Reduced expression of complexins I and II in rats bred for learned helplessness.

abstract：:A procedure has been developed for the stable long-term recording of nerve signals in unanesthetized mammals, which should have wide application in basic research on the nervous system and also in clinical areas such as the derivation of control signals for powered prostheses. Methods are fully described for construct...

journal_title：Brain research

authors： Stein RB,Nichols TR,Jhamandas J,Davis L,Charles D

更新日期：1977-06-03 00:00:00

abstract：:We found that local perfusion of COA-Cl (0.1, 0.4, or 1.0 mM) into the dorsal striatum of living mice produced a significant and dose-dependent increase in extracellular DA levels, with the highest dose of 1.0 mM COA-Cl producing an approximately 5-fold increase in DA. Consistent with in vivo findings, 0.1 and 0.2 mM ...

journal_title：Brain research

authors： Jamal M,Tsukamoto I,Takata M,Ito A,Tanaka N,Miki T,Takakura A,Ameno K,Kubota Y,Konishi R,Kinoshita H

更新日期：2019-03-01 00:00:00

abstract：:The contribution of the activity of afferent fiber filaments to pain and hyperalgesia after administration of a plantar injection of interleukin-1 beta (IL-1 beta) to the hind-paw skin was investigated by recording action potentials of the rat dorsal root in response to mechanical and thermal stimuli. Touch stimuli we...

journal_title：Brain research

authors： Fukuoka H,Kawatani M,Hisamitsu T,Takeshige C

更新日期：1994-09-19 00:00:00

abstract：:The rat hippocampus contains an acidic macromolecular neurotrophic factor (NTF) which supports the survival of cultured chick ciliary ganglion cells. Hippocampal NTF increases approximately 2-fold from birth to adulthood with no further change with aging. Disruption of extrinsic inputs to the hippocampus from the ento...

journal_title：Brain research

authors： Heacock AM,Schonfeld AR,Katzman R

更新日期：1986-01-22 00:00:00

abstract：:Cyclic nucleotide phosphodiesterase-4 (PDE4) is a component of signaling pathways involved in the mediation of antidepressant activity. Of the four PDE4 subtypes, PDE4D appears to be of particular importance, given the finding that PDE4D-deficient mice exhibit an antidepressant-like behavioral phenotype. In mouse hipp...

journal_title：Brain research

authors： Dlaboga D,Hajjhussein H,O'Donnell JM

更新日期：2006-06-22 00:00:00

abstract：:We previously observed that substance P (SP) levels in the rat superior cervical ganglion (SCG) rise sharply when the ganglion is maintained in vitro. To define the cellular localization of SP, sections of cultured SCG were stained for the possible dual presence of SP and tyrosine hydroxylase (TOH). Immunoreactivity t...

journal_title：Brain research

authors： Bohn MC,Kessler JA,Adler JE,Markey K,Goldstein M,Black IB

更新日期：1984-04-30 00:00:00

abstract：:Myelin of several Caudata (Urodela) species appears to be unique in the fact that it lacks hydroxycerebrosides and hydroxysulfatides although it contains their non-hydroxy counterparts. Comparison of the nerve conduction velocities in the Urodeles Necturus (salamander) and Notophthalmus (newt) with that in a reptile, ...

journal_title：Brain research

authors： Ki PF,Kishimoto Y,Lattman EE,Stanley EF,Griffin JW

更新日期：1985-10-14 00:00:00

abstract：:Lesions to the ventromedial hypothalamus (VMH) inhibit receptive sexual behavior in the whiptail lizard, Cnemidophorus uniparens, an all-female species. All lesions to the VMH that effectively abolished receptivity specifically damaged the dorsal lateral VMH, an area containing high concentrations of estrogen receptor...

journal_title：Brain research

authors： Kendrick AM,Rand MS,Crews D

更新日期：1995-05-22 00:00:00

abstract：:Fetal exposure to dexamethasone (DEX) alters brain plasticity and cognitive functions during adulthood in a sex-dependent manner. The mechanisms underlying such long-lasting sex-dependent change of prenatal DEX is not well understood. The p73 gene plays an important role in brain development. It encodes for two protei...

journal_title：Brain research

authors： Abul M,Al-Bader MD,Mouihate A

更新日期：2019-03-15 00:00:00

abstract：:We have previously found that crocin (crocetin di-gentiobiose ester) antagonizes the inhibitory effect of ethanol on long-term potentiation in the rat hippocampus in vivo and in vitro. To explore mechanisms underlying the antagonism of crocin against ethanol, we investigated the effects of ethanol and crocin on synapt...

journal_title：Brain research

authors： Abe K,Sugiura M,Shoyama Y,Saito H

更新日期：1998-03-16 00:00:00

abstract：:Maternal cigarette use during pregnancy is associated with increased incidence of neural impairments in offspring, but nicotine's unique contribution to any neuropathology remains unclear, and nicotine's neurodevelopmental effects assessed in animal models vary with concentration. During ontogenesis, the chick oculomo...

journal_title：Brain research

authors： Wielgus JJ,Corbin Downey L,Ewald KW,Hatley ME,Wilson KC,Yeilding RH

更新日期：2004-03-12 00:00:00

abstract：:Intracellular staining with recording micropipettes filled with a Procion yellow solution was attempted on 11 lateral geniculate neurons of chloralose-anesthetized cats for the purpose of correlating electrophysiologically identified cell types with morphologically identified cell types. Five neurons were successfully...

journal_title：Brain research

authors： Ogawa T,Takimori T,Takahashi Y

更新日期：1978-01-06 00:00:00

abstract：:The uptake and efflux of 36Cl in the lateral ventricle choroid plexus of 1-7-week-old rats were measured to determine if Cl transport changed with age and if such transport responded to inhibitors of CSF secretion and ion transport. The steady-state (30 min) Cl uptakes were 148 +/- 9.4 nmol.mg-1 dry weight at 1 week a...

journal_title：Brain research

authors： Preston JE,Dyas M,Johanson CE

更新日期：1993-10-08 00:00:00

abstract：INTRODUCTION:Apathy is the most common neuropsychiatric syndrome in behavioral variant frontotemporal dementia (bvFTD), and encompasses cognitive, behavioral and affective symptoms. The neural basis of apathy in bvFTD is not completely understood. Previous neuroimaging studies have poorly considered executive impairmen...

journal_title：Brain research

authors： Gonçalves SAB,Caramelli P,Mariano LI,Guimarães HC,Gambogi LB,Resende EPF,Teixeira AL,de Souza LC

更新日期：2020-06-15 00:00:00

abstract：:In the adult central nervous system (CNS), GABA and glycine (Gly) are predominant inhibitory neurotransmitters, negatively regulating glutamatergic transmission. In the immature CNS, on the other hand, they act as trophic factors, mediating morphogenesis. In the present study, to investigate their involvement in axona...

journal_title：Brain research

authors： Tatetsu M,Kim J,Kina S,Sunakawa H,Takayama C

更新日期：2012-03-29 00:00:00

abstract：:This study examines possible changes in energy demands by developing neural crest cells in vitro using cytochrome oxidase (C.O.) histochemistry and immunohistochemical labeling of adrenergic (autonomic) cells and primary sensory neurons. Cytochrome oxidase is a key enzyme for oxidative metabolism and energy production...

journal_title：Brain research

authors： Liu S,Wilcox DA,Sieber-Blum M,Wong-Riley M

更新日期：1990-12-10 00:00:00

abstract：:The distribution of radioactivity after injection of [3H]testosterone was studied in the forebrain of adult mice by thaw-mount autoradiography. Nuclear labeling was high in neurons in the dorsal part of the medial nucleus of the amygdala and in the dorsocaudal part of the bed nucleus of the stria terminalis. Low nucle...

journal_title：Brain research

authors： Schleicher G,Stumpf WE,Morin JK,Drews U

更新日期：1986-11-12 00:00:00

abstract：:Murine cortical cell cultures deprived of glucose for 6-8 h developed extensive neuronal degeneration, apparent both morphologically and by efflux of lactate dehydrogenase to the bathing medium. This neuronal damage could be substantially reduced by addition of D-2-amino-5-phosphonovalerate (D-APV), in a concentration...

journal_title：Brain research

authors： Monyer H,Goldberg MP,Choi DW

更新日期：1989-04-03 00:00:00

abstract：:The vascular changes in the hippocampus and neocortex during kainic acid-induced seizures were investigated in control rats and in rats with chronic, bilateral, cervical sympathectomy. Seizures were induced in unanesthetized, spontaneously breathing rats. The increase in blood flow in the hippocampus of the sympathect...

journal_title：Brain research

authors： Rigaud AS,Pinard E,Borredon J,Seylaz J

更新日期：1990-11-05 00:00:00

abstract：:We tested the hypothesis that a single systemic injection of 380 mg/kg of the muscarinic agonist pilocarpine would produce more diffuse and severe seizure-induced brain damage than a single injection of lithium (3 mEq/kg) followed 4 h later by < 1/10 the dosage of pilocarpine. The hypothesis was not supported; the pat...

journal_title：Brain research

authors： Bureau YR,Peredery O,Persinger MA

更新日期：1994-06-20 00:00:00

abstract：:Previous studies from our laboratory suggest that apolipoprotein (apoE), a lipid transporting protein, facilitates olfactory nerve regeneration. We have shown that apoE is enriched in the olfactory nerve and around the glomeruli of the olfactory bulb (OB). The studies reported herein were undertaken to identify possib...

journal_title：Brain research

authors： Nathan BP,Nannapaneni S,Gairhe S,Nwosu I,Struble RG

更新日期：2007-03-16 00:00:00

abstract：:Insulin and the insulin-like growth factors (IGFs) may directly affect the growth, development, and maintenance of the vertebrate nervous system. Previous in vitro studies have focused on embryonic nervous tissue. In this study the effects of insulin, IGF-I, IGF-II and nerve growth factor (NGF) on regeneration and neu...

journal_title：Brain research

authors： Fernyhough P,Willars GB,Lindsay RM,Tomlinson DR

更新日期：1993-04-02 00:00:00

abstract：:The amplitude of anterior neocortical EEG slow-waves (0.5-4 Hz) measured during quiet waking, drowsy (WS) and synchronized sleep (S) states showed slow rhythmic oscillations in WS and S similar to those previously reported in midbrain reticular neurons (periods of 8-12 s). Abrupt changes in slow rhythms of unit discha...

journal_title：Brain research

authors： Oakson G,Steriade M

更新日期：1983-06-20 00:00:00

abstract：:In a recent study in the tiger salamander, Ambystoma tigrinum, were demonstrated topographic patterns of responsivity across the olfactory epithelium which were characteristic for each odorant. The present study was initiated to investigate whether these patterns remain constant when odorant concentration is varied. O...

journal_title：Brain research

authors： Mackay-Sim A,Shaman P

更新日期：1984-04-16 00:00:00

abstract：:We previously found that the dopamine D3 receptor can be split at the third cytoplasmic loop into two fragments (D3trunk and D3tail), and that the mixture of the two fragments retains the binding and functional activity of the wild type receptor. The dopamine D3 receptor gene gives rise to several inactive receptor sp...

journal_title：Brain research

authors： Scarselli M,Novi F,Corsini GU,Maggio R

更新日期：2003-10-17 00:00:00

abstract：:Type 2 iodothyronine deiodinase, an enzyme involved in the conversion of thyroxin to the biologically active 3,5, 3'-triiodothyronine, is highly concentrated in a group of specialized ependymal cells, tanycytes, lining the wall and floor of the third ventricle. As this distribution is highly reminiscent of the distrib...

journal_title：Brain research

authors： Fekete C,Mihály E,Herscovici S,Salas J,Tu H,Larsen PR,Lechan RM

更新日期：2000-04-17 00:00:00

abstract：:The purposes of this research were to quantify gravity receptor function in inbred mouse strains and compare vestibular and auditory function for strain- and age-matched animals. Vestibular evoked potentials (VsEPs) were collected for 19 inbred strains at ages from 35 to 389 days old. On average, C57BL/6J (35 to 190 d...

journal_title：Brain research

authors： Jones SM,Jones TA,Johnson KR,Yu H,Erway LC,Zheng QY

更新日期：2006-05-26 00:00:00

abstract：:Electrical activities of thin hippocampal sections of the guinea pig were studied in vitro during and after administration of black widow spider venom (BSV). In CA3 neurons, BSV induced spontaneous discharges which were suppressed by Co2+ or Mn2+. During BSV administration, trains of potential changes resembling excit...

journal_title：Brain research

authors： Yamamoto C,Matsui H

更新日期：1982-07-29 00:00:00

abstract：:The effects of intracellular injection of TEA on the stretch-induced response of the slowly adapting stretch receptor of the crayfish have been examined to determine the contribution of an outward potassium current to the early adaptation of the neuron. Intracellular recording techniques including potential clamp meas...

journal_title：Brain research

authors： Ottoson D,Swerup C

更新日期：1985-06-10 00:00:00

abstract：:The effect of central and peripheral administration of a nitric oxide synthase inhibitor, N-nitro-L-arginine methyl ester (L-NAME), on morphine hyperthermia was studied in male Sprague-Dawley rats. The first series of experiments examined the effect of subcutaneous (s.c.) administration of L-NAME on the hyperthermia i...

journal_title：Brain research

authors： Benamar K,Xin L,Geller EB,Adler MW

更新日期：2001-03-16 00:00:00