (MRI) to investigate central glucose uptake in 17 males of a monogamous primate specie...

journal_title：Brain research

authors： Bales KL,Mason WA,Catana C,Cherry SR,Mendoza SP

更新日期：2007-12-12 00:00:00

abstract：:Type 1 cannabinoid (CB1) receptors are expressed in high concentrations in the central nervous system, including the basal ganglia, and could have direct or indirect effects on motor behavior through modulation of dopaminergic, glutamatergic and GABA-ergic neurotransmission. Using the CB1 receptor radioligand [(18)F]M...

journal_title：Brain research

authors： Casteels C,Lauwers E,Baitar A,Bormans G,Baekelandt V,Van Laere K

更新日期：2010-02-26 00:00:00

abstract：:Picture-word interference is a widely employed paradigm to investigate lexical access in word production: Speakers name pictures while trying to ignore superimposed distractor words. The distractor can be congruent to the picture (pictured cat, word cat), categorically related (pictured cat, word dog), or unrelated (p...

journal_title：Brain research

authors： Piai V,Roelofs A,van der Meij R

更新日期：2012-04-23 00:00:00

abstract：:In the present study, we investigated the possibility that MK-801 (dizocilpine), a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, owes its potent neuroprotective properties to calcium channel blocking ability rather than to its NMDA receptor antagonism. Rat hippocampal slices were exposed to a long hy...

journal_title：Brain research

authors： Schurr A,Payne RS,Rigor BM

更新日期：1995-07-03 00:00:00

abstract：:The L-isomer of beta-N-methylamino-L-alanine (BMAA), present in free form in seed of Cycas circinalis, elicits in spinal cord cultures a pattern of acute postsynaptic neuronal vacuolation comparable to that induced by beta-N-oxalylamino-L-alanine (BOAA), an excitotoxic amino acid of greater potency isolated from seed ...

journal_title：Brain research

authors： Nunn PB,Seelig M,Zagoren JC,Spencer PS

更新日期：1987-05-05 00:00:00

abstract：:Despite insights into an increasingly significant role for delta opioid receptors in thermoregulation, it is unclear whether delta receptors located in the brain or periphery play the more critical role in body temperature regulation. Moreover, it is not entirely clear which delta receptor phenotype, delta1 or delta2,...

journal_title：Brain research

authors： Rawls SM,Hewson JM,Inan S,Cowan A

更新日期：2005-07-05 00:00:00

abstract：:In order to elucidate the functional role of nicotinic receptors in the hypothalamus, the drug-induced release of noradrenaline from hypothalamic synaptosomes was studied utilizing [3H]noradrenaline ([3H]NA). The release of [3H]NA from synaptosomes was significantly increased with an increase of the dose of nicotine, ...

journal_title：Brain research

authors： Yoshida K,Kato Y,Imura H

更新日期：1980-01-27 00:00:00

abstract：:Prefrontal impairments have been hypothesized to be most strongly associated with the cognitive and emotional dysfunction in depression. Recently, white matter microstructural abnormalities in prefrontal lobe have been reported in elderly patients with major depressive disorder (MDD) using diffusion tensor imaging (DT...

journal_title：Brain research

authors： Li L,Ma N,Li Z,Tan L,Liu J,Gong G,Shu N,He Z,Jiang T,Xu L

更新日期：2007-09-07 00:00:00

abstract：:Animal models of cerebral infarction are crucial to understanding the mechanisms of neuronal survival following ischemic brain injury and to the development of therapeutic interventions for victims of all types of stroke. Rodents have been used extensively in such research. One rodent model of stroke utilizes either p...

journal_title：Brain research

authors： Duckworth EA,Butler TL,De Mesquita D,Collier SN,Collier L,Pennypacker KR

更新日期：2005-04-25 00:00:00

abstract：:This work describes the change in an active electrogenesis of the command neurons responsible for defensive closure of a snail's pneumostome during elaborating, extinction and restoration of a classical conditioned defensive reflex to a tactile stimulus. Tactile stimulations applied to different parts of a snail's bod...

journal_title：Brain research

authors： Tsitolovsky LE,Babkina NV

更新日期：1992-11-06 00:00:00

abstract：:Clusters of carotid body (glomus) cells cultured from a few days to 3 weeks, maintained their morphological characteristics during this period. The resting potential (Em) and input resistance (Ro) did not change for 2 weeks but both declined afterwards. The intracellular pH (pHi) of glomus cells, measured with glass m...

journal_title：Brain research

authors： He SF,Wei JY,Eyzaguirre C

更新日期：1991-05-03 00:00:00

abstract：:The present study investigated the antidepressant potential of curcumin in olfactory bulbectomy and forced swimming test models of depression in male albino rats under chronic treatment. The experimental animals were divided into four groups, and curcumin was administered for 45 days. Our results showed that the curcu...

journal_title：Brain research

authors： Chang XR,Wang L,Li J,Wu DS

更新日期：2016-07-01 00:00:00

abstract：:We have explored the potential neuroprotective effect of local lentiviraly-mediated overexpression of nerve growth factor (NGF) on in vivo long-term potentiation (LTP) in the rat hippocampus under pathological conditions. The suspension of lentiviral particles was prepared using a genetic construct containing the huma...

journal_title：Brain research

authors： Uzakov SS,Ivanov AD,Salozhin SV,Markevich VA,Gulyaeva NV

更新日期：2015-10-22 00:00:00

abstract：:The effects of hypothermia on caspase-3 activation were investigated in the newborn rat brain after hypoxia-ischemia (HI). Intense caspase-3 activation was observed in the control brains after HI, but this activation was significantly reduced by postischemic hypothermia. These findings suggest that the inhibition of c...

journal_title：Brain research

authors： Fukuda H,Tomimatsu T,Watanabe N,Mu JW,Kohzuki M,Endo M,Fujii E,Kanzaki T,Murata Y

更新日期：2001-08-10 00:00:00

abstract：:Hippocampal CA1 pyramidal neurons undergo delayed neurodegeneration after transient forebrain ischemia, and the phenomenon is dependent upon hyperactivation of l-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) subtype of glutamate receptors, resulting in aberrant intracellular calcium influx. The GluR2 sub...

journal_title：Brain research

authors： Kaur J,Zhao Z,Geransar RM,Papadakis M,Buchan AM

更新日期：2006-02-23 00:00:00

abstract：:A substantial number of patients do not respond sufficiently to antidepressant drugs and are therefore often co-medicated with lithium as an augmentative strategy. Since lithium has been demonstrated to affect 5-HT neurotransmission, we examined the effect of acute and subchronic lithium on 5-HT levels after a challen...

journal_title：Brain research

authors： Wegener G,Linnet K,Rosenberg R,Mørk A

更新日期：2000-07-21 00:00:00

abstract：:Previous work has shown a relatively high turnover of adrenaline in the mediobasal hypothalamus during the critical period (15.00-17.00 h) of the proestrous rat. We now report that this high level of adrenergic activity can be detected in the median eminence (turnover rate 1.62 +/- 0.36 pg/micrograms protein/h) rather...

journal_title：Brain research

authors： Sheaves R,Warburton E,Laynes R,Mackinnon P

更新日期：1984-12-10 00:00:00

abstract：:Previous studies in piglets show that opioid-induced pial artery dilation was impaired following fluid percussion brain injury (FPI). This study was designed to determine the role of the newly described opioid nociceptin orphanin FQ (NOC/oFQ) in such impaired dilation to other opioids after FPI. CSF NOC/oFQ concentrat...

journal_title：Brain research

authors： Armstead WM

更新日期：2000-06-30 00:00:00

abstract：:The contribution of neurons in the nucleus medianus (NM) in mediating the drinking and pressor responses elicited by administration of angiotensin II (AII) either directly into the subfornical organ (SFO) or intravenously was investigated in conscious, unrestrained rats. Microinjection of AII into the SFO elicited a r...

journal_title：Brain research

authors： Gutman MB,Jones DL,Ciriello J

更新日期：1989-05-29 00:00:00

abstract：:Some kinds of nociception appear to be partially mediated by the release of substance P (SP) in the spinal cord dorsal horn from terminals of primary afferent nociceptors. Only some nociceptors contain and release SP however. Specifically, SP appears to be released by unmyelinated (C) nociceptive afferents when activa...

journal_title：Brain research

authors： Zachariou V,Goldstein BD,Yeomans DC

更新日期：1997-03-28 00:00:00

abstract：:PGP 9.5 is a new cytoplasmic neuron-specific protein structurally and immunologically distinct from neuron-specific enolase. A specific antiserum has now shown that this protein is widely distributed in vertebrate brains and is also present in cells of the human diffuse neuroendocrine system. PGP 9.5 appears to be old...

journal_title：Brain research

authors： Thompson RJ,Doran JF,Jackson P,Dhillon AP,Rode J

更新日期：1983-11-14 00:00:00

abstract：:The interpeduncular nucleus (IPN) was stimulated electrically while single-cell activity was recorded in the nucleus raphe magnus (NRM) of rats under pentobarbital anesthesia. Two classes of NRM cell were examined, those inhibited (off-cells) and those excited (on-cells) by noxious mechanical skin stimulation. Off-cel...

journal_title：Brain research

authors： Hentall ID,Budhrani VM

更新日期：1990-07-09 00:00:00

abstract：:The present study investigated the effect of dextromethorphan and 6,7-dinitroquinoxaline-2,3-dione (DNQX) pre-treatment on the development of cocaine- and lidocaine-induced seizures. The dopaminergic action of cocaine was also studied. The NMDA antagonist dextromethorphan and the non-NMDA (AMPA/kainate) antagonist DNQ...

journal_title：Brain research

authors： Barat SA,Abdel-Rahman MS

更新日期：1997-05-09 00:00:00

abstract：:A monoclonal antibody was made using the spleen cells of a mouse immunized with chick synaptic membranes and designated as mAb 1D12. It immunoprecipitated 25% of the omega-conotoxin binding protein but no dihydropyridine binding protein solubilized from chick brain membranes. By immunoblotting, a polypeptide of 58-kDa...

journal_title：Brain research

authors： Takahashi M,Arimatsu Y,Fujita S,Fujimoto Y,Kondo S,Hama T,Miyamoto E

更新日期：1991-06-14 00:00:00

abstract：:To determine the involvement of the hippocampal regions in a operant-type delayed alternation task of short delay or long delay, microinjections of muscimol into the hippocampus were used for temporal inactivation during the behavioral test in each rat. Dorsal hippocampal inactivation impaired the correct ratio of lon...

journal_title：Brain research

authors： Maruki K,Izaki Y,Hori K,Nomura M,Yamauchi T

更新日期：2001-03-23 00:00:00

abstract：:The patch-clamp technique was used to characterize the single channel ion currents in primary cultures of rat astrocytes. The most dominant channel type, which was found in over half of the inside-out membrane patches, was a potassium channel. The measured reversal potential was -67 mV, which is close to the calculate...

journal_title：Brain research

authors： Jalonen T,Holopainen I

更新日期：1989-04-10 00:00:00

abstract：:Deacetylation is a rapid clearance mechanism for ocular melatonin. We have studied the distribution of retinal melatonin deacetylase activity among vertebrate classes. Exogenous radiolabeled melatonin is metabolized by ocular tissue prepared from the amphibian Xenopus laevis, the reptile Anolis carolinensis, the teleo...

journal_title：Brain research

authors： Grace MS,Cahill GM,Besharse JC

更新日期：1991-09-13 00:00:00

abstract：:β-Amyloid peptide (Aβ) plays a central role in the pathogenesis of Alzheimer׳s disease, but in lower amounts it is found in normal brains where it participates in physiological processes and probably regulates synaptic plasticity. This study investigated the effects of physiologically relevant concentrations of Aβ (1 ...

journal_title：Brain research

authors： Bukanova JV,Sharonova IN,Skrebitsky VG

更新日期：2014-04-16 00:00:00

abstract：:How does attention interact with learning? Kruschke [Kruschke, J.K. (2001). Toward a unified Model of Attention in Associative Learning. J. Math. Psychol. 45, 812-863.] proposed a model (EXIT) that captures Mackintosh's [Mackintosh, N.J. (1975). A theory of attention: Variations in the associability of stimuli with re...

journal_title：Brain research

authors： Pauli WM,O'Reilly RC

更新日期：2008-04-02 00:00:00

abstract：:Agents such as 619C89 decrease extracellular glutamate concentrations by a primary action at voltage sensitive sodium channels, but NMDA antagonists also have been shown to decrease extracellular glutamate concentration after ischemia. To address the question as to whether 619C89's effect upon extracellular glutamate ...

journal_title：Brain research

authors： Chen J,Graham SH,Simon RP

更新日期：1995-11-13 00:00:00