Abstract：
:The neurobiology of social bonding, despite its relevance to human mental health, has been studied primarily in rodents. In this study we used position emission tomography (PET), registered with structural magnetic resonance imaging (MRI) to investigate central glucose uptake in 17 males of a monogamous primate species, the titi monkey (Callicebus cupreus). Twelve pair-bonded males (including six with a lesion of the prefrontal cortex) and five lone males were scanned. The five lone males were re-scanned 48 h after pairing with a female. Significant differences in glucose uptake were found between males in long-term pair-bonds and lone males in areas including the nucleus accumbens, ventral pallidum, medial preoptic area, medial amygdala, and the supraoptic nucleus of the hypothalamus. In paired before and after comparisons, males showed significant changes following pairing in the right nucleus accumbens and ventral pallidum but not in other areas. Lesioned males showed significantly higher uptake in the posterior cingulate cortex than all other males. These results indicate some basic similarities between rodents and primates in the formation and maintenance of selective social bonds, but emphasize the importance of studying long-term maintenance in addition to short-term formation of social bonds.
journal_name
Brain Resjournal_title
Brain researchauthors
Bales KL,Mason WA,Catana C,Cherry SR,Mendoza SPdoi
10.1016/j.brainres.2007.09.087subject
Has Abstractpub_date
2007-12-12 00:00:00pages
245-53eissn
0006-8993issn
1872-6240pii
S0006-8993(07)02331-1journal_volume
1184pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:Pretreatment with recombinant human interleukin-1 alpha (rhIL-1 alpha) 20 h before irradiation attenuates radiation-induced hyperthermia. Experiments were conducted to determine the role of antioxidant enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GSHPx) in rhIL-1 alpha-induced attenuation of ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91576-e
更新日期：1993-03-19 00:00:00
abstract：:In the dorsal horn of barbiturate-anaesthetized cats evidence was obtained for a different distribution of enkephalin-preferring and morphine-preferring receptors. When ejected electrophoretically from micropipettes, morphine reduced the nociceptive responses of neurones of laminae IV and V when administered in the su...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)91002-7
更新日期：1981-12-21 00:00:00
abstract：:In a single 10-s training trial, hatchling chicks were conditioned to suppress their spontaneous peck response to a small spherical target by coating it with an aversive liquid. A 24-h test trial employing a dry target demonstrated a robust memory for the training manifested in passive avoidance behavior. Leupeptin, a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(87)90763-3
更新日期：1987-03-17 00:00:00
abstract：:Maternal melatonin readily crosses the placenta to provide the fetus with time-of-day and day length information. To determine if melatonin could have a broader role during development than is currently recognized, melatonin receptor expression was examined in somatic sites during Siberian hamster embryogenesis. Using...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(91)91424-y
更新日期：1991-12-24 00:00:00
abstract：:The expression of adenylyl cyclase (AC) isoforms in the adult rat vestibular periphery was investigated using reverse transcription polymerase chain reaction (RT-PCR). AC II, IV and V mRNAs were expressed in both Scarpa's ganglion and vestibular end organs. In addition, in the vestibular end organs, an AC mRNA not pre...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02007-2
更新日期：2000-03-24 00:00:00
abstract：:In vivo proton magnetic resonance spectroscopy was used to investigate intracerebral phenylalanine (Phe) concentrations in nine patients with classical phenylketonuria (PKU). The study included serial examinations (n = 31; plasma Phe levels: 0.47-2.24 mmol/l) of patients either receiving a Phe-restricted diet (200 mg ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)01054-8
更新日期：1997-12-19 00:00:00
abstract：:A study was undertaken of the possible relationship of the binding affinity of a series of anticholinergic psychotomimetic drugs to their psychopharmacological and anticholinergic effects. Binding was measured to brain homogenates and nerve endings using [3H]quinuclidinyl benzilate (QB), a highly potent psychotomimeti...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(77)90889-7
更新日期：1977-03-25 00:00:00
abstract：:The carotid body of the mouse is ideally suited for in vitro photometric and fluorometric studies using transillumination. It is small, thin and translucent. Photometric recordings were made by using a dual wavelength method. Wavelengths of 550 nm (maximal absorbance, MA) and 540 nm (isosbestic point, IP) were employe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90019-8
更新日期：1985-03-18 00:00:00
abstract：:Nitric oxide synthase (NOS) activity was examined in forebrain, cerebellum and optic lobes of adult domestic fowl, having a hereditary primary generalized convulsive disorder. NOS was approximately 2-fold higher in only the forebrain of adult epileptic fowl compared to non-epileptic (carrier) hatchmates. A significant...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00595-1
更新日期：1996-10-07 00:00:00
abstract：:Mammalian transglutaminases (TGs) catalyze the irreversible post-translational modifications of proteins, the most prominent of which is the calcium-dependent formation of covalent acyl transfers between the γ-carboxamide group of glutamine and the ε-amino-group of lysine (GGEL-linkage). In the central nervous system,...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2015.11.027
更新日期：2016-01-15 00:00:00
abstract：:Our previous studies demonstrated that only a few days of housing in an enriched environment increases response strength and paired-pulse depression in the auditory cortex of awake and anesthetized rats [Engineer, N.D., Percaccio, C.R., Pandya, P.K., Moucha, R., Rathbun, D.L., Kilgard, M.P., 2004. Environmental enrich...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.07.062
更新日期：2007-10-12 00:00:00
abstract：:Calcium accumulation and neuronal injury of rat cortical cell cultures in vitro were examined following oxygen deprivation under conditions of normal and low glucose. 45Ca2+ uptake and lactate dehydrogenase (LDH) release, measured at 12 and 24 h after oxygen deprivation, were significantly elevated in cultures exposed...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91527-y
更新日期：1993-04-02 00:00:00
abstract：:Both enkephalin and 5-hydroxytryptamine (5-HT) have been implicated in neural mechanisms underlying the central control of respiration. In view of the role of the nuclei tractus solitarii (NTS) in respiratory regulation, we carried out a study in artificially ventilated, chloralose-anaesthetized cats of the effects of...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91515-x
更新日期：1985-02-18 00:00:00
abstract：:Transient ischemic attack (TIA) has received only little attention in the experimental research field. Recently, we introduced a TIA model for mice, and here we set similar principles for simulating this human condition in Wistar rats. In the model: 1) transient nature of the event is ensured, and 2) 24h after the eve...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2017.03.010
更新日期：2017-05-15 00:00:00
abstract：:In behaving cats, a cholinergic agonist, carbachol, or Ringer's solution were infused into the pontine reticular formation (PRF). Extracellular microelectrode recordings were obtained from single neurons located 1-4 mm from the infusion site. Sleep polygraphic variables were also recorded. Carbachol microinfusions int...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90137-x
更新日期：1986-10-29 00:00:00
abstract：:Niemann-Pick Type C (NPC) disease is an autosomal recessive neurodegenerative disorder with abnormal lipid storage as the major cellular pathologic hallmark. Genetic analyses have identified mutations in NPC1 gene in the great majority of cases, while mutations in NPC2 account for the remainders. Yet little is known r...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.02.019
更新日期：2010-04-14 00:00:00
abstract：:Mice lacking the GABA(A) receptor beta(3) subunit exhibit a profound disruption in thalamic circuitry. We have studied sleep in these mice under baseline conditions and following treatment with the benzodiazepine midazolam. Under baseline conditions, NREM sleep time did not differ between beta(3) subunit knockout mice...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03467-4
更新日期：2002-11-15 00:00:00
abstract：:Glial cell line derived neurotrophic factor (GDNF) is a potent survival factor for several types of neurons. GDNF binds with high affinity to GDNF-family receptor alpha-1 (GFR alpha-1). This receptor is expressed in different areas of the brain, including the hippocampus and dentate gyrus. By using in situ hybridizati...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02682-2
更新日期：2000-09-22 00:00:00
abstract：:The autoradiographic [14C]2-deoxyglucose (2-DG) method was used to map ascending pathways which are influenced by arousing electrical stimulation of the midbrain reticular formation (RET) in alert rats. The major finding was that RET stimulation produces selective patterns of metabolic activation and suppression in di...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)91190-4
更新日期：1985-09-30 00:00:00
abstract：:Transiently increased immunoreactivity of the calcium binding protein S-100beta was demonstrated in spinal ganglion nerve cells after sciatic nerve transection. Neuropeptide Y (NPY), normally not seen in these nerve cells, appeared concomitantly. The transiently elevated co-expression of S-100beta and NPY is proposed ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)01425-x
更新日期：1998-03-02 00:00:00
abstract：:Previous studies on the processing of fractions and proportions focused mainly on the processing of their overall magnitude information in the intraparietal sulcus (IPS). However, the IPS is also associated with domain-general cognitive functions beyond processing overall magnitude, which may nevertheless be involved ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2019.02.029
更新日期：2019-07-01 00:00:00
abstract：:We have previously reported that intracerebroventricular (i.c.v.) injection of either a PKC or PKA inhibitor completely reversed the expression of 5- to 8-fold morphine antinociceptive tolerance. We developed a model of 45-fold morphine tolerance that included a 75-mg morphine pellet and twice daily morphine injection...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(03)03170-6
更新日期：2003-09-19 00:00:00
abstract：:Binge-like ethanol treatment of septal neurons blunts GABAAR-mediated miniature postsynaptic currents (mPSCs), suggesting it arrests synaptic development. Ethanol may disrupt postsynaptic maturation by blunting feedback signaling through immature GABAARs. Here, the impact of ethanol on the sensitivity of mPSCs to zolp...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.03.023
更新日期：2006-05-17 00:00:00
abstract：:The extraction and utilization of sound level changes in acoustic-autonomic reflex systems were studied on a vasoconstriction response in the tail of nonanesthetized rats. The vasoconstriction was found to depend on sound level and changes of level in the following ways. (a) It increased as a linear function of sound ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)90555-7
更新日期：1980-04-21 00:00:00
abstract：:The present work shows the existence of adenosine-dependent cyclic adenosine monophosphate (AMP) accumulation in the chick optic tectum. When tecta from 18-day-old embryos were incubated with the phosphodiesterase inhibitor IBMX and RO 20-1724, the cyclic AMP level increased from 39.2 to 73.3 and 285.5 pmol/mg protein...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(87)90016-2
更新日期：1987-09-01 00:00:00
abstract：:Although there are indications of growth in the size and myelination of the rat corpus callosum during adulthood, it is not known how long this growth continues. In addition, the potential for age-related changes in these measures to affect the sex differences seen in adulthood has not been examined. Here the size of ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.01.043
更新日期：2007-04-20 00:00:00
abstract：:The synaptic regulatory mechanism of resting membrane potential of layer III and V pyramidal neurons was analyzed intracellularly in the slice preparation of cat sensorimotor cortex. During the tetanic stimulation of white matter, subthreshold membrane depolarization was induced, and after that, a slowly developing hy...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02353-2
更新日期：2000-06-30 00:00:00
abstract：:Based on the fact that several recent reports have indicated that non-immunosuppressive immunophilin ligands (IPLs) can activate neurite outgrowth or nerve regeneration, we investigated the neurotrophic factor-activating abilities of IPLs in vivo in order to clarify the molecular basis of neurotrophic-like activity. B...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(03)02434-x
更新日期：2003-04-25 00:00:00
abstract：:In an effort to further characterize the proteins of the auditory nerve, the effects of hair cell loss on rapidly transported proteins of the auditory nerve were studied. The effects were studied in the waltzing guinea pig, a genetically deaf animal which displays an age-dependent loss of sensory cells, and in normal ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90693-x
更新日期：1982-12-16 00:00:00
abstract：:The distribution and density of noradrenergic (NA) and serotonergic (5-HT) varicosities in the superior olive (SO) and periolivary region (PO) and their relationship to olivocochlear neurons was studied. Antibodies against 5-HT and the NA precursor enzyme dopamine beta-hydroxylase were utilized to examine the density ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(99)01541-3
更新日期：1999-07-31 00:00:00
