Abstract：
:The reactivity of dopaminergic (DA) terminals in the nucleus accumbens was investigated in male rats submitted to tail-pinch or various social interactions. The DA activity was assessed by measurement of the presynaptic metabolite 3,4-dihydroxyphenylacetic acid (DOPAC) by using differential pulse voltammetry in free moving preparations. Tail-pinch lasting 5 min or 10 min was followed by increases in DA activity of 25% and 35%, respectively. Three types of social interaction were used: interaction with an aggressive male congener, interaction with a non-aggressive male congener or interaction with a female congener. The greatest increase in dopaminergic activity (40%) was observed after the aggressive interaction. The reactivity of the DA neurons within the nucleus accumbens is, therefore, dependent on the characteristics of the behavioral situation.
journal_name
Brain Resjournal_title
Brain researchauthors
Louilot A,Le Moal M,Simon Hdoi
10.1016/0006-8993(86)90646-3subject
Has Abstractpub_date
1986-11-12 00:00:00pages
395-400issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(86)90646-3journal_volume
397pub_type
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