Simultaneous expression of the SP-peptidergic and noradrenergic phenotypes in rat sympathetic neurons.

Abstract:

:We previously observed that substance P (SP) levels in the rat superior cervical ganglion (SCG) rise sharply when the ganglion is maintained in vitro. To define the cellular localization of SP, sections of cultured SCG were stained for the possible dual presence of SP and tyrosine hydroxylase (TOH). Immunoreactivity to both SP and TOH was present in the majority of principal neurons. This observation suggests that principal sympathetic neurons can express simultaneously both the noradrenergic and SP-peptidergic phenotypes.

journal_name

Brain Res

journal_title

Brain research

authors

Bohn MC,Kessler JA,Adler JE,Markey K,Goldstein M,Black IB

doi

10.1016/0006-8993(84)91442-2

subject

Has Abstract

pub_date

1984-04-30 00:00:00

pages

378-81

issue

2

eissn

0006-8993

issn

1872-6240

pii

0006-8993(84)91442-2

journal_volume

298

pub_type

杂志文章
  • Neurodegeneration caused by expression of human truncated tau leads to progressive neurobehavioural impairment in transgenic rats.

    abstract::Human truncated tau protein is an active constituent of the neurofibrillary degeneration in sporadic Alzheimer's disease. We have shown that modified tau protein, when expressed as a transgene in rats, induced AD characteristic tau cascade consisting of tau hyperphosphorylation, formation of argyrophilic tangles and s...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.10.085

    authors: Hrnkova M,Zilka N,Minichova Z,Koson P,Novak M

    更新日期:2007-01-26 00:00:00

  • Striatal dopamine metabolism in living monkeys examined by positron emission tomography.

    abstract::Positron emission tomography, using the dopa analogue [18F]6-fluoro-L-dopa, has been used to depict the neostriatum in living monkeys. The amount of 18F that accumulated preferentially in the striatum could be augmented by a peripheral decarboxylase inhibitor. Striatal 18F could also be discharged with reserpine. This...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)91187-3

    authors: Garnett S,Firnau G,Nahmias C,Chirakal R

    更新日期:1983-11-28 00:00:00

  • Cardiovascular effects of substance P and capsaicin microinjected into the nucleus tractus solitarii of the rat.

    abstract::This report deals with the effect of substance P (SP) and capsaicin on blood pressure and heart rate after administration into different sites of the nucleus tractus solitarii (NTS) of urethane-anesthetized rats. Microinjection of SP at 6 different coordinates throughout the NTS showed 3 sites where SP administration ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(87)90938-3

    authors: Lukovic L,de Jong W,de Wied D

    更新日期:1987-10-06 00:00:00

  • Axonal growth and glial migration from co-cultured hippocampal and septal slices into fibrin-fibronectin-containing matrix of peripheral regeneration chambers: a light and electron microscope study.

    abstract::In order to investigate whether a fibrin-fibronectin-containing matrix of a peripheral regeneration chamber could promote the growth of central nervous system neurons, hippocampal and septal slices were co-cultured in the presence of this acellular substrate. In introducing the peripheral matrix into a 2-mm-long tube ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)90506-q

    authors: Knoops B,Hubert I,Hauw JJ,van den Bosch de Aguilar P

    更新日期:1991-02-01 00:00:00

  • Kainic acid-induced seizures: potentiation by alpha-methyl-p-tyrosine.

    abstract::We have investigated the influence of central noradrenergic and dopaminergic systems on the susceptibility of rats to seizures in the kainic acid (KA)-model of epilepsy. In the dose range of 0.75 to 10 mg/kg s.c., KA dose-dependently induced characteristic behavioural changes. Partial depletion of noradrenaline (NA) a...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)90219-9

    authors: Baran H,Hörtnagl H,Hornykiewicz O

    更新日期:1989-08-28 00:00:00

  • Altered functional connectivity in patients with subcortical ischemic vascular disease: A resting-state fMRI study.

    abstract::Patients with subcortical ischemic vascular disease (SIVD) may hold a high risk of cognitive impairment (CI) by affecting the functional connectivity (FC) of resting-state networks (RSNs). Current studies have mainly focused on the patients with CI but have ignored the prodromal stage when people suffered subcortical ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2019.03.022

    authors: Liu X,Chen L,Cheng R,Luo T,Lv F,Fang W,Gong J,Jiang P

    更新日期:2019-07-15 00:00:00

  • Nicotinic acetylcholine receptor-mediated synaptic potentials in rat neocortex.

    abstract::In the neocortex, fast excitatory synaptic transmission can typically be blocked by using excitatory amino acid (EAA) receptor antagonists. In recordings from layer II/III neocortical pyramidal neurons, we observed an evoked excitatory postsynaptic potential (EPSP) or current (EPSC) in the presence of EAA receptor ant...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)03076-6

    authors: Chu ZG,Zhou FM,Hablitz JJ

    更新日期:2000-12-29 00:00:00

  • Two-dimensional gel electrophoresis of proteins in rapid axoplasmic transport.

    abstract::Two-dimensional electrophoresis of proteins has allowed high resolution analysis of the protein species rapidly transported in the frog sciatic nerve. The 7th, 8th and 9th dorsal root ganglia were selectively labeled with [3H]leucine or [35S]methionine in one compartment of a lucite chamber. Transport of TCA-precipita...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(78)90155-5

    authors: Stone GC,Wilson DL,Hall ME

    更新日期:1978-04-14 00:00:00

  • The basis and functional role of the late EMG activity in human forearm muscles following wrist displacement.

    abstract::The present paper examines the hypothesis that the long latency EMG activity produced by muscle stretch is the result of long loop reflex pathways involved in the control of limb stiffness. We recorded the cerebral responses and late EMG activity in agonist and antagonist muscles following sudden stretch of the wrist ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(92)91159-c

    authors: Goodin DS,Aminoff MJ

    更新日期:1992-08-28 00:00:00

  • Enhanced gamma-band activity in ADHD patients lacks correlation with memory performance found in healthy children.

    abstract::Previous electrophysiological as well as imaging research has contributed to the understanding of impairments in attention, executive functions, and memory in patients with attention-deficit/hyperactivity disorder (ADHD). However, there is a lack of studies investigating ADHD related differences in the gamma range of ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2008.06.023

    authors: Lenz D,Krauel K,Schadow J,Baving L,Duzel E,Herrmann CS

    更新日期:2008-10-15 00:00:00

  • The development of neurons in the cat perigeniculate nucleus and reticular nucleus of the thalamus.

    abstract::The postnatal development of soma size and cytochrome oxidase activity was examined in the perigeniculate nucleus (PGN) and reticular nucleus of the thalamus (RNT). Neurons in the PGN and RNT exhibited a rapid increase in soma size between 2 and 4 weeks of age. During this period of cell growth there is an increase in...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0165-3806(87)90047-2

    authors: Murakami DM,Condo GJ,Wilson PD

    更新日期:1987-10-01 00:00:00

  • Release of D-[3H]aspartate and [14C]GABA in rat hippocampus slices: effects of fatty acid-free bovine serum albumin and Ca2+ withdrawal.

    abstract::Extended incubation of hippocampus slices in the presence of fatty acid-free bovine serum albumin (FAF-BSA) strongly enhanced the release of D-[3H]aspartate and [14C]GABA induced by veratridine. Saturation of the FAF-BSA with oleic acid abolished the enhancing effect. Spontaneous release and K+-induced release were no...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)90687-7

    authors: Minc-Golomb D,Eimerl S,Levy Y,Schramm M

    更新日期:1988-08-09 00:00:00

  • ‬The expression of purinergic P2X4 and P2X7 receptors in selected mesolimbic structures during morphine withdrawal in rats.

    abstract::Morphine is one of the most potent analgesics used in medicine and it's long-term use is associated with the risk of the state of dependence. The cessation of chronic morphine administration leads to withdrawal signs which are associated with neurotransmitter dysregulations within mesolimbic system. Adenosine 5'-triph...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2019.05.025

    authors: Metryka E,Gutowska I,Kupnicka P,Tarnowski M,Tkacz M,Listos J,Talarek S,Barczak K,Chlubek D,Baranowska-Bosiacka I

    更新日期:2019-09-15 00:00:00

  • Rat olfactory neurons express a 200 kDa neurofilament.

    abstract::Neurofilament expression in peripheral olfactory neurons of adult rats was investigated by immunoblotting and immunohistochemistry using monoclonal antibodies specific for each of the 3 neurofilament proteins. Immunoblotting analysis of olfactory epithelium extracts demonstrated the presence of only the 200 kDa (NFH) ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(91)90416-s

    authors: Bruch RC,Carr VM

    更新日期:1991-05-31 00:00:00

  • Genetic causes of amyotrophic lateral sclerosis: new genetic analysis methodologies entailing new opportunities and challenges.

    abstract::The genetic architecture of amyotrophic lateral sclerosis (ALS) is being increasingly understood. In this far-reaching review, we examine what is currently known about ALS genetics and how these genes were initially identified. We also discuss the various types of mutations that might underlie this fatal neurodegenera...

    journal_title:Brain research

    pub_type: 杂志文章,评审

    doi:10.1016/j.brainres.2014.10.009

    authors: Marangi G,Traynor BJ

    更新日期:2015-05-14 00:00:00

  • Effect of aging on concentrations of D2-receptor-containing neurons in the rat striatum.

    abstract::Striatal D2 dopamine receptor concentrations were shown to decrease 30-35% during the lifespan of Wistar rats as assessed both radiochemically and autoradiographically. Binding densities and degree of age-change varied within the striatum; the latter ranging from 17 to 44% in 4 different regions. Overall neuronal loss...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(89)91108-6

    authors: Han Z,Kuyatt BL,Kochman KA,DeSouza EB,Roth GS

    更新日期:1989-10-02 00:00:00

  • Pre- and postsynaptic actions of valproic acid at the frog neuromuscular junction.

    abstract::The effect of valproic acid (VPA) on synaptic transmission was investigated at the frog neuromuscular junction using electrophysiological methods. The drug caused a dose-dependent decrease in the quantal content of the endplate potential (EPP) and a significant reduction in the input resistance of the postjunctional m...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(84)90393-7

    authors: Alkadhi KA,Banks FW

    更新日期:1984-07-23 00:00:00

  • Involvement of nigrostriatal dopamine neurons in the contraversive rotational behavior evoked by electrical stimulation of the lateral hypothalamus.

    abstract::This experiment was conducted to determine if nigrostriatal dopamine (DA) neurons are necessary for the contraversive rotational behavior evoked by electrical stimulation in the lateral hypothalamus. Rats were tested daily for electrical stimulation-induced rotational behavior (ESRB) for 5 days, and then given an inje...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)91508-2

    authors: Castañeda E,Robinson TE,Becker JB

    更新日期:1985-02-18 00:00:00

  • Electrophysiological evidence that the mediodorsal nucleus of the thalamus is a relay between the ventral pallidum and the medial prefrontal cortex in the rat.

    abstract::The neural connections from the ventral pallidum (VP) through the mediodorsal nucleus of the thalamus (MD) to the medial prefrontal cortex (MPC) were investigated. Extracellular recordings were made from 219 neurons in the medial and lateral portions of the MD and the VP and the MPC were stimulated. The most frequent ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)90811-x

    authors: Vives F,Mogenson GJ

    更新日期:1985-10-07 00:00:00

  • Localization of cholecystokinin-octapeptide-like-immunoreactivity in neurons cultured from rat cerebral cortex.

    abstract::Cholecystokinin-octapeptide-like-immunoreactivity (CCK-8-LI) is demonstrable by the indirect immunofluorescent technique in cerebral cortical neurons cultured from fetal rats. Prominent and widespread staining is seen in widely ramifying cellular processes throughout the cultures. Staining in neuronal cell bodies is e...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(84)91456-2

    authors: Delfs JR,Zhu CH,Dichter MA

    更新日期:1984-02-13 00:00:00

  • 6-[18F]fluoro-L-dihydroxyphenylalanine metabolism and positron emission tomography after catechol-O-methyltransferase inhibition in normal and hemiparkinsonian monkeys.

    abstract::Increased and sustained central delivery of L-dihydroxyphenylalanine (L-DOPA) is a desirable therapeutic strategy in Parkinson's disease. We investigated the effects of peripheral catechol-O-methyltransferase (COMT) inhibition, by the non-toxic drug nitecapone on the metabolism of 6-[18F]fluoro-L-dihydroxyphenylalanin...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90556-3

    authors: Miletich RS,Comi G,Bankiewicz K,Plunkett R,Adams R,Di Chiro G,Kopin IJ

    更新日期:1993-10-29 00:00:00

  • Penicillin-induced epileptic phenomena in the rabbit's neocortex II. Laminar specific generation of interictal spikes after the application of penicillin to different cortical depths.

    abstract::To elucidate the generation mechanisms of interictal spikes we analyzed the electrical events in the different layers of the rabbit's neocortex after application of penicillin to distinct cortical layers. Field potentials (FP) recorded simultaneously from all layers with a 16-fold micro-electrode-assembly were subject...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:

    authors: Pockberger H,Rappelsberger P,Petsche H

    更新日期:1984-09-10 00:00:00

  • Selective impairment of declarative memory following stimulation of dentate gyrus granule cells: a naloxone-sensitive effect.

    abstract::Albino rats received 10 s of sub-seizure electrical stimulation applied to the dentate gyrus granule cells immediately after acquisition of information on trial 1 of a 2-trial radial maze spatial memory task. Granule cell stimulation selectively reduced the probability of accessing information held in declarative memo...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(84)90166-5

    authors: Collier TJ,Routtenberg A

    更新日期:1984-09-24 00:00:00

  • Theta EEG oscillatory activity and auditory change detection.

    abstract::The mismatch negativity is an electrophysiological marker of auditory change detection in the event-related brain potential and has been proposed to reflect an automatic comparison process between an incoming stimulus and the representation of prior items in a sequence. There is evidence for two main functional subcom...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.07.079

    authors: Fuentemilla L,Marco-Pallarés J,Münte TF,Grau C

    更新日期:2008-07-18 00:00:00

  • Temporal profile of nestin expression after focal cerebral ischemia in adult rat.

    abstract::Nestin is an intermediate filament protein, transiently and abundantly expressed early in embryogenesis, e.g., in neuroepithelial cells, radial glia, germinal matrix cells and vascular cells. In the adult rat brain, nestin is only present in endothelial and select subventricular cells. We tested the hypothesis that af...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)01502-4

    authors: Li Y,Chopp M

    更新日期:1999-08-14 00:00:00

  • Ca2+ ionophore-induced apoptosis on cultured embryonic rat cortical neurons.

    abstract::The neurotoxicity of ionomycin, a Ca2+ ionophore, was investigated in cultured cortical neurons from embryonic rats. While about 90% of neurons survived 2 h after exposure to ionomycin, the surviving neurons had decreased by about 30 to 40% at 16 h. Both RNA and protein synthesis inhibitors blocked this neurotoxicity....

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)90317-4

    authors: Takei N,Endo Y

    更新日期:1994-07-25 00:00:00

  • Fos synthesis in identified magnocellular neurons varies with phenotype, stimulus, location in the hypothalamus and reproductive state.

    abstract::The present study compared Fos expression in identified hypothalamic magnocellular neurons in lactating and non-lactating female rats submitted to acute haemorrhage or 24 h of water deprivation, stimuli that induce the release of both oxytocin and vasopressin. Quantitative analysis of preparations doubly immunostained...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)90809-5

    authors: Fénelon VS,Theodosis DT,Poulain DA

    更新日期:1994-10-31 00:00:00

  • Sex-related difference in substance P level in rat anterior pituitary: a model of neonatal imprinting by testosterone.

    abstract::There was a distinct sex-related difference in the anterior pituitary level of substance P-like immunoreactivity (SP-LI) in adult rats; the anterior pituitaries of male rats contained a higher concentration of SP-LI than those of females. Neonatal castration (day 1) resulted in a marked decrease of the SP-LI level in ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)90863-6

    authors: Yoshikawa K,Hong JS

    更新日期:1983-08-29 00:00:00

  • Proportion of unmyelinated axons in rat molar and incisor tooth pulps following neonatal capsaicin treatment and/or sympathectomy.

    abstract::The occurrence of unmyelinated axons was examined ultrastructurally in rat molar and incisor root pulps of normal rats, of neonatally capsaicin-treated rats, of rats subjected to neonatal capsaicin treatment followed by resection of the superior cervical ganglion and of sympathectomized but otherwise normal rats. Foll...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)90533-1

    authors: Fried K,Aldskogius H,Hildebrand C

    更新日期:1988-10-25 00:00:00

  • Cerebral involvement in dehydration-induced natriuresis.

    abstract::Water deprivation caused daily urinary Na output to more than double in normal sheep, but caused no increase in Na excretion in sheep (A3VL-sheep) in which the anterior third ventricle wall had been ablated. Dehydrated A3VL-sheep exhibited a much greater degree of hypernatremia than dehydrated normal sheep, although w...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(83)90326-8

    authors: McKinley MJ,Denton DA,Park RG,Weisinger RS

    更新日期:1983-03-21 00:00:00