Abstract:
:The effects of natural (mechanical and gustatory) stimulation of the nasopharynx or electrical stimulation of the pharyngeal branch of the glossopharyngeal (PH-IXth) nerve on the changes in heart rate (HR) and arterial blood pressure (BP) were investigated in paralyzed and anesthetized rats. Afferent responses in the PH-IXth nerve were also investigated. Electrical stimulation of the PH-IXth nerve elicited a tachycardia and an increase in BP. Among the gustatory (1.0 M NaCl, 0.03 M HCl, 0.03 M QHCl, 1.0 M sucrose, H2O, and 0.9% NaCl) and mechanical stimuli applied to the nasopharynx, 1.0 M sucrose and 0.9% NaCl were ineffective in changing HR and BP; the rest of the stimuli were strongly effective as was the case with electrical stimulation of the PH-IXth nerve. Responses were evoked in the PH-IXth nerve by nasopharyngeal stimulation with the stimuli which were effective in producing cardiovascular responses. On the other hand, 1.0 M sucrose and 0.9% NaCl, which were ineffective stimuli for cardiovascular responses, did not produce any response in the PH-IXth nerve. There was a high correlation between the magnitude of the responses in the PH-IXth nerve and those of the cardiovascular system. These results indicate that gustatory and mechanical information carried in the PH-IXth nerve innervating the nasopharynx plays an important role in cardiovascular regulation as well as the sense of taste.
journal_name
Brain Resjournal_title
Brain researchauthors
Hanamori T,Ishiko Ndoi
10.1016/0006-8993(93)91614-xsubject
Has Abstractpub_date
1993-08-13 00:00:00pages
214-22issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(93)91614-Xjournal_volume
619pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::Most experimental spinal cord injury studies described to date have relied on a limited number of injury gradations, and have tacitly assumed that outcome (functional, histological, and/or neurophysiological) is a monotonically graded function of injury severity. In contrast, the present study provides evidence that f...
journal_title:Brain research
pub_type: 杂志文章
doi:
更新日期:1996-08-05 00:00:00
abstract::Magnetic resonance spectroscopy (MRS) has demonstrated age-related changes in brain metabolites that may underlie micro-structural brain changes, but few studies have examined their relationship with cognitive decline. We performed a cross-sectional study of brain metabolism and cognitive function in 82 healthy adults...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.06.027
更新日期:2007-08-20 00:00:00
abstract::The effects of acute and chronic phencyclidine (PCP) administration on neurotensin-like immunoreactivity (NTLI) were investigated in discrete regions of rat brain. Both acute and chronic administration of PCP induced high locomotor activity, stereotypy and ataxia. On PCP administration, NTLI decreased significantly in...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91601-4
更新日期:1985-05-06 00:00:00
abstract::Breathing oxygen at sufficiently elevated pressures can trigger epileptiform seizures. Therefore, we tested the hypothesis that pre-treatment with FDA-approved antiepileptic drugs could prevent seizure onset in hyperoxia at 5 atmospheres absolute. We selected drugs from two putative functional categories, Na+-channel ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2016.12.032
更新日期:2017-02-15 00:00:00
abstract::Endogenous opioids play a role in the regulation of LH-RH neurosecretion throughout the estrous cycle and during the preovulatory LH surge on proestrus. Experimental evidence suggests that opioid influence may be altered with age, and it has been hypothesized that these alterations may contribute to the loss of regula...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)91717-7
更新日期:1993-01-22 00:00:00
abstract::The distribution of retinal ganglion cells (RGCs) providing input to the thalamofugal visual system in the pigeon was studied with an anatomical transneuronal transport technique using the fluorescent dye rhodamine beta-isothiocyanate (RITC). Unilateral injections of RITC made into the telencephalic visual Wulst resul...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.04.091
更新日期:2006-07-07 00:00:00
abstract::Intrinsic membrane properties, voltage-dependent sodium and voltage-dependent potassium currents of area postrema neurons in culture have been characterized with respect to their voltage dependence, time dependence and sensitivity to specific blocking agents. The area postrema is a hindbrain circumventricular organ wh...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)01159-5
更新日期:1995-12-24 00:00:00
abstract::Body temperature changes and heat shock protein (HSP-72) induction in the caudate nucleus were studied in female C57BL/6N mice pretreated with ibogaine (50 mg/kg) and sacrificed 48 h. after a single dose of methamphetamine (20 mg/kg). Methamphetamine injection resulted in hyperthermia and induced HSP-72 expression, wh...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(99)01154-3
更新日期:1999-03-27 00:00:00
abstract::The kindling process represents a progressively augmenting electrical and behavioral response to brain stimulation, that has been proposed as a model for the development of epileptogenesis. The first experiment examined the effects of hypophysectomy on the kindling process. The effects of hypophysectomy were found to ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(79)91032-1
更新日期:1979-06-22 00:00:00
abstract::The present study has examined the involvement of sensory neurotransmitters in activating neurones in the trigeminal nucleus caudalis following stimulation of the trigeminovascular system in anaesthetised guinea-pigs. Electrical stimulation of the right trigeminal ganglion produced a unilateral expression of Fos-like ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)00930-x
更新日期:1997-11-14 00:00:00
abstract::In the present study, we assessed the beneficial synergistic effects of concurrent treatment with low doses of cilostazol and probucol against focal cerebral ischemic infarct in rats. The ischemic infarct induced by 2-h occlusion of middle cerebral artery (MCA) and 22-h reperfusion was significantly reduced in rat bra...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2007.04.051
更新日期:2007-07-09 00:00:00
abstract::With the increasing worldwide incidence of Alzheimer's disease (AD), there is a critical need for the discovery of more effective diagnostic methods. However, development of diagnostic tools in AD has been hindered by obstacles such as the absence of exact biomarkers. Apoptosis caused by amyloid-β (Aβ) plays an import...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2016.06.041
更新日期:2016-09-01 00:00:00
abstract::Monkeys were trained to depress a hold key for a period of 2 sec. After this hold period, either a red or a green cue lamp appeared in random sequence. The red lamp required the monkey to move his hand from the hold key to a target button within 1 sec of the cue presentation. The green lamp required continued depressi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(76)90986-0
更新日期:1976-01-09 00:00:00
abstract::We suggested previously that increases in the extracellular [Ca2+] or [Mg2+] lengthen miniature end-plate currents (m.e.p.c.s.) because the divalent cations decrease the negative surface potential on the end-plate, and thereby increase the voltage drop within the membrane. The increased voltage drop would lengthen the...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)91065-4
更新日期:1982-06-10 00:00:00
abstract::Distribution of somatostatin (SS) immunoreactivity was observed in the preoptic-anterior hypothalamus (PO-AH) of the female rat brain. Six specific rabbit antibodies A (SS-14), B (SS-28), C (SS-28 complete), D (SS 14 and SS-28 both), E (SS preprohormone) and F (GHRH) were used for immunostaining using Avidin-Biotin Co...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)03164-4
更新日期:2001-05-11 00:00:00
abstract::We report here the results of an autoradiographic analysis of the postnatal development of the hippocampal glucocorticoid receptor system in the rat brain. Quantitative analysis of the autoradiograms revealed a varied pattern of gradual development towards adult receptor concentrations during the second week of life. ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(85)90260-3
更新日期:1985-02-01 00:00:00
abstract::We have previously reported the first successful production of monoclonal antibodies against the cholinergic neuronal marker, choline acetyltransferase (ChAT). We now report some inter-and intraspecies cross-reactivity studies of the monoclonal antibody AB1. This antibody reacted most strongly with bovine ChAT and wea...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90889-7
更新日期:1982-02-25 00:00:00
abstract::The location of edema and territory of extravasation of serum protein were examined in the white matter of cats with different forms of intracranial pathology following an impact-acceleration injury to the head. Edema was tested with an organic density gradient and Evans blue dye was used as a marker for breakdown of ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)91611-7
更新日期:1985-06-24 00:00:00
abstract::Cerebellar Purkinje neurons possess AMPA ((RS)-alpha-amino-3-hydroxyl-5- methyl-4-isoxazolepropionic acid)-sensitive ionotropic glutamate receptors (AMPA GluRs) and ACPD ((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid)-sensitive metabotropic glutamate receptors (mGluRs). The contributions of these receptors to resp...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(93)91186-v
更新日期:1993-12-17 00:00:00
abstract::In the past few years a steadily increasing number of substances have been suggested to qualify as sleep-inducing factors. Most 'sleep factors' appear to exert their effects on slow-wave sleep. Recently, however, it has been shown that the cerebrospinal fluid (CSF) of sleep-deprived cats may contain a rapid eye moveme...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)91561-1
更新日期:1986-10-15 00:00:00
abstract::Immunocytochemical and immunoblotting technique have been used to characterize the antigens recognized by two monoclonal antibodies (MAbs C6 and D5) produced against dissociated cells from punches of neonatal supraoptic (SON) and paraventricular (PVN) hypothalamic nuclei of the rat. Peroxidase immunocytochemistry reve...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(91)91281-5
更新日期:1991-04-05 00:00:00
abstract::Structural and functional alterations of the putamen have been reported in patients with attention deficit hyperactivity disorder (ADHD), but the functional relationships between this area and other brain regions are seldom explored. In the present study, seed-based correlation analyses were performed in the resting-s...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2009.08.029
更新日期:2009-12-15 00:00:00
abstract::Electrical stimulation of the subfornical organ (SFO) in urethane anesthetized male Sprague-Dawley rats was associated with intensity and frequency dependent increases in arterial blood pressure. Stimulation in the hypothalamic paraventricular nucleus (PVN) also evoked increases in arterial blood pressure. Electrolyti...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)90443-8
更新日期:1984-07-09 00:00:00
abstract::The recruitment of performance control was recently explained in terms of the detection of response conflict. One recent hypothesis claims that the degree of response conflict is reflected in an electroencephalographical component, the Error Negativity (Ne). Indeed, in the framework of simulations, variations of the N...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.04.004
更新日期:2006-06-20 00:00:00
abstract::Electrical activities of thin hippocampal sections of the guinea pig were studied in vitro during and after administration of black widow spider venom (BSV). In CA3 neurons, BSV induced spontaneous discharges which were suppressed by Co2+ or Mn2+. During BSV administration, trains of potential changes resembling excit...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90103-2
更新日期:1982-07-29 00:00:00
abstract::A classification of the parietal corticofugal neurons was performed in cats under Nembutal anesthesia. Eighty-eight neurons were identified with antidromic activation by the pontine stimulation. Thirteen neurons were furthermore identified with intracellular HRP staining. In these neurons, we found the close correlati...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(85)90895-9
更新日期:1985-11-11 00:00:00
abstract::Experimental allergic encephalomyelitis (EAE) was induced in young male Lewis rats. Blood-brain barrier permeability to radiotracers of different molecular sizes was studied at intervals after induction using a tissue sampling technique. The results were correlated to the clinical picture and to the histological appea...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)90249-x
更新日期:1984-06-08 00:00:00
abstract::The cortical afferents from individual laminae of the dorsal lateral geniculate nucleus (LGN) were studied using both light and electron microscope autoradiography. In area 17, the A geniculate laminae (A and A1) had two main bands of projection, one extending from the bottom of IVc to the deepest cells in layer III, ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(76)90002-0
更新日期:1976-08-20 00:00:00
abstract::The non-cholinergic excitatory potential elicited in neurons of the isolated inferior mesenteric ganglia was depressed by bath application of Met- or Leu-enkephalin and enhanced by naloxone or naltrexone. The membrane depolarization induced by exogenously applied putative transmitter substance P was not appreciably af...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(82)90211-6
更新日期:1982-03-04 00:00:00
abstract::Previous work has shown a relatively high turnover of adrenaline in the mediobasal hypothalamus during the critical period (15.00-17.00 h) of the proestrous rat. We now report that this high level of adrenergic activity can be detected in the median eminence (turnover rate 1.62 +/- 0.36 pg/micrograms protein/h) rather...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(84)90307-x
更新日期:1984-12-10 00:00:00