Abstract：
:Experiments were performed in ambulating decerebrate ferrets to examine the activity of up to 6 simultaneously recorded Purkinje cells oriented sagittally during unperturbed and perturbed locomotion using a new analytical technique, the real-time postsynaptic response (RTPR), which permits a trial-by-trial assessment of the action of the recorded neurons on a simulated cerebellar nuclear cell. The data illustrate that the responsiveness of the Purkinje cells located in a specific region of lobules V and VI is most dramatically modulated by the perturbations of the locomotor cycle and that this responsiveness in the perturbed trials is related to the degree of synchrony of the activated climbing fiber inputs to the cells of the set. The data were interpreted as supporting the gain change hypothesis of climbing fiber function.
journal_name
Brain Resjournal_title
Brain researchauthors
Lou JS,Bloedel JRdoi
10.1016/0006-8993(86)91646-xsubject
Has Abstractpub_date
1986-02-19 00:00:00pages
340-4issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(86)91646-Xjournal_volume
365pub_type
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