Abstract:
:In the dorsal lateral geniculate nucleus (LGN) of the adult cat there is no evidence for translaminar sprouting of retinal axons to fill sites freed of retinal endings from the other eye. We tested the possibility that retinal axons will sprout to fill denervated retinal sites within laminae of the monkey LGN. In 4 monkeys, retinal ganglion cell axons from either the upper or lower half of the retina were destroyed. To maximize the potential for sprouting in the LGN, on one side of the brain the LGN cells to which the remaining retinal axons normally project were removed by ablation of the appropriate portion of the striate cortex. Three months later the eye receiving the retinal lesion was injected with [3H]proline and the retinal projection to the LGN on both sides of the brain was studied using autoradiography. We found no evidence of intralaminar sprouting of retinal axons either in the normal LGN or in the LGN in which the usual targets of retinal axons had been removed.
journal_name
Brain Resjournal_title
Brain researchauthors
Stelzner DJ,Keating EGdoi
10.1016/0006-8993(77)90721-1subject
Has Abstractpub_date
1977-05-06 00:00:00pages
201-10issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(77)90721-1journal_volume
126pub_type
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