Response of rat brain to calcitonin alteration.

abstract：:Recent reports have identified discrepancies between the anatomical distribution of transmitters and their receptors, a phenomenon known as transmitter-receptor mismatch. However, quantitative determinations of transmitter activity and receptor density in individual brain regions have not been conducted in parallel. W...

journal_title：Brain research

authors： Ernsberger P,Arneric SP,Arango V,Reis DJ

更新日期：1988-06-14 00:00:00

abstract：:Approximately 40-60% of BXSB mice have ectopic cell clusters in layer 1 of neocortex. Prior studies have shown distinct behavioral differences between those with ectopias and their non-ectopic littermates. In this study, female BXSB mice were reared after weaning in either enriched environments or standard cages. Foll...

journal_title：Brain research

authors： Boehm GW,Sherman GF,Hoplight BJ 2nd,Hyde LA,Waters NS,Bradway DM,Galaburda AM,Denenberg VH

更新日期：1996-07-08 00:00:00

abstract：:The feedback effect of activity of area 21a on orientation maps of areas 17 and 18 was investigated in cats using intrinsic signal optical imaging. A spatial frequency-dependent decrease in response amplitude of orientation maps to grating stimuli was observed in areas 17 and 18 when area 21a was inactivated by local ...

journal_title：Brain research

authors： Huang L,Chen X,Shou T

更新日期：2004-02-20 00:00:00

abstract：:This study examined the involvement of N-methyl-D-aspartate receptors (NMDARs) in experience-dependent synaptic plasticity. Rats chronically received an NMDA receptor antagonist (AP5) or saline (SAL) and were exposed to individual cages (IC) or environmental enrichment (EC). AP5 impaired measures of hippocampal-depend...

journal_title：Brain research

authors： Foster TC,Fugger HN,Cunningham SG

更新日期：2000-07-14 00:00:00

abstract：:Cytosolic phospholipase A2 (cPLA2) catalyzes the selective release of arachidonic acid from the sn-2 position of membrane phospholipids and has been suggested as an effector in the receptor-mediated release of arachidonic acid in signal transduction. The potential role of cPLA2 as an effector in muscarinic acetylcholi...

journal_title：Brain research

authors： Lautens LL,Chiou XG,Sharp JD,Young WS 3rd,Sprague DL,Ross LS,Felder CC

更新日期：1998-10-26 00:00:00

abstract：:Some occluded arteries of acute ischemic stroke (AIS) patients are not recanalized, even if thrombolytic therapy is performed. Considering such clinical settings, we examined the potential cerebroprotective efficacy of TAK-937, a novel cannabinoid receptor agonist, in young adult and aged rats with a permanent middle ...

journal_title：Brain research

authors： Murakami K,Suzuki M,Suzuki N,Hamajo K,Tsukamoto T,Shimojo M

更新日期：2013-08-14 00:00:00

abstract：:In scopolamine-treated (5.0 mg/kg, s.c.) rats hippocampal rhythmical slow activity (RSA) and neocortical low voltage fast activity (LVFA) occur only in close correlation with head movements, spontaneous changes in posture, or locomotion (Type I behavior). Previous work indicates that such scopolamine-resistant RSA and...

journal_title：Brain research

authors： Watson NV,Hargreaves EL,Penava D,Eckel LA,Vanderwolf CH

更新日期：1992-11-27 00:00:00

abstract：:Neuropathic pain remains a major complication of various forms of injury to peripheral nerves in humans. Recently, 2 models of peripheral mononeuropathy in the rat have been described which closely resemble the human condition. Bennett and Xie3 described one model induced by the placement of 4 loose ligatures around t...

journal_title：Brain research

authors： Dougherty PM,Garrison CJ,Carlton SM

更新日期：1992-01-20 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) is a well neurotrophic factor with neuroprotective potentials for various diseases in the central nervous system. However several previous studies demonstrated that BDNF might deteriorate symptoms for epilepsy model of animals by progression of abnormal neurogenesis. We hypothe...

journal_title：Brain research

authors： Kuramoto S,Yasuhara T,Agari T,Kondo A,Jing M,Kikuchi Y,Shinko A,Wakamori T,Kameda M,Wang F,Kin K,Edahiro S,Miyoshi Y,Date I

更新日期：2011-01-12 00:00:00

abstract：:Mice lacking the GABA(A) receptor beta(3) subunit exhibit a profound disruption in thalamic circuitry. We have studied sleep in these mice under baseline conditions and following treatment with the benzodiazepine midazolam. Under baseline conditions, NREM sleep time did not differ between beta(3) subunit knockout mice...

journal_title：Brain research

authors： Wisor JP,DeLorey TM,Homanics GE,Edgar DM

更新日期：2002-11-15 00:00:00

abstract：:The roles of noradrenergic and serotonergic projections to the hippocampus were investigated with respect to their involvement in the intracranial self-stimulation of this structure. In the first study, 6-hydroxydopamine-induced lesions of the dorsal tegmental noradrenergic bundle, which depleted hippocampal NE by 97%...

journal_title：Brain research

authors： van der Kooy D,Fibiger HC,Phillips AG

更新日期：1977-11-04 00:00:00

abstract：:Extracellular recording was used to investigate spontaneously active neurons in all four major nuclei of the rat vestibular nuclear complex (VNC) in brainstem slices. The density of spontaneously active neurons was highest in the medial vestibular nucleus (MVN), slightly lower in the superior (SuVN) and spinal (SpVN) ...

journal_title：Brain research

authors： Sun Y,Waller HJ,Godfrey DA,Rubin AM

更新日期：2002-04-26 00:00:00

abstract：:The levels of N-acetyl-aspartate (NAA) and N-acetyl-aspartyl-glutamate (NAAG) were measured in several regions and in whole brain of rats from 15 days of gestation (DG) to adulthood by means of an isocratic HPLC method. The levels of NAAG in whole brain increased 3-fold between 15 DG and birth, which was 90% of the ad...

journal_title：Brain research

authors： Koller KJ,Coyle JT

更新日期：1984-07-01 00:00:00

abstract：:Morphine is one of the most potent analgesics used in medicine and it's long-term use is associated with the risk of the state of dependence. The cessation of chronic morphine administration leads to withdrawal signs which are associated with neurotransmitter dysregulations within mesolimbic system. Adenosine 5'-triph...

journal_title：Brain research

authors： Metryka E,Gutowska I,Kupnicka P,Tarnowski M,Tkacz M,Listos J,Talarek S,Barczak K,Chlubek D,Baranowska-Bosiacka I

更新日期：2019-09-15 00:00:00

abstract：:During early postnatal development in reeler mutant mice, lectin binding delineates prospective abnormal barrels as they will appear in the adult mutant somatosensory cortex. Glial fibers also may be more condensed within fascicles in developing reeler barrels. These fibers also appear to be misaligned, coursing predo...

journal_title：Brain research

authors： O'Brien TF,Steindler DA,Cooper NG

更新日期：1987-04-01 00:00:00

abstract：:Diabetic retinopathy is the leading cause of acquired blindness in working-age individuals. Recent work has revealed that neurodegeneration occurs earlier than vascular insult and that distal optic nerve damage precedes retinal degeneration and vascular insult. Since we have shown that optic nerve degeneration is redu...

journal_title：Brain research

authors： Mendonça HR,Carvalho JNA,Abreu CA,Mariano de Souza Aguiar Dos Santos D,Carvalho JR,Marques SA,da Costa Calaza K,Martinez AMB

更新日期：2018-12-01 00:00:00

abstract：:Symbolic visual cues indicating the location of an upcoming target are believed to invoke endogenous shifts of attention to cued locations. In the present study, we investigated how visual attention is shifted during such cuing paradigms by recording event-related potentials (ERPs). We focused on a component known to ...

journal_title：Brain research

authors： Woodman GF,Arita JT,Luck SJ

更新日期：2009-11-10 00:00:00

abstract：:We used double staining immunocytochemical techniques to determine whether nitric oxide (NO) and Fos immunoreactivity induced by noxious visceral stimulation were colocalized in the neurons of the supraspinal areas. We observed a considerable increase in Fos-positive neurons in many brain areas after noxious stimulati...

journal_title：Brain research

authors： Rodella L,Rezzani R,Agostini C,Bianchi R

更新日期：1999-07-10 00:00:00

abstract：:Dissociated 4-day (stage 23) chick embryo lumbar cord cells were cultured at low or high cell densities for 1 or 5 days in the presence or absence of added spinal neuronotrophic factor (supplied as RN22 Schwannoma conditioned medium, RCM). In low density, 1-day cultures neuronal survival was dependent on added RCM whe...

journal_title：Brain research

authors： Manthorpe M,Luyten W,Longo FM,Varon S

更新日期：1983-05-09 00:00:00

abstract：:Opioid antagonists block the positive hedonic response to food taste and are potent inhibitors of palatability-driven feeding. However, the specific brain regions within which opioid peptide secretion contributes to the maintenance of palatability-driven feeding have not been clearly established. In the present study,...

journal_title：Brain research

authors： Park TH,Carr KD

更新日期：1998-09-14 00:00:00

abstract：:EEG power spectra exhibit site-specific and state-related differences in specific frequency bands. In the present study we investigated the effect of total sleep deprivation on sleep EEG topography. Eight healthy, young, right-handed subjects were recorded during baseline sleep and recovery sleep after sleep deprivati...

journal_title：Brain research

authors： Achermann P,Finelli LA,Borbély AA

更新日期：2001-09-21 00:00:00

abstract：:Auditory transients (such as sound onset or a frequency transition within a continuous sound) are assumed to parse the auditory input into smaller units enabling the formation of unitary sound representations separately for each segment. This was discovered by using the mismatch negativity (MMN) component of the event...

journal_title：Brain research

authors： Weise A,Bendixen A,Müller D,Schröger E

更新日期：2012-06-29 00:00:00

abstract：:We have examined the influence of reducing conditions on the activity of group-I or -II metabotropic glutamate receptors. In cultured cerebellar granule cells or in hippocampal slices, the reducing agent dithiothreitol (DTT) inhibited the stimulation of polyphosphoinositide (PPI) hydrolysis elicited by group-I mGlu re...

journal_title：Brain research

authors： Copani A,Romano C,Di Giorgi Gerevini V,Nicosia A,Casabona G,Storto M,Mutel V,Nicoletti F

更新日期：2000-06-09 00:00:00

abstract：:This study presents a three-dimensional analysis of pallido-thalamic axons and axonal endings in the monkey (Macaca mulatta and M. irus). Injections of the anterograde tracer biocytin were made in the dorsal, associative region of the medial pallidum. Numerous axonal endings were observed within the pallidal territory...

journal_title：Brain research

authors： Arecchi-Bouchhioua P,Yelnik J,François C,Percheron G,Tandé D

更新日期：1997-04-18 00:00:00

abstract：:In larval lamprey 4 weeks after a spinal transection locomotor patterns were usually complete along the body in whole animals. In in vitro preparations locomotor activity was restricted to a few millimeters below the transection. Retrograde labeling indicated that descending axons from a few brainstem neurons had grow...

journal_title：Brain research

authors： Davis GR Jr,McClellan AD

更新日期：1993-01-29 00:00:00

abstract：:Intracerebral hemorrhage (ICH) is a devastating stroke often modelled in rats. Isoflurane anesthetic, commonly used in preclinical research, affects general physiology (e.g., blood pressure) and electrophysiology (e.g., burst suppression) in many ways. These physiological changes may detract from the clinical relevanc...

journal_title：Brain research

authors： Wilkinson CM,Kalisvaart ACJ,Kung TFC,Maisey DR,Klahr AC,Dickson CT,Colbourne F

更新日期：2020-02-01 00:00:00

abstract：:Mice with reduced expression of the NR1 subunit of the NMDA receptor (NR1 hypomorphic mice) display altered behavioral phenotypes that may relate to behavioral characteristics of schizophrenia. Altered phenotypes in the NR1 hypomorphs include marked deficits in species-typical behavioral interactions in tests of socia...

journal_title：Brain research

authors： Duncan GE,Inada K,Farrington JS,Koller BH,Moy SS

更新日期：2009-04-10 00:00:00

abstract：:Stroke-prone spontaneously hypertensive rats (SHRSP) are a well-characterized, genetic model for stroke. We showed earlier that the structure and function of the tight junctions in SHRSP blood-brain barrier endothelial cells is disturbed prior to stroke. To investigate the molecular events leading to endothelial dysfu...

journal_title：Brain research

authors： Kirsch T,Wellner M,Luft FC,Haller H,Lippoldt A

更新日期：2001-08-10 00:00:00

abstract：:The growth inhibitory factor (GIF) is a new metallothionein (MT)-like protein that is downregulated in Alzheimer's disease (AD) brain. The biological function of GIF has not been fully clarified yet. We have raised an antibody to the synthetic polypeptide that is specific for rat GIF. The purified antibody reacted to ...

journal_title：Brain research

authors： Hozumi I,Inuzuka T,Hiraiwa M,Uchida Y,Anezaki T,Ishiguro H,Kobayashi H,Uda Y,Miyatake T,Tsuji S

更新日期：1995-08-07 00:00:00

abstract：:Evidence exists that repeated injections of melatonin in rather large doses inhibit sexual performance in male rats. In contrast, systemic injection of small doses of this hormone stimulates sexual activity of normal male rats. In these experiments, systemic acute administration of melatonin in small doses (10-100 mic...

journal_title：Brain research

authors： Drago F,Busa' L

更新日期：2000-09-29 00:00:00