Enhancement of current induced by superfusion of GABA in locus coeruleus neurons by pentobarbital, but not ethanol.

abstract：:Acute estradiol (E2) can potentiate the excitatory responses of hypothalamic ventromedial nucleus (VMN) neurons to neurotransmitters. To investigate the mechanism(s) underlying the potentiation, the whole-cell patch voltage clamp technique was used to study VMN neurons in hypothalamic slices prepared from female juven...

journal_title：Brain research

authors： Kow LM,Devidze N,Pataky S,Shibuya I,Pfaff DW

更新日期：2006-10-20 00:00:00

abstract：:We have previously demonstrated that NMDA receptor-mediated extracellular adenosine accumulation in neuronal cultures is receptor-mediated and requires calcium influx. Because protein kinase C (PKC) is a calcium-dependent enzyme, we hypothesized that activation of PKC might be involved in NMDA-mediated adenosine accum...

journal_title：Brain research

authors： Lu Y,Rosenberg PA

更新日期：2007-06-25 00:00:00

abstract：:"Dystrophic' mice of the 129/ReJ-Dy strain have a genetic defect affecting Schwann cell proliferation. Spinal nerve roots of these animals contain myelinated and unmyelinated axons in addition to groups of large "amyelinated' axons. In affected regions of the spinal roots, myelinated axons are missing their myelin she...

journal_title：Brain research

authors： Wiley-Livingston CA,Ellisman MH

更新日期：1981-11-09 00:00:00

abstract：:The kindling process represents a progressively augmenting electrical and behavioral response to brain stimulation, that has been proposed as a model for the development of epileptogenesis. The first experiment examined the effects of hypophysectomy on the kindling process. The effects of hypophysectomy were found to ...

journal_title：Brain research

authors： Rose RP,Morell F,Hoeppner TJ

更新日期：1979-06-22 00:00:00

abstract：:Chick embryos ranging in age from 4.0 to 18 days of incubation and 1-2-day-old hatchlings received injections of HRP solutions directly into the leg musculature. After survival periods of from 5 to 25 h motoneurons and cells in the spinal sensory ganglia were found to be stained with the HRP reaction product. It was f...

journal_title：Brain research

authors： Oppenheim RW,Heaton MB

更新日期：1975-11-14 00:00:00

abstract：:We examined the brain uptake of prostaglandin D2 after its i.v. administration to mice. The determination of this prostaglandin in tissues was performed by a sensitive and rapid radioimmunoassay after purification of the prostaglandin by high-performance liquid chromatography. When 1.0 mg/kg of prostaglandin D2 was in...

journal_title：Brain research

authors： Suzuki F,Hayashi H,Hayaishi O

更新日期：1986-10-22 00:00:00

abstract：:In monkeys (Macaca fuscata and mulatta), horseradish peroxidase (HRP) was injected in the cerebral cortices, areas 4 (medial and lateral parts), 5, 6 and 9 (a part just rostral to area 6), in which stimulation of cerebellar nuclei was known to elicit superficial or deep thalamocortical responses. Retrogradely labelled...

journal_title：Brain research

authors： Miyata M,Sasaki K

更新日期：1983-09-12 00:00:00

abstract：:In order to establish possible stimulatory effects of increasing plasma concentrations of substance P (SP) on the arginine vasopressin (AVP) and/or oxytocin (OT) secretion, successively increasing doses of SP(0.5, 1 and 1.5 pmol/kg-1/min-1; each dose for 20 min) were infused in 7 normal men. Plasma AVP and OT levels w...

journal_title：Brain research

authors： Chiodera P,Coiro V

更新日期：1992-01-08 00:00:00

abstract：:Injections of HRP throughout the upper tectal strata led in 4 cases to the appearance of retrogradely labeled neurons within n.isthmi ventralis, contralateral to the experimental side. An additional case proved that this projection courses through the ventral supraoptic commissure. This is the first description of a c...

journal_title：Brain research

authors： Martínez S,Puelles L

更新日期：1989-02-27 00:00:00

abstract：:Histamine is one of the neurotransmitters suppressing appetite, but the interactions of histaminergic neurons with other neurons in satiety centers have not been clarified. Noradrenaline in the para-ventricular nucleus (PVN) has been shown to stimulate feeding. This study was designed to determine whether histamine mo...

journal_title：Brain research

authors： Kurose Y,Terashima Y

更新日期：1999-05-15 00:00:00

abstract：:Microinjection of bicuculline (Bic) into the unilateral putamen (Put) of the cat resulted in periodic occurrence of contralateral movement of the head (dystonia). Corresponding to this dystonic movement, repetitive spikes of the field potential occurring in the Put of the injected side and strong inhibition of the ext...

journal_title：Brain research

authors： Yamada H,Fujimoto K,Yoshida M

更新日期：1995-04-24 00:00:00

abstract：:Male guinea pigs were given 3 tests for sexual behavior. Animals that never ejaculated were classified as low activity (LA), animals that ejaculated on one test were classified as medium activity (MA), and animals that ejaculated on two or more tests were classified as high activity (HA). Subsequently, animals from ea...

journal_title：Brain research

authors： Harding CF,Feder HH

更新日期：1976-03-19 00:00:00

abstract：:The effects of oral administration of the neuroleptic, haloperidol, on regional brain concentrations of cholecystokinin (CCK) and neurotensin were examined in the rat. Both short-term (3 weeks) and long-term (8 months) haloperidol administration increased the concentration of CCK in the substantia nigra. While short-t...

journal_title：Brain research

authors： Radke JM,MacLennan AJ,Beinfeld MC,Bissette G,Nemeroff CB,Vincent SR,Fibiger HC

更新日期：1989-02-20 00:00:00

abstract：:The impact of hyperglycemia after traumatic brain injury (TBI), and even the administration of glucose-containing solutions to head injured patients, remains controversial. In the current study adult male Sprague-Dawley rats were tested on behavioral tasks and then underwent surgery to induce sham injury or unilateral...

journal_title：Brain research

authors： Shijo K,Ghavim S,Harris NG,Hovda DA,Sutton RL

更新日期：2015-07-21 00:00:00

abstract：:We examined the effect of prostaglandin (PG)E2 on the sleep-wake activity and on body temperature by microinjecting PGE2 into the preoptic area of rats that had been chronically implanted with guide cannulae and electrodes for the recordings of electroencephalogram and electromyogram. PGE2 at doses of 2.5 X 10(-13), 2...

journal_title：Brain research

authors： Matsumura H,Goh Y,Ueno R,Sakai T,Hayaishi O

更新日期：1988-03-22 00:00:00

abstract：:The present study was undertaken to investigate in rats the role of the noradrenergic innervation of the hippocampus in the reversal by antidepressant drugs of escape failures caused by previous exposure to inescapable shocks (learned helplessness design). Rats were either sham-operated or given a bilateral infusion o...

journal_title：Brain research

authors： Soubrie P,Martin P,el Mestikawy S,Hamon M

更新日期：1987-12-29 00:00:00

abstract：:A subset of olfactory receptor neurons of the Caribbean spiny lobster Panulirus argus possesses receptors for L-glutamate that can mediate both excitatory and inhibitory responses (P.C. Daniel, M.F. Burgess, C.D. Derby, Responses of olfactory receptor neurons in the spiny lobster to binary mixtures are predictable usi...

journal_title：Brain research

authors： Burgess MF,Derby CD

更新日期：1997-10-17 00:00:00

abstract：:Cells in layers II-III or VI were activated by microdrop application of acetylcholine (ACh), while monitoring the intracellular response of layer V pyramidal cells. This enabled the tracing of functional connections between the cells of layers II-III or VI with those of layer V. ACh activation of layer II-III or VI ce...

journal_title：Brain research

authors： Kenan-Vaknin G,Malach R,Segal M

更新日期：1992-03-06 00:00:00

abstract：:Noxious stimulation of the leg increases hind limb blood flow (HBF) to the ipsilateral side and decreases to the contralateral in rat. Whether or not this asymmetrical response is due to direct control by sympathetic terminals or mediated by other factors such as local metabolism and hormones remains unclear. The aim ...

journal_title：Brain research

authors： Korim WS,McMullan S,Cravo SL,Pilowsky PM

更新日期：2011-05-19 00:00:00

abstract：:Available studies indicate that the adrenergic stimulation of pineal cyclic GMP production involves stimulation of guanylyl cyclase activity by nitric oxide (NO) derived from arginine. This line of investigation was extended in the present study. Using a highly sensitive microassay, it was found that pineal NO synthas...

journal_title：Brain research

authors： Lin AM,Schaad NC,Schulz PE,Coon SL,Klein DC

更新日期：1994-07-18 00:00:00

abstract：:To clarify the effects of arachidonic acid (AA) and its metabolites on desensitization of nicotinic acetylcholine (ACh) receptor channel in mouse skeletal muscle cells, we investigated the time-dependent decrease in the channel opening frequency of ACh (1 microM)-activated channel currents by the cell-attached patch c...

journal_title：Brain research

authors： Nojima H,Sasaki T,Kimura I

更新日期：2000-01-03 00:00:00

abstract：:We used double-barreled pH-sensitive microelectrodes to study the mechanisms by which the intracellular pH is regulated in the connective glial cells of the medicinal leech. The experiments indicate that a Cl(-)- and HCO3(-)-dependent mechanism mediates some recovery from intracellular alkalosis even in the absence of...

journal_title：Brain research

authors： Szatkowski MS,Schlue WR

更新日期：1994-11-28 00:00:00

abstract：:High-affinity uptake of norepinephrine (NE) and dopamine (DA) were determined in synaptosomes of brain regions from four genetically related inbred rat strains, all derived from the Wistar-Kyoto rat: SHR, WKY, WKHA and WKHT strains. SHRs express hypertension and hyperactivity, WKHAs express hyperactivity alone, WKHTs ...

journal_title：Brain research

authors： Hendley ED,Fan XM

更新日期：1992-07-17 00:00:00

abstract：:The effects of natural (mechanical and gustatory) stimulation of the nasopharynx or electrical stimulation of the pharyngeal branch of the glossopharyngeal (PH-IXth) nerve on the changes in heart rate (HR) and arterial blood pressure (BP) were investigated in paralyzed and anesthetized rats. Afferent responses in the ...

journal_title：Brain research

authors： Hanamori T,Ishiko N

更新日期：1993-08-13 00:00:00

abstract：:Abnormally hyperphosphorylated tau is the major protein component of neurofibrillary tangles, the characteristic lesion of Alzheimer's disease (AD). Protein phosphatases (PP) type 1 (PP-1), type 2A (PP-2A) and type 2B (PP-2B) appear to be involved in the regulation of tau phosphorylation. The incidence of neurofibrill...

journal_title：Brain research

authors： Gong CX,Shaikh S,Grundke-Iqbal I,Iqbal K

更新日期：1996-11-25 00:00:00

abstract：:The retinohypothalamic tract, a monosynaptic retinal projection to the suprachiasmatic nucleus (SCN), is the path by which light entrains the circadian system to the external photoperiod. Serotonergic neurons in the mesencephalic median raphe nucleus (MnR) also give rise to a major SCN afferent projection. The present...

journal_title：Brain research

authors： Muscat L,Tischler RC,Morin LP

更新日期：2005-05-17 00:00:00

abstract：:The neurotoxin alpha-latrotoxin elicits spontaneous exocytosis of neurotransmitter from neurons and peptide hormones from endocrine cells. While the mechanism of action is not fully understood, both Ca(2+)-dependent and Ca(2+)-independent pathways participate in the facilitation of release, with the relative contribut...

journal_title：Brain research

authors： Hlubek M,Tian D,Stuenkel EL

更新日期：2003-11-28 00:00:00

abstract：:Systemic injection of kainic acid (KA) in adult rat elicits a pattern of neuronal pathology which exhibits several features of human temporal lobe epilepsy. KA-induced seizure activity is accompanied by the activation of the calcium-dependent protease calpain in limbic structures. In the present study, we evaluated th...

journal_title：Brain research

authors： Bi X,Chang V,Siman R,Tocco G,Baudry M

更新日期：1996-07-08 00:00:00

abstract：:Tissue damage induces acute pain but also long-term central modifications that can affect the behavioral and neuronal responses to a second painful stimulus. To study the effects of female gonadal hormones on the responses to repetition of a nociceptive stimulus, we subjected adult female rats to the formalin test. Th...

journal_title：Brain research

authors： Ceccarelli I,Fiorenzani P,Massafra C,Aloisi AM

更新日期：2006-08-23 00:00:00

abstract：:The medial nucleus of the amygdala, bed nucleus of the stria terminalis, and medial preoptic area appear to mediate steroidal regulation of mating behavior in male rodents. The mechanism of action has not been determined. One way testosterone could enhance neuronal function is by increasing neurotransmitter levels, th...

journal_title：Brain research

authors： Swann JM,Newman SW

更新日期：1992-09-11 00:00:00